Transformation of the naturally occurring frog skin peptide, alyteserin-2a into a potent, non-toxic anti-cancer agent

Amino Acids

Volumn 44, Issue 2, 2013, Pages 715-723

  Conlon, J Michael ^a   Mechkarska, Milena ^a   Prajeep, Manju ^a   Arafat, Kholoud ^a   Zaric, Milan ^b   Lukic, Miodrag L ^c   Attoub, Samir ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b University of Kragujevac Medical Faculty   (Serbia)

^c UNIVERSITY OF KRAGUJEVAC   (Serbia)

Author keywords

Alyteserin 2a; Anticancer; Cell penetrating peptide; Structure activity

Indexed keywords

ALYTESERIN 2A; ANTINEOPLASTIC AGENT; INTERLEUKIN 10; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CANCER INHIBITION; CELL STRAIN HEPG2; COLORECTAL CARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIVER CELL CARCINOMA; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; UPREGULATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; ANTINEOPLASTIC AGENTS; ANURA; CELL LINE, TUMOR; HT29 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; NEOPLASMS; SKIN; STRUCTURE-ACTIVITY RELATIONSHIP;

ALYTES OBSTETRICANS; ANURA;

EID: 84878355317     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-012-1395-7     Document Type: Article

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