-
1
-
-
78751661556
-
Evolution of Human BCR-ABL1 Lymphoblastic Leukaemia-Initiating Cells
-
Notta, F.; Mullighan, C. G.; Wang, J. C.; Poeppl, A.; Doulatov, S.; Phillips, L. A.; Ma, J.; Minden, M. D.; Downing, J. R.; Dick, J. E. Evolution of Human BCR-ABL1 Lymphoblastic Leukaemia-Initiating Cells. Nature 2011, 469, 362-367.
-
(2011)
Nature
, vol.469
, pp. 362-367
-
-
Notta, F.1
Mullighan, C.G.2
Wang, J.C.3
Poeppl, A.4
Doulatov, S.5
Phillips, L.A.6
Ma, J.7
Minden, M.D.8
Downing, J.R.9
Dick, J.E.10
-
2
-
-
0035499267
-
Stem Cells, Cancer, and Cancer Stem Cells
-
Reya, T.; Morrison, S. J.; Clarke, M. F.; Weissman, I. L. Stem Cells, Cancer, and Cancer Stem Cells. Nature 2001, 414, 105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
3
-
-
60649110684
-
Cancer Stem Cells in Solid Tumors: An Overview
-
O'Brien, C. A.; Kreso, A.; Dick, J. E. Cancer Stem Cells in Solid Tumors: An Overview. Semin. Radiat. Oncol. 2009, 19, 71-77.
-
(2009)
Semin. Radiat. Oncol
, vol.19
, pp. 71-77
-
-
O'Brien, C.A.1
Kreso, A.2
Dick, J.E.3
-
4
-
-
78249250559
-
Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients That Is Reversible and Not Hierarchically Organized
-
Quintana, E.; Shackleton, M.; Foster, H. R.; Fullen, D. R.; Sabel, M. S.; Johnson, T. M.; Morrison, S. J. Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients That Is Reversible and Not Hierarchically Organized. Cancer Cell 2010, 18, 510-523.
-
(2010)
Cancer Cell
, vol.18
, pp. 510-523
-
-
Quintana, E.1
Shackleton, M.2
Foster, H.R.3
Fullen, D.R.4
Sabel, M.S.5
Johnson, T.M.6
Morrison, S.J.7
-
5
-
-
0037388204
-
Prospective Identification of Tumorigenic Breast Cancer Cells
-
Al-Hajj, M.; Wicha, M. S.; Benito-Hernandez, A.; Morrison, S. J.; Clarke, M. F. Prospective Identification of Tumorigenic Breast Cancer Cells. Proc. Natl. Acad. Sci. U. S. A. 2003, 100, 3983-3988.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
6
-
-
49149107236
-
Colorectal Cancer Stem Cells Are Enriched in Xenogeneic Tumors following Chemotherapy
-
Dylla, S. J.; Beviglia, L.; Park, I. K.; Chartier, C.; Raval, J.; Ngan, L.; Pickell, K.; Aguilar, J.; Lazetic, S.; Smith-Berdan, S.; et al. Colorectal Cancer Stem Cells Are Enriched in Xenogeneic Tumors following Chemotherapy. PLoS One 2008, 3, e2428.
-
(2008)
PLoS One
, vol.3
-
-
Dylla, S.J.1
Beviglia, L.2
Park, I.K.3
Chartier, C.4
Raval, J.5
Ngan, L.6
Pickell, K.7
Aguilar, J.8
Lazetic, S.9
Smith-Berdan, S.10
-
7
-
-
80052031109
-
Human Hepatic Cancer Stem Cells Are Characterized by Common Stemness Traits and Diverse Oncogenic Pathways
-
Marquardt, J. U.; Raggi, C.; Andersen, J. B.; Seo, D.; Avital, I.; Geller, D.; Lee, Y. H.; Kitade, M.; Holczbauer, A.; Gillen, M. C.; et al. Human Hepatic Cancer Stem Cells Are Characterized by Common Stemness Traits and Diverse Oncogenic Pathways. Hepatology 2011, 54, 1031-1042.
-
(2011)
Hepatology
, vol.54
, pp. 1031-1042
-
-
Marquardt, J.U.1
Raggi, C.2
Andersen, J.B.3
Seo, D.4
Avital, I.5
Geller, D.6
Lee, Y.H.7
Kitade, M.8
Holczbauer, A.9
Gillen, M.C.10
-
8
-
-
33745924696
-
Side Population Purified from Hepatocellular Carcinoma Cells Harbors Cancer Stem Cell-Like Properties
-
Chiba, T.; Kita, K.; Zheng, Y. W.; Yokosuka, O.; Saisho, H.; Iwama, A.; Nakauchi, H.; Taniguchi, H. Side Population Purified from Hepatocellular Carcinoma Cells Harbors Cancer Stem Cell-Like Properties. Hepatology 2006, 44, 240-251.
