Use of molecular modeling and site-directed mutagenesis to define the structural basis for the immune response to carbohydrate xenoantigens

BMC Immunology

Volumn 8, Issue , 2007, Pages

  Kearns Jonker, Mary ^a   Barteneva, Natasha ^a   Mencel, Robert ^a   Hussain, Namath ^a   Shulkin, Irina ^a   Xu, Alan ^a   Yew, Margaret ^a   Cramer, Donald V ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE ANTIGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN M; CARBOHYDRATE; EPITOPE; HETEROPHILE ANTIBODY; HETEROPHILE ANTIGEN;

ACCURACY; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOARTIFICIAL LIVER; COMPUTER PROGRAM; COMPUTER SIMULATION; CONTROLLED STUDY; DRUG SYNTHESIS; GERM LINE; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR MODEL; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; SOMATIC MUTATION; STRUCTURE ANALYSIS; XENOTRANSPLANTATION; ANIMAL; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; IMMUNOLOGY; MOLECULAR GENETICS; SWINE;

ANIMALS; ANTIBODIES, HETEROPHILE; ANTIGENS, HETEROPHILE; CARBOHYDRATES; CELLS, CULTURED; EPITOPES; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; SWINE;

EID: 34147216807     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/1471-2172-8-3     Document Type: Article

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