-
1
-
-
79960055459
-
RAS interaction with PI3K. More than just another effector pathway
-
Castellano, E., and Downward, J. (2011) RAS interaction with PI3K. More than just another effector pathway. Genes Cancer 2, 261-274
-
(2011)
Genes Cancer
, vol.2
, pp. 261-274
-
-
Castellano, E.1
Downward, J.2
-
2
-
-
0037542854
-
Ras proteins. Different signals from different locations
-
Hancock, J. F. (2003) Ras proteins. Different signals from different locations. Nat. Rev. Mol. Cell Biol. 4, 373-384
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 373-384
-
-
Hancock, J.F.1
-
3
-
-
84255195028
-
Regulating the regulator. Post-translational modification of RAS
-
Ahearn, I. M., Haigis, K., Bar-Sagi, D., and Philips, M. R. (2012) Regulating the regulator. Post-translational modification of RAS. Nat. Rev. Mol. Cell Biol. 13, 39-51
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 39-51
-
-
Ahearn, I.M.1
Haigis, K.2
Bar-Sagi, D.3
Philips, M.R.4
-
4
-
-
24744466287
-
DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras
-
DOI 10.1074/jbc.M504113200
-
Swarthout, J. T., Lobo, S., Farh, L., Croke, M. R., Greentree, W. K., Deschenes, R. J., and Linder, M. E. (2005) DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras. J. Biol. Chem. 280, 31141-31148 (Pubitemid 41291850)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.35
, pp. 31141-31148
-
-
Swarthout, J.T.1
Lobo, S.2
Farh, L.3
Croke, M.R.4
Greentree, W.K.5
Deschenes, R.J.6
Linder, M.E.7
-
5
-
-
61449215145
-
Ras acylation, compartmentalization, and signaling nanoclusters
-
Review
-
Henis, Y. I., Hancock, J. F., and Prior, I. A. (2009) Ras acylation, compartmentalization, and signaling nanoclusters (Review). Mol. Membr. Biol. 26, 80-92
-
(2009)
Mol. Membr. Biol.
, vol.26
, pp. 80-92
-
-
Henis, Y.I.1
Hancock, J.F.2
Prior, I.A.3
-
6
-
-
77952541156
-
Small-molecule inhibition of APT1 affects Ras localization and signaling
-
Dekker, F. J., Rocks, O., Vartak, N., Menninger, S., Hedberg, C., Balamurugan, R., Wetzel, S., Renner, S., Gerauer, M., Schölermann, B., Rusch, M., Kramer, J. W., Rauh, D., Coates, G. W., Brunsveld, L., Bastiaens, P. I., and Waldmann, H. (2010) Small-molecule inhibition of APT1 affects Ras localization and signaling. Nat. Chem. Biol. 6, 449-456
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 449-456
-
-
Dekker, F.J.1
Rocks, O.2
Vartak, N.3
Menninger, S.4
Hedberg, C.5
Balamurugan, R.6
Wetzel, S.7
Renner, S.8
Gerauer, M.9
Schölermann, B.10
Rusch, M.11
Kramer, J.W.12
Rauh, D.13
Coates, G.W.14
Brunsveld, L.15
Bastiaens, P.I.16
Waldmann, H.17
-
7
-
-
44949124597
-
Galectin-1 is a novel structural component and a major regulator of H-Ras nanoclusters
-
DOI 10.1091/mbc.E07-10-1053
-
Belanis, L., Plowman, S. J., Rotblat, B., Hancock, J. F., and Kloog, Y. (2008) Galectin-1 is a novel structural component and a major regulator of h-ras nanoclusters. Mol. Biol. Cell 19, 1404-1414 (Pubitemid 351805095)
-
(2008)
Molecular Biology of the Cell
, vol.19
, Issue.4
, pp. 1404-1414
-
-
Belanis, L.1
Plowman, S.J.2
Rotblat, B.3
Hancock, J.F.4
Kloog, Y.5
-
8
-
-
77957785819
-
H-Ras nanocluster stability regulates the magnitude of MAPK signal output
-
Rotblat, B., Belanis, L., Liang, H., Haklai, R., Elad-Zefadia, G., Hancock, J. F., Kloog, Y., and Plowman, S. J. (2010) H-Ras nanocluster stability regulates the magnitude of MAPK signal output. PLoS One 5, e11991
-
(2010)
PLoS One
, vol.5
-
-
Rotblat, B.1
Belanis, L.2
Liang, H.3
Haklai, R.4
Elad-Zefadia, G.5
Hancock, J.F.6
Kloog, Y.7
Plowman, S.J.8
-
9
-
-
78651468721
-
FKBP12 binds to acylated h-ras and promotes depalmitoylation
