Structure-based prediction of the effects of a missense variant on protein stability

Amino Acids

Volumn 44, Issue 3, 2013, Pages 847-855

  Yang, Yang ^a   Chen, Biao ^a   Tan, Ge ^a,b   Vihinen, Mauno ^c,d,e   Shen, Bairong ^a,c  

^a SOOCHOW UNIVERSITY   (China)

^b TONGJI UNIVERSITY   (China)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^d LUND UNIVERSITY   (Sweden)

^e TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

Amino acid mutation; Physicochemical properties; Protein stability prediction; Residue residue contact energy; Support vector machine

Indexed keywords

AMINO ACID;

AMINO ACID SUBSTITUTION; ARTICLE; COMPUTER PROGRAM; KERNEL METHOD; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MEASUREMENT ACCURACY; PHYSICAL CHEMISTRY; PREDICTIVE VALUE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN ANALYSIS; PROTEIN STABILITY; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; STRUCTURE BASED PREDICTION; SUPPORT VECTOR MACHINE;

AMINO ACID SUBSTITUTION; ANIMALS; COMPUTATIONAL BIOLOGY; DATABASES, PROTEIN; HUMANS; MUTATION, MISSENSE; PROTEIN STABILITY; PROTEINS; SUPPORT VECTOR MACHINES;

EID: 84878362869     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-012-1407-7     Document Type: Article

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