Should adolescents with acute lymphoblastic leukemia be treated as old children or young adults? Comparison of the French FRALLE-93 and LALA-94 trials

Journal of Clinical Oncology

Volumn 21, Issue 5, 2003, Pages 774-780

  Boissel, Nicolas ^b   Auclerc, Marie Françoise ^b   Lhéritier, Véronique ^b   Perel, Yves ^b   Thomas, Xavier ^b   Leblanc, Thierry ^b   Rousselot, Philippe ^b   Cayuela, Jean Michel ^b   Gabert, Jean ^b   Fegueux, Nathalie ^b   Piguet, Christophe ^b   Huguet Rigal, Françoise ^b   Berthou, Christian ^b   Boiron, Jean Michel ^b   Pautas, Cécile ^b   Michel, Gérard ^b   Fière, Denis ^b   Leverger, Guy ^b   Dombret, Hervé ^b   Baruchel, André ^a  

^a SAINT LOUIS HOSPITAL   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; ANTINEOPLASTIC AGENT; MEMBRANE METALLOENDOPEPTIDASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; B LYMPHOCYTE; CANCER THERAPY; CELL LINEAGE; CONTROLLED STUDY; CYTOGENETICS; DISEASE FREE SURVIVAL; HIGH RISK PATIENT; HUMAN; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MEDICAL PRACTICE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; REMISSION; RETROSPECTIVE STUDY; T LYMPHOCYTE; TREATMENT OUTCOME; UNIVARIATE ANALYSIS; ACUTE LYMPHOCYTIC LEUKEMIA; CHROMOSOME ANALYSIS; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; FEMALE; FRANCE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; MALE; METABOLISM; MORTALITY; MULTIMODALITY CANCER THERAPY; NOTE; PATHOLOGY; PLOIDY; RADIOTHERAPY; RANDOMIZED CONTROLLED TRIAL; SURVIVAL RATE;

ADOLESCENT; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CELL LINEAGE; COMBINED MODALITY THERAPY; CYTOGENETIC ANALYSIS; DISEASE-FREE SURVIVAL; FEMALE; FRANCE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKOCYTE COUNT; MALE; NEPRILYSIN; PLOIDIES; PROGNOSIS; RADIOTHERAPY; REMISSION INDUCTION; RETROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 0037362950     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2003.02.053     Document Type: Article

References (30)