-
(2006)
Hepatology
, vol.44
, pp. 240-251
-
-
Chiba, T.1
Kita, K.2
Zheng, Y.W.3
Yokosuka, O.4
Saisho, H.5
Iwama, A.6
Nakauchi, H.7
Taniguchi, H.8
-
9
-
-
79956351015
-
Normal and Neoplastic Nonstem Cells Can Spontaneously Convert to a Stem-Like State
-
Chaffer, C. L.; Brueckmann, I.; Scheel, C.; Kaestli, A. J.; Wiggins, P. A.; Rodrigues, L. O.; Brooks, M.; Reinhardt, F.; Su, Y.; Polyak, K.; et al. Normal and Neoplastic Nonstem Cells Can Spontaneously Convert to a Stem-Like State. Proc. Natl. Acad. Sci. U. S. A. 2011, 108, 7950-7955.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A
, vol.108
, pp. 7950-7955
-
-
Chaffer, C.L.1
Brueckmann, I.2
Scheel, C.3
Kaestli, A.J.4
Wiggins, P.A.5
Rodrigues, L.O.6
Brooks, M.7
Reinhardt, F.8
Su, Y.9
Polyak, K.10
-
10
-
-
22244433866
-
Side Population Is Enriched in Tumorigenic, Stem-Like Cancer Cells, Whereas ABCG2+ and ABCG2-Cancer Cells Are Similarly Tumorigenic
-
Patrawala, L.; Calhoun, T.; Schneider-Broussard, R.; Zhou, J.; Claypool, K.; Tang, D. G. Side Population Is Enriched in Tumorigenic, Stem-Like Cancer Cells, Whereas ABCG2+ and ABCG2-Cancer Cells Are Similarly Tumorigenic. Cancer Res. 2005, 65, 6207-6219.
-
(2005)
Cancer Res
, vol.65
, pp. 6207-6219
-
-
Patrawala, L.1
Calhoun, T.2
Schneider-Broussard, R.3
Zhou, J.4
Claypool, K.5
Tang, D.G.6
-
11
-
-
84867212473
-
Oncogene-Specific Formation of Chemoresistant Murine Hepatic Cancer Stem Cells
-
Apr 13. [Epub ahead of print]
-
Chow, E. K.; Fan, L. L.; Chen, X.; Bishop, J. M. Oncogene-Specific Formation of Chemoresistant Murine Hepatic Cancer Stem Cells. Hepatology 2012, Apr 13. [Epub ahead of print]
-
(2012)
Hepatology
-
-
Chow, E.K.1
Fan, L.L.2
Chen, X.3
Bishop, J.M.4
-
12
-
-
0013659750
-
Carcinogen-Induced mdr Overexpression Is Associated with Xenobiotic Resistance in Rat Preneoplastic Liver Nodules and Hepatocellular Carcinomas
-
Fairchild, C. R.; Ivy, S. P.; Rushmore, T.; Lee, G.; Koo, P.; Goldsmith, M. E.; Myers, C. E.; Farber, E.; Cowan, K. Carcinogen-Induced mdr Overexpression Is Associated with Xenobiotic Resistance in Rat Preneoplastic Liver Nodules and Hepatocellular Carcinomas. Proc. Natl. Acad. Sci. U. S. A. 1987, 84, 7701-7705.
-
(1987)
Proc. Natl. Acad. Sci. U. S. A
, vol.84
, pp. 7701-7705
-
-
Fairchild, C.R.1
Ivy, S.P.2
Rushmore, T.3
Lee, G.4
Koo, P.5
Goldsmith, M.E.6
Myers, C.E.7
Farber, E.8
Cowan, K.9
-
13
-
-
0028032185
-
Expression and Function of P-glycoprotein in Human Mesangial Cells
-
Bello-Reuss, E.; Ernest, S. Expression and Function of P-glycoprotein in Human Mesangial Cells. Am. J. Physiol. 1994, 267, C1351-C1358.
-
(1994)
Am. J. Physiol
, vol.267
-
-
Bello-Reuss, E.1
Ernest, S.2
-
14
-
-
14644409841
-
The Breast Cancer Resistance Protein BCRP (ABCG2) Concentrates Drugs and Carcinogenic Xenotoxins into Milk
-
Jonker, J. W.; Merino, G.; Musters, S.; van Herwaarden, A. E.; Bolscher, E.; Wagenaar, E.; Mesman, E.; Dale, T. C.; Schinkel, A. H. The Breast Cancer Resistance Protein BCRP (ABCG2) Concentrates Drugs and Carcinogenic Xenotoxins into Milk. Nat. Med. 2005, 11, 127-129.
-
(2005)
Nat. Med
, vol.11
, pp. 127-129
-
-
Jonker, J.W.1
Merino, G.2
Musters, S.3
van Herwaarden, A.E.4
Bolscher, E.5
Wagenaar, E.6
Mesman, E.7
Dale, T.C.8
Schinkel, A.H.9
-
15
-
-
16644394284
-
Isolation and Characterization of Side Population Cells
-
Goodell, M. A.; McKinney-Freeman, S.; Camargo, F. D. Isolation and Characterization of Side Population Cells. Methods Mol. Biol. 2005, 290, 343-352.
-
(2005)
Methods Mol. Biol
, vol.290
, pp. 343-352
-
-
Goodell, M.A.1
McKinney-Freeman, S.2
Camargo, F.D.3
-
16
-
-
0029958876
-
Isolation and Functional Properties of Murine Hematopoietic Stem Cells That Are Replicating In Vivo
-
Goodell, M. A.; Brose, K.; Paradis, G.; Conner, A. S.; Mulligan, R. C. Isolation and Functional Properties of Murine Hematopoietic Stem Cells That Are Replicating In Vivo. J. Exp. Med. 1996, 183, 1797-1806.
