-
1
-
-
0029140694
-
Childhood leukemias
-
Pui C-H: Childhood leukemias. N Engl J Med 332:1618, 1995
-
(1995)
N Engl J Med
, vol.332
, pp. 1618
-
-
Pui, C.-H.1
-
2
-
-
0027351189
-
Karnofsky memorial lecture. Ode to methotrexate
-
Bertino JR: Karnofsky memorial lecture. Ode to methotrexate. J Clin Oncol 11:5, 1993
-
(1993)
J Clin Oncol
, vol.11
, pp. 5
-
-
Bertino, J.R.1
-
3
-
-
0016758663
-
Anti-folate resistance in leukemia: Treatment with "high-dose" methotrexate and citrovorum factor
-
Bender RA: Anti-folate resistance in leukemia: Treatment with "high-dose" methotrexate and citrovorum factor. Cancer Treat Rev 2:215, 1975
-
(1975)
Cancer Treat Rev
, vol.2
, pp. 215
-
-
Bender, R.A.1
-
4
-
-
0017735340
-
Natural resistance to methotrexate in human acute nonlymphocytic leukemia
-
Bertino JR, Sawicki WL, Cashmore AR, Cadman EC, Skeel, RT: Natural resistance to methotrexate in human acute nonlymphocytic leukemia. Cancer Treat Rep 61:667, 1977
-
(1977)
Cancer Treat Rep
, vol.61
, pp. 667
-
-
Bertino, J.R.1
Sawicki, W.L.2
Cashmore, A.R.3
Cadman, E.C.4
Skeel, R.T.5
-
5
-
-
0026342183
-
Basis for natural resistance to methotrexate in human acute non-lymphocytic leukemia
-
Lin JT, Tong WP, Trippett TM, Niedzwiecki D, Tao Y, Tan C, Steinherz P, Schweitzer BI, Bertino JR: Basis for natural resistance to methotrexate in human acute non-lymphocytic leukemia. Leuk Res 15:1191, 1991
-
(1991)
Leuk Res
, vol.15
, pp. 1191
-
-
Lin, J.T.1
Tong, W.P.2
Trippett, T.M.3
Niedzwiecki, D.4
Tao, Y.5
Tan, C.6
Steinherz, P.7
Schweitzer, B.I.8
Bertino, J.R.9
-
6
-
-
0028925157
-
Acute monocytic leukemia: A myeloid leukemia subset that may be sensitive to methotrexate
-
Goker E, Kheradpour A, Waltham M, Banerjee D, Tong WP, Elisseyeff Y, Bertino JR: Acute monocytic leukemia: A myeloid leukemia subset that may be sensitive to methotrexate. Leukemia 9:274, 1995
-
(1995)
Leukemia
, vol.9
, pp. 274
-
-
Goker, E.1
Kheradpour, A.2
Waltham, M.3
Banerjee, D.4
Tong, W.P.5
Elisseyeff, Y.6
Bertino, J.R.7
-
7
-
-
0024046260
-
In vitro methotrexate polyglutamate formation is elevated in acute lymphoid leukemia cells compared with acute myeloid leukemia and normal bone marrow cells
-
Yamauchi H, Iwata N, Omine M, Maekawa T: In vitro methotrexate polyglutamate formation is elevated in acute lymphoid leukemia cells compared with acute myeloid leukemia and normal bone marrow cells. Acta Haematol Jpn 51:756, 1988
-
(1988)
Acta Haematol Jpn
, vol.51
, pp. 756
-
-
Yamauchi, H.1
Iwata, N.2
Omine, M.3
Maekawa, T.4
-
8
-
-
0022410582
-
Polyglutamation of methotrexate. Is methotrexate a prodrug?