-
Ahearn, I. M., Tsai, F. D., Court, H., Zhou, M., Jennings, B. C., Ahmed, M., Fehrenbacher, N., Linder, M. E., and Philips, M. R. (2011) FKBP12 binds to acylated h-ras and promotes depalmitoylation. Mol. Cell 41, 173-185
-
(2011)
Mol. Cell
, vol.41
, pp. 173-185
-
-
Ahearn, I.M.1
Tsai, F.D.2
Court, H.3
Zhou, M.4
Jennings, B.C.5
Ahmed, M.6
Fehrenbacher, N.7
Linder, M.E.8
Philips, M.R.9
-
10
-
-
0018875887
-
Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry
-
Willingham, M. C., Pastan, I., Shih, T. Y., and Scolnick, E. M. (1980) Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry. Cell 19, 1005-1014 (Pubitemid 10155234)
-
(1980)
Cell
, vol.19
, Issue.4
, pp. 1005-1014
-
-
Willingham, M.C.1
Pastan, I.2
Shih, T.Y.3
Scolnick, E.M.4
-
11
-
-
0030461226
-
Control of EGF receptor signaling by clathrin-mediated endocytosis
-
DOI 10.1126/science.274.5295.2086
-
Vieira, A. V., Lamaze, C., and Schmid, S. L. (1996) Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274, 2086-2089 (Pubitemid 27020702)
-
(1996)
Science
, vol.274
, Issue.5295
, pp. 2086-2089
-
-
Vieira, A.V.1
Lamaze, C.2
Schmid, S.L.3
-
12
-
-
0036091925
-
Ras signalling on the endoplasmic reticulum and the Golgi
-
DOI 10.1038/ncb783
-
Chiu, V. K., Bivona, T., Hach, A., Sajous, J. B., Silletti, J., Wiener, H., Johnson, R. L., 2nd, Cox, A. D., and Philips, M. R. (2002) Ras signalling on the endoplasmic reticulum and the Golgi. Nat. Cell Biol. 4, 343-350 (Pubitemid 34521029)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.5
, pp. 343-350
-
-
Chiu, V.K.1
Bivona, T.2
Hach, A.3
Sajous, J.B.4
Silletti, J.5
Wiener, H.6
Johnson, R.L.7
Cox, A.D.8
Philips, M.R.9
-
13
-
-
79953140154
-
Demonstration of angiotensin II-induced Ras activation in the trans-Golgi network and endoplasmic reticulum using bioluminescence resonance energy transfer-based biosensors
-
Balla, A., Erdélyi, L. S., Soltész-Katona, E., Balla, T., Várnai, P., and Hunyady, L. (2011) Demonstration of angiotensin II-induced Ras activation in the trans-Golgi network and endoplasmic reticulum using bioluminescence resonance energy transfer-based biosensors. J. Biol. Chem. 286, 5319-5327
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 5319-5327
-
-
Balla, A.1
Erdélyi, L.S.2
Soltész-Katona, E.3
Balla, T.4
Várnai, P.5
Hunyady, L.6
-
14
-
-
0042386426
-
Differential αv integrin-mediated Ras-ERK signaling during two pathways of angiogenesis
-
DOI 10.1083/jcb.200304105
-
Hood, J. D., Frausto, R., Kiosses, W. B., Schwartz, M. A., and Cheresh, D. A. (2003) Differential αv integrin-mediated Ras-ERK signaling during two pathways of angiogenesis. J. Cell Biol. 162, 933-943 (Pubitemid 37087732)
-
(2003)
Journal of Cell Biology
, vol.162
, Issue.5
, pp. 933-943
-
-
Hood, J.D.1
Frausto, R.2
Kiosses, W.B.3
Schwartz, M.A.4
Cheresh, D.A.5
-
15
-
-
0942301171
-
Activated Ras induces a proangiogenic phenotype in primary endothelial cells
-
DOI 10.1038/sj.onc.1206921
-
Meadows, K. N., Bryant, P., Vincent, P. A., and Pumiglia, K. M. (2004) Activated Ras induces a proangiogenic phenotype in primary endothelial cells. Oncogene 23, 192-200 (Pubitemid 38142253)
-
(2004)
Oncogene
, vol.23
, Issue.1
, pp. 192-200
-
-
Meadows, K.N.1
Bryant, P.2
Vincent, P.A.3
Pumiglia, K.M.4
-
16
-
-
44949153658
-
H-ras regulates angiogenesis and vascular permeability by activation of distinct downstream effectors
-
Serban, D., Leng, J., and Cheresh, D. (2008) H-ras regulates angiogenesis and vascular permeability by activation of distinct downstream effectors. Circ. Res. 102, 1350-1358
-
(2008)
Circ. Res.