-
(1996)
J. Exp. Med
, vol.183
, pp. 1797-1806
-
-
Goodell, M.A.1
Brose, K.2
Paradis, G.3
Conner, A.S.4
Mulligan, R.C.5
-
17
-
-
34250306257
-
Side Population in Human Lung Cancer Cell Lines and Tumors Is Enriched with Stem-Like Cancer Cells
-
Ho, M. M.; Ng, A. V.; Lam, S.; Hung, J. Y. Side Population in Human Lung Cancer Cell Lines and Tumors Is Enriched with Stem-Like Cancer Cells. Cancer Res. 2007, 67, 4827-4833.
-
(2007)
Cancer Res
, vol.67
, pp. 4827-4833
-
-
Ho, M.M.1
Ng, A.V.2
Lam, S.3
Hung, J.Y.4
-
18
-
-
1642474273
-
Persistence of a Small Subpopulation of Cancer Stem-Like Cells in the C6 Glioma Cell Line
-
Kondo, T.; Setoguchi, T.; Taga, T. Persistence of a Small Subpopulation of Cancer Stem-Like Cells in the C6 Glioma Cell Line. Proc. Natl. Acad. Sci. U. S. A. 2004, 101, 781-786.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A
, vol.101
, pp. 781-786
-
-
Kondo, T.1
Setoguchi, T.2
Taga, T.3
-
19
-
-
33750991688
-
Cancer Stem Cells in Human Gastrointestinal Cancers
-
Haraguchi, N.; Inoue, H.; Tanaka, F.; Mimori, K.; Utsunomiya, T.; Sasaki, A.; Mori, M. Cancer Stem Cells in Human Gastrointestinal Cancers. Hum. Cell 2006, 19, 24-29.
-
(2006)
Hum. Cell
, vol.19
, pp. 24-29
-
-
Haraguchi, N.1
Inoue, H.2
Tanaka, F.3
Mimori, K.4
Utsunomiya, T.5
Sasaki, A.6
Mori, M.7
-
20
-
-
33746625091
-
Ovarian Cancer Side Population Defines Cells With Stem Cell-Like Characteristics and Mullerian Inhibiting Substance Responsiveness
-
Szotek, P. P.; Pieretti-Vanmarcke, R.; Masiakos, P. T.; Dinulescu, D. M.; Connolly, D.; Foster, R.; Dombkowski, D.; Preffer, F.; Maclaughlin, D. T.; Donahoe, P. K.; et al. Ovarian Cancer Side Population Defines Cells With Stem Cell-Like Characteristics and Mullerian Inhibiting Substance Responsiveness. Proc. Natl. Acad. Sci. U. S. A. 2006, 103, 11154-11159.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A
, vol.103
, pp. 11154-11159
-
-
Szotek, P.P.1
Pieretti-Vanmarcke, R.2
Masiakos, P.T.3
Dinulescu, D.M.4
Connolly, D.5
Foster, R.6
Dombkowski, D.7
Preffer, F.8
McLaughlin, D.T.9
Donahoe, P.K.10
-
21
-
-
0036202207
-
Cellular Levels of Aldehyde Dehydrogenases (ALDH1A1 and ALDH3A1) as Predictors of Therapeutic Responses to Cyclophosphamide-Based Chemotherapy of Breast Cancer: A Retrospective Study. Rational Individualization of Oxazaphosphorine-Based Cancer Chemotherapeutic Regimens
-
Sladek, N. E.; Kollander, R.; Sreerama, L.; Kiang, D. T. Cellular Levels of Aldehyde Dehydrogenases (ALDH1A1 and ALDH3A1) as Predictors of Therapeutic Responses to Cyclophosphamide-Based Chemotherapy of Breast Cancer: A Retrospective Study. Rational Individualization of Oxazaphosphorine-Based Cancer Chemotherapeutic Regimens. Cancer Chemother. Pharmacol. 2002, 49, 309-321.
-
(2002)
Cancer Chemother. Pharmacol
, vol.49
, pp. 309-321
-
-
Sladek, N.E.1
Kollander, R.2
Sreerama, L.3
Kiang, D.T.4
-
22
-
-
66249139555
-
CD44+ Cancer Cells Express Higher Levels of the Anti-Apoptotic Protein Bcl-2 in Breast Tumours
-
Madjd, Z.; Mehrjerdi, A. Z.; Sharifi, A. M.; Molanaei, S.; Shahzadi, S. Z.; Asadi-Lari, M. CD44+ Cancer Cells Express Higher Levels of the Anti-Apoptotic Protein Bcl-2 in Breast Tumours. Cancer Immun. 2009, 9, 4.
-
(2009)
Cancer Immun
, vol.9
, pp. 4
-
-
Madjd, Z.1
Mehrjerdi, A.Z.2
Sharifi, A.M.3
Molanaei, S.4
Shahzadi, S.Z.5
Asadi-Lari, M.6
-
23
-
-
40749150740
-
CD133+ HCC Cancer Stem Cells Confer Chemoresistance by Preferential Expression of the Akt/PKB Survival Pathway
-
Ma, S.; Lee, T. K.; Zheng, B. J.; Chan, K. W.; Guan, X. Y. CD133+ HCC Cancer Stem Cells Confer Chemoresistance by Preferential Expression of the Akt/PKB Survival Pathway. Oncogene 2008, 27, 1749-1758.
