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Volumn 54, Issue 4, 2013, Pages 807-812

Regulatory role of hypoxia inducible factor in the biological behavior of nucleus pulposus cells

Author keywords

Hypoxia inducible factor; Intervertebral disc degeneration; Nucleus pulposus

Indexed keywords

FAS ANTIGEN; FAS LIGAND; GALECTIN 3; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 3; GLYCOSAMINOGLYCAN; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; VASCULOTROPIN;

EID: 84878242565     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2013.54.4.807     Document Type: Article
Times cited : (22)

References (65)
  • 1
    • 84864971761 scopus 로고    scopus 로고
    • Cost-effectiveness of a classification-based system for sub-acute and chronic low back pain
    • Apeldoorn AT, Bosmans JE, Ostelo RW, de Vet HC, van Tulder MW. Cost-effectiveness of a classification-based system for sub-acute and chronic low back pain. Eur Spine J 2012;21:1290-300.
    • (2012) Eur Spine J , vol.21 , pp. 1290-1300
    • Apeldoorn, A.T.1    Bosmans, J.E.2    Ostelo, R.W.3    de Vet, H.C.4    van Tulder, M.W.5
  • 2
    • 80052522854 scopus 로고    scopus 로고
    • Cost-effectiveness of guideline-endorsed treatments for low back pain: A systematic review
    • Lin CW, Haas M, Maher CG, Machado LA, van Tulder MW. Cost-effectiveness of guideline-endorsed treatments for low back pain: a systematic review. Eur Spine J 2011;20:1024-38.
    • (2011) Eur Spine J , vol.20 , pp. 1024-1038
    • Lin, C.W.1    Haas, M.2    Maher, C.G.3    McHado, L.A.4    van Tulder, M.W.5
  • 4
    • 33845360925 scopus 로고    scopus 로고
    • Prevalence, risk factors, and preference-based health states of low back pain in a Turkish population
    • Oksuz E. Prevalence, risk factors, and preference-based health states of low back pain in a Turkish population. Spine (Phila Pa 1976) 2006;31:E968-72.
    • (2006) Spine (Phila Pa 1976) , vol.31
    • Oksuz, E.1
  • 5
    • 84862855802 scopus 로고    scopus 로고
    • Ex vivo observation of human intervertebral disc tissue and cells isolated from degenerated intervertebral discs
    • Ciapetti G, Granchi D, Devescovi V, Leonardi E, Greggi T, Di Silvestre M, et al. Ex vivo observation of human intervertebral disc tissue and cells isolated from degenerated intervertebral discs. Eur Spine J 2012;21 Suppl 1:S10-9.
    • (2012) Eur Spine J , vol.21 , Issue.SUPPL. 1
    • Ciapetti, G.1    Granchi, D.2    Devescovi, V.3    Leonardi, E.4    Greggi, T.5    Di Silvestre, M.6
  • 6
    • 36248938590 scopus 로고    scopus 로고
    • The association of the activation-inducible tumor necrosis factor receptor and ligand with lumbar disc herniation
    • Park MS, Lee HM, Hahn SB, Moon SH, Kim YT, Lee CS, et al. The association of the activation-inducible tumor necrosis factor receptor and ligand with lumbar disc herniation. Yonsei Med J 2007;48:839-46.
    • (2007) Yonsei Med J , vol.48 , pp. 839-846
    • Park, M.S.1    Lee, H.M.2    Hahn, S.B.3    Moon, S.H.4    Kim, Y.T.5    Lee, C.S.6
  • 7
    • 0036865325 scopus 로고    scopus 로고
    • Disc morphology in health and disease
    • Roberts S. Disc morphology in health and disease. Biochem Soc Trans 2002;30(Pt 6):864-9.
    • (2002) Biochem Soc Trans , vol.30 , Issue.PART 6 , pp. 864-869
    • Roberts, S.1
  • 8
    • 0034802078 scopus 로고    scopus 로고
    • Stress analysis of the disc adjacent to interbody fusion in lumbar spine
    • Chen CS, Cheng CK, Liu CL, Lo WH. Stress analysis of the disc adjacent to interbody fusion in lumbar spine. Med Eng Phys 2001;23:483-91.
    • (2001) Med Eng Phys , vol.23 , pp. 483-491
    • Chen, C.S.1    Cheng, C.K.2    Liu, C.L.3    Lo, W.H.4
  • 9
    • 21244454058 scopus 로고    scopus 로고
    • Structure and function of the notochord: An essential organ for chordate development
    • Stemple DL. Structure and function of the notochord: an essential organ for chordate development. Development 2005;132:2503-12.
