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Volumn 6, Issue 276, 2013, Pages

Eukaryotic G protein signaling evolved to require G protein-coupled receptors for activation

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN;

EID: 84878294989     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2003768     Document Type: Article
Times cited : (64)

References (47)
  • 1
    • 0023062991 scopus 로고
    • G proteins: Transducers of receptor-generated signals
    • A. G. Gilman, G proteins: Transducers of receptor-generated signals. Annu. Rev. Biochem. 56, 615-649 (1987).
    • (1987) Annu. Rev. Biochem. , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 2
    • 0030920782 scopus 로고    scopus 로고
    • G protein mechanisms: Insights from structural analysis
    • S. R. Sprang, G protein mechanisms: Insights from structural analysis. Annu. Rev. Biochem. 66, 639-678 (1997).
    • (1997) Annu. Rev. Biochem. , vol.66 , pp. 639-678
    • Sprang, S.R.1
  • 3
    • 84860799284 scopus 로고    scopus 로고
    • Differences in intradomain and interdomain motion confer distinct activation properties to structurally similar Gα proteins
    • J. C. Jones, A. M. Jones, B. R. Temple, H. G. Dohlman, Differences in intradomain and interdomain motion confer distinct activation properties to structurally similar Gα proteins. Proc. Natl. Acad. Sci. U.S.A. 109, 7275-7279 (2012).
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 7275-7279
    • Jones, J.C.1    Jones, A.M.2    Temple, B.R.3    Dohlman, H.G.4
  • 4
    • 79851474025 scopus 로고    scopus 로고
    • The crystal structure of a self-activating G protein α subunit reveals its distinct mechanism of signal initiation
    • J. C. Jones, J. W. Duffy, M. Machius, B. R. Temple, H. G. Dohlman, A. M. Jones, The crystal structure of a self-activating G protein α subunit reveals its distinct mechanism of signal initiation. Sci. Signal. 4, ra8 (2011).
    • (2011) Sci. Signal. , vol.4
    • Jones, J.C.1    Duffy, J.W.2    Machius, M.3    Temple, B.R.4    Dohlman, H.G.5    Jones, A.M.6
  • 5
    • 0022876166 scopus 로고
    • The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
    • K. M. Ferguson, T. Higashijima, M. D. Smigel, A. G. Gilman, The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins. J. Biol. Chem. 261, 7393-7399 (1986).
    • (1986) J. Biol. Chem. , vol.261 , pp. 7393-7399
    • Ferguson, K.M.1    Higashijima, T.2    Smigel, M.D.3    Gilman, A.G.4
  • 8
    • 79953867248 scopus 로고    scopus 로고
    • Functional reconstitution of an atypical G protein heterotrimer and regulator of G protein signaling protein (RGS1) from Arabidopsis thaliana
    • J. C. Jones, B. R. S. Temple, A. M. Jones, H. G. Dohlman, Functional reconstitution of an atypical G protein heterotrimer and regulator of G protein signaling protein (RGS1) from Arabidopsis thaliana. J. Biol. Chem. 286, 13143-13150 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 13143-13150
    • Jones, J.C.1    Temple, B.R.S.2    Jones, A.M.3    Dohlman, H.G.4
  • 10
    • 84867098172 scopus 로고    scopus 로고
    • Endocytosis of the seven-transmembrane RGS1 protein activates G-protein-coupled signalling in Arabidopsis
    • D. Urano, N. Phan, J. C. Jones, J. Yang, J. Huang, J. Grigston, J. P. Taylor, A. M. Jones, Endocytosis of the seven-transmembrane RGS1 protein activates G-protein-coupled signalling in Arabidopsis. Nat. Cell Biol. 14, 1079-1088 (2012).
    • (2012) Nat. Cell Biol. , vol.14 , pp. 1079-1088
    • Urano, D.1    Phan, N.2    Jones, J.C.3    Yang, J.4    Huang, J.5    Grigston, J.6    Taylor, J.P.7    Jones, A.M.8
  • 11
    • 77958598376 scopus 로고    scopus 로고
    • Glucose attenuation of auxinmediated bimodality in lateral root formation is partly coupled by the heterotrimeric G protein complex
    • K. S. Booker, J. Schwarz, M. B. Garrett, A. M. Jones, Glucose attenuation of auxinmediated bimodality in lateral root formation is partly coupled by the heterotrimeric G protein complex. PLoS One 5, e12833 (2010).