-
(2008)
Oncogene
, vol.27
, pp. 1749-1758
-
-
Ma, S.1
Lee, T.K.2
Zheng, B.J.3
Chan, K.W.4
Guan, X.Y.5
-
24
-
-
77953164298
-
Aurora-a Is Essential for the Tumorigenic Capacity and Chemoresistance of Colorectal Cancer Stem Cells
-
Cammareri, P.; Scopelliti, A.; Todaro, M.; Eterno, V.; Francescangeli, F.; Moyer, M. P.; Agrusa, A.; Dieli, F.; Zeuner, A.; Stassi, G. Aurora-a Is Essential for the Tumorigenic Capacity and Chemoresistance of Colorectal Cancer Stem Cells. Cancer Res. 2010, 70, 4655-4665.
-
(2010)
Cancer Res
, vol.70
, pp. 4655-4665
-
-
Cammareri, P.1
Scopelliti, A.2
Todaro, M.3
Eterno, V.4
Francescangeli, F.5
Moyer, M.P.6
Agrusa, A.7
Dieli, F.8
Zeuner, A.9
Stassi, G.10
-
25
-
-
79959622792
-
Cucurbitacin I Inhibits Tumorigenic Ability and Enhances Radiochemosensitivity in Nonsmall Cell Lung Cancer-Derived CD133-Positive Cells
-
Hsu, H. S.; Huang, P. I.; Chang, Y. L.; Tzao, C.; Chen, Y. W.; Shih, H. C.; Hung, S. C.; Chen, Y. C.; Tseng, L. M.; Chiou, S. H. Cucurbitacin I Inhibits Tumorigenic Ability and Enhances Radiochemosensitivity in Nonsmall Cell Lung Cancer-Derived CD133-Positive Cells. Cancer 2011, 117, 2970-2985.
-
(2011)
Cancer
, vol.117
, pp. 2970-2985
-
-
Hsu, H.S.1
Huang, P.I.2
Chang, Y.L.3
Tzao, C.4
Chen, Y.W.5
Shih, H.C.6
Hung, S.C.7
Chen, Y.C.8
Tseng, L.M.9
Chiou, S.H.10
-
26
-
-
34848866647
-
Colon Cancer Stem Cells Dictate Tumor Growth and Resist Cell Death by Production of Interleukin-4
-
Todaro, M.; Alea, M. P.; Di Stefano, A. B.; Cammareri, P.; Vermeulen, L.; Iovino, F.; Tripodo, C.; Russo, A.; Gulotta, G.; Medema, J. P.; et al. Colon Cancer Stem Cells Dictate Tumor Growth and Resist Cell Death by Production of Interleukin-4. Cell Stem Cell 2007, 1, 389-402.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 389-402
-
-
Todaro, M.1
Alea, M.P.2
Di Stefano, A.B.3
Cammareri, P.4
Vermeulen, L.5
Iovino, F.6
Tripodo, C.7
Russo, A.8
Gulotta, G.9
Medema, J.P.10
-
27
-
-
79953013766
-
Inhibition of Ataxia Telangiectasia-and Rad3-Related Function Abrogates the In Vitro and In Vivo Tumorigenicity of Human Colon Cancer Cells through Depletion of the CD133(+) Tumor-Initiating Cell Fraction
-
Gallmeier, E.; Hermann, P. C.; Mueller, M. T.; Machado, J. G.; Ziesch, A.; De Toni, E. N.; Palagyi, A.; Eisen, C.; Ellwart, J. W.; Rivera, J.; et al. Inhibition of Ataxia Telangiectasia-and Rad3-Related Function Abrogates the In Vitro and In Vivo Tumorigenicity of Human Colon Cancer Cells through Depletion of the CD133(+) Tumor-Initiating Cell Fraction. Stem Cells 2011, 29, 418-429.
-
(2011)
Stem Cells
, vol.29
, pp. 418-429
-
-
Gallmeier, E.1
Hermann, P.C.2
Mueller, M.T.3
McHado, J.G.4
Ziesch, A.5
de Toni, E.N.6
Palagyi, A.7
Eisen, C.8
Ellwart, J.W.9
Rivera, J.10
-
28
-
-
24944450475
-
Effects of Imatinib and Interferon on Primitive Chronic Myeloid Leukaemia Progenitors
-
Angstreich, G. R.; Matsui, W.; Huff, C. A.; Vala, M. S.; Barber, J.; Hawkins, A. L.; Griffin, C. A.; Smith, B. D.; Jones, R. J. Effects of Imatinib and Interferon on Primitive Chronic Myeloid Leukaemia Progenitors. Br. J. Haematol. 2005, 130, 373-381.
-
(2005)
Br. J. Haematol
, vol.130
, pp. 373-381
-
-
Angstreich, G.R.1
Matsui, W.2
Huff, C.A.3
Vala, M.S.4
Barber, J.5
Hawkins, A.L.6
Griffin, C.A.7
Smith, B.D.8
Jones, R.J.9
-
29
-
-
78650625238
-
Imatinib plus Peginterferon alfa-2a in Chronic Myeloid Leukemia
-
Preudhomme, C.; Guilhot, J.; Nicolini, F. E.; Guerci-Bresler, A.; Rigal-Huguet, F.; Maloisel, F.; Coiteux, V.; Gardembas, M.; Berthou, C.; Vekhoff, A.; et al. Imatinib plus Peginterferon alfa-2a in Chronic Myeloid Leukemia. N. Engl. J. Med. 2010, 363, 2511-2521.
