G protein-coupled estrogen receptor1 (GPER1) may mediate Rho-kinase (ROCK-2) up-regulation in coronary endothelial cells

Endocrine Regulations

Volumn 47, Issue 2, 2013, Pages 75-84

  Kurt, A H ^a   Tiftik, R N ^a   Un, I ^a   Ulker, S ^b   Buyukafsar, K ^a  

^a Mersin University Campus ^*  (Turkey)

^b EGE UNIVERSITY   (Turkey)

Author keywords

17 estradiol; Endothelium; GPER1; ICI 182780; Rho kinase

Indexed keywords

1, 3, 5 TRIS (4 HYDROXYPHENYL) 4 PROPYLPYRAZOLE; BOVINE SERUM ALBUMIN; DACTINOMYCIN; DIARYLPROPIONITRILE; EPIDERMAL GROWTH FACTOR RECEPTOR; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; G PROTEIN COUPLED RECEPTOR 30; NITRIC OXIDE; PERTUSSIS TOXIN; PROGESTERONE; PROTEIN INHIBITOR; RHO KINASE; SUPEROXIDE DISMUTASE; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENETIC TRANSCRIPTION; MALE; NONHUMAN; RAT; WESTERN BLOTTING;

ANIMALS; BENZODIOXOLES; CELL MOVEMENT; CELLS, CULTURED; CORONARY CIRCULATION; DACTINOMYCIN; ENDOTHELIAL CELLS; ENZYME INHIBITORS; ESTRADIOL; ESTROGEN ANTAGONISTS; MALE; NITRIC OXIDE; NITRILES; PROGESTERONE; PROTEIN SYNTHESIS INHIBITORS; PYRAZOLES; QUINAZOLINES; QUINOLINES; RATS; RATS, WISTAR; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, G-PROTEIN-COUPLED; RHO-ASSOCIATED KINASES; TESTOSTERONE; TYRPHOSTINS; UP-REGULATION;

EID: 84878422740     PISSN: 12100668     EISSN: 13360329     Source Type: Journal    
DOI: 10.4149/endo_2013_02_75     Document Type: Article

References (41)

