메뉴 건너뛰기




Volumn 107, Issue 45, 2010, Pages 19543-19548

Duration of estrogen deprivation, not chronological age, prevents estrogen's ability to enhance hippocampal synaptic physiology

Author keywords

Aging; Estradiol; Long term potentiation; NR2B; Spines

Indexed keywords

ESTROGEN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B;

EID: 78650592833     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1009307107     Document Type: Article
Times cited : (75)

References (55)
  • 1
    • 0027052984 scopus 로고
    • Variations in memory function and sex steroid hormones across the menstrual cycle
    • Phillips SM, Sherwin BB (1992) Variations in memory function and sex steroid hormones across the menstrual cycle. Psychoneuroendocrinology 17:497-506.
    • (1992) Psychoneuroendocrinology , vol.17 , pp. 497-506
    • Phillips, S.M.1    Sherwin, B.B.2
  • 2
    • 0036808858 scopus 로고    scopus 로고
    • Verbal and spatial functions across the menstrual cycle in healthy young women
    • Rosenberg L, Park S (2002) Verbal and spatial functions across the menstrual cycle in healthy young women. Psychoneuroendocrinology 27:835-841.
    • (2002) Psychoneuroendocrinology , vol.27 , pp. 835-841
    • Rosenberg, L.1    Park, S.2
  • 3
    • 0036615277 scopus 로고    scopus 로고
    • The effects of estrogen replacement therapy on neuropsychological functioning in postmenopausal women with and without dementia: A critical and theoretical review
    • Zec RF, Trivedi MA (2002) The effects of estrogen replacement therapy on neuropsychological functioning in postmenopausal women with and without dementia: A critical and theoretical review. Neuropsychol Rev 12:65-109.
    • (2002) Neuropsychol Rev , vol.12 , pp. 65-109
    • Zec, R.F.1    Trivedi, M.A.2
  • 4
    • 0038386058 scopus 로고    scopus 로고
    • WHIMS Investigators
    • Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women. The Women's Health Initiative Memory Study: A randomized controlled trial
    • Shumaker SA, et al.; WHIMS Investigators (2003) Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women. The Women's Health Initiative Memory Study: A randomized controlled trial. JAMA 289:2651-2662.
    • (2003) JAMA , vol.289 , pp. 2651-2662
    • Shumaker, S.A.1
  • 5
    • 2942755831 scopus 로고    scopus 로고
    • Women's health initiative memory study
    • Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study
    • Shumaker SA, et al.; Women's Health Initiative Memory Study (2004) Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study. JAMA 291: 2947-2958.
    • (2004) JAMA , vol.291 , pp. 2947-2958
    • Shumaker, S.A.1
  • 6
    • 33846001358 scopus 로고    scopus 로고
    • The critical period hypothesis: Can it explain discrepancies in the oestrogen-cognition literature?
    • Sherwin BB (2007) The critical period hypothesis: Can it explain discrepancies in the oestrogen-cognition literature? J Neuroendocrinol 19:77-81.
    • (2007) J Neuroendocrinol , vol.19 , pp. 77-81
    • Sherwin, B.B.1
  • 7
    • 77449147924 scopus 로고    scopus 로고
    • Oophorectomy, menopause, estrogen, and cognitive aging: The timing hypothesis
    • RoccaWA, Grossardt BR, Shuster LT (2010) Oophorectomy, menopause, estrogen, and cognitive aging: The timing hypothesis. Neurodegener Dis 7:163-166.
    • (2010) Neurodegener Dis , vol.7 , pp. 163-166
    • Rocca, W.A.1    Grossardt, B.R.2    Shuster, L.T.3
  • 8
    • 0031416975 scopus 로고    scopus 로고
    • Estrogen enhances performance of female rats during acquisition of a radial arm maze
    • Daniel JM, Fader AJ, Spencer AL, Dohanich GP (1997) Estrogen enhances performance of female rats during acquisition of a radial arm maze. Horm Behav 32:217-225.
