Akt activation by estrogen in estrogen receptor-negative breast cancer cells

Cancer Research

Volumn 61, Issue 23, 2001, Pages 8390-8392

  Tsai, Eing Mei ^a   Lee, Jau Nan ^a   Wang, Shao Chun ^b   Hung, Mien Chie ^b  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTIESTROGEN; ESTROGEN; ESTROGEN RECEPTOR; FULVESTRANT; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHOSERINE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SERINE; TAMOXIFEN; WORTMANNIN;

APOPTOSIS; ARTICLE; BREAST CANCER; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BREAST NEOPLASMS; ENZYME ACTIVATION; ESTROGEN RECEPTOR ALPHA; ESTROGENS; HUMANS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, ESTROGEN; TUMOR CELLS, CULTURED;

EID: 0035576805     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Interleukin 3-dependent survival by the Akt protein kinase
2. The protein kinase encoded by the Akt protooncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
3. Mechanism of activation of protein kinase B by insulin and IGF-1
4. Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
5. Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons
6. Role of AKT: In 17β-estrodiol- and insulin-like growth factor I (IGF-I)-dependent proliferation and prevention of apoptosis in MCF-7 breast carcinoma cells
7. Estrogen-induced activation of the mitogen-activated protein kinase cascade in the cerebral cortex of estrogen receptor-α knock-out mice
8. Tamoxifen and its active metabolite inhibit growth of estrogen receptor-negative MDA-MB-435 cells
9. Expression and regulation of estrogen receptor β in human breast tumors and cell lines
10. Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogenstimulated proliferation of human breast cancer cells
11. Adhesion-linked kinases in cancer; emphasis on Src, focal adhesion kinase and PI 3-kinase
12. Bombesin and platelet-derived growth factor induce association of endogenous focal adhesion kinase with Src in intact Swiss 3T3 cells
13. Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-henylamino)pyradolo[3, 4-d]pyrimidines
14. WAFI expression via Spl-binding sites by tamoxifen in estrogen receptor-negative lung cancer cells