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Volumn 288, Issue 21, 2013, Pages 15098-15109

Metabolite profiling to characterize disease-related bacteria: Gluconate excretion by pseudomonas aeruginosa mutants and clinical isolates from cystic fibrosis patients

Author keywords

[No Author keywords available]

Indexed keywords

CATABOLITE REPRESSION; CENTRAL CARBON METABOLISMS; CYSTIC FIBROSIS SPUTUM; INTRACELLULAR METABOLITES; METABOLIC FOOTPRINTING; PSEUDOMONAS AERUGINOSA; RANDOM AMPLIFICATION OF POLYMORPHIC; TWO COMPONENT SYSTEMS;

EID: 84878239366     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.442814     Document Type: Article
Times cited : (36)

References (66)
  • 1
    • 37749013600 scopus 로고    scopus 로고
    • Cystic fibrosis
    • Davies, J. C., Alton, E. W., and Bush, A. (2007) Cystic fibrosis. BMJ 335, 1255-1259
    • (2007) BMJ , vol.335 , pp. 1255-1259
    • Davies, J.C.1    Alton, E.W.2    Bush, A.3
  • 2
    • 84859839030 scopus 로고    scopus 로고
    • Basic science for the chest physician. Pseudomonas aeruginosa and the cystic fibrosis airway
    • Williams, H. D., and Davies, J. C. (2012) Basic science for the chest physician. Pseudomonas aeruginosa and the cystic fibrosis airway. Thorax 67, 465-467
    • (2012) Thorax , vol.67 , pp. 465-467
    • Williams, H.D.1    Davies, J.C.2
  • 6
    • 0038699591 scopus 로고    scopus 로고
    • High-throughput classification of yeast mutants for functional genomics using metabolic footprinting
    • DOI 10.1038/nbt823
    • Allen, J., Davey, H. M., Broadhurst, D., Heald, J. K., Rowland, J. J., Oliver, S. G., and Kell, D. B. (2003) High-throughput classification of yeast mutants for functional genomics using metabolic footprinting. Nat. Biotechnol. 21, 692-696 (Pubitemid 36638098)
    • (2003) Nature Biotechnology , vol.21 , Issue.6 , pp. 692-696
    • Allen, J.1    Davey, H.M.2    Broadhurst, D.3    Heald, J.K.4    Rowland, J.J.5    Oliver, S.G.6    Kell, D.B.7
  • 8
    • 67049109139 scopus 로고    scopus 로고
    • Genomewide identification of genetic determinants of antimicrobial drug resistance in Pseudomonas aeruginosa
    • Dötsch, A., Becker, T., Pommerenke, C., Magnowska, Z., Jänsch, L., and Häussler, S. (2009) Genomewide identification of genetic determinants of antimicrobial drug resistance in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 53, 2522-2531
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 2522-2531
    • Dötsch, A.1    Becker, T.2    Pommerenke, C.3    Magnowska, Z.4    Jänsch, L.5    Häussler, S.6
  • 10
    • 67650863623 scopus 로고    scopus 로고
    • Connecting quorum sensing, c-di-GMP, pel polysaccharide, and biofilm formation in Pseudomonas aeruginosa through tyrosine phosphatase TpbA (PA3885)
    • Ueda, A., and Wood, T. K. (2009) Connecting quorum sensing, c-di-GMP, pel polysaccharide, and biofilm formation in Pseudomonas aeruginosa through tyrosine phosphatase TpbA (PA3885). PLoS Pathog. 5, e1000483
    • (2009) PLoS Pathog. , vol.5
    • Ueda, A.1    Wood, T.K.2
  • 13
    • 36549035760 scopus 로고    scopus 로고
    • Nutritional cues control Pseudomonas aeruginosa multicellular behavior in cystic fibrosis sputum
    • DOI 10.1128/JB.01138-07
    • Palmer, K. L., Aye, L. M., and Whiteley, M. (2007) Nutritional cues control Pseudomonas aeruginosa multicellular behavior in cystic fibrosis sputum. J. Bacteriol. 189, 8079-8087 (Pubitemid 350178919)
    • (2007) Journal of Bacteriology , vol.189 , Issue.22 , pp. 8079-8087
    • Palmer, K.L.1    Aye, L.M.2    Whiteley, M.3
  • 14
    • 0025100949 scopus 로고