-
(2010)
N. Engl. J. Med
, vol.363
, pp. 2511-2521
-
-
Preudhomme, C.1
Guilhot, J.2
Nicolini, F.E.3
Guerci-Bresler, A.4
Rigal-Huguet, F.5
Maloisel, F.6
Coiteux, V.7
Gardembas, M.8
Berthou, C.9
Vekhoff, A.10
-
30
-
-
80053130415
-
Combination of Pegylated IFN-alpha2b with Imatinib Increases Molecular Response Rates in Patients with Low-or Intermediate-Risk Chronic Myeloid Leukemia
-
Simonsson, B.; Gedde-Dahl, T.; Markevärn, B.; Remes, K.; Stentoft, J.; Almqvist, A.; Björeman, M.; Flogegård, M.; Koskenvesa, P.; Lindblom, A.; et al. Combination of Pegylated IFN-alpha2b with Imatinib Increases Molecular Response Rates in Patients with Low-or Intermediate-Risk Chronic Myeloid Leukemia. Blood 2011, 118, 3228-3235.
-
(2011)
Blood
, vol.118
, pp. 3228-3235
-
-
Simonsson, B.1
Gedde-Dahl, T.2
Markevärn, B.3
Remes, K.4
Stentoft, J.5
Almqvist, A.6
Björeman, M.7
Flogegård, M.8
Koskenvesa, P.9
Lindblom, A.10
-
31
-
-
33845610993
-
Bone Morphogenetic Proteins Inhibit the Tumorigenic Potential of Human Brain Tumour-Initiating Cells
-
Piccirillo, S. G.; Reynolds, B. A.; Zanetti, N.; Lamorte, G.; Binda, E.; Broggi, G.; Brem, H.; Olivi, A.; Dimeco, F.; Vescovi, A. L. Bone Morphogenetic Proteins Inhibit the Tumorigenic Potential of Human Brain Tumour-Initiating Cells. Nature 2006, 444, 761-765.
-
(2006)
Nature
, vol.444
, pp. 761-765
-
-
Piccirillo, S.G.1
Reynolds, B.A.2
Zanetti, N.3
Lamorte, G.4
Binda, E.5
Broggi, G.6
Brem, H.7
Olivi, A.8
Dimeco, F.9
Vescovi, A.L.10
-
32
-
-
0037223971
-
The Evolution of Signalling Pathways in Animal Development
-
Pires-daSilva, A.; Sommer, R. J. The Evolution of Signalling Pathways in Animal Development. Nat. Rev. Genet. 2003, 4, 39-49.
-
(2003)
Nat. Rev. Genet
, vol.4
, pp. 39-49
-
-
Pires-daSilva, A.1
Sommer, R.J.2
-
33
-
-
84862780640
-
Sonic Hedgehog Maintains Survival and Growth of Chronic Myeloid Leukemia Progenitor Cells through beta-Catenin Signaling
-
Su, W.; Meng, F.; Huang, L.; Zheng, M.; Liu, W.; Sun, H. Sonic Hedgehog Maintains Survival and Growth of Chronic Myeloid Leukemia Progenitor Cells through beta-Catenin Signaling. Exp. Hematol. 2012, 40, 418-427.
-
(2012)
Exp. Hematol
, vol.40
, pp. 418-427
-
-
Su, W.1
Meng, F.2
Huang, L.3
Zheng, M.4
Liu, W.5
Sun, H.6
-
34
-
-
45549091581
-
Medulloblastoma Stem Cells
-
Fan, X.; Eberhart, C. G. Medulloblastoma Stem Cells. J. Clin. Oncol. 2008, 26, 2821-2827.
-
(2008)
J. Clin. Oncol
, vol.26
, pp. 2821-2827
-
-
Fan, X.1
Eberhart, C.G.2
-
35
-
-
33745728170
-
Hedgehog Signaling and Bmi-1 Regulate Self-Renewal of Normal and Malignant Human Mammary Stem Cells
-
Liu, S.; Dontu, G.; Mantle, I. D.; Patel, S.; Ahn, N.; Jackson, K.; Suri, P.; Wicha, M. Hedgehog Signaling and Bmi-1 Regulate Self-Renewal of Normal and Malignant Human Mammary Stem Cells. Cancer Res. 2006, 66, 6063-6071.
-
(2006)
Cancer Res
, vol.66
, pp. 6063-6071
-
-
Liu, S.1
Dontu, G.2
Mantle, I.D.3
Patel, S.4
Ahn, N.5
Jackson, K.6
Suri, P.7
Wicha, M.8
-
36
-
-
33847052127
-
Identification of Pancreatic Cancer Stem Cells
-
Li, C.; Heidt, D. G.; Dalerba, P.; Burant, C. F.; Zhang, L.; Adsay, V.; Wicha, M.; Clarke, M. F.; Simeone, D. M. Identification of Pancreatic Cancer Stem Cells. Cancer Res. 2007, 67, 1030-1037.