    • (2005) Development , vol.132 , pp. 2503-2512
    • Stemple, D.L.1
  • 10
    • 0035989142 scopus 로고    scopus 로고
    • Phenotypic characteristics of the nucleus pulposus: Expression of hypoxia inducing factor-1, glucose transporter-1 and MMP-2
    • Rajpurohit R, Risbud MV, Ducheyne P, Vresilovic EJ, Shapiro IM. Phenotypic characteristics of the nucleus pulposus: expression of hypoxia inducing factor-1, glucose transporter-1 and MMP-2. Cell Tissue Res 2002;308:401-7.
    • (2002) Cell Tissue Res , vol.308 , pp. 401-407
    • Rajpurohit, R.1    Risbud, M.V.2    Ducheyne, P.3    Vresilovic, E.J.4    Shapiro, I.M.5
  • 11
    • 70450170088 scopus 로고    scopus 로고
    • Nucleus pulposus tissue engineering: A brief review
    • Yang X, Li X. Nucleus pulposus tissue engineering: a brief review. Eur Spine J 2009;18:1564-72.
    • (2009) Eur Spine J , vol.18 , pp. 1564-1572
    • Yang, X.1    Li, X.2
  • 12
    • 79956289366 scopus 로고    scopus 로고
    • Stand-alone cage for posterior lumbar interbody fusion in the treatment of high-degree degenerative disc disease: Design of a new device for an "old" technique. A prospective study on a series of 116 patients
    • Costa F, Sassi M, Ortolina A, Cardia A, Assietti R, Zerbi A, et al. Stand-alone cage for posterior lumbar interbody fusion in the treatment of high-degree degenerative disc disease: design of a new device for an "old" technique. A prospective study on a series of 116 patients. Eur Spine J 2011;20 Suppl 1:S46-56.
    • (2011) Eur Spine J , vol.20 , Issue.SUPPL. 1
    • Costa, F.1    Sassi, M.2    Ortolina, A.3    Cardia, A.4    Assietti, R.5    Zerbi, A.6
  • 13
    • 0016712132 scopus 로고
    • Growth of human intervertebral discs and vertebral bodies
    • Taylor JR. Growth of human intervertebral discs and vertebral bodies. J Anat 1975;120(Pt 1):49-68.
    • (1975) J Anat , vol.120 , Issue.PART 1 , pp. 49-68
    • Taylor, J.R.1
  • 14
    • 0027466510 scopus 로고
    • Lymph and blood supply of the human intervertebral disc. Cadaver study of correlations to discitis
    • Rudert M, Tillmann B. Lymph and blood supply of the human intervertebral disc. Cadaver study of correlations to discitis. Acta Orthop Scand 1993;64:37-40.
    • (1993) Acta Orthop Scand , vol.64 , pp. 37-40
    • Rudert, M.1    Tillmann, B.2
  • 15
    • 84860864145 scopus 로고    scopus 로고
    • Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: Distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia
    • Fujita N, Markova D, Anderson DG, Chiba K, Toyama Y, Shapiro IM, et al. Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia. J Biol Chem 2012; 287:16975-86.
    • (2012) J Biol Chem , vol.287 , pp. 16975-16986
    • Fujita, N.1    Markova, D.2    Anderson, D.G.3    Chiba, K.4    Toyama, Y.5    Shapiro, I.M.6
  • 16
    • 0036865353 scopus 로고    scopus 로고
    • The role of the physicochemical environment in determining disc cell behaviour
    • Urban JP. The role of the physicochemical environment in determining disc cell behaviour. Biochem Soc Trans 2002;30(Pt 6):858-64.
    • (2002) Biochem Soc Trans , vol.30 , Issue.PART 6 , pp. 858-864
    • Urban, J.P.1
  • 18
    • 41049084437 scopus 로고    scopus 로고
    • Expression of glucose transporters GLUT-1, GLUT-3, GLUT-9 and HIF-1alpha in normal and degenerate human intervertebral disc
    • Richardson SM, Knowles R, Tyler J, Mobasheri A, Hoyland JA. Expression of glucose transporters GLUT-1, GLUT-3, GLUT-9 and HIF-1alpha in normal and degenerate human intervertebral disc. Histochem Cell Biol 2008;129:503-11.