    • (1997) Horm Behav , vol.32 , pp. 217-225
    • Daniel, J.M.1    Fader, A.J.2    Spencer, A.L.3    Dohanich, G.P.4
  • 9
    • 0035035186 scopus 로고    scopus 로고
    • Memory retention is modulated by acute estradiol and progesterone replacement
    • Sandstrom NJ, Williams CL (2001) Memory retention is modulated by acute estradiol and progesterone replacement. Behav Neurosci 115:384-393.
    • (2001) Behav Neurosci , vol.115 , pp. 384-393
    • Sandstrom, N.J.1    Williams, C.L.2
  • 10
    • 0037998956 scopus 로고    scopus 로고
    • Rapid enhancement of visual and place memory by estrogens in rats
    • Luine VN, Jacome LF, Maclusky NJ (2003) Rapid enhancement of visual and place memory by estrogens in rats. Endocrinology 144:2836-2844.
    • (2003) Endocrinology , vol.144 , pp. 2836-2844
    • Luine, V.N.1    Jacome, L.F.2    Maclusky, N.J.3
  • 11
    • 33646840883 scopus 로고    scopus 로고
    • Ovarian steroids enhance object recognition in naturally cycling and ovariectomized, hormone-primed rats
    • Walf AA, Rhodes ME, Frye CA (2006) Ovarian steroids enhance object recognition in naturally cycling and ovariectomized, hormone-primed rats. Neurobiol Learn Mem 86:35-46.
    • (2006) Neurobiol Learn Mem , vol.86 , pp. 35-46
    • Walf, A.A.1    Rhodes, M.E.2    Frye, C.A.3
  • 12
    • 0034594465 scopus 로고    scopus 로고
    • Long-term treatment with estrogen and progesterone enhances acquisition of a spatial memory task by ovariectomized aged rats
    • Gibbs RB (2000) Long-term treatment with estrogen and progesterone enhances acquisition of a spatial memory task by ovariectomized aged rats. Neurobiol Aging 21:107-116.
    • (2000) Neurobiol Aging , vol.21 , pp. 107-116
    • Gibbs, R.B.1
  • 13
    • 67349142096 scopus 로고    scopus 로고
    • Donepezil treatment restores the ability of estradiol to enhance cognitive performance in aged rats: Evidence for the cholinergic basis of the critical period hypothesis
    • Gibbs RB, Mauk R, Nelson D, Johnson DA (2009) Donepezil treatment restores the ability of estradiol to enhance cognitive performance in aged rats: Evidence for the cholinergic basis of the critical period hypothesis. Horm Behav 56:73-83.
    • (2009) Horm Behav , vol.56 , pp. 73-83
    • Gibbs, R.B.1    Mauk, R.2    Nelson, D.3    Johnson, D.A.4
  • 14
    • 29344433831 scopus 로고    scopus 로고
    • Estradiol replacement enhances working memory in middle-aged rats when initiated immediately after ovariectomy but not after a long-term period of ovarian hormone deprivation
    • Daniel JM, Hulst JL, Berbling JL (2006) Estradiol replacement enhances working memory in middle-aged rats when initiated immediately after ovariectomy but not after a long-term period of ovarian hormone deprivation. Endocrinology 147: 607-614.
    • (2006) Endocrinology , vol.147 , pp. 607-614
    • Daniel, J.M.1    Hulst, J.L.2    Berbling, J.L.3
  • 15
    • 0038520900 scopus 로고    scopus 로고
    • The cognitive effects of ovariectomy and estrogen replacement are modulated by aging
    • Savonenko AV, Markowska AL (2003) The cognitive effects of ovariectomy and estrogen replacement are modulated by aging. Neuroscience 119:821-830.
