Relationship between chromosomal instability and intratumoral regional DNA ploidy heterogeneity in primary gastric cancers

Clinical Cancer Research

Volumn 6, Issue 7, 2000, Pages 2815-2820

  Furuya, Tomoko ^a   Uchiyama, Tetsuji ^b   Murakami, Takuo ^b   Adachi, Atsushi ^b   Kawauchi, Shigeto ^a   Oga, Atsunori ^a   Hirano, Takashi ^c   Sasaki, Kohsuke ^a  

^a YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Iwakuni Medical Center   (Japan)

^c NATL INST BIOSCI HUM TECHNOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ADULT; ADVANCED CANCER; AGED; ANEUPLOIDY; ARTICLE; CANCER STAGING; CHROMOSOME 11; CHROMOSOME 17; CHROMOSOME 18; CHROMOSOME 7; CHROMOSOME ABERRATION; CLINICAL ARTICLE; DIPLOIDY; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; STOMACH ADENOCARCINOMA;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ANEUPLOIDY; CHROMOSOME ABERRATIONS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 17; CHROMOSOMES, HUMAN, PAIR 18; CHROMOSOMES, HUMAN, PAIR 7; DIPLOIDY; DNA, NEOPLASM; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MIDDLE AGED; PLOIDIES; STOMACH NEOPLASMS;

EID: 0033912369     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Lengauer, C., Kinzler, K. W., and Vogelstein, B. Genetic instability in colorectal cancers. Nature (Lond.), 386: 623-627, 1997.
2. Lengauer, C., Kinzler, K. W., and Vogelstein, B. DNA methylation and genetic instability in colorectal cancer cells. Proc. Natl. Acad. Sci. USA, 94: 2545-2550, 1997.
3. Lengauer, C., Kinzler, K. W., and Vogelstein, B. Genetic instabilities in human cancers. Nature (Lond.), 396: 643-649, 1998.
4. Cahill, D. P., Lengauer, C., Yu, J., Riggins, G. J., Willson, J. K. V., Markowitz, S. D., Kinzler, K. W., and Vogelstein, B. Mutations of mitotic checkpoint genes in human cancers. Nature (Lond.), 392: 300-303, 1998.
5. Marra, G., and Boland, C. R. Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives. J. Natl. Cancer Inst., 87: 1114-1125, 1995.
6. Bhattacharyya, N. P., Skandalis, A., Ganesh, A., Groden, J., and Meuth, M. Mutator phenotypes in human colorectal carcinoma cell lines. Proc. Natl. Acad. Sci. USA, 87: 7555-7559, 1990.
7. Pihan, G. A., Purohit, A., Wallace, J., Knecht, H., Woda, B., Quesenberry, P., and Doxsey, S. J. Centrosome defects and genetic instability in malignant tumors. Cancer Res., 58: 3974-3985, 1998.
8. Zhou, H., Kuang, J., Zhong, L., Kuo, W., Gray, J. W., Sahin, A., Brinkley, B. R., and Sen, S. Tumor amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat. Genet., 20: 189-193, 1998.
9. Chong, J. M., Fukayama, M., Hayashi, Y., Takizawa, T., Koike, M., Konishi, M., Kikuchi-Yanoshita, R., and Miyaki, M. MIN in the progression of gastric carcinoma. Cancer Res., 54: 4595-4597, 1994.
10. Seruca, R., Santos, N. R., David, L., Constancia, M., Barroca, H., Carneiro, F., Seixas, M., Peltomaki, P., Lothe, R., and Sobrinho-Simoes, M. Sporadic gastric carcinomas with microsatellite instability display a particular clinicopathologic profile. Int. J. Cancer, 64: 32-36, 1995.
11. Peruncho, M. Cancer of the microsatellite mutator phenotype. J. Biol. Chem., 377: 675-684, 1996.
12. Miyazaki, M., Furuya, T., Shiraki, A., Sato, T., Oga, A., and Sasaki, K. The relationship of DNA ploidy to chromosomal instability in primary human colorectal cancers. Cancer Res., 59: 5283-5285, 1999.
13. Sasaki, K., Kurose, A., Miura, Y., Sato, T., and Ikeda, E. DNA ploidy analysis by laser scanning cytometry (LSC) in colorectal cancers and comparison with flow cytometry. Cytometry, 23: 106-109, 1996.
14. Sasaki, K., Sato, T., Kurose, A., Uesugi, N., and Ikeda, E. Monosomy of chromosome 18 detected by fluorescence in situ hybridization in colorectal tumors. Cancer (Phila.), 76: 1132-1138, 1995.
15. Kamada, T., Sasaki, K., Tsuji, T., Takahashi, M., and Kurose, A. Sample preparation from paraffin-embedded tissue specimens for laser scanning cytometric DNA analysis. Cytometry, 27: 290-294, 1997.
16. Furuya, T., Kamada, T., Murakami, T., Kurose, A., and Sasaki, K. Laser scanning cytometry allows detection of cell death with morphological features of apoptosis in cells stained with PI. Cytometry, 29: 173-177, 1997.
17. Kawasaki, M., Sasaki, K., Satoh, T., Kurose, A., Kamada, T., Furuya, T., Murakami, T., and Todoroki, T. Laser scanning cytometry (LSC) allows detailed analysis of the cell cycle in PI stained human fibroblasts (TIG-7). Cell Prolif., 30: 139-147, 1997.
18. Hiddemann, W., Schumann, J., and reeff, M., Barlogie, B., Herman, C. J., Leif, R. C., Mayall, B. H., Murphy, R. F., and Sandberg, A. A. Convention on nomenclature for DNA cytometry. Cytometry, 5: 445-446, 1984.
19. Japanese Research Society for Gastric Cancer. Histological findings. In: Japanese Classification of Gastric Carcinoma, Ed. 12, pp. 60-107. Tokyo: Kanehara and Co., Ltd., 1995.
20. Fujimaki, E., Sasaki, K., Nakano, O., Chiba, S., Tazawa, H., Yamashiki, H., Orii, S., and Sugai, T. DNA ploidy heterogeneity in early and advanced gastric cancers. Cytometry, 26: 131-136, 1996.
21. Sasaki, K., Hashimoto, T., Kawachino, K., and Takahashi, M. Intratumoral regional differences in DNA ploidy of gastrointestinal carcinomas. Cancer (Phila.), 62: 2569-2575, 1988.
22. Sasaki, K., Takahashi, M., Hashimoto, T., and Kawachino, K. Flow cytometric DNA measurement of gastric cancers: clinicopathological implication of DNA ploidy. Pathol. Res. Pract., 184: 561-566, 1989.
23. Danova, M., Riccardi, A., Mazzini, G., Wilson, G., Dionigi, P., Brugnatelli, S., Fiocca, R., Ucci, G., Jemos, V., and Ascari, E. Flow cytometric analysis of paraffin-embedded material in human gastric cancer. Anal. Quant. Cytol. Histol., 10: 200-206, 1988.
24. Beerman, H., Smith, V. T. H. B. M., Kluin, P. M., Bonsing, B. A., Hermans, J., and Cornelisse, C. J. Flow cytometric analysis of DNA stemline heterogeneity in primary and metastatic breast cancer. Cytometry, 12: 147-154, 1991.
25. Maeda, K., Chung, Y. S., Kubo, T., Nishimura, M., Onoda, N., Nitta, A., Arimoto, Y., Kato, Y., and Sowa, M. Nuclear DNA ploidy pattern and proliferating cell nuclear antigen labeling index in gastric cancer with mucosal involvement. Gan To Kagaku Ryoho, 21 (Suppl 1): 58-61, 1994.