    • (2008) Histochem Cell Biol , vol.129 , pp. 503-511
    • Richardson, S.M.1    Knowles, R.2    Tyler, J.3    Mobasheri, A.4    Hoyland, J.A.5
  • 19
    • 0032581277 scopus 로고    scopus 로고
    • Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
    • Carmeliet P, Dor Y, Herbert JM, Fukumura D, Brusselmans K, Dewerchin M, et al. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 1998;394:485-90.
    • (1998) Nature , vol.394 , pp. 485-490
    • Carmeliet, P.1    Dor, Y.2    Herbert, J.M.3    Fukumura, D.4    Brusselmans, K.5    Dewerchin, M.6
  • 20
    • 0034901463 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology
    • Semenza GL. Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology. Trends Mol Med 2001;7:345-50.
    • (2001) Trends Mol Med , vol.7 , pp. 345-350
    • Semenza, G.L.1
  • 21
    • 0034006016 scopus 로고    scopus 로고
    • HIF-1: Mediator of physiological and pathophysiological responses to hypoxia
    • Semenza GL. HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 2000;88:1474-80.
    • (2000) J Appl Physiol , vol.88 , pp. 1474-1480
    • Semenza, G.L.1
  • 22
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
    • Semenza GL, Wang GL. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 1992;12:5447-54.
    • (1992) Mol Cell Biol , vol.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 23
    • 80053066607 scopus 로고    scopus 로고
    • Hypoxia is essential for bone-tendon junction healing: The molecular biological evidence
    • Zhao J, Zhang P, Qin L, Pan XH. Hypoxia is essential for bone-tendon junction healing: the molecular biological evidence. Int Orthop 2011;35:925-8.
    • (2011) Int Orthop , vol.35 , pp. 925-928
    • Zhao, J.1    Zhang, P.2    Qin, L.3    Pan, X.H.4
  • 24
    • 33646010313 scopus 로고    scopus 로고
    • Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: A metabolic adaptation to the intervertebral disc microenvironment
    • Risbud MV, Guttapalli A, Stokes DG, Hawkins D, Danielson KG, Schaer TP, et al. Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment. J Cell Biochem 2006;98:152-9.
    • (2006) J Cell Biochem , vol.98 , pp. 152-159
    • Risbud, M.V.1    Guttapalli, A.2    Stokes, D.G.3    Hawkins, D.4    Danielson, K.G.5    Schaer, T.P.6
  • 25
    • 57349102342 scopus 로고    scopus 로고
    • Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc
    • Agrawal A, Gajghate S, Smith H, Anderson DG, Albert TJ, Shapiro IM, et al. Cited2 modulates hypoxia-inducible factor-dependent expression of vascular endothelial growth factor in nucleus pulposus cells of the rat intervertebral disc. Arthritis Rheum 2008;58:3798-808.
    • (2008) Arthritis Rheum , vol.58 , pp. 3798-3808
    • Agrawal, A.1    Gajghate, S.2    Smith, H.3    Anderson, D.G.4    Albert, T.J.5    Shapiro, I.M.6
  • 26
    • 84856160786 scopus 로고    scopus 로고
    • HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc
    • Fujita N, Chiba K, Shapiro IM, Risbud MV. HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc. J Bone Miner Res 2012;27:401-12.
    • (2012) J Bone Miner Res , vol.27 , pp. 401-412
    • Fujita, N.1    Chiba, K.2    Shapiro, I.M.3    Risbud, M.V.4
  • 29
    • 34547763695 scopus 로고    scopus 로고
    • Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk
    • Agrawal A, Guttapalli A, Narayan S, Albert TJ, Shapiro IM, Risbud MV. Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk. Am J Physiol Cell Physiol 2007;293:C621-31.
    • (2007) Am J Physiol Cell Physiol , vol.293
    • Agrawal, A.1    Guttapalli, A.2    Narayan, S.3    Albert, T.J.4    Shapiro, I.M.5    Risbud, M.V.6
  • 30
    • 79959843998 scopus 로고    scopus 로고
    • Hypoxic regulation of β-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: Role of hypoxia-inducible factor proteins
    • Gogate SS, Nasser R, Shapiro IM, Risbud MV. Hypoxic regulation of β-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: role of hypoxia-inducible factor proteins. Arthritis Rheum 2011;63:1950-60.