    • (2003) Neuroscience , vol.119 , pp. 821-830
    • Savonenko, A.V.1    Markowska, A.L.2
  • 16
    • 0018344553 scopus 로고
    • Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat
    • Barnes CA (1979) Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat. J Comp Physiol Psychol 93:74-104.
    • (1979) J Comp Physiol Psychol , vol.93 , pp. 74-104
    • Barnes, C.A.1
  • 17
    • 0036456204 scopus 로고    scopus 로고
    • Regulation of synaptic plasticity in memory and memory decline with aging
    • Foster TC (2002) Regulation of synaptic plasticity in memory and memory decline with aging. Prog Brain Res 138:283-303.
    • (2002) Prog Brain Res , vol.138 , pp. 283-303
    • Foster, T.C.1
  • 18
    • 5344241223 scopus 로고    scopus 로고
    • LTP and LTD: An embarrassment of riches
    • Malenka RC, Bear MF (2004) LTP and LTD: An embarrassment of riches. Neuron 44: 5-21.
    • (2004) Neuron , vol.44 , pp. 5-21
    • Malenka, R.C.1    Bear, M.F.2
  • 19
    • 0028879385 scopus 로고
    • LTP varies across the estrous cycle: Enhanced synaptic plasticity in proestrus rats
    • Warren SG, Humphreys AG, Juraska JM, Greenough WT (1995) LTP varies across the estrous cycle: Enhanced synaptic plasticity in proestrus rats. Brain Res 703:26-30.
    • (1995) Brain Res , vol.703 , pp. 26-30
    • Warren, S.G.1    Humphreys, A.G.2    Juraska, J.M.3    Greenough, W.T.4
  • 20
    • 0035818486 scopus 로고    scopus 로고
    • Cyclic changes in estradiol regulate synaptic plasticity through the MAP kinase pathway
    • Bi R, Foy MR, Vouimba RM, Thompson RF, Baudry M (2001) Cyclic changes in estradiol regulate synaptic plasticity through the MAP kinase pathway. Proc Natl Acad Sci USA 98:13391-13395.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13391-13395
    • Bi, R.1    Foy, M.R.2    Vouimba, R.M.3    Thompson, R.F.4    Baudry, M.5
  • 21
    • 0031578768 scopus 로고    scopus 로고
    • Estrogen facilitates induction of long-term potentiation in the hippocampus of awake rats
    • Córdoba Montoya DA, Carrer HF (1997) Estrogen facilitates induction of long-term potentiation in the hippocampus of awake rats. Brain Res 778:430-438.
    • (1997) Brain Res , vol.778 , pp. 430-438
    • Córdoba Montoya, D.A.1    Carrer, H.F.2
  • 22
    • 0025411855 scopus 로고
    • Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood
    • Gould E, Woolley CS, Frankfurt M, McEwen BS (1990) Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood. J Neurosci 10: 1286-1291.
    • (1990) J Neurosci , vol.10 , pp. 1286-1291
    • Gould, E.1    Woolley, C.S.2    Frankfurt, M.3    McEwen, B.S.4
  • 23
    • 23944493635 scopus 로고    scopus 로고
    • Estrogen-induced increase in the magnitude of longterm potentiation occurs only when the ratio of NMDA transmission to AMPA transmission is increased
    • Smith CC, McMahon LL (2005) Estrogen-induced increase in the magnitude of longterm potentiation occurs only when the ratio of NMDA transmission to AMPA transmission is increased. J Neurosci 25:7780-7791.
    • (2005) J Neurosci , vol.25 , pp. 7780-7791
    • Smith, C.C.1    McMahon, L.L.2
  • 24
    • 0026627947 scopus 로고
    • Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat
    • Woolley CS, McEwen BS (1992) Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat. J Neurosci 12:2549-2554.