    • (2010) PLoS One , vol.5
    • Booker, K.S.1    Schwarz, J.2    Garrett, M.B.3    Jones, A.M.4
  • 12
    • 79960671811 scopus 로고    scopus 로고
    • Regulators of G-protein signaling and their Gα substrates: Promises and challenges in their use as drug discovery targets
    • A. J. Kimple, D. E. Bosch, P. M. Giguere, D. P. Siderovski, Regulators of G-protein signaling and their Gα substrates: Promises and challenges in their use as drug discovery targets. Pharmacol. Rev. 63, 728-749 (2011).
    • (2011) Pharmacol. Rev. , vol.63 , pp. 728-749
    • Kimple, A.J.1    Bosch, D.E.2    Giguere, P.M.3    Siderovski, D.P.4
  • 13
    • 0036193842 scopus 로고    scopus 로고
    • G proteins and pheromone signaling
    • H. G. Dohlman, G proteins and pheromone signaling. Annu. Rev. Physiol. 64, 129-152 (2002).
    • (2002) Annu. Rev. Physiol. , vol.64 , pp. 129-152
    • Dohlman, H.G.1
  • 15
    • 62649113993 scopus 로고    scopus 로고
    • Phylogenomic analyses support the monophyly of Excavata and resolve relationships among eukaryotic "supergroups "
    • V. Hampl, L. Hug, J. W. Leigh, J. B. Dacks, B. F. Lang, A. G. Simpson, A. J. Roger, Phylogenomic analyses support the monophyly of Excavata and resolve relationships among eukaryotic "supergroups " . Proc. Natl. Acad. Sci. U.S.A. 106, 3859-3864 (2009).
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 3859-3864
    • Hampl, V.1    Hug, L.2    Leigh, J.W.3    Dacks, J.B.4    Lang, B.F.5    Simpson, A.G.6    Roger, A.J.7
  • 16
    • 77954090275 scopus 로고    scopus 로고
    • Kingdoms Protozoa and Chromista and the eozoan root of the eukaryotic tree
    • T. Cavalier-Smith, Kingdoms Protozoa and Chromista and the eozoan root of the eukaryotic tree. Biol. Lett. 6, 342-345 (2010).
    • (2010) Biol. Lett. , vol.6 , pp. 342-345
    • Cavalier-Smith, T.1
  • 17
    • 84855402621 scopus 로고    scopus 로고
    • The origin of GPCRs: Identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi
    • A. Krishnan, M. S. Almen, R. Fredriksson, H. B. Schioth, The origin of GPCRs: Identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi. PLoS One 7, e29817 (2012).
    • (2012) PLoS One , vol.7
    • Krishnan, A.1    Almen, M.S.2    Fredriksson, R.3    Schioth, H.B.4
  • 18
    • 79952697352 scopus 로고    scopus 로고
    • Comparative genomics uncovers novel structural and functional features of the heterotrimeric GTPase signaling system
    • V. Anantharaman, S. Abhiman, R. F. de Souza, L. Aravind, Comparative genomics uncovers novel structural and functional features of the heterotrimeric GTPase signaling system. Gene 475, 63-78 (2011).
    • (2011) Gene , vol.475 , pp. 63-78
    • Anantharaman, V.1    Abhiman, S.2    De Souza, R.F.3    Aravind, L.4
  • 20
    • 0031826040 scopus 로고    scopus 로고
    • SOSUI: Classification and secondary structure prediction system for membrane proteins
    • T. Hirokawa, S. Boon-Chieng, S. Mitaku, SOSUI: Classification and secondary structure prediction system for membrane proteins. Bioinformatics 14, 378-379 (1998).
    • (1998) Bioinformatics , vol.14 , pp. 378-379
    • Hirokawa, T.1    Boon-Chieng, S.2    Mitaku, S.3
  • 21
    • 84855881484 scopus 로고    scopus 로고
    • Phylogenetic relationships within the Opisthokonta based on phylogenomic analyses of conserved single-copy protein domains
    • G. Torruella, R. Derelle, J. Paps, B. F. Lang, A. J. Roger, K. Shalchian-Tabrizi, I. Ruiz-Trillo, Phylogenetic relationships within the Opisthokonta based on phylogenomic analyses of conserved single-copy protein domains. Mol. Biol. Evol. 29, 531-544 (2012).
    • (2012) Mol. Biol. Evol. , vol.29 , pp. 531-544
    • Torruella, G.1    Derelle, R.2    Paps, J.3    Lang, B.F.4    Roger, A.J.5    Shalchian-Tabrizi, K.6    Ruiz-Trillo, I.7
  • 23
    • 0027132717 scopus 로고
    • The 2.2 Å crystal structure of transducin-a complexed with GTPγS
    • J. P. Noel, H. E. Hamm, P. B. Sigler, The 2.2 Å crystal structure of transducin-a complexed with GTPγS. Nature 366, 654-663 (1993).