    • (2011) Arthritis Rheum , vol.63 , pp. 1950-1960
    • Gogate, S.S.1    Nasser, R.2    Shapiro, I.M.3    Risbud, M.V.4
  • 31
    • 77956362994 scopus 로고    scopus 로고
    • Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: Possible implications in controlling dystrophic mineralization in the intervertebral disc
    • Skubutyte R, Markova D, Freeman TA, Anderson DG, Dion AS, Williams CJ, et al. Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: possible implications in controlling dystrophic mineralization in the intervertebral disc. Arthritis Rheum 2010;62:2707-15.
    • (2010) Arthritis Rheum , vol.62 , pp. 2707-2715
    • Skubutyte, R.1    Markova, D.2    Freeman, T.A.3    Anderson, D.G.4    Dion, A.S.5    Williams, C.J.6
  • 32
    • 19944399717 scopus 로고    scopus 로고
    • 6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia
    • Obach M, Navarro-Sabaté A, Caro J, Kong X, Duran J, Gómez M, et al. 6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia. J Biol Chem 2004;279:53562-70.
    • (2004) J Biol Chem , vol.279 , pp. 53562-53570
    • Obach, M.1    Navarro-Sabaté, A.2    Caro, J.3    Kong, X.4    Duran, J.5    Gómez, M.6
  • 33
    • 0035500503 scopus 로고    scopus 로고
    • Hypoxia: The tumor's gateway to progression along the angiogenic pathway
    • Brahimi-Horn C, Berra E, Pouysségur J. Hypoxia: the tumor's gateway to progression along the angiogenic pathway. Trends Cell Biol 2001;11:S32-6.
    • (2001) Trends Cell Biol , vol.11
    • Brahimi-Horn, C.1    Berra, E.2    Pouysségur, J.3
  • 34
    • 57349174991 scopus 로고    scopus 로고
    • Signaling in response to hypoxia and normoxia in the intervertebral disc
    • Boskey AL. Signaling in response to hypoxia and normoxia in the intervertebral disc. Arthritis Rheum 2008;58:3637-9.
    • (2008) Arthritis Rheum , vol.58 , pp. 3637-3639
    • Boskey, A.L.1
  • 35
    • 0036710591 scopus 로고    scopus 로고
    • Signal transduction to hypoxia-inducible factor 1
    • Semenza G. Signal transduction to hypoxia-inducible factor 1. Biochem Pharmacol 2002;64:993-8.
    • (2002) Biochem Pharmacol , vol.64 , pp. 993-998
    • Semenza, G.1
  • 37
    • 77950583159 scopus 로고    scopus 로고
    • Hypoxic regulation of nucleus pulposus cell survival: From niche to notch
    • Risbud MV, Schipani E, Shapiro IM. Hypoxic regulation of nucleus pulposus cell survival: from niche to notch. Am J Pathol 2010; 176:1577-83.
    • (2010) Am J Pathol , vol.176 , pp. 1577-1583
    • Risbud, M.V.1    Schipani, E.2    Shapiro, I.M.3
  • 38
    • 33847615147 scopus 로고    scopus 로고
    • Prolyl hydroxylase domain 2 protein suppresses hypoxia-induced endothelial cell proliferation
    • Takeda K, Fong GH. Prolyl hydroxylase domain 2 protein suppresses hypoxia-induced endothelial cell proliferation. Hypertension 2007;49:178-84.
    • (2007) Hypertension , vol.49 , pp. 178-184
    • Takeda, K.1    Fong, G.H.2
  • 39
    • 4644318828 scopus 로고    scopus 로고
    • Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor
    • Appelhoff RJ, Tian YM, Raval RR, Turley H, Harris AL, Pugh CW, et al. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor. J Biol Chem 2004;279:38458-65.
    • (2004) J Biol Chem , vol.279 , pp. 38458-38465
    • Appelhoff, R.J.1    Tian, Y.M.2    Raval, R.R.3    Turley, H.4    Harris, A.L.5    Pugh, C.W.6
  • 40
    • 44649175659 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-A is a survival factor for nucleus pulposus cells in the intervertebral disc
    • Fujita N, Imai J, Suzuki T, Yamada M, Ninomiya K, Miyamoto K, et al. Vascular endothelial growth factor-A is a survival factor for nucleus pulposus cells in the intervertebral disc. Biochem Biophys Res Commun 2008;372:367-72.