    • (1992) J Neurosci , vol.12 , pp. 2549-2554
    • Woolley, C.S.1    McEwen, B.S.2
  • 25
    • 0034724442 scopus 로고    scopus 로고
    • The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen in hippocampus
    • Bi R, Broutman G, Foy MR, Thompson RF, Baudry M (2000) The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen in hippocampus. Proc Natl Acad Sci USA 97:3602-3607.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3602-3607
    • Bi, R.1    Broutman, G.2    Foy, M.R.3    Thompson, R.F.4    Baudry, M.5
  • 26
    • 33748159197 scopus 로고    scopus 로고
    • Estradiol-induced increase in the magnitude of longterm potentiation is prevented by blocking NR2B-containing receptors
    • Smith CC, McMahon LL (2006) Estradiol-induced increase in the magnitude of longterm potentiation is prevented by blocking NR2B-containing receptors. J Neurosci 26: 8517-8522.
    • (2006) J Neurosci , vol.26 , pp. 8517-8522
    • Smith, C.C.1    McMahon, L.L.2
  • 27
    • 78650602096 scopus 로고    scopus 로고
    • Estradiol potentiation of NR2B-dependent EPSCs is not due to changes in NR2B protein expression or phosphorylation
    • 10.1002/hipo.20756
    • Snyder MA, Cooke BM, Woolley CS (2010) Estradiol potentiation of NR2B-dependent EPSCs is not due to changes in NR2B protein expression or phosphorylation. Hippocampus, 10.1002/hipo.20756.
    • (2010) Hippocampus
    • Snyder, M.A.1    Cooke, B.M.2    Woolley, C.S.3
  • 28
    • 0033517366 scopus 로고    scopus 로고
    • Genetic enhancement of learning and memory in mice
    • Tang YP, et al. (1999) Genetic enhancement of learning and memory in mice. Nature 401:63-69.
    • (1999) Nature , vol.401 , pp. 63-69
    • Tang, Y.P.1
  • 29
    • 0037439744 scopus 로고    scopus 로고
    • Associative memory formation increases the observation of dendritic spines in the hippocampus
    • Leuner B, Falduto J, Shors TJ (2003) Associative memory formation increases the observation of dendritic spines in the hippocampus. J Neurosci 23:659-665.
    • (2003) J Neurosci , vol.23 , pp. 659-665
    • Leuner, B.1    Falduto, J.2    Shors, T.J.3
  • 30
    • 77952549112 scopus 로고    scopus 로고
    • The beneficial effects of estradiol on attentional processes are dependent on timing of treatment initiation following ovariectomy in middle-aged rats
    • Bohacek J, Daniel JM (2010) The beneficial effects of estradiol on attentional processes are dependent on timing of treatment initiation following ovariectomy in middle-aged rats. Psychoneuroendocrinology 35:694-705.
    • (2010) Psychoneuroendocrinology , vol.35 , pp. 694-705
    • Bohacek, J.1    Daniel, J.M.2
  • 31
    • 7244224718 scopus 로고    scopus 로고
    • Aging-related changes in ovarian hormones, their receptors, and neuroendocrine function
    • Chakraborty TR, Gore AC (2004) Aging-related changes in ovarian hormones, their receptors, and neuroendocrine function. Exp Biol Med (Maywood) 229:977-987.
    • (2004) Exp Biol Med (Maywood) , vol.229 , pp. 977-987
    • Chakraborty, T.R.1    Gore, A.C.2
  • 32
    • 77956180117 scopus 로고    scopus 로고
    • The critical period hypothesis of estrogen effects on cognition: Insights from basic research
    • Daniel JM, Bohacek J (2010) The critical period hypothesis of estrogen effects on cognition: Insights from basic research. Biochim Biophys Acta Gen Subj, 1800:1068-1076
    • (2010) Biochim Biophys Acta Gen Subj , vol.1800 , pp. 1068-1076
    • Daniel, J.M.1    Bohacek, J.2
  • 33
    • 77956173928 scopus 로고    scopus 로고
    • A new approach to understanding the molecular mechanisms through which estrogens affect cognition
    • Frick KM, Fernandez SM, Harburger LL (2010) A new approach to understanding the molecular mechanisms through which estrogens affect cognition. Biochim Biophys Acta Gen Subj, 1800:1045-1055.