, vol.102
, pp. 1350-1358
-
-
Serban, D.1
Leng, J.2
Cheresh, D.3
-
17
-
-
77951758529
-
Activation of endothelial ras signaling bypasses senescence and causes abnormal vascular morphogenesis
-
Bajaj, A., Zheng, Q., Adam, A., Vincent, P., and Pumiglia, K. (2010) Activation of endothelial ras signaling bypasses senescence and causes abnormal vascular morphogenesis. Cancer Res. 70, 3803-3812
-
(2010)
Cancer Res.
, vol.70
, pp. 3803-3812
-
-
Bajaj, A.1
Zheng, Q.2
Adam, A.3
Vincent, P.4
Pumiglia, K.5
-
18
-
-
0033304596
-
16K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells
-
D'Angelo, G., Martini, J. F., Iiri, T., Fantl, W. J., Martial, J., and Weiner, R. I. (1999) 16K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells. Mol. Endocrinol. 13, 692-704 (Pubitemid 30645323)
-
(1999)
Molecular Endocrinology
, vol.13
, Issue.5
, pp. 692-704
-
-
D'Angelo, G.1
Martini, J.-F.2
Iiri, T.3
Fantl, W.J.4
Martial, J.5
Weiner, R.I.6
-
19
-
-
0033573895
-
VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases
-
DOI 10.1006/bbrc.1999.0227
-
Doanes, A. M., Hegland, D. D., Sethi, R., Kovesdi, I., Bruder, J. T., and Finkel, T. (1999) VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases. Biochem. Biophys. Res. Commun. 255, 545-548 (Pubitemid 29292296)
-
(1999)
Biochemical and Biophysical Research Communications
, vol.255
, Issue.2
, pp. 545-548
-
-
Doanes, A.M.1
Hegland, D.D.2
Sethi, R.3
Kovesdi, I.4
Bruder, J.T.5
Finkel, T.6
-
20
-
-
0348049834
-
VEGF signalling. Integration and multi-tasking in endothelial cell biology
-
Zachary, I. (2003) VEGF signalling. Integration and multi-tasking in endothelial cell biology. Biochem. Soc. Trans. 31, 1171-1177
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 1171-1177
-
-
Zachary, I.1
-
21
-
-
79961043835
-
Checkpoints in adenoviral production. Cross-contamination and E1A
-
Haeussler, D. J., Evangelista, A. M., Burgoyne, J. R., Cohen, R. A., Bachschmid, M. M., and Pimental, D. R. (2011) Checkpoints in adenoviral production. Cross-contamination and E1A. PLoS One 6, e23160
-
(2011)
PLoS One
, vol.6
-
-
Haeussler, D.J.1
Evangelista, A.M.2
Burgoyne, J.R.3
Cohen, R.A.4
Bachschmid, M.M.5
Pimental, D.R.6
-
22
-
-
84865441108
-
Redox regulation of SERCA2 is required for vascular endothelial growth factor-induced signaling and endothelial cell migration
-
Evangelista, A. M., Thompson, M. D., Weisbrod, R. M., Pimental, D. R., Tong, X., Bolotina, V. M., and Cohen, R. A. (2012) Redox regulation of SERCA2 is required for vascular endothelial growth factor-induced signaling and endothelial cell migration. Antioxid. Redox. Signal. 17, 1099-1108
-
(2012)
Antioxid. Redox. Signal.