1. Brouchet L, Krust A, Dupont S, Chambon P, Bayard F, Arnal JF: Estradiol accelerates reendothelization in mouse carotid artery through estrogen receptor α but not estrogen receptor β. Circulation 103, 423-428, 2001. http://dx.doi. org/10.1161/01.CIR.103.3.423
2. Broughton BRS, Miller AA, Sobey CG: Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries. Am J Physiol Heart Circ Physiol 298, 1055-1061, 2010. http://dx.doi.org/10.1152/ajp-heart.00878.2009
3. Buyukafsar K, Nelli S, Martin W: Formation of nitric oxide from nitroxyl anion: role of quinones and ferricytochrome c. Br J Pharmacol 132, 165-172, 2001. http://dx.doi.org/10.1038/sj.bjp.0703812
4. Buyukafsar K, Arikan O, Ark M, Secilmis A, Un I, Singirik E: Rho-kinase expression and its contribution to the control of perfusion pressure in the isolated rat mesenteric vascular bed. Eur J Pharmacol 485, 263-268, 2004. http:// dx.doi.org/10.1016/j.ejphar.2003.11.076
5. Carmeci C, Tompson DA, Ring HZ, Francke U, Weigel RJ: Identifcation of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer. Genomics 45, 607-617, 1997. http://dx.doi.org/10.1006/geno.1997.4972
6. Caulin-Glaser T, Garcia-Cardena G, Sarrel P, Sessa WC, Bender JR: 17beta-estradiol regulation of human endothelial cell basal nitric oxide release, independent of cytosolic Ca2+ mobilization. Circ Res 81, 885-892, 1997. http:// dx.doi.org/10.1161/01.RES.81.5.885
7. Chrissobolis S, Budzyn K, Marley PD, Sobey CG: Evidence that estrogen suppresses Rho-kinase function in the cerebral circulation in vivo. Stroke 35, 2200-2205, 2004. http://dx.doi.org/10.1161/01.STR.0000136951.85586.c8
8. Filardo EJ: Epidermal growth factor receptor (EGFR) transactivation by estrogen via the G-protein-coupled receptor, GPR30: a novel signaling pathway with potential signifcance for breast cancer. J Steroid Biochem Mol Biol 80, 231-238, 2002. http://dx.doi.org/10.1016/S0960-0760(01)00190-X
9. Filardo EJ, Quinn JA, Bland KI, Frackelton AR: Estrogen-induced activation of Erk-1 and Erk-2 regulates the protein-coupled receptor homolog GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol 14, 1649-1660, 2000. http://dx.doi.org/10.1210/me.14.10.1649
10. Frasor J, Barnett DH, Danes JM, Hess R, Parlow AF, Katzenellenbogen BS: Response-specifc and ligand dose-dependent modulation of estrogen receptor (ER) alpha activity by ERbeta in the uterus. Endocrinology 144, 3159-3166, 2003. http://dx.doi.org/10.1210/en.2002-0143
11. Fritz G, Just I, Kaina B: Rho GTPases are over-expressed in human tumors. Int J Cancer 81, 682-687, 1999. http://dx.doi. org/10.1002/(SICI)1097-0215(19990531)81:5682::AID-IJC23.0.CO;2-B
12. Fu XD, Simoncini T: Non-genomic sex steroid actions in the vascular system. Reprod Med 25, 178-186, 2007. http:// dx.doi.org/10.1055/s-2007-973430
13. Fu XD, Flamini M, Sanchez AM, Goglia L, Giretti MS, Genazzani AR, Simoncini T: Progestogens regulate endothelial actin cytoskeleton and cell movement via the actin-binding protein moesin. Mol Hum Reproduc 14, 225-234, 2008. http://dx.doi.org/10.1093/molehr/gan010
14. Fukata Y, Amano M, Kaibuchi K: Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells. Trends Pharmacol Sci 22, 32-39, 2001. http://dx.doi.org/10.1016/S0165-6147(00)01596-0
15. Geraldes P, Sirois MG, Bernatchez PN, Tanguay JF: Estrogen regulation of endothelial and smooth muscle cell migration and proliferation: role of p38 and p42/44 mitogen-activated protein kinase. Arterioscler Tromb Vasc Biol 22, 1585-1590, 2002. http://dx.doi.org/10.1161/01.ATV.0000035393.11854.6A
16. Grandien K, Berkenstam A, Gustafsson JA: Te estrogen receptor gene: promoter organization and expression. Int J Biochem Cell Biol 29, 1343-1369, 1997. http://dx.doi.org/10.1016/S1357-2725(97)89967-0
17. Greco TL, Duello TM, Gorski J: Estrogen receptors, estradiol, and diethylstilbestrol in early development: the mouse as a model for the study of estrogen receptors and estrogen sensitivity in embryonic development of male and female reproductive tracts. Endocrin Rev 14, 59-71, 1993.
18. Hall JM, Couse JF, Korach KS: Te multifaceted mechanisms of estradiol and estrogen receptor signaling. J Biol Chem 276, 36869-36872, 2001. http://dx.doi.org/10.1074/jbc.R100029200
19. Hiroki J, Shimokawa H, Mukai Y, Ichiki T, Takeshita A: Divergent efects of estrogen and nicotine on Rho-kinase expression in human coronary vascular smooth muscle cells. Biochem Biophys Res Commun 326, 154-159, 2005. http:// dx.doi.org/10.1016/j.bbrc.2004.11.011
20. Hiroko J, Shimokawa H, Higashi K, Morikawa T, Kandabashi T, Kawamura N, Kubota T, Ichiki T, Mutsukji A, Kaibuchi K, Takeshita A: Infammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells. J Mol Cell Cardiol 37, 537-546, 2004. http://dx.doi.org/10.1016/j.yjmcc.2004.05.008
21. Iafrati MD, Karas RH, Aronovitz M, Kim S, Sullivan TR Jr, Lubhan DB, O'Donnell TF Jr, Korach KS, Mendelsohn ME: Estrogen inhibits the vascular injury response in estrogen receptorß-defcient mice. Nat Med 3, 545-548, 1997. http://dx.doi.org/10.1038/nm0597-545