    • (2010) Biochim Biophys Acta Gen Subj , vol.1800 , pp. 1045-1055
    • Frick, K.M.1    Fernandez, S.M.2    Harburger, L.L.3
  • 34
    • 77952908171 scopus 로고    scopus 로고
    • Estrogen therapy and cognition: A review of the cholinergic hypothesis
    • Gibbs RB (2010) Estrogen therapy and cognition: A review of the cholinergic hypothesis. Endocr Rev 31:224-253.
    • (2010) Endocr Rev , vol.31 , pp. 224-253
    • Gibbs, R.B.1
  • 35
    • 0025617479 scopus 로고
    • Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons
    • Woolley CS, Gould E, Frankfurt M, McEwen BS (1990) Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons. J Neurosci 10: 4035-4039.
    • (1990) J Neurosci , vol.10 , pp. 4035-4039
    • Woolley, C.S.1    Gould, E.2    Frankfurt, M.3    McEwen, B.S.4
  • 36
    • 0034810063 scopus 로고    scopus 로고
    • Postsynaptic conversion of silent synapses during LTP affects synaptic gain and transmission dynamics
    • Poncer JC, Malinow R (2001) Postsynaptic conversion of silent synapses during LTP affects synaptic gain and transmission dynamics. Nat Neurosci 4:989-996.
    • (2001) Nat Neurosci , vol.4 , pp. 989-996
    • Poncer, J.C.1    Malinow, R.2
  • 37
    • 2642562084 scopus 로고    scopus 로고
    • Estrogen modulates synaptic N-methyl-D-aspartate receptor subunit distribution in the aged hippocampus
    • Adams MM, Fink SE, Janssen WG, Shah RA, Morrison JH (2004) Estrogen modulates synaptic N-methyl-D-aspartate receptor subunit distribution in the aged hippocampus. J Comp Neurol 474:419-426.
    • (2004) J Comp Neurol , vol.474 , pp. 419-426
    • Adams, M.M.1    Fink, S.E.2    Janssen, W.G.3    Shah, R.A.4    Morrison, J.H.5
  • 38
    • 47549084402 scopus 로고    scopus 로고
    • Assessment of estradiol influence on spatial tasks and hippocampal CA1 spines: Evidence that the duration of hormone deprivation after ovariectomy compromises 17beta-estradiol effectiveness in altering CA1 spines
    • McLaughlin KJ, Bimonte-Nelson H, Neisewander JL, Conrad CD (2008) Assessment of estradiol influence on spatial tasks and hippocampal CA1 spines: Evidence that the duration of hormone deprivation after ovariectomy compromises 17beta-estradiol effectiveness in altering CA1 spines. Horm Behav 54:386-395.
    • (2008) Horm Behav , vol.54 , pp. 386-395
    • McLaughlin, K.J.1    Bimonte-Nelson, H.2    Neisewander, J.L.3    Conrad, C.D.4
  • 39
    • 0034946795 scopus 로고    scopus 로고
    • Different modes of hippocampal plasticity in response to estrogen in young and aged female rats
    • Adams MM, Shah RA, Janssen WG, Morrison JH (2001) Different modes of hippocampal plasticity in response to estrogen in young and aged female rats. Proc Natl Acad Sci USA 98:8071-8076.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8071-8076
    • Adams, M.M.1    Shah, R.A.2    Janssen, W.G.3    Morrison, J.H.4
  • 40
    • 0035449911 scopus 로고    scopus 로고
    • Acetylcholine mediates the estrogen-induced increase in NMDA receptor binding in CA1 of the hippocampus and the associated improvement in working memory
    • Daniel JM, Dohanich GP (2001) Acetylcholine mediates the estrogen-induced increase in NMDA receptor binding in CA1 of the hippocampus and the associated improvement in working memory. J Neurosci 21:6949-6956.