, vol.17
, pp. 1099-1108
-
-
Evangelista, A.M.1
Thompson, M.D.2
Weisbrod, R.M.3
Pimental, D.R.4
Tong, X.5
Bolotina, V.M.6
Cohen, R.A.7
-
23
-
-
0033541687
-
Rapid assay for nitric oxide synthase using thin-layer chromatography
-
DOI 10.1006/abio.1999.4013
-
Kumar, V. B., Bernardo, A. E., Alshaher, M. M., Buddhiraju, M., Purushothaman, R., and Morley, J. E. (1999) Rapid assay for nitric oxide synthase using thin-layer chromatography. Anal. Biochem. 269, 17-20 (Pubitemid 29174257)
-
(1999)
Analytical Biochemistry
, vol.269
, Issue.1
, pp. 17-20
-
-
Kumar, V.B.1
Bernardo, A.E.2
Alshaher, M.M.3
Buddhiraju, M.4
Purushothaman, R.5
Morley, J.E.6
-
24
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
Dimmeler, S., Fleming, I., Fisslthaler, B., Hermann, C., Busse, R., and Zeiher, A. M. (1999) Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399, 601-605
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
Hermann, C.4
Busse, R.5
Zeiher, A.M.6
-
25
-
-
3142705856
-
Targeting of endothelial nitric-oxide synthase to the cytoplasmic face of the Golgi complex or plasma membrane regulates Akt- versus calcium-dependent mechanisms for nitric oxide release
-
DOI 10.1074/jbc.M402155200
-
Fulton, D., Babbitt, R., Zoellner, S., Fontana, J., Acevedo, L., McCabe, T. J., Iwakiri, Y., and Sessa, W. C. (2004) Targeting of endothelial nitric-oxide synthase to the cytoplasmic face of the Golgi complex or plasma membrane regulates Akt- versus calcium-dependent mechanisms for nitric oxide release. J. Biol. Chem. 279, 30349-30357 (Pubitemid 38937962)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.29
, pp. 30349-30357
-
-
Fulton, D.1
Babbitt, R.2
Zoellner, S.3
Fontana, J.4
Acevedo, L.5
McCabe, T.J.6
Iwakiri, Y.7
Sessa, W.C.8
-
26
-
-
33846392950
-
Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation
-
DOI 10.1016/j.yjmcc.2006.05.023, PII S0022282806005888
-
Mount, P. F., Kemp, B. E., and Power, D. A. (2007) Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation. J. Mol. Cell Cardiol. 42, 271-279 (Pubitemid 46135596)
-
(2007)
Journal of Molecular and Cellular Cardiology
, vol.42
, Issue.2
, pp. 271-279
-
-
Mount, P.F.1
Kemp, B.E.2
Power, D.A.3
-
27
-
-
0041631006
-
Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates nitric oxide-induced endothelial cell migration and angiogenesis
-
DOI 10.1128/MCB.23.16.5726-5737.2003
-
Kawasaki, K., Smith, R. S., Jr., Hsieh, C. M., Sun, J., Chao, J., and Liao, J. K. (2003) Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates nitric oxide-induced endothelial cell migration and angiogenesis. Mol. Cell Biol. 23, 5726-5737 (Pubitemid 36951336)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.16
, pp. 5726-5737
-
-
Kawasaki, K.1
Smith Jr., R.S.2
Hsieh, C.-M.3
Sun, J.4
Chao, J.5
Liao, J.K.6
-
28
-
-
78449231585
-
PKG-I inhibition attenuates vascular endothelial growth factor-stimulated angiogenesis
-
Koika, V., Zhou, Z., Vasileiadis, I., Roussos, C., Finetti, F., Monti, M., Morbidelli, L., and Papapetropoulos, A. (2010) PKG-I inhibition attenuates vascular endothelial growth factor-stimulated angiogenesis. Vascul. Pharmacol. 53, 215-222
-
(2010)
Vascul. Pharmacol.