    • The rpoN gene product of Pseudomonas aeruginosa is required for expression of diverse genes, including the flagellin gene
    • Totten, P. A., Lara, J. C., and Lory, S. (1990) The rpoN gene product of Pseudomonas aeruginosa is required for expression of diverse genes, including the flagellin gene. J. Bacteriol. 172, 389-396 (Pubitemid 20016858)
    • (1990) Journal of Bacteriology , vol.172 , Issue.1 , pp. 389-396
    • Totten, P.A.1    Cano, L.J.2    Lory, S.3
  • 15
    • 39149126712 scopus 로고    scopus 로고
    • Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
    • Beckonert, O., Keun, H. C., Ebbels, T. M., Bundy, J., Holmes, E., Lindon, J. C., and Nicholson, J. K. (2007) Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts. Nat. Protoc. 2, 2692-2703
    • (2007) Nat. Protoc. , vol.2 , pp. 2692-2703
    • Beckonert, O.1    Keun, H.C.2    Ebbels, T.M.3    Bundy, J.4    Holmes, E.5    Lindon, J.C.6    Nicholson, J.K.7
  • 19
    • 84865128266 scopus 로고    scopus 로고
    • A Bayesian model of NMR spectra for the deconvolution and quantification of metabolites in complex biological mixtures
    • Astle, W., De Iorio, M., Richardson, S., Stephens, D., and Ebbels, T. (2012) A Bayesian model of NMR spectra for the deconvolution and quantification of metabolites in complex biological mixtures. J. Am. Stat. Assoc. 107, 1259-1271
    • (2012) J. Am. Stat. Assoc. , vol.107 , pp. 1259-1271
    • Astle, W.1    De Iorio, M.2    Richardson, S.3    Stephens, D.4    Ebbels, T.5
  • 20
    • 84865144924 scopus 로고    scopus 로고
    • BATMAN. An R package for the automated quantification of metabolites from nuclear magnetic resonance spectra using a Bayesian model
    • Hao, J., Astle, W., De Iorio, M., and Ebbels, T. M. (2012) BATMAN. An R package for the automated quantification of metabolites from nuclear magnetic resonance spectra using a Bayesian model. Bioinformatics 28, 2088-2090
    • (2012) Bioinformatics , vol.28 , pp. 2088-2090
    • Hao, J.1    Astle, W.2    De Iorio, M.3    Ebbels, T.M.4
  • 21
    • 84877329752 scopus 로고    scopus 로고
    • Combining spectral ordering with peak fitting for 1D NMR quantitative metabolomics
    • 10.1021/ac400237w
    • Liebeke, M., Hao, J., Ebbels, T. M. D., and Bundy, J. G. (2013) Combining spectral ordering with peak fitting for 1D NMR quantitative metabolomics. Anal. Chem. 85, 10.1021/ac400237w
    • (2013) Anal. Chem. , vol.85
    • Liebeke, M.1    Hao, J.2    Ebbels, T.M.D.3    Bundy, J.G.4
  • 22
    • 0018178434 scopus 로고
    • A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples
    • Markwell, M. A., Haas, S. M., Bieber, L. L., and Tolbert, N. E. (1978) A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal. Biochem. 87, 206-210 (Pubitemid 9050428)
    • (1978) Analytical Biochemistry , vol.87 , Issue.1 , pp. 206-210
    • Markwell, M.A.K.1    Haas, S.M.2    Bieber, L.L.3    Tolbert, N.E.4
  • 23
    • 0043032929 scopus 로고    scopus 로고
    • Phenotype MicroArray analysis of Escherichia coli K-12 mutants with deletions of all two-component systems
    • DOI 10.1128/JB.185.16.4956-4972.2003
    • Zhou, L., Lei, X. H., Bochner, B. R., and Wanner, B. L. (2003) Phenotype microarray analysis of Escherichia coli K-12 mutants with deletions of all two-component systems. J. Bacteriol. 185, 4956-4972 (Pubitemid 36962304)
    • (2003) Journal of Bacteriology , vol.185 , Issue.16 , pp. 4956-4972
    • Zhou, L.1    Lei, X.-H.2    Bochner, B.R.3    Wanner, B.L.4
  • 25
    • 72449186517 scopus 로고    scopus 로고
    • FiehnLib. Mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography/mass spectrometry