    • (2001) J Neurosci , vol.21 , pp. 6949-6956
    • Daniel, J.M.1    Dohanich, G.P.2
  • 41
    • 77149138335 scopus 로고    scopus 로고
    • Does short-term estrogen therapy produce lasting benefits in brain?
    • Gibbs RB (2010) Does short-term estrogen therapy produce lasting benefits in brain? Endocrinology 151:843-845.
    • (2010) Endocrinology , vol.151 , pp. 843-845
    • Gibbs, R.B.1
  • 42
    • 63549150780 scopus 로고    scopus 로고
    • Activational and organisational effects of gonadal steroids on sex-specific acetylcholine release in the dorsal hippocampus
    • Mitsushima D, Takase K, Takahashi T, Kimura F (2009) Activational and organisational effects of gonadal steroids on sex-specific acetylcholine release in the dorsal hippocampus. J Neuroendocrinol 21:400-405.
    • (2009) J Neuroendocrinol , vol.21 , pp. 400-405
    • Mitsushima, D.1    Takase, K.2    Takahashi, T.3    Kimura, F.4
  • 43
    • 0141540548 scopus 로고    scopus 로고
    • Short-term estrogen treatment in ovariectomized rats augments hippocampal acetylcholine release during place learning
    • Marriott LK, Korol DL (2003) Short-term estrogen treatment in ovariectomized rats augments hippocampal acetylcholine release during place learning. Neurobiol Learn Mem 80:315-322.
    • (2003) Neurobiol Learn Mem , vol.80 , pp. 315-322
    • Marriott, L.K.1    Korol, D.L.2
  • 44
    • 0032103915 scopus 로고    scopus 로고
    • Impairment of basal forebrain cholinergic neurons associated with aging and long-term loss of ovarian function
    • Gibbs RB (1998) Impairment of basal forebrain cholinergic neurons associated with aging and long-term loss of ovarian function. Exp Neurol 151:289-302.
    • (1998) Exp Neurol , vol.151 , pp. 289-302
    • Gibbs, R.B.1
  • 45
    • 0030818062 scopus 로고    scopus 로고
    • Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease
    • Simpkins JW, et al. (1997) Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease. Am J Med 103(3A):19S-25S.
    • (1997) Am J Med , vol.103 , Issue.3 A
    • Simpkins, J.W.1
  • 46
    • 33750445930 scopus 로고    scopus 로고
    • The significance of the cholinergic system in the brain during aging and in Alzheimer's disease
    • Schliebs R, Arendt T (2006) The significance of the cholinergic system in the brain during aging and in Alzheimer's disease. J Neural Transm 113:1625-1644.
    • (2006) J Neural Transm , vol.113 , pp. 1625-1644
    • Schliebs, R.1    Arendt, T.2
  • 47
    • 0033925854 scopus 로고    scopus 로고
    • The estrogen replacement therapy of the Women's Health Initiative promotes the cellular mechanisms of memory andneuronal survival inneurons vulnerable to Alzheimer's disease
    • Brinton RD, Chen S, Montoya M, Hsieh D, Minaya J (2000) The estrogen replacement therapy of the Women's Health Initiative promotes the cellular mechanisms of memory andneuronal survival inneurons vulnerable to Alzheimer'sdisease.Maturitas 34 (Suppl 2):S35-S52.
    • (2000) Maturitas , vol.34 , Issue.SUPPL. 2
    • Brinton, R.D.1    Chen, S.2    Montoya, M.3    Hsieh, D.4    Minaya, J.5
  • 48
    • 18044389696 scopus 로고    scopus 로고
    • Estrogen and cognition, with a focus on Alzheimer's disease
    • Pinkerton JV, Henderson VW (2005) Estrogen and cognition, with a focus on Alzheimer's disease. Semin Reprod Med 23:172-179.