, vol.53
, pp. 215-222
-
-
Koika, V.1
Zhou, Z.2
Vasileiadis, I.3
Roussos, C.4
Finetti, F.5
Monti, M.6
Morbidelli, L.7
Papapetropoulos, A.8
-
29
-
-
77951913833
-
The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins
-
Rocks, O., Gerauer, M., Vartak, N., Koch, S., Huang, Z. P., Pechlivanis, M., Kuhlmann, J., Brunsveld, L., Chandra, A., Ellinger, B., Waldmann, H., and Bastiaens, P. I. (2010) The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins. Cell 141, 458-471
-
(2010)
Cell
, vol.141
, pp. 458-471
-
-
Rocks, O.1
Gerauer, M.2
Vartak, N.3
Koch, S.4
Huang, Z.P.5
Pechlivanis, M.6
Kuhlmann, J.7
Brunsveld, L.8
Chandra, A.9
Ellinger, B.10
Waldmann, H.11
Bastiaens, P.I.12
-
30
-
-
20144375061
-
An acylation cycle regulates localization and activity of palmitoylated ras isoforms
-
DOI 10.1126/science.1105654
-
Rocks, O., Peyker, A., Kahms, M., Verveer, P. J., Koerner, C., Lumbierres, M., Kuhlmann, J., Waldmann, H., Wittinghofer, A., and Bastiaens, P. I. (2005) An acylation cycle regulates localization and activity of palmitoylated Ras isoforms. Science 307, 1746-1752 (Pubitemid 40388611)
-
(2005)
Science
, vol.307
, Issue.5716
, pp. 1746-1752
-
-
Rocks, O.1
Peyker, A.2
Kahms, M.3
Verveer, P.J.4
Koerner, C.5
Lumbierres, M.6
Kuhlmann, J.7
Waldmann, H.8
Wittinghofer, A.9
Bastiaens, P.I.H.10
-
31
-
-
79952263402
-
Compartmentalized Ras proteins transform NIH 3T3 cells with different efficiencies
-
Cheng, C. M., Li, H., Gasman, S., Huang, J., Schiff, R., and Chang, E. C. (2011) Compartmentalized Ras proteins transform NIH 3T3 cells with different efficiencies. Mol. Cell Biol. 31, 983-997
-
(2011)
Mol. Cell Biol.
, vol.31
, pp. 983-997
-
-
Cheng, C.M.1
Li, H.2
Gasman, S.3
Huang, J.4
Schiff, R.5
Chang, E.C.6
-
32
-
-
23144455311
-
Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration
-
DOI 10.1038/ncb1283
-
Rajalingam, K., Wunder, C., Brinkmann, V., Churin, Y., Hekman, M., Sievers, C., Rapp, U. R., and Rudel, T. (2005) Prohibitin is required for Rasinduced Raf-MEK-ERK activation and epithelial cell migration. Nat. Cell Biol. 7, 837-843 (Pubitemid 41079057)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.8
, pp. 837-843
-
-
Rajalingam, K.1
Wunder, C.2
Brinkmann, V.3
Churin, Y.4
Hekman, M.5
Sievers, C.6
Rapp, U.R.7
Rudel, T.8
-
33
-
-
0035136213
-
Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development
-
DOI 10.1128/MCB.21.5.1444-1452.2001
-
Esteban, L. M., Vicario-Abejón, C., Fernández-Salguero, P., Fernández-Medarde, A., Swaminathan, N., Yienger, K., Lopez, E., Malumbres, M., McKay, R., Ward, J. M., Pellicer, A., and Santos, E. (2001) Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development. Mol. Cell. Biol. 21, 1444-1452 (Pubitemid 32156364)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.5
, pp. 1444-1452
-
-
Esteban, L.M.1
Vicario-Abejon, C.2
Fernandez-Salguero, P.3
Fernandez-Medarde, A.4
Swaminathan, N.5
Yienger, K.6
Lopez, E.7
Malumbres, M.8
McKay, R.9
Ward, J.M.10
Pellicer, A.11
Santos, E.12
-
34
-
-
42049112366
-
+ vascular progenitor cells
-
DOI 10.1083/jcb.200709127
-
Kawasaki, K., Watabe, T., Sase, H., Hirashima, M., Koide, H., Morishita, Y., Yuki, K., Sasaoka, T., Suda, T., Katsuki, M., Miyazono, K., and Miyazawa, K. (2008) Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells. J. Cell Biol. 181, 131-141 (Pubitemid 351519770)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.1
, pp. 131-141
-
-
Kawasaki, K.1
Watabe, T.2
Sase, H.3
Hirashima, M.4
Koide, H.5
Morishita, Y.6
Yuki, K.7
Sasaoka, T.8
Suda, T.9
Katsuki, M.10
Miyazono, K.11
Miyazawa, K.12
-
35
-
-
0038137626
-
High density lipoprotein-induced angiogenesis requires the activation of Ras/MAP kinase in human coronary artery endothelial cells
-
DOI 10.1161/01.ATV.0000066134.79956.58
-
Miura, S., Fujino, M., Matsuo, Y., Kawamura, A., Tanigawa, H., Nishikawa, H., and Saku, K. (2003) High density lipoprotein-induced angiogenesis requires the activation of Ras/MAP kinase in human coronary artery endothelial cells. Arterioscler. Thromb. Vasc. Biol. 23, 802-808 (Pubitemid 36566169)
-
(2003)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.23
, Issue.5
, pp. 802-808
-
-
Miura, S.-I.1
Fujino, M.2
Matsuo, Y.3
Kawamura, A.4
Tanigawa, H.5
Nishikawa, H.6
Saku, K.7
-
36
-
-
77953770159
-
The farnesyltransferase inhibitor LB42708 suppresses vascular endothelial growth factor-induced angiogenesis by inhibiting ras-dependent mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signal pathways
-
Kim, C. K., Choi, Y. K., Lee, H., Ha, K. S., Won, M. H., Kwon, Y. G., and Kim, Y. M. (2010) The farnesyltransferase inhibitor LB42708 suppresses vascular endothelial growth factor-induced angiogenesis by inhibiting ras-dependent mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signal pathways. Mol. Pharmacol. 78, 142-150
-
(2010)
Mol. Pharmacol.