-
Chabner BA, Allegra CJ, Curt GA, Clendeninn NJ, Baram J, Koizumi S, Drake JC, Jolivet J: Polyglutamation of methotrexate. Is methotrexate a prodrug? J Clin Invest 76:907, 1985
-
(1985)
J Clin Invest
, vol.76
, pp. 907
-
-
Chabner, B.A.1
Allegra, C.J.2
Curt, G.A.3
Clendeninn, N.J.4
Baram, J.5
Koizumi, S.6
Drake, J.C.7
Jolivet, J.8
-
9
-
-
0025302665
-
Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: A pilot prognostic factor analysis
-
Whitehead VM, Rosenblatt DS, Vuhich M-J, Shuster JJ, Witte A, Beaulieu D: Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: A pilot prognostic factor analysis. Blood 76:44, 1990
-
(1990)
Blood
, vol.76
, pp. 44
-
-
Whitehead, V.M.1
Rosenblatt, D.S.2
Vuhich, M.-J.3
Shuster, J.J.4
Witte, A.5
Beaulieu, D.6
-
10
-
-
0030034467
-
Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo, a rational for high-dose methotrexate
-
Masson E, Relling MV, Synold TW, Liu Q, Schuetz JD, Sandlund JT, Pui C-H, Evans WE: Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo, a rational for high-dose methotrexate. J Clin Invest 97:73, 1996
-
(1996)
J Clin Invest
, vol.97
, pp. 73
-
-
Masson, E.1
Relling, M.V.2
Synold, T.W.3
Liu, Q.4
Schuetz, J.D.5
Sandlund, J.T.6
Pui, C.-H.7
Evans, W.E.8
-
11
-
-
0027317529
-
Decreased polyglutamylation of methotrexate in acute lymphoblastic leukemia blasts in adults compared to children with this disease
-
Goker E, Lin JT, Trippett T, Elisseyeff Y, Tong WP, Niedzwiecki D, Tan C, Steinherz P, Schweitzer BI, Bertino JR: Decreased polyglutamylation of methotrexate in acute lymphoblastic leukemia blasts in adults compared to children with this disease. Leukemia 7:1000, 1993
-
(1993)
Leukemia
, vol.7
, pp. 1000
-
-
Goker, E.1
Lin, J.T.2
Trippett, T.3
Elisseyeff, Y.4
Tong, W.P.5
Niedzwiecki, D.6
Tan, C.7
Steinherz, P.8
Schweitzer, B.I.9
Bertino, J.R.10
-
12
-
-
0028063423
-
Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia
-
Synold TW, Relling MV, Boyett JM, Rivera GK, Sandlund JT, Mahmoud H, Crist WM, Pui CH, Evans WE: Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia. J Clin Invest 94:1996, 1994
-
(1994)
J Clin Invest
, vol.94
, pp. 1996
-
-
Synold, T.W.1
Relling, M.V.2
Boyett, J.M.3
Rivera, G.K.4
Sandlund, J.T.5
Mahmoud, H.6
Crist, W.M.7
Pui, C.H.8
Evans, W.E.9
-
13
-
-
0030756226
-
Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: Mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity
-
Galpin AJ, Schuetz JD, Masson E, Yanishevski Y, Synold TW, Barredo JC, Pui CH, Relling MV, Evans WE: Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: Mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity. Mol Pharmacol 52:155, 1997
-
(1997)
Mol Pharmacol
, vol.52
, pp. 155
-
-
Galpin, A.J.1
Schuetz, J.D.2
Masson, E.3
Yanishevski, Y.4
Synold, T.W.5
Barredo, J.C.6
Pui, C.H.7
Relling, M.V.8
Evans, W.E.9
-
14
-
-
0028291535
-
Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia
-
Barredo JC, Synold TW, Laver J, Relling MV, Pui CH, Priest DG, Evans WE: Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia. Blood 84:564, 1994
-
(1994)
Blood
, vol.84
, pp. 564
-
-
Barredo, J.C.1
Synold, T.W.2
Laver, J.3
Relling, M.V.4
Pui, C.H.5
Priest, D.G.6
Evans, W.E.7
-
15
-
-
0028037401
-
Quantitative analysis of folylpolyglutamate synthetase gene expression in tumor tissues by the polymerase chain reaction: Marked variation of expression among leukemia patients
-