-
(2007)
Cancer Res
, vol.67
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
Burant, C.F.4
Zhang, L.5
Adsay, V.6
Wicha, M.7
Clarke, M.F.8
Simeone, D.M.9
-
37
-
-
80052947064
-
Epithelial Mesenchymal Transition and Hedgehog Signaling Activation Are Associated with Chemoresistance and Invasion of Hepatoma Subpopulations
-
Chen, X.; Lingala, S.; Khoobyari, S.; Nolta, J.; Zern, M. A.; Wu, J. Epithelial Mesenchymal Transition and Hedgehog Signaling Activation Are Associated with Chemoresistance and Invasion of Hepatoma Subpopulations. J. Hepatol. 2011, 55, 838-845.
-
(2011)
J. Hepatol
, vol.55
, pp. 838-845
-
-
Chen, X.1
Lingala, S.2
Khoobyari, S.3
Nolta, J.4
Zern, M.A.5
Wu, J.6
-
38
-
-
70349244812
-
Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449
-
Rudin, C. M.; Hann, C. L.; Laterra, J.; Yauch, R. L.; Callahan, C. A.; Fu, L.; Holcomb, T.; Stinson, J.; Gould, S. E.; Coleman, B.; et al. Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449. N. Engl. J. Med. 2009, 361, 1173-1178.
-
(2009)
N. Engl. J. Med
, vol.361
, pp. 1173-1178
-
-
Rudin, C.M.1
Hann, C.L.2
Laterra, J.3
Yauch, R.L.4
Callahan, C.A.5
Fu, L.6
Holcomb, T.7
Stinson, J.8
Gould, S.E.9
Coleman, B.10
-
39
-
-
79954611501
-
Phase I Trial of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Refractory, Locally Advanced or Metastatic Solid Tumors
-
LoRusso, P. M.; Rudin, C. M.; Reddy, J. C.; Tibes, R.; Weiss, G. J.; Borad, M. J.; Hann, C. L.; Brahmer, J. R.; Chang, I.; Darbonne, W. C.; et al. Phase I Trial of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Refractory, Locally Advanced or Metastatic Solid Tumors. Clin. Cancer Res. 2011, 17, 2502-2511.
-
(2011)
Clin. Cancer Res
, vol.17
, pp. 2502-2511
-
-
LoRusso, P.M.1
Rudin, C.M.2
Reddy, J.C.3
Tibes, R.4
Weiss, G.J.5
Borad, M.J.6
Hann, C.L.7
Brahmer, J.R.8
Chang, I.9
Darbonne, W.C.10
-
40
-
-
0035893568
-
Evidence That APC Regulates Survivin Expression: A Possible Mechanism Contributing to the Stem Cell Origin of Colon Cancer
-
Zhang, T.; Otevrel, T.; Gao, Z.; Ehrlich, S. M.; Fields, J. Z.; Boman, B. M. Evidence That APC Regulates Survivin Expression: A Possible Mechanism Contributing to the Stem Cell Origin of Colon Cancer. Cancer Res. 2001, 61, 8664-8667.
-
(2001)
Cancer Res
, vol.61
, pp. 8664-8667
-
-
Zhang, T.1
Otevrel, T.2
Gao, Z.3
Ehrlich, S.M.4
Fields, J.Z.5
Boman, B.M.6
-
41
-
-
70350212976
-
STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells
-
Sherry, M. M.; Reeves, A.; Wu, J. K.; Cochran, B. H. STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells. Stem Cells 2009, 27, 2383-2392.
-
(2009)
Stem Cells
, vol.27
, pp. 2383-2392
-
-
Sherry, M.M.1
Reeves, A.2
Wu, J.K.3
Cochran, B.H.4
-
42
-
-
0037673984
-
Bmi-1 Determines the Proliferative Capacity of Normal and Leukaemic Stem Cells
-
Lessard, J.; Sauvageau, G. Bmi-1 Determines the Proliferative Capacity of Normal and Leukaemic Stem Cells. Nature 2003, 423, 255-260.
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
43
-
-
70349507504
-
In Vitro Propagation and Characterization of Neoplastic Stem/Progenitor-Like Cells from Human Prostate Cancer Tissue
-
Guzmán-Ramírez, N.; Völler, M.; Wetterwald, A.; Germann, M.; Cross, N. A.; Rentsch, C. A.; Schalken, J.; Thalmann, G. N.; Cecchini, M. G. In Vitro Propagation and Characterization of Neoplastic Stem/Progenitor-Like Cells from Human Prostate Cancer Tissue. Prostate 2009, 69, 1683-1693.
-
(2009)
Prostate
, vol.69
, pp. 1683-1693
-
-
Guzmán-Ramírez, N.1
Völler, M.2
Wetterwald, A.3
Germann, M.4
Cross, N.A.5
Rentsch, C.A.6
Schalken, J.7
Thalmann, G.N.8
Cecchini, M.G.9
-
44
-
-
79952461058
-
Nanodiamond Therapeutic Delivery Agents Mediate Enhanced Chemoresistant Tumor Treatment
-
Chow, E. K.; Zhang, X. Q.; Chen, M.; Lam, R.; Robinson, E.; Huang, H.; Schaffer, D.; Osawa, E.; Goga, A.; Ho, D. Nanodiamond Therapeutic Delivery Agents Mediate Enhanced Chemoresistant Tumor Treatment. Sci. Transl. Med. 2011, 3, 73ra21.