22. Kamango-Sollo E, White ME, Chung KY, Johnson BJ, Dayton WR: Potential role of G-protein-coupled receptor 30 (GPR30) in estradiol-17β-stimulated IGF-I mRNA expression in bovine satellite cell cultures. Domest Anim Endocrinol 35, 254-262, 2008. http://dx.doi.org/10.1016/j.domaniend.2008.06.001
23. Kamby C, Rasmussesn BB, Kristensen B: Oestrogen receptor status of primary breast carcinomas and their metas-tases. Relation to pattern of spread and survival afer recurrence. Br J Cancer 60, 252-257, 1989. http://dx.doi. org/10.1038/bjc.1989.264
24. Karas RH, Hodgin JB, Kwoun M, Krege JH, Aronovitz M, Mackey W, Gustafsson JA, Korach KS, Smithies O, Mendelsohn ME: Estrogen inhibits the vascular injury response in estrogen receptorß-defcient female mice. Proc Natl Acad Sci 96, 15133-15136, 1999. http://dx.doi.org/10.1073/pnas.96.26.15133
25. Karas RH, Schulten H, Pare G, Aronovitz MJ, Ohlsson C, Gustafsson JA, Mendelsohn ME: Efects of estrogen on the vascular injury response in estrogen receptor alpha, beta (double) knockout mice. Circ Res 14, 534-539, 2001. http://dx.doi.org/10.1161/hh1801.097239
26. Kelly MJ, Levin ER: Rapid actions of plasma membrane estrogen receptors. Trends Endocrinol Metab 12, 152-156, 2001. http://dx.doi.org/10.1016/S1043-2760(01)00377-0
27. Khan S, Wu F, Liu S, Wu Q, Safe S: Role of specifcity protein transcription factors in estrogen induced gene expression in MCF-7 breast cancer cells. J Mol Endocr 39, 289-304, 2007. http://dx.doi.org/10.1677/JME-07-0043
28. Kim-Schulze S, McGowan KA, Hubchak SC, Cid MC, Martin MB, Kleinman HK, Greene GI, Schnaper HW: Expression of estrogen receptors by human coronary artery and umbilical vein endothelial cells. Circulation 94, 1402-1407, 1996. http://dx.doi.org/10.1161/01.CIR.94.6.1402
29. Maggiolini M, Vivacqua A, Fasanella G, Recchia AG, Sisci D, Pezzi V, Montanaro D, Musti AM, Picard D, Ando S: Te G protein-coupled receptor GPR30 mediates c-fos-upregulation by 17beta estradiol and phytoestrogens in breast cancer cells. J Biol Chem 279, 27008-27016, 2004. http://dx.doi.org/10.1074/jbc.M403588200
30. Piper HM, Spahr R, Mertens S: Microvascular endothelial cells from the heart. In: Cell Culture Techniques in Heart and Vessel Research (Ed: HM Piper), pp. 158-177, Springer-Verlag 1990. http://dx.doi.org/10.1007/978-3-642-75262-9_11
31. Prossnitz ER, Arterburn JB, Smith HO, Oprea TI, Sklar LA, Hathaway HJ: Estrogen signaling through the transmembrane G protein-coupled receptor GPR30. Annu Rev Physiol 70, 165-190, 2008. http://dx.doi.org/10.1146/annurev. physiol.70.113006.100518
32. Revenkar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER: A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 307, 1625-1630, 2005. http://dx.doi.org/10.1126/science.1106943
33. Simoncini T, Rabkin E, Liao JK: Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinosi-tol 3-kinase in endothelial cells. Arterioscler Tromb Vasc Biol 23, 198-203, 2003. http://dx.doi.org/10.1161/01. ATV.0000053846.71621.93
34. Simoncini T, Mannella P, Fornari L, Caruso A, Varone G, Genazzani AR: Gemonic and non-genomic efects of estrogens on endothelial cells. Streoids 69, 537-542, 2004. http://dx.doi.org/10.1016/j.steroids.2004.05.009
35. Simoncini T, Scorticati C, Manndella P, Fadiel A, Giretti MS, Fu XD, Baldacci C, Garibaldi S, Caruso A, Fornari L, Nafolin F, Genazzani AR: Estrogen receptor a interacts with Ga13 to drive actin remodeling and endothelial cell migration via the RhoA/Rho kinase/moesin pathway. Mol Endocrinol 20, 1756-1771, 2006. http://dx.doi. org/10.1210/me.2005-0259
36. Tomas PY, Filardo EJ, Dong J: Identity of an estrogen membrane receptor coupled to a G-protein in human breast cancer cells. Endocrinology 146, 624-632, 2005. http://dx.doi.org/10.1210/en.2004-1064
37. Tifik N, Erol A, Cinar M, Kubat H, Ark M, Ulker S, Buyukafsar K: Nitric oxide does not down-regulated Rho-kinase (ROCK-2) expression in rat coronary endothelial cells. J Cardiovasc Pharmacol 51, 140-147, 2008. http://dx.doi. org/10.1097/FJC.0b013e31815e4089
38. Tsai EM, Wang SC, Lee JN, Hung MC: Akt activation by estrogen receptor-negative breast cancer cells. Cancer Res 61, 8390-8392, 2001.
39. Ulker S, McKeown P P, Bayraktutan U: Aprotinin impairs coronary endothelial function and downregulate endothelial NOS in rat coronary microvascular endothelial cells. Cardiovasc Res 55, 830-837, 2002. http://dx.doi.org/10.1016/ S0008-6363(02)00489-3
40. Van Nieuw Amerongen G P, Draijer R, Vermeer MA, van Hinsbergh VW: Transient and prolonged increase in endothe-lial permeability induced by histamine and thrombin: role of protein kinases, calcium, and RhoA. Circ Res 83, 1115-1123, 1998. http://dx.doi.org/10.1161/01.RES.83.11.1115
41. Van Nieuw Amerongen GP, Beckers CM, Achekar ID, Zeeman S, Musters RJ, van Hinsbergh VW: Involvement of Rho kinase in endothelial barrier maintenance. Arterioscler Tromb Vas Biol 27, 2332-2339, 2007. http://dx.doi. org/10.1161/ASTVBAHA.107.152322