Lenz H-J, Danenberg K, Schnieders B, Goker E, Peters GJ, Garrow T, Shane B, Bertino JR, Danenberg PV: Quantitative analysis of folylpolyglutamate synthetase gene expression in tumor tissues by the polymerase chain reaction: Marked variation of expression among leukemia patients. Oncol Res 6:329, 1994
-
(1994)
Oncol Res
, vol.6
, pp. 329
-
-
Lenz, H.-J.1
Danenberg, K.2
Schnieders, B.3
Goker, E.4
Peters, G.J.5
Garrow, T.6
Shane, B.7
Bertino, J.R.8
Danenberg, P.V.9
-
16
-
-
0030831351
-
Disparate affinities of antifolates for folylpolyglutamate synthetase from human leukemia cells
-
Longo GS, Gorlick R, Tong WP, Ercikan E, Bertino JR: Disparate affinities of antifolates for folylpolyglutamate synthetase from human leukemia cells. Blood 90:1241, 1997
-
(1997)
Blood
, vol.90
, pp. 1241
-
-
Longo, G.S.1
Gorlick, R.2
Tong, W.P.3
Ercikan, E.4
Bertino, J.R.5
-
17
-
-
0001424078
-
Glutamyl hydrolase
-
Pfleider W, Rokos H (eds): Berlin, Blackwell Science
-
Galivan J, Yao R, Rhee M, Schneider E, Ryan T: Glutamyl hydrolase, in Pfleider W, Rokos H (eds): Chemistry and Biology of Pteridines and Folates. Berlin, Blackwell Science, 1997, p 439
-
(1997)
Chemistry and Biology of Pteridines and Folates
, pp. 439
-
-
Galivan, J.1
Yao, R.2
Rhee, M.3
Schneider, E.4
Ryan, T.5
-
18
-
-
0026653864
-
Intrinsic resistance to methotrexate in human soft tissue sarcoma cell lines
-
Li WW, Lin JT, Schweitzer BI, Tong WP, Niedwiecki D, Bertino JR: Intrinsic resistance to methotrexate in human soft tissue sarcoma cell lines. Cancer Res 52:3908, 1992
-
(1992)
Cancer Res
, vol.52
, pp. 3908
-
-
Li, W.W.1
Lin, J.T.2
Schweitzer, B.I.3
Tong, W.P.4
Niedwiecki, D.5
Bertino, J.R.6
-
19
-
-
0027378870
-
Increased activity of gamma-glutamyl hydrolase in human sarcoma cell lines: A novel mechanism of intrinsic resistance to methotrexate (MTX)
-
Li WW, Waltham M, Tong W, Schweitzer BI, Bertino JR: Increased activity of gamma-glutamyl hydrolase in human sarcoma cell lines: A novel mechanism of intrinsic resistance to methotrexate (MTX). Adv Exp Med Biol 338:635, 1993
-
(1993)
Adv Exp Med Biol
, vol.338
, pp. 635
-
-
Li, W.W.1
Waltham, M.2
Tong, W.3
Schweitzer, B.I.4
Bertino, J.R.5
-
20
-
-
0027222801
-
Acquisition of resistance to antifolates caused by enhanced gamma-glutamyl hydrolase activity
-
Rhee MS, Wang Y, Nair MG, Galivan J: Acquisition of resistance to antifolates caused by enhanced gamma-glutamyl hydrolase activity. Cancer Res 53:2227, 1993
-
(1993)
Cancer Res
, vol.53
, pp. 2227
-
-
Rhee, M.S.1
Wang, Y.2
Nair, M.G.3
Galivan, J.4
-
21
-
-
0028909247
-
Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM
-
Pizzorno G, Moroson BA, Cashmore AR, Russello O, Mayer JR, Galivan J, Bunni M, Priest D, Beardsley GP: Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM. Cancer Res 55:566, 1995
-
(1995)
Cancer Res
, vol.55
, pp. 566
-
-
Pizzorno, G.1
Moroson, B.A.2
Cashmore, A.R.3
Russello, O.4
Mayer, J.R.5
Galivan, J.6
Bunni, M.7
Priest, D.8
Beardsley, G.P.9
-
22
-
-
0030634067
-
Gamma-glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias
-
Longo GS, Gorlick R, Tong WP, Lin S, Steinherz P, Bertino JR: gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias. Oncol Res 9:259, 1997
-
(1997)
Oncol Res
, vol.9
, pp. 259
-
-
Longo, G.S.1
Gorlick, R.2
Tong, W.P.3
Lin, S.4
Steinherz, P.5
Bertino, J.R.6
-
23
-
-
0025201303
-
In vitro drug sensitivity of cells from children with leukemia using the MTT assay with improved culture conditions
-