    • (2005) Semin Reprod Med , vol.23 , pp. 172-179
    • Pinkerton, J.V.1    Henderson, V.W.2
  • 49
    • 13144257746 scopus 로고    scopus 로고
    • Similarities between actions of estrogen and BDNF in the hippocampus: Coincidence or clue?
    • Scharfman HE, Maclusky NJ (2005) Similarities between actions of estrogen and BDNF in the hippocampus: Coincidence or clue? Trends Neurosci 28:79-85.
    • (2005) Trends Neurosci , vol.28 , pp. 79-85
    • Scharfman, H.E.1    Maclusky, N.J.2
  • 50
    • 34247887363 scopus 로고    scopus 로고
    • Beta-estradiol induces synaptogenesis in the hippocampus by enhancing brain-derived neurotrophic factor release from dentate gyrus granule cells
    • Sato K, Akaishi T, Matsuki N, Ohno Y, Nakazawa K (2007) Beta-estradiol induces synaptogenesis in the hippocampus by enhancing brain-derived neurotrophic factor release from dentate gyrus granule cells. Brain Res 1150:108-120.
    • (2007) Brain Res , vol.1150 , pp. 108-120
    • Sato, K.1    Akaishi, T.2    Matsuki, N.3    Ohno, Y.4    Nakazawa, K.5
  • 51
    • 0034329490 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor increases activity of NR2Bcontaining N-methyl-D-aspartate receptors in excised patches from hippocampal neurons
    • Levine ES, Kolb JE (2000) Brain-derived neurotrophic factor increases activity of NR2Bcontaining N-methyl-D-aspartate receptors in excised patches from hippocampal neurons. J Neurosci Res 62:357-362.
    • (2000) J Neurosci Res , vol.62 , pp. 357-362
    • Levine, E.S.1    Kolb, J.E.2
  • 52
    • 0036742611 scopus 로고    scopus 로고
    • From acquisition to consolidation: On the role of brain-derived neurotrophic factor signaling in hippocampaldependent learning
    • Tyler WJ, Alonso M, Bramham CR, Pozzo-Miller LD (2002) From acquisition to consolidation:Onthe role of brain-derived neurotrophic factor signaling in hippocampaldependent learning. Learn Mem 9:224-237.
    • (2002) Learn Mem , vol.9 , pp. 224-237
    • Tyler, W.J.1    Alonso, M.2    Bramham, C.R.3    Pozzo-Miller, L.D.4
  • 53
    • 0347694857 scopus 로고    scopus 로고
    • Hippocampal excitability increases during the estrous cycle in the rat: A potential role for brain-derived neurotrophic factor
    • Scharfman HE, Mercurio TC, Goodman JH, Wilson MA, MacLusky NJ (2003) Hippocampal excitability increases during the estrous cycle in the rat: A potential role for brain-derived neurotrophic factor. J Neurosci 23:11641-11652.
    • (2003) J Neurosci , vol.23 , pp. 11641-11652
    • Scharfman, H.E.1    Mercurio, T.C.2    Goodman, J.H.3    Wilson, M.A.4    MacLusky, N.J.5
  • 54
    • 3042717140 scopus 로고    scopus 로고
    • Hippocampal synapses depend on hippocampal estrogen synthesis
    • Kretz O, et al. (2004) Hippocampal synapses depend on hippocampal estrogen synthesis. J Neurosci 24:5913-5921.
    • (2004) J Neurosci , vol.24 , pp. 5913-5921
    • Kretz, O.1
  • 55
    • 0027445017 scopus 로고
    • Roles of estradiol and progesterone in regulation of hippocampal dendritic spine density during the estrous cycle in the rat
    • Woolley CS, McEwen BS (1993) Roles of estradiol and progesterone in regulation of hippocampal dendritic spine density during the estrous cycle in the rat. J Comp Neurol 336:293-306.
    • (1993) J Comp Neurol , vol.336 , pp. 293-306
    • Woolley, C.S.1    McEwen, B.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.