High density lipoprotein-induced angiogenesis requires the activation of Ras/MAP kinase in human coronary artery endothelial cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 23, Issue 5, 2003, Pages 802-808

  Miura, Shin ichiro ^a   Fujino, Masahiro ^b   Matsuo, Yoshino ^b   Kawamura, Akira ^b   Tanigawa, Hiroyuki ^b   Nishikawa, Hiroaki ^b   Saku, Keijiro ^b  

^a FUKUOKA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

High density lipoprotein; Human coronary artery endothelial cells; Mitogen activated protein kinase; Ras

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; G PROTEIN COUPLED RECEPTOR; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PERTUSSIS TOXIN; PROTEIN P42; PROTEIN P44; RAS PROTEIN; SYNAPTOPHYSIN;

ANGIOGENESIS; ARTERY ENDOTHELIUM; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CORONARY ARTERY; DOSE RESPONSE; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MODEL; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

CELLS, CULTURED; CORONARY VESSELS; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; HUMANS; IMIDAZOLES; LIPOPROTEINS, HDL; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NEOVASCULARIZATION, PHYSIOLOGIC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PERTUSSIS TOXIN; PROTO-ONCOGENE PROTEINS P21(RAS); PYRIDINES;

EID: 0038137626     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000066134.79956.58     Document Type: Article

References (27)

1. Gordon DJ, Rifkind BM. High-density lipoprotein: the clinical implicafions of recent studies. N Engl J Med. 1989;321:1311-1316.
2. von Eckardstein A, Nofer J-R, Assmann G. Acceleration of reverse cholesterol transport. Curr Opin Cardiol. 2000;15:348-354.
3. Tamagaki T, Sawada S, Imamura H, Tada Y, Yamasaki S, Toratani A, Sato T, Komatsu S, Akamatsu N, Yamagami M, Kobayashi K. Kato K, Yamamoto K, Shirai K, Yamada K, Higaki T, Nakagawa K, Tsuji H, Nakagawa M. Effects of high-density lipoproteins on intracellular pH and proliferation of human vascular endothelial cells. Atherosclerosis. 1996; 123:73-82.
4. Darbon JM, Tournier JF. Possible role of protein phosphorylation in the mitogenic effect of high density lipoproteins on cultured vascular endothelial cells. J Biol Chem. 1986;261:8002-8008.
5. Sugano M, Tsuchida K, Makino N. High-density lipoproteins protect endothelial cells from tumor necrosis factor-α-induced apoptosis. Biochem Biophys Res Commun. 2000;272:872-876.
6. Dimmeler S, Zeiher AM. Endothelial cell apoptosis in angiogenesis and vessel regression. Circ Res. 2000;87:434-439.
7. Isner JM, Asahara T. Angiogenesis and vasculogenesis as therapeutic strategies for postnatal neovascularization. J Clin Invest. 1999;103: 1231-1236.
8. Rak J, Kerbel RS. Ras regulation of vascular endothelial growth factor and angiogenesis. Methods Enzymol. 2001;333:267-283.
9. Meadows KN, Bryant P, Pumiglia K. Vascular endothelial growth factor induction of the angiogenic phenotype requires Ras activafion. J Biol Chem. 2001;276:49289-29298.
10. Kahlon R, Shapero J, Gotlieb AI. Angiogenesis in atherosclerosis. Can J Cardiol. 1992;8:60-64.
11. Kleinman HK, McGarvey ML, Hassell JR, Star VL, Cannon FB, Laurie GW, Martin GR. Basement membrane complexes with biological activity. Biochemistry. 1986;25:312-318.
12. Miura S, Karnik SS. Ligand-independent signals from angiotensin II type 2 receptor induce apoptosis. EMBO J. 2000;19:4026-4035.
13. Sun J, Qian Y, Hamilton AD, Sebti S M. Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts. Oncogene. 1998;16: 1467-1473.
14. Roovers K, Assoian RK. Integrating the MAP kinase signal into the G1 phase cell cycle machinery. Bioessays. 2000;22:818-826.
15. Pang L, Sawada T, Decker SJ, Saltiel AR. Inhibition of MAP kinase blocks the differentiation of PC-12 cells induced by nerve growth factor. J Biol Chem. 1995;270;13585-13588.
16. a. Rousseau S, Houle F, Landry J, Huot J. p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells. Oncogene. 1997;15:2169-2177.
17. Kimura T, Sato K, Kuwabara A, Tomura H, Ishiwara M, Kobayashi I, Ui M, Okajima F. Sphingosine 1-phosphate may be a major component of plasma lipoproteins responsible for the cytoprotective actions in human umbilical vein endothelial cells. J Biol Chem. 2001;276:31780-31785.
18. Nofer JR, Levkau B, Wolinska I, Junker R, Fobker M, von Eckardstein A, Seedorf U, Assmann G. Suppression of endothelial cell apoptosis by high density lipoproteins (HDL) and HDL-associated lysosphingolipids. J Biol Chem. 2001;276:34480-34485.
19. Nofer JR, Junker R, Pulawski E, Fobker M, Levkau B, von Eckardstein A, Seedorf U, Assmann G, Walter M. High density lipoproteins induce cell cycle entry in vascular smooth muscle cells via mitogen activated protein kinase-dependent pathway. Thromb Haemost. 2001;85:730-735.
20. Ashby DT, Rye K. Factors influencing the ability of HDL to inhibit expression of vascular cell adhesion molecule-1 in endothelial cells. Arterioscler Thromb Vasc Biol. 1998;18:1450-1455.
21. Suc I, Escargueil-Blanc I, Troly M, Salvayre R, Negre-Salvayre A. HDL and ApoA prevent cell death of endothelial cells induced by oxidized LDL. Arterioscler Thromb Vasc Biol. 1997;17:2158-2166.
22. Isner JM, Losordo DW. Therapeutic angiogenesis for heart failure. Nat Med. 1999;5:491-492.
23. Kahlon R, Shapero J, Gotlieb AI. Angiogenesis in atherosclerosis. Can J Cardiol. 1992;8:60-64.
24. Kerbel RS, Viloria-Petit A, Klement G, Rak J. "Accidental" anti-angiogenic drugs: anti-oncogene directed signal transduction inhibitors and conventional chemotherapeutic agents as examples. Eur J Cancer. 2000;36:1248-1257.
25. Eliceiri BP, Paul R, Schwartzberg PL, Hood JD, Leng J, Cheresh DA. Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. Mol Cell. 1999;4:915-924.
26. Kimura T, Sato K, Kuwabara A, Tomura H, Ishiwara M, Kobayashi I, Ui M, Okajima M. Sphingosine 1-phosphate may be a major component of plasma lipoproteins responsible for the cytoprotective actions in human umbilical vein endothelial cells. J Biol Chem. 2001;276:31780-31785.
27. Uittenbogaard A, Shaul PW, Yuhanna IS, Blair A, Smart EJ. High density lipoprotein prevents oxidized low density lipoprotein-induced inhibition of endothelial nitric-oxide synthase localization and activation in caveolae. J Biol Chem. 2000;275:11278-11283.