, vol.78
, pp. 142-150
-
-
Kim, C.K.1
Choi, Y.K.2
Lee, H.3
Ha, K.S.4
Won, M.H.5
Kwon, Y.G.6
Kim, Y.M.7
-
37
-
-
0033118228
-
VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells
-
Takahashi, T., Ueno, H., and Shibuya, M. (1999) VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells. Oncogene 18, 2221-2230 (Pubitemid 29186923)
-
(1999)
Oncogene
, vol.18
, Issue.13
, pp. 2221-2230
-
-
Takahashi, T.1
Ueno, H.2
Shibuya, M.3
-
38
-
-
0034681392
-
Utilization of distinct signaling pathways by receptors for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation
-
DOI 10.1074/jbc.275.7.5096
-
Wu, L. W., Mayo, L. D., Dunbar, J. D., Kessler, K. M., Baerwald, M. R., Jaffe, E. A., Wang, D., Warren, R. S., and Donner, D. B. (2000) Utilization of distinct signaling pathways by receptors for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation. J. Biol. Chem. 275, 5096-5103 (Pubitemid 30108910)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.7
, pp. 5096-5103
-
-
Wu, L.-W.1
Mayo, L.D.2
Dunbar, J.D.3
Kessler, K.M.4
Baerwald, M.R.5
Jaffe, E.A.6
Wang, D.7
Warren, R.S.8
Donner, D.B.9
-
39
-
-
34249026448
-
Binding of Ras to Phosphoinositide 3-Kinase p110α Is Required for Ras- Driven Tumorigenesis in Mice
-
DOI 10.1016/j.cell.2007.03.051, PII S009286740700520X
-
Gupta, S., Ramjaun, A. R., Haiko, P., Wang, Y., Warne, P. H., Nicke, B., Nye, E., Stamp, G., Alitalo, K., and Downward, J. (2007) Binding of ras to phosphoinositide 3-kinase p110α is required for ras-driven tumorigenesis in mice. Cell 129, 957-968 (Pubitemid 46802703)
-
(2007)
Cell
, vol.129
, Issue.5
, pp. 957-968
-
-
Gupta, S.1
Ramjaun, A.R.2
Haiko, P.3
Wang, Y.4
Warne, P.H.5
Nicke, B.6
Nye, E.7
Stamp, G.8
Alitalo, K.9
Downward, J.10
-
40
-
-
0036899189
-
Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: Role of PI3K, PKC and PLC pathways
-
DOI 10.1038/sj.bjp.0704956
-
Gélinas, D. S., Bernatchez, P. N., Rollin, S., Bazan, N. G., and Sirois, M. G. (2002) Immediate and delayed VEGF-mediated NO synthesis in endothelial cells. Role of PI3K, PKC and PLC pathways. Br. J. Pharmacol. 137, 1021-1030 (Pubitemid 35440742)
-
(2002)
British Journal of Pharmacology
, vol.137
, Issue.7
, pp. 1021-1030
-
-
Gelinas, D.S.1
Bernatchez, P.N.2
Rollin, S.3
Bazan, N.G.4
Sirois, M.G.5
-
41
-
-
0141885307
-
Receptor-regulated dynamic interaction between endothelial nitric oxide synthase and calmodulin revealed by fluorescence resonance energy transfer in living cells
-
DOI 10.1021/bi035066w
-
Jobin, C. M., Chen, H., Lin, A. J., Yacono, P. W., Igarashi, J., Michel, T., and Golan, D. E. (2003) Receptor-regulated dynamic interaction between endothelial nitric oxide synthase and calmodulin revealed by fluorescence resonance energy transfer in living cells. Biochemistry 42, 11716-11725 (Pubitemid 37243632)
-
(2003)
Biochemistry
, vol.42
, Issue.40
, pp. 11716-11725
-
-
Jobin, C.M.1
Chen, H.2