-
(2011)
Sci. Transl. Med
, vol.3
-
-
Chow, E.K.1
Zhang, X.Q.2
Chen, M.3
Lam, R.4
Robinson, E.5
Huang, H.6
Schaffer, D.7
Osawa, E.8
Goga, A.9
Ho, D.10
-
45
-
-
36749086476
-
Active Nanodiamond Hydrogels for Chemotherapeutic Delivery
-
Huang, H.; Pierstorff, E.; Osawa, E.; Ho, D. Active Nanodiamond Hydrogels for Chemotherapeutic Delivery. Nano. Lett. 2007, 7, 3305-3314.
-
(2007)
Nano. Lett
, vol.7
, pp. 3305-3314
-
-
Huang, H.1
Pierstorff, E.2
Osawa, E.3
Ho, D.4
-
46
-
-
70349548902
-
Polymer-Functionalized Nanodiamond Platforms as Vehicles for Gene Delivery
-
Zhang, X. Q.; Chen, M.; Lam, R.; Xu, X.; Osawa, E.; Ho, D. Polymer-Functionalized Nanodiamond Platforms as Vehicles for Gene Delivery. ACS Nano. 2009, 3, 2609-2616.
-
(2009)
ACS Nano
, vol.3
, pp. 2609-2616
-
-
Zhang, X.Q.1
Chen, M.2
Lam, R.3
Xu, X.4
Osawa, E.5
Ho, D.6
-
47
-
-
76749154112
-
Gd(III)-nanodiamond Conjugates for MRI Contrast Enhancement
-
Manus, L. M.; Mastarone, D. J.; Waters, E. A.; Zhang, X. Q.; Schultz-Sikma, E. A.; Macrenaris, K. W.; Ho, D.; Meade, T. J. Gd(III)-nanodiamond Conjugates for MRI Contrast Enhancement. Nano. Lett. 2010, 10, 484-489.
-
(2010)
Nano. Lett
, vol.10
, pp. 484-489
-
-
Manus, L.M.1
Mastarone, D.J.2
Waters, E.A.3
Zhang, X.Q.4
Schultz-Sikma, E.A.5
McRenaris, K.W.6
Ho, D.7
Meade, T.J.8
-
48
-
-
53049104252
-
Drug Delivery with Carbon Nanotubes for In Vivo Cancer Treatment
-
Liu, Z.; Chen, K.; Davis, C.; Sherlock, S.; Cao, Q.; Chen, X.; Dai, H. Drug Delivery with Carbon Nanotubes for In Vivo Cancer Treatment. Cancer Res. 2008, 68, 6652-6660.
-
(2008)
Cancer Res
, vol.68
, pp. 6652-6660
-
-
Liu, Z.1
Chen, K.2
Davis, C.3
Sherlock, S.4
Cao, Q.5
Chen, X.6
Dai, H.7
-
49
-
-
44649133215
-
A Potential Target Associated with Both Cancer and Cancer Stem Cells: A Combination Therapy for Eradication of Breast Cancer Using Vinorelbine Stealthy Liposomes plus Parthenolide Stealthy Liposomes
-
Liu, Y.; Lu, W. L.; Guo, J.; Du, J.; Li, T.; Wu, J. W.; Wang, G. L.; Wang, J. C.; Zhang, X.; Zhang, Q. A Potential Target Associated with Both Cancer and Cancer Stem Cells: A Combination Therapy for Eradication of Breast Cancer Using Vinorelbine Stealthy Liposomes plus Parthenolide Stealthy Liposomes. J. Control. Release 2008, 129, 18-25.
-
(2008)
J. Control. Release
, vol.129
, pp. 18-25
-
-
Liu, Y.1
Lu, W.L.2
Guo, J.3
Du, J.4
Li, T.5
Wu, J.W.6
Wang, G.L.7
Wang, J.C.8
Zhang, X.9
Zhang, Q.10
-
50
-
-
0037100463
-
Strategy for the Treatment of Acute Myelogenous Leukemia Based on Folate Receptor beta-Targeted Liposomal Doxorubicin Combined with Receptor Induction Using All-Trans Retinoic Acid
-
Pan, X. Q.; Zheng, X.; Shi, G.; Wang, H.; Ratnam, M.; Lee, R. J. Strategy for the Treatment of Acute Myelogenous Leukemia Based on Folate Receptor beta-Targeted Liposomal Doxorubicin Combined with Receptor Induction Using All-Trans Retinoic Acid. Blood 2002, 100, 594-602.
-
(2002)
Blood
, vol.100
, pp. 594-602
-
-
Pan, X.Q.1
Zheng, X.2
Shi, G.3
Wang, H.4
Ratnam, M.5
Lee, R.J.6
-
51
-
-
0034671316
-
Antibody Targeting of Doxorubicin-Loaded Liposomes Suppresses the Growth and Metastatic Spread of Established Human Lung Tumor Xenografts in Severe Combined Immunodeficient Mice
-
Sugano, M.; Egilmez, N. K.; Yokota, S. J.; Chen, F. A.; Harding, J.; Huang, S. K.; Bankert, R. B. Antibody Targeting of Doxorubicin-Loaded Liposomes Suppresses the Growth and Metastatic Spread of Established Human Lung Tumor Xenografts in Severe Combined Immunodeficient Mice. Cancer Res. 2000, 60, 6942-6949.