Pieters R, Leonen AH, Huismans DR, Broekema GJ, Dirven MWJ, Heyenbrok MW, Hählen K, Veerman AJP: In vitro drug sensitivity of cells from children with leukemia using the MTT assay with improved culture conditions. Blood 76:2327, 1990
-
(1990)
Blood
, vol.76
, pp. 2327
-
-
Pieters, R.1
Leonen, A.H.2
Huismans, D.R.3
Broekema, G.J.4
Dirven, M.W.J.5
Heyenbrok, M.W.6
Hählen, K.7
Veerman, A.J.P.8
-
24
-
-
0028032922
-
Mononuclear cells contaminating acute lymphoblastic leukaemic samples tested for cellular drug resistance using the methyl-thiazol-tetrazolium assay
-
Kaspers GJL, Veerman AJP, Pieters R, Broekema GJ, Huismans DR, Kazemier KM, Loonen AH, Rottier MMA, Van Zantwijk CH, Hahlen K, Van Wering ER: Mononuclear cells contaminating acute lymphoblastic leukaemic samples tested for cellular drug resistance using the methyl-thiazol-tetrazolium assay. Br J Cancer 70:1047, 1994
-
(1994)
Br J Cancer
, vol.70
, pp. 1047
-
-
Kaspers, G.J.L.1
Veerman, A.J.P.2
Pieters, R.3
Broekema, G.J.4
Huismans, D.R.5
Kazemier, K.M.6
Loonen, A.H.7
Rottier, M.M.A.8
Van Zantwijk, C.H.9
Hahlen, K.10
Van Wering, E.R.11
-
25
-
-
0027144486
-
Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma
-
Braakhuis BJM, Jansen G, Noordhuis P, Kegel A, Peters GJ: Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma. Biochem Pharmacol 46:2155, 1993
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 2155
-
-
Braakhuis, B.J.M.1
Jansen, G.2
Noordhuis, P.3
Kegel, A.4
Peters, G.J.5
-
26
-
-
0008430894
-
Activity of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in clinical specimens of head and neck tumors
-
Pfleider W, Rokos H (eds): Berlin, Blackwell Scientific
-
Jansen G, Kathmann I, Peters GJ, Hordijk GJ, Slootweg PJ, Van Der Laan BFAM: Activity of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in clinical specimens of head and neck tumors, in Pfleider W, Rokos H (eds): Chemistry and Biology of Pteridines and Folates. Berlin, Blackwell Scientific, 1997, p 459
-
(1997)
Chemistry and Biology of Pteridines and Folates
, pp. 459
-
-
Jansen, G.1
Kathmann, I.2
Peters, G.J.3
Hordijk, G.J.4
Slootweg, P.J.5
Van Der Laan, B.F.A.M.6
-
27
-
-
0017184389
-
A rapid and sensitive method for the quantification of microgram quantities of protein utilising the principle of protein dye binding
-
Bradford MM: A rapid and sensitive method for the quantification of microgram quantities of protein utilising the principle of protein dye binding. Anal Biochem 72:248, 1976
-
(1976)
Anal Biochem
, vol.72
, pp. 248
-
-
Bradford, M.M.1
-
28
-
-
0026391210
-
Secretion of gamma-glutamyl hydrolase in vitro
-
O'Connor BM, Rotundo RF, Nimec Z, McGuire JJ, Galivan J: Secretion of gamma-glutamyl hydrolase in vitro. Cancer Res 51:3874, 1991
-
(1991)
Cancer Res
, vol.51
, pp. 3874
-
-
O'Connor, B.M.1
Rotundo, R.F.2
Nimec, Z.3
McGuire, J.J.4
Galivan, J.5
-
29
-
-
0030997685
-
Gamma-glutamyl hydrolase from human sarcoma HT-1080 cells: Characterization and inhibition by glutamine antagonists
-
Waltham MC, Li WW, Gritsman H, Tong WP, Bertino JR: gamma-Glutamyl hydrolase from human sarcoma HT-1080 cells: Characterization and inhibition by glutamine antagonists. Mol Pharmacol 51:825, 1997
-
(1997)
Mol Pharmacol
, vol.51
, pp. 825
-
-
Waltham, M.C.1
Li, W.W.2
Gritsman, H.3
Tong, W.P.4
Bertino, J.R.5
-
30
-
-
0032902787
-
Differential methotrexate resistance in childhood T-versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay
-
