Celastrol induced DNA damage, cell cycle arrest, and apoptosis in human rheumatoid fibroblast-like synovial cells

American Journal of Chinese Medicine

Volumn 41, Issue 3, 2013, Pages 615-628

  Xu, Zengtao ^a,b   Wu, Guosheng ^b   Wei, Xu ^a   Chen, Xiuping ^b   Wang, Yitao ^b   Chen, Lidian ^a  

^a FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b University of Macau   (Macao)

Author keywords

Apoptosis; Celastrol; DNA Damage; Rheumatoid Fibroblast Like Synoviocytes

Indexed keywords

CASPASE 3; CASPASE 9; CELASTROL; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN TYROSINE PHOSPHATASE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL SHAPE; CELL VIABILITY; CHROMATIN; CONTROLLED STUDY; DNA CONTENT; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; GROWTH; GROWTH RATE; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN EXPRESSION; SYNOVIOCYTE;

ANTI-INFLAMMATORY AGENTS; ANTIRHEUMATIC AGENTS; APOPTOSIS; ARTHRITIS, RHEUMATOID; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL CYCLE CHECKPOINTS; CELL LINE; CELL SURVIVAL; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FIBROBLASTS; HUMANS; PHYTOTHERAPY; PROTO-ONCOGENE PROTEINS C-BCL-2; SYNOVIAL MEMBRANE; TRIPTERYGIUM; TRITERPENES;

EID: 84878414532     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X13500432     Document Type: Article

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