-
(2000)
Cancer Res
, vol.60
, pp. 6942-6949
-
-
Sugano, M.1
Egilmez, N.K.2
Yokota, S.J.3
Chen, F.A.4
Harding, J.5
Huang, S.K.6
Bankert, R.B.7
-
52
-
-
4644349816
-
Liposomes Modified with Cyclic RGD Peptide for Tumor Targeting
-
Dubey, P. K.; Mishra, V.; Jain, S.; Mahor, S.; Vyas, S. P. Liposomes Modified with Cyclic RGD Peptide for Tumor Targeting. J. Drug Target 2004, 12, 257-264.
-
(2004)
J. Drug Target
, vol.12
, pp. 257-264
-
-
Dubey, P.K.1
Mishra, V.2
Jain, S.3
Mahor, S.4
Vyas, S.P.5
-
53
-
-
0038162536
-
Integrin-Mediated Targeting of Drug Delivery to Irradiated Tumor Blood Vessels
-
Hallahan, D.; Geng, L.; Qu, S.; Scarfone, C.; Giorgio, T.; Donnelly, E.; Gao, X.; Clanton, J. Integrin-Mediated Targeting of Drug Delivery to Irradiated Tumor Blood Vessels. Cancer Cell 2003, 3, 63-74.
-
(2003)
Cancer Cell
, vol.3
, pp. 63-74
-
-
Hallahan, D.1
Geng, L.2
Qu, S.3
Scarfone, C.4
Giorgio, T.5
Donnelly, E.6
Gao, X.7
Clanton, J.8
-
54
-
-
34547193404
-
Phenotypic Characterization of Human Colorectal Cancer Stem Cells
-
Dalerba, P.; Dylla, S. J.; Park, I. K.; Liu, R.; Wang, X.; Cho, R. W.; Hoey, T.; Gurney, A.; Huang, E. H.; Simeone, D. M.; et al. Phenotypic Characterization of Human Colorectal Cancer Stem Cells. Proc. Natl. Acad. Sci. U. S. A. 2007, 104, 10158-10163.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A
, vol.104
, pp. 10158-10163
-
-
Dalerba, P.1
Dylla, S.J.2
Park, I.K.3
Liu, R.4
Wang, X.5
Cho, R.W.6
Hoey, T.7
Gurney, A.8
Huang, E.H.9
Simeone, D.M.10
-
55
-
-
0035866799
-
Liposome-Encapsulated Doxorubicin Targeted to CD44: A Strategy to Kill CD44-Overexpressing Tumor Cells
-
Eliaz, R. E.; Szoka, F. C., Jr. Liposome-Encapsulated Doxorubicin Targeted to CD44: A Strategy to Kill CD44-Overexpressing Tumor Cells. Cancer Res. 2001, 61, 2592-2601.
-
(2001)
Cancer Res
, vol.61
, pp. 2592-2601
-
-
Eliaz, R.E.1
Szoka Jr., F.C.2
-
56
-
-
33646582037
-
Targeted Nanoparticle-Aptamer Bioconjugates for Cancer Chemotherapy In Vivo
-
Farokhzad, O. C.; Cheng, J.; Teply, B. A.; Sherifi, I.; Jon, S.; Kantoff, P. W.; Richie, J. P.; Langer, R. Targeted Nanoparticle-Aptamer Bioconjugates for Cancer Chemotherapy In Vivo. Proc. Natl. Acad. Sci. U. S. A. 2006, 103, 6315-6320.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A
, vol.103
, pp. 6315-6320
-
-
Farokhzad, O.C.1
Cheng, J.2
Teply, B.A.3
Sherifi, I.4
Jon, S.5
Kantoff, P.W.6
Richie, J.P.7
Langer, R.8
-
57
-
-
7444223607
-
Nanoparticle-Aptamer Bioconjugates: A New Approach for Targeting Prostate Cancer Cells
-
Farokhzad, O. C.; Jon, S.; Khademhosseini, A.; Tran, T. N.; Lavan, D. A.; Langer, R. Nanoparticle-Aptamer Bioconjugates: A New Approach for Targeting Prostate Cancer Cells. Cancer Res. 2004, 64, 7668-7672.
-
(2004)
Cancer Res
, vol.64
, pp. 7668-7672
-
-
Farokhzad, O.C.1
Jon, S.2
Khademhosseini, A.3
Tran, T.N.4
Lavan, D.A.5
Langer, R.6
-
58
-
-
33644500132
-
Antitumor Efficacy of a Novel Polymer-Peptide-Drug Conjugate in Human Tumor Xenograft Models
-
Chau, Y.; Padera, R. F.; Dang, N. M.; Langer, R. Antitumor Efficacy of a Novel Polymer-Peptide-Drug Conjugate in Human Tumor Xenograft Models. Int. J. Cancer 2006, 118, 1519-1526.
-
(2006)
Int. J. Cancer
, vol.118
, pp. 1519-1526
-
-
Chau, Y.1
Padera, R.F.2
Dang, N.M.3
Langer, R.4
-
59
-
-
13644254794
-
Molecular Mechanisms of Drug Resistance
-
Longley, D. B.; Johnston, P. G. Molecular Mechanisms of Drug Resistance. J. Pathol. 2005, 205, 275-292.
-
(2005)
J. Pathol
, vol.205
, pp. 275-292
-
-
Longley, D.B.1
Johnston, P.G.2
|