Rots MG, Pieters R, Kaspers GJL, Van Zantwijk CH, Noordhuis P, Mauritz R, Veerman AJP, Jansen G, Peters GJ: Differential methotrexate resistance in childhood T-versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay. Blood 93:1067, 1999
-
(1999)
Blood
, vol.93
, pp. 1067
-
-
Rots, M.G.1
Pieters, R.2
Kaspers, G.J.L.3
Van Zantwijk, C.H.4
Noordhuis, P.5
Mauritz, R.6
Veerman, A.J.P.7
Jansen, G.8
Peters, G.J.9
-
31
-
-
0026658557
-
Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (>50 chromosomes) B-lineage acute lymphoblastic leukemia
-
A Pediatric Oncology Group study
-
Whitehead VM, Vuchich MJ, Lauer SJ, Mahoney D, Carroll AJ, Shuster JJ, Esseltine DW, Payment C, Look AT, Akabutu J, Bowen T, Taylor LD, Camitta B, Pullen DJ: Accumulation of high levels of methotrexate polyglutamates in lymphoblasts from children with hyperdiploid (>50 chromosomes) B-lineage acute lymphoblastic leukemia: A Pediatric Oncology Group study. Blood 80:1316, 1992
-
(1992)
Blood
, vol.80
, pp. 1316
-
-
Whitehead, V.M.1
Vuchich, M.J.2
Lauer, S.J.3
Mahoney, D.4
Carroll, A.J.5
Shuster, J.J.6
Esseltine, D.W.7
Payment, C.8
Look, A.T.9
Akabutu, J.10
Bowen, T.11
Taylor, L.D.12
Camitta, B.13
Pullen, D.J.14
-
32
-
-
0028983176
-
Effects of gamma-glutamyl hydrolase on folyl and antifolylpolyglutamates in cultured H35 hepatoma cells
-
Yao R, Rhee MS, Galivan J: Effects of gamma-glutamyl hydrolase on folyl and antifolylpolyglutamates in cultured H35 hepatoma cells. Mol Pharmacol 48:505, 1995
-
(1995)
Mol Pharmacol
, vol.48
, pp. 505
-
-
Yao, R.1
Rhee, M.S.2
Galivan, J.3
-
33
-
-
0027438849
-
Mechanism-based approaches to inhibition of the synthesis and degradation of folate and antifolate polyglutamates
-
Kalman TI: Mechanism-based approaches to inhibition of the synthesis and degradation of folate and antifolate polyglutamates. Adv Exp Med Biol 338:639, 1993
-
(1993)
Adv Exp Med Biol
, vol.338
, pp. 639
-
-
Kalman, T.I.1
-
34
-
-
0026730653
-
Facilitated transport of methotrexate polyglutamates into lysosomes derived from S180 cells
-
Barrueco JR, O'Leary DF, Sirotnak FM: Facilitated transport of methotrexate polyglutamates into lysosomes derived from S180 cells. J Biol Chem 267:19986, 1992
-
(1992)
J Biol Chem
, vol.267
, pp. 19986
-
-
Barrueco, J.R.1
O'Leary, D.F.2
Sirotnak, F.M.3
-
35
-
-
0026651775
-
Metabolic turnover of methotrexate polyglutamates in lysosomes derived from S180 cells
-
Barrueco JR, O'Leary DF, Sirotnak FM: Metabolic turnover of methotrexate polyglutamates in lysosomes derived from S180 cells. J Biol Chem 267:15356, 1992
-
(1992)
J Biol Chem
, vol.267
, pp. 15356
-
-
Barrueco, J.R.1
O'Leary, D.F.2
Sirotnak, F.M.3
-
36
-
-
0029812829
-
Human gamma-glutamyl hydrolase: Cloning and characterization of the enzyme expressed in vitro
-
Yao R, Schneider E, Ryan TJ, Galivan J: Human gamma-glutamyl hydrolase: Cloning and characterization of the enzyme expressed in vitro. Proc Natl Acad Sci USA 93:10134, 1996
-
(1996)
Proc Natl Acad Sci Usa
, vol.93
, pp. 10134
-
-
Yao, R.1
Schneider, E.2
Ryan, T.J.3
Galivan, J.4
-
37
-
-
0003053562
-
Folylpolyglutamate hydrolase (FPGH) activity in human leukemia CCRF-CEM cells and blast cells from childhood leukemia patients
-
Pfleider W, Rokos H (eds): Berlin, Blackwell Science
-
Noordhuis P, Rots MG, Van Zantwijk CH, Pieters R, Veerman AJP, Peters GJ, Jansen G: Folylpolyglutamate hydrolase (FPGH) activity in human leukemia CCRF-CEM cells and blast cells from childhood leukemia patients, in Pfleider W, Rokos H (eds): Chemistry and Biology of Pteridines and Folates. Berlin, Blackwell Science, 1997, p 463