1. Schrappe M, Reiter A, Ludwig WD, et al: Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: Results of trial ALL-BFM 90. German-Austrian-Swiss ALL-BFM Study Group. Blood 95:3310-3322, 2000
2. Silverman LB, Gelber RD, Dalton VK, et al: Improved outcome for children with acute lymphoblastic leukemia: Results of Dana-Farber Consortium Protocol 91-01. Blood 97:1211-1218, 2001
3. Sebban C, Lepage E, Vernant JP, et al: Allogeneic bone marrow transplantation in adult acute lymphoblastic leukemia in first complete remission: A comparative study. French Group of Therapy of Adult Acute Lymphoblastic Leukemia. J Clin Oncol 12:2580-2587, 1994
4. Hoelzer D, Gokbuget N. New approaches to acute lymphoblastic leukemia in adults: Where do we go? Semin Oncol 27:540-559, 2000
5. Kantarjian HM, O'Brien S, Smith TL, et al: Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia. J Clin Oncol 18:547-561, 2000
6. Boucheix C, David B, Sebban C, et al: Immunophenotype of adult acute lymphoblastic leukemia, clinical parameters, and outcome: An analysis of a prospective trial including 562 tested patients (LALA87). French Group on Therapy for Adult Acute Lymphoblastic Leukemia. Blood 84:1603-1612, 1994
7. Uckun FM, Reaman G, Steinherez PG, et al: Improved clinical outcome for children with T-lineage acute lymphoblastic leukemia after contemporary chemotherapy: A Children's Cancer Group Study. Leuk Lymphoma 24:57-70, 1996
8. Put CH, Evans WE. Acute lymphoblastic leukemia. N Engl J Med 339:605-615, 1998
9. Maung ZT, Reid MM, Matheson E, et al: Corticosteroid resistance is increased in lymphoblasts from adults compared with children: Preliminary results of in vitro drug sensitivity study in adults with acute Iymphoblastic leukaemia. Br J Haematol 91:93-100, 1995
10. Styczynski J, Pieters R, Huismans DR, et al: In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia. Br J Haematol 110:813-818, 2000
11. Bene MC, Castoldi G, Knapp W, et al: Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL). Leukemia 9:1783-1786, 1995
12. Michel G, Landman-Parker J, Auclerc MF, et al: Use of recombinant human granulocyte colony-stimulating factor to increase chemotherapy dose-intensity: a randomized trial in very high- risk childhood acute lymphoblastic leukemia. J Clin Oncol 18:1517-1524, 2000
13. van Dongen JJ, Macintyre EA, Gabert JA, et al: Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted Action: Investigation of minimal residual disease in acute leukemia. Leukemia 13:1901-1928, 1999
14. Raynaud S, Mauvieux L, Cayuela JM, et al: TEL/AML1 fusion gene is a rare event in adult acute lymphoblastic leukemia. Leukemia 10:1529-1530, 1996
15. Cayuela JM, Baruchel A, Orange C, et al: TEL-AML1 fusion RNA as a new target to detect minimal residual disease in pediatric B-cell precursor acute lymphoblastic leukemia. Blood 88:302-308, 1996
16. Kaplan E, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
17. Peto R, Peto J: Asymptotically efficient rank invariant test procedures. J R Stat Soc 135:185-206, 1972
18. Cox D: Regression models and life-tables. J R Stat Soc 34:187-220, 1972
19. Fiere D, Schaison G, Bancillon A, et al: What is the best treatment for patients between 15 years and 20 years with acute lymphoblastic leukemia. Comparative results of two protocols, one for adults, one for children. Blood 76:270a, 1990
20. Stock W, Sather H, Dodge RK, et al: Outcome of adolescents and young adults with ALL: A comparison of Children's Cancer Group (CCG) and Cancer and Leukemia Group B (CALGB) regimens. Blood 96:467a, 2000
21. Chessells JM, Hall E, Prentice HG, et al: The impact of age on outcome in lymphoblastic leukaemia; MRC UKALL X and XA compared: A report from the MRC Paediatric and Adult Working Parties. Leukemia 12:463-473, 1998
22. Secker-Walker LM, Craig JM, Hawkins JM, et al: Philadelphia positive acute lymphoblastic leukemia in adults: Age distribution, BCR breakpoint and prognostic significance. Leukemia 5:196-199, 1991
23. Borkhardt A, Cazzaniga G, Viehmann S, et al: Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials. Associazione Italiana Ematologia Oncologia Pediatrica and the Berlin-Frankfurt-Munster Study Group. Blood 90:571-577, 1997
24. Nachman J, Sather HN, Buckley JD, et al: Young adults 16-21 years of age at diagnosis entered on Children's Cancer Group acute lymphoblastic leukemia and acute myeloblastic leukemia protocols. Results of treatment. Cancer 71:3377-3385, 1993
25. Leikin SL, Brubaker C, Hartmann JR, et al: Varying prednisone dosage in remission induction of previously untreated childhood leukemia. Cancer 21:346-351, 1968
26. Schwartz CL, Thompson EB, Gelber RD, et al: Improved response with higher corticosteroid dose in children with acute lymphoblastic leukemia. J Clin Oncol 19:1040-1046, 2001
27. Amylon MD, Shuster J, Pullen J, et al: Intensive high-dose asparaginase consolidation improves survival for pediatric patients with T cell acute lymphoblastic leukemia and advanced stage lymphoblastic lymphoma: A Pediatric Oncology Group study. Leukemia 13:335-342, 1999
28. Riehm H, Gadner H, Henze G, et al: Results and significance of six randomized trials in four consecutive ALL-BFM studies. Hamatol Bluttransfus 33:439-450, 1990
29. Tubergen DG, Gilchrist GS, O'Brien RT, et al: Improved outcome with delayed intensification for children with acute lymphoblastic leukemia and intermediate presenting features: A Children's Cancer Group phase III trial. J Clin Oncol 11:527-537, 1993
30. Nachman JB, Sather HN, Sensel MG, et al: Augmented post-induction therapy for children with high-risk acute lymphoblastic leukemia and a slow response to initial therapy. N Engl J Med 338:1663-1671, 1998