Lin, A.J.3
Yacono, P.W.4
Igarashi, J.5
Michel, T.6
Golan, D.E.7
-
42
-
-
0037131346
-
Subcellular targeting and agonist-induced site-specific phosphorylation of endothelial nitric-oxide synthase
-
DOI 10.1074/jbc.M207299200
-
Gonzalez, E., Kou, R., Lin, A. J., Golan, D. E., and Michel, T. (2002) Subcellular targeting and agonist-induced site-specific phosphorylation of endothelial nitric-oxide synthase. J. Biol. Chem. 277, 39554-39560 (Pubitemid 35190934)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.42
, pp. 39554-39560
-
-
Gonzalez, E.1
Kou, R.2
Lin, A.J.3
Golan, D.E.4
Michel, T.5
-
43
-
-
33845607123
-
Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling
-
DOI 10.1038/nature05269, PII NATURE05269
-
Daniels, M. A., Teixeiro, E., Gill, J., Hausmann, B., Roubaty, D., Holmberg, K., Werlen, G., Holländer, G. A., Gascoigne, N. R., and Palmer, E. (2006) Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling. Nature 444, 724-729 (Pubitemid 44949596)
-
(2006)
Nature
, vol.444
, Issue.7120
, pp. 724-729
-
-
Daniels, M.A.1
Teixeiro, E.2
Gill, J.3
Hausmann, B.4
Roubaty, D.5
Holmberg, K.6
Werlen, G.7
Hollander, G.A.8
Gascoigne, N.R.J.9
Palmer, E.10
-
44
-
-
84859422221
-
PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus
-
Jin, T., Ding, Q., Huang, H., Xu, D., Jiang, Y., Zhou, B., Li, Z., Jiang, X., He, J., Liu, W., Zhang, Y., Pan, Y., Wang, Z., Thomas, W. G., and Chen, Y. (2012) PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus. Cell Res. 22, 661-676
-
(2012)
Cell Res.
, vol.22
, pp. 661-676
-
-
Jin, T.1
Ding, Q.2
Huang, H.3
Xu, D.4
Jiang, Y.5
Zhou, B.6
Li, Z.7
Jiang, X.8
He, J.9
Liu, W.10
Zhang, Y.11
Pan, Y.12
Wang, Z.13
Thomas, W.G.14
Chen, Y.15
-
45
-
-
33845960772
-
Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking
-
DOI 10.1073/pnas.0605907103
-
Iwakiri, Y., Satoh, A., Chatterjee, S., Toomre, D. K., Chalouni, C. M., Fulton, D., Groszmann, R. J., Shah, V. H., and Sessa, W. C. (2006) Nitric oxide synthase generates nitric oxide locally to regulate compartmentalized protein S-nitrosylation and protein trafficking. Proc. Natl. Acad. Sci. U.S.A. 103, 19777-19782 (Pubitemid 46037507)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.52
, pp. 19777-19782
-
-
Iwakiri, Y.1
Satoh, A.2
Chatterjee, S.3
Toomre, D.K.4
Chalouni, C.M.5
Fulton, D.6
Groszmann, R.J.7
Shah, V.H.8
Sessa, W.C.9
-
46
-
-
0041488671
-
Phospholipase Cγ activates Ras on the Golgi apparatus by means of Ras-GRP1
-
Bivona, T. G., Pérez De Castro, I., Ahearn, I. M., Grana, T. M., Chiu, V. K., Lockyer, P. J., Cullen, P. J., Pellicer, A., Cox, A. D., and Philips, M. R. (2003) Phospholipase Cγ activates Ras on the Golgi apparatus by means of Ras-GRP1. Nature 424, 694-698
-
(2003)
Nature
, vol.424
, pp. 694-698
-
-
Bivona, T.G.1
Pérez De Castro, I.2
Ahearn, I.M.3
Grana, T.M.4
Chiu, V.K.5
Lockyer, P.J.6
Cullen, P.J.7
Pellicer, A.8
Cox, A.D.9
Philips, M.R.10
|