    • (2008) Biochem Biophys Res Commun , vol.372 , pp. 367-372
    • Fujita, N.1    Imai, J.2    Suzuki, T.3    Yamada, M.4    Ninomiya, K.5    Miyamoto, K.6
  • 41
    • 10444232467 scopus 로고    scopus 로고
    • Effect of nutrient deprivation on the viability of intervertebral disc cells
    • Bibby SR, Urban JP. Effect of nutrient deprivation on the viability of intervertebral disc cells. Eur Spine J 2004;13:695-701.
    • (2004) Eur Spine J , vol.13 , pp. 695-701
    • Bibby, S.R.1    Urban, J.P.2
  • 42
    • 0035584277 scopus 로고    scopus 로고
    • 2001 Volvo Award Winner in Basic Science Studies: Effect of nutrient supply on the viability of cells from the nucleus pulposus of the intervertebral disc
    • Horner HA, Urban JP. 2001 Volvo Award Winner in Basic Science Studies: effect of nutrient supply on the viability of cells from the nucleus pulposus of the intervertebral disc. Spine (Phila Pa 1976) 2001;26:2543-9.
    • (2001) Spine (Phila Pa 1976) , vol.26 , pp. 2543-2549
    • Horner, H.A.1    Urban, J.P.2
  • 43
    • 0035868674 scopus 로고    scopus 로고
    • Expression of Fas ligand and apoptosis of disc cells in herniated lumbar disc tissue
    • Park JB, Chang H, Kim KW. Expression of Fas ligand and apoptosis of disc cells in herniated lumbar disc tissue. Spine (Phila Pa 1976) 2001;26:618-21.
    • (2001) Spine (Phila Pa 1976) , vol.26 , pp. 618-621
    • Park, J.B.1    Chang, H.2    Kim, K.W.3
  • 44
    • 0033870111 scopus 로고    scopus 로고
    • Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses
    • Hsu DK, Yang RY, Pan Z, Yu L, Salomon DR, Fung-Leung WP, et al. Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses. Am J Pathol 2000;156: 1073-83.
    • (2000) Am J Pathol , vol.156 , pp. 1073-1083
    • Hsu, D.K.1    Yang, R.Y.2    Pan, Z.3    Yu, L.4    Salomon, D.R.5    Fung-Leung, W.P.6
  • 45
    • 83255162010 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF), VEGF receptors and their inhibitors for antiangiogenic tumor therapy
    • Takahashi S. Vascular endothelial growth factor (VEGF), VEGF receptors and their inhibitors for antiangiogenic tumor therapy. Biol Pharm Bull 2011;34:1785-8.
    • (2011) Biol Pharm Bull , vol.34 , pp. 1785-1788
    • Takahashi, S.1
  • 46
    • 80052327916 scopus 로고    scopus 로고
    • The effect of sustained compression on oxygen metabolic transport in the intervertebral disc decreases with degenerative changes
    • Malandrino A, Noailly J, Lacroix D. The effect of sustained compression on oxygen metabolic transport in the intervertebral disc decreases with degenerative changes. PLoS Comput Biol 2011; 7:e1002112.
    • (2011) PLoS Comput Biol , vol.7
    • Malandrino, A.1    Noailly, J.2    Lacroix, D.3
  • 48
    • 0028068606 scopus 로고
    • Transcriptional reg ulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
    • Semenza GL, Roth PH, Fang HM, Wang GL. Transcriptional reg ulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem 1994;269:23757-63.
    • (1994) J Biol Chem , vol.269 , pp. 23757-23763
    • Semenza, G.L.1    Roth, P.H.2    Fang, H.M.3    Wang, G.L.4
  • 49
    • 33644622570 scopus 로고    scopus 로고
    • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • Papandreou I, Cairns RA, Fontana L, Lim AL, Denko NC. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab 2006;3:187-97.
    • (2006) Cell Metab , vol.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 50
    • 0032524711 scopus 로고    scopus 로고
    • Alterations in GLUT1 and GLUT3 glucose transporter gene expression following unilateral hypoxia-ischemia in the immature rat brain
    • Vannucci SJ, Reinhart R, Maher F, Bondy CA, Lee WH, Vannucci RC, et al. Alterations in GLUT1 and GLUT3 glucose transporter gene expression following unilateral hypoxia-ischemia in the immature rat brain. Brain Res Dev Brain Res 1998;107:255-64.