    • (1993) Nature , vol.366 , pp. 654-663
    • Noel, J.P.1    Hamm, H.E.2    Sigler, P.B.3
  • 26
    • 4544338193 scopus 로고    scopus 로고
    • Perturbing the linker regions of the a-subunit of transducin: A new class of constitutively active GTP-binding proteins
    • S. Majumdar, S. Ramachandran, R. A. Cerione, Perturbing the linker regions of the a-subunit of transducin: A new class of constitutively active GTP-binding proteins. J. Biol. Chem. 279, 40137-40145 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 40137-40145
    • Majumdar, S.1    Ramachandran, S.2    Cerione, R.A.3
  • 27
    • 0346755948 scopus 로고    scopus 로고
    • Rapid activation of transducin by mutations distant from the nucleotide-binding site: Evidence for a mechanistic model of receptorcatalyzed nucleotide exchange by G proteins
    • E. P. Marin, A. G. Krishna, T. P. Sakmar, Rapid activation of transducin by mutations distant from the nucleotide-binding site: Evidence for a mechanistic model of receptorcatalyzed nucleotide exchange by G proteins. J. Biol. Chem. 276, 27400-27405 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 27400-27405
    • Marin, E.P.1    Krishna, A.G.2    Sakmar, T.P.3
  • 28
    • 0027956207 scopus 로고
    • Rapid GDP release from Gsα in patients with gain and loss of endocrine function
    • T. Iiri, P. Herzmark, J. M. Nakamoto, C. van Dop, H. R. Bourne, Rapid GDP release from Gsα in patients with gain and loss of endocrine function. Nature 371, 164-168 (1994).
    • (1994) Nature , vol.371 , pp. 164-168
    • Iiri, T.1    Herzmark, P.2    Nakamoto, J.M.3    Van Dop, C.4    Bourne, H.R.5
  • 30
    • 27144525489 scopus 로고    scopus 로고
    • New roles for Ga and RGS proteins: Communication continues despite pulling sisters apart
    • T. M. Wilkie, L. Kinch, New roles for Ga and RGS proteins: Communication continues despite pulling sisters apart. Curr. Biol. 15, R843-R854 (2005).
    • (2005) Curr. Biol. , vol.15
    • Wilkie, T.M.1    Kinch, L.2
  • 31
    • 80052158550 scopus 로고    scopus 로고
    • Independent HHsearch, Needleman-Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families
    • K. J. Nordström, M. Sällman Almén, M. M. Edstam, R. Fredriksson, H. B. Schiöth, Independent HHsearch, Needleman-Wunsch-based, and motif analyses reveal the overall hierarchy for most of the G protein-coupled receptor families. Mol. Biol. Evol. 28, 2471-2480 (2011).
    • (2011) Mol. Biol. Evol. , vol.28 , pp. 2471-2480
    • Nordström, K.J.1    Sällman Almén, M.2    Edstam, M.M.3    Fredriksson, R.4    Schiöth, H.B.5
  • 33
    • 79957620875 scopus 로고    scopus 로고
    • Ric-8B is a GTP-dependent G protein as guanine nucleotide exchange factor
    • P. Chan, M. Gabay, F. A. Wright, G. G. Tall, Ric-8B is a GTP-dependent G protein as guanine nucleotide exchange factor. J. Biol. Chem. 286, 19932-19942 (2011).
    • (2011) J. Biol. Chem. , vol.286 , pp. 19932-19942
    • Chan, P.1    Gabay, M.2    Wright, F.A.3    Tall, G.G.4
  • 34
    • 0037424298 scopus 로고    scopus 로고
    • Mammalian Ric-8A (synembryn) is a heterotrimeric Gα protein guanine nucleotide exchange factor
    • G. G. Tall, A. M. Krumins, A. G. Gilman, Mammalian Ric-8A (synembryn) is a heterotrimeric Gα protein guanine nucleotide exchange factor. J. Biol. Chem. 278, 8356-8362 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 8356-8362
    • Tall, G.G.1    Krumins, A.M.2    Gilman, A.G.3
  • 36
    • 27944474033 scopus 로고    scopus 로고
    • Selectionism and neutralism in molecular evolution
    • M. Nei, Selectionism and neutralism in molecular evolution. Mol. Biol. Evol. 22, 2318-2342 (2005).