-
(1997)
Chemistry and Biology of Pteridines and Folates
, pp. 463
-
-
Noordhuis, P.1
Rots, M.G.2
Van Zantwijk, C.H.3
Pieters, R.4
Veerman, A.J.P.5
Peters, G.J.6
Jansen, G.7
-
38
-
-
0021838288
-
The cellular pharmacology of methotrexate
-
Goldman ID, Matherly LH: The cellular pharmacology of methotrexate. Pharmacol Ther 28:77, 1985
-
(1985)
Pharmacol Ther
, vol.28
, pp. 77
-
-
Goldman, I.D.1
Matherly, L.H.2
-
39
-
-
0345140633
-
Expression of mRNA encoding for the reduced folate carrier and folate metabolizing enzymes in childhood leukemia cells as measured with a competitive template RT-PCR method
-
abstr
-
Rots MG, Noordhuis P, Willey JC, Van Zantwijk CH, DeMuth JP, Veerman AJP, Pieters R, Peters GJ, Jansen G: Expression of mRNA encoding for the reduced folate carrier and folate metabolizing enzymes in childhood leukemia cells as measured with a competitive template RT-PCR method. Annals Oncol 9:162, 1998 (abstr)
-
(1998)
Annals Oncol
, vol.9
, pp. 162
-
-
Rots, M.G.1
Noordhuis, P.2
Willey, J.C.3
Van Zantwijk, C.H.4
Demuth, J.P.5
Veerman, A.J.P.6
Pieters, R.7
Peters, G.J.8
Jansen, G.9
-
40
-
-
0030948473
-
Defective transport is a common mechanism of acquired methotrexate resistance in acute lymphocytic leukemia and is associated with decreased reduced folate carrier expression
-
Gorlick R, Goker E, Trippett T, Steinherz P, Elisseyeff Y, Mazumdar M, Flintoff WF, Bertino JR: Defective transport is a common mechanism of acquired methotrexate resistance in acute lymphocytic leukemia and is associated with decreased reduced folate carrier expression. Blood 89:1013, 1997
-
(1997)
Blood
, vol.89
, pp. 1013
-
-
Gorlick, R.1
Goker, E.2
Trippett, T.3
Steinherz, P.4
Elisseyeff, Y.5
Mazumdar, M.6
Flintoff, W.F.7
Bertino, J.R.8
-
41
-
-
0002001872
-
Resistance to antimetabolites
-
Schilsky RL, Milano GA, Ratin MJ (eds): New York, NY, Dekker
-
Peters GJ, Jansen G: Resistance to antimetabolites, in Schilsky RL, Milano GA, Ratin MJ (eds): Principles of Antineoplastic Drug Development and Pharmacology. New York, NY, Dekker, 1996, p 543
-
(1996)
Principles of Antineoplastic Drug Development and Pharmacology
, pp. 543
-
-
Peters, G.J.1
Jansen, G.2
-
42
-
-
0030889437
-
Everything you always wanted to know about cellular drug resistance in childhood acute lymphoblastic leukemia
-
Pieters R, Klumper E, Kaspers GJL, Veerman AJP: Everything you always wanted to know about cellular drug resistance in childhood acute lymphoblastic leukemia. Crit Rev Oncol Hematol 25:11, 1997
-
(1997)
Crit Rev Oncol Hematol
, vol.25
, pp. 11
-
-
Pieters, R.1
Klumper, E.2
Kaspers, G.J.L.3
Veerman, A.J.P.4
-
43
-
-
0002014333
-
The role of impaired transport in (pre)clinical resistance to methotrexate: Insights on new antifolates
-
Jansen G, Pieters R: The role of impaired transport in (pre)clinical resistance to methotrexate: Insights on new antifolates. Drug Res Updates 1:211, 1998
-
(1998)
Drug Res Updates
, vol.1
, pp. 211
-
-
Jansen, G.1
Pieters, R.2
-
44
-
-
0029846176
-
Intrinsic and acquired resistance to methotrexate in acute leukemia
-
Gorlick R, Goker E, Trippett T, Waltham M, Banerjee D, Bertino JR: Intrinsic and acquired resistance to methotrexate in acute leukemia. N Engl J Med 335:1041, 1996
-
(1996)
N Engl J Med
, vol.335
, pp. 1041
-
-
Gorlick, R.1
Goker, E.2
Trippett, T.3
Waltham, M.4
Banerjee, D.5
Bertino, J.R.6
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