    • (1998) Brain Res Dev Brain Res , vol.107 , pp. 255-264
    • Vannucci, S.J.1    Reinhart, R.2    Maher, F.3    Bondy, C.A.4    Lee, W.H.5    Vannucci, R.C.6
  • 54
    • 0036684509 scopus 로고    scopus 로고
    • Regional variations in the cellular matrix of the annulus fibrosus of the intervertebral disc
    • Bruehlmann SB, Rattner JB, Matyas JR, Duncan NA. Regional variations in the cellular matrix of the annulus fibrosus of the intervertebral disc. J Anat 2002;201:159-71.
    • (2002) J Anat , vol.201 , pp. 159-171
    • Bruehlmann, S.B.1    Rattner, J.B.2    Matyas, J.R.3    Duncan, N.A.4
  • 55
    • 4544272466 scopus 로고    scopus 로고
    • Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral disc
    • Le Maitre CL, Freemont AJ, Hoyland JA. Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral disc. J Pathol 2004;204:47-54.
    • (2004) J Pathol , vol.204 , pp. 47-54
    • Le Maitre, C.L.1    Freemont, A.J.2    Hoyland, J.A.3
  • 57
    • 33748946431 scopus 로고    scopus 로고
    • Nucleus pulposus glycosaminoglycan content is correlated with axial mechanics in rat lumbar motion segments
    • Boxberger JI, Sen S, Yerramalli CS, Elliott DM. Nucleus pulposus glycosaminoglycan content is correlated with axial mechanics in rat lumbar motion segments. J Orthop Res 2006;24:1906-15.
    • (2006) J Orthop Res , vol.24 , pp. 1906-1915
    • Boxberger, J.I.1    Sen, S.2    Yerramalli, C.S.3    Elliott, D.M.4
  • 58
    • 33646703312 scopus 로고    scopus 로고
    • Determinants of pathological mineralization
    • Kirsch T. Determinants of pathological mineralization. Curr Opin Rheumatol 2006;18:174-80.
    • (2006) Curr Opin Rheumatol , vol.18 , pp. 174-180
    • Kirsch, T.1
  • 59
    • 85028114403 scopus 로고    scopus 로고
    • Biomineralization and matrix vesicles in biology and pathology
    • Golub EE. Biomineralization and matrix vesicles in biology and pathology. Semin Immunopathol 2011;33:409-17.
    • (2011) Semin Immunopathol , vol.33 , pp. 409-417
    • Golub, E.E.1
  • 60
    • 63849198391 scopus 로고    scopus 로고
    • Calcification in the ovine intervertebral disc: A model of hydroxyapatite deposition disease
    • Melrose J, Burkhardt D, Taylor TK, Dillon CT, Read R, Cake M, et al. Calcification in the ovine intervertebral disc: a model of hydroxyapatite deposition disease. Eur Spine J 2009;18:479-89.
    • (2009) Eur Spine J , vol.18 , pp. 479-489
    • Melrose, J.1    Burkhardt, D.2    Taylor, T.K.3    Dillon, C.T.4    Read, R.5    Cake, M.6
  • 61
    • 0032996753 scopus 로고    scopus 로고
    • Ectopic calcification: Gathering hard facts about soft tissue mineralization
    • Giachelli CM. Ectopic calcification: gathering hard facts about soft tissue mineralization. Am J Pathol 1999;154:671-5.
    • (1999) Am J Pathol , vol.154 , pp. 671-675
    • Giachelli, C.M.1
  • 63
    • 33646672387 scopus 로고    scopus 로고
    • Role of the progressive ankylosis gene in cartilage mineralization
    • Zaka R, Williams CJ. Role of the progressive ankylosis gene in cartilage mineralization. Curr Opin Rheumatol 2006;18:181-6.
    • (2006) Curr Opin Rheumatol , vol.18 , pp. 181-186
    • Zaka, R.1    Williams, C.J.2
  • 65
    • 0141788321 scopus 로고    scopus 로고
    • Mutations in the amino terminus of ANKH in two US families with calcium pyrophosphate dihydrate crystal deposition disease
    • Williams CJ, Pendleton A, Bonavita G, Reginato AJ, Hughes AE, Peariso S, et al. Mutations in the amino terminus of ANKH in two US families with calcium pyrophosphate dihydrate crystal deposition disease. Arthritis Rheum 2003;48:2627-31.
    • (2003) Arthritis Rheum , vol.48 , pp. 2627-2631
    • Williams, C.J.1    Pendleton, A.2    Bonavita, G.3    Reginato, A.J.4    Hughes, A.E.5    Peariso, S.6


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