    • (2005) Mol. Biol. Evol. , vol.22 , pp. 2318-2342
    • Nei, M.1
  • 37
    • 0032492722 scopus 로고    scopus 로고
    • Sst2 is a GTPase-activating protein for Gpa1: Purification and characterization of a cognate RGS-Gα protein pair in yeast
    • D. M. Apanovitch, K. C. Slep, P. B. Sigler, H. G. Dohlman, Sst2 is a GTPase-activating protein for Gpa1: Purification and characterization of a cognate RGS-Gα protein pair in yeast. Biochemistry 37, 4815-4822 (1998).
    • (1998) Biochemistry , vol.37 , pp. 4815-4822
    • Apanovitch, D.M.1    Slep, K.C.2    Sigler, P.B.3    Dohlman, H.G.4
  • 38
    • 75749110963 scopus 로고    scopus 로고
    • Metronidazole is still the drug of choice for treatment of anaerobic infections
    • S. Lofmark, C. Edlund, C. E. Nord, Metronidazole is still the drug of choice for treatment of anaerobic infections. Clin. Infect. Dis. 50 (suppl. 1), S16-S23 (2010).
    • (2010) Clin. Infect. Dis. , vol.50 , Issue.SUPPL. 1
    • Lofmark, S.1    Edlund, C.2    Nord, C.E.3
  • 39
    • 0020347032 scopus 로고
    • Primary amebic meningoencephalitis and the biology of Naegleria fowleri
    • D. T. John, Primary amebic meningoencephalitis and the biology of Naegleria fowleri. Annu. Rev. Microbiol. 36, 101-123 (1982).
    • (1982) Annu. Rev. Microbiol. , vol.36 , pp. 101-123
    • John, D.T.1
  • 40
    • 79957613599 scopus 로고    scopus 로고
    • MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods
    • K. Tamura, D. Peterson, N. Peterson, G. Stecher, M. Nei, S. Kumar, MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 28, 2731-2739 (2011).
    • (2011) Mol. Biol. Evol. , vol.28 , pp. 2731-2739
    • Tamura, K.1    Peterson, D.2    Peterson, N.3    Stecher, G.4    Nei, M.5    Kumar, S.6
  • 41
    • 30744470609 scopus 로고    scopus 로고
    • Application of phylogenetic networks in evolutionary studies
    • D. H. Huson, D. Bryant, Application of phylogenetic networks in evolutionary studies. Mol. Biol. Evol. 23, 254-267 (2006).
    • (2006) Mol. Biol. Evol. , vol.23 , pp. 254-267
    • Huson, D.H.1    Bryant, D.2
  • 42
    • 0021993452 scopus 로고
    • s. Accumulation and turnover of enzyme-nucleotide intermediates
    • s. Accumulation and turnover of enzyme-nucleotide intermediates. J. Biol. Chem. 260, 266-272 (1985).
    • (1985) J. Biol. Chem. , vol.260 , pp. 266-272
    • Brandt, D.R.1    Ross, E.M.2
  • 43
    • 32944462411 scopus 로고    scopus 로고
    • Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae
    • S. A. Chasse, P. Flanary, S. C. Parnell, N. Hao, J. Y. Cha, D. P. Siderovski, H. G. Dohlman, Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae. Eukaryot. Cell 5, 330-346 (2006).
    • (2006) Eukaryot. Cell , vol.5 , pp. 330-346
    • Chasse, S.A.1    Flanary, P.2    Parnell, S.C.3    Hao, N.4    Cha, J.Y.5    Siderovski, D.P.6    Dohlman, H.G.7
  • 45
    • 33748253906 scopus 로고    scopus 로고
    • The Dictyostelium repertoire of seven transmembrane domain receptors
    • Y. Prabhu, L. Eichinger, The Dictyostelium repertoire of seven transmembrane domain receptors. Eur. J. Cell Biol. 85, 937-946 (2006).
    • (2006) Eur. J. Cell Biol. , vol.85 , pp. 937-946
    • Prabhu, Y.1    Eichinger, L.2
  • 46
    • 0025834532 scopus 로고
    • Diversity of G proteins in signal transduction
    • M. I. Simon, M. P. Strathmann, N. Gautam, Diversity of G proteins in signal transduction. Science 252, 802-808 (1991).
    • (1991) Science , vol.252 , pp. 802-808
    • Simon, M.I.1    Strathmann, M.P.2    Gautam, N.3
  • 47
    • 78349234247 scopus 로고    scopus 로고
    • Evolution of a signaling nexus constrained by protein interfaces and conformational states
    • B. R. Temple, C. D. Jones, A. M. Jones, Evolution of a signaling nexus constrained by protein interfaces and conformational states. PLoS Comput. Biol. 6, e1000962 (2010).
    • (2010) PLoS Comput. Biol. , vol.6
    • Temple, B.R.1    Jones, C.D.2    Jones, A.M.3


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