    • Kind, T., Wohlgemuth, G., Lee do, Y., Lu, Y., Palazoglu, M., Shahbaz, S., and Fiehn, O. (2009) FiehnLib. Mass spectral and retention index libraries for metabolomics based on quadrupole and time-of-flight gas chromatography/mass spectrometry. Anal. Chem. 81, 10038-10048
    • (2009) Anal. Chem. , vol.81 , pp. 10038-10048
    • Kind, T.1    Wohlgemuth, G.2    Lee Do, Y.3    Lu, Y.4    Palazoglu, M.5    Shahbaz, S.6    Fiehn, O.7
  • 26
    • 79958273162 scopus 로고    scopus 로고
    • A software complement to AMDIS for processing GC-MS metabolomic data
    • Behrends, V., Tredwell, G. D., and Bundy, J. G. (2011) A software complement to AMDIS for processing GC-MS metabolomic data. Anal. Biochem. 415, 206-208
    • (2011) Anal. Biochem. , vol.415 , pp. 206-208
    • Behrends, V.1    Tredwell, G.D.2    Bundy, J.G.3
  • 27
    • 84873101916 scopus 로고    scopus 로고
    • Metabolic adaptations of Pseudomonas aeruginosa during cystic fibrosis chronic lung infections
    • Behrends, V., Ryall, B., Zlosnik, J. E., Speert, D. P., Bundy, J. G., and Williams, H. D. (2013) Metabolic adaptations of Pseudomonas aeruginosa during cystic fibrosis chronic lung infections. Environ. Microbiol. 15, 398-408
    • (2013) Environ. Microbiol. , vol.15 , pp. 398-408
    • Behrends, V.1    Ryall, B.2    Zlosnik, J.E.3    Speert, D.P.4    Bundy, J.G.5    Williams, H.D.6
  • 28
    • 0029865389 scopus 로고    scopus 로고
    • Random amplified polymorphic DNA typing of Pseudomonas aeruginosa isolates recovered from patients with cystic fibrosis
    • Mahenthiralingam, E., Campbell, M. E., Foster, J., Lam, J. S., and Speert, D. P. (1996) Random amplified polymorphic DNA typing of Pseudomonas aeruginosa isolates recovered from patients with cystic fibrosis. J. Clin. Microbiol. 34, 1129-1135 (Pubitemid 26126878)
    • (1996) Journal of Clinical Microbiology , vol.34 , Issue.5 , pp. 1129-1135
    • Mahenthiralingam, E.1    Campbell, M.E.2    Foster, J.3    Lam, J.S.4    Speert, D.P.5
  • 30
    • 33745700438 scopus 로고    scopus 로고
    • Targeted profiling. Quantitative analysis of 1H NMR metabolomics data
    • Weljie, A. M., Newton, J., Mercier, P., Carlson, E., and Slupsky, C. M. (2006) Targeted profiling. Quantitative analysis of 1H NMR metabolomics data. Anal. Chem. 78, 4430-4442
    • (2006) Anal. Chem. , vol.78 , pp. 4430-4442
    • Weljie, A.M.1    Newton, J.2    Mercier, P.3    Carlson, E.4    Slupsky, C.M.5
  • 31
    • 81255129709 scopus 로고    scopus 로고
    • Between-person comparison of metabolite fitting for NMR-based quantitative metabolomics
    • Tredwell, G. D., Behrends, V., Geier, F. M., Liebeke, M., and Bundy, J. G. (2011) Between-person comparison of metabolite fitting for NMR-based quantitative metabolomics. Anal. Chem. 83, 8683-8687
    • (2011) Anal. Chem. , vol.83 , pp. 8683-8687
    • Tredwell, G.D.1    Behrends, V.2    Geier, F.M.3    Liebeke, M.4    Bundy, J.G.5
  • 32
    • 33645881935 scopus 로고    scopus 로고
    • Regulation of bacterial virulence by two-component systems
    • Beier, D., and Gross, R. (2006) Regulation of bacterial virulence by two-component systems. Curr. Opin. Microbiol. 9, 143-152
    • (2006) Curr. Opin. Microbiol. , vol.9 , pp. 143-152
    • Beier, D.1    Gross, R.2
  • 33
    • 26444481955 scopus 로고    scopus 로고
    • Two-component signal transduction pathways regulating growth and cell cycle progression in a bacterium. A system-level analysis
    • Skerker, J. M., Prasol, M. S., Perchuk, B. S., Biondi, E. G., and Laub, M. T. (2005) Two-component signal transduction pathways regulating growth and cell cycle progression in a bacterium. A system-level analysis. PLoS Biol. 3, e334
    • (2005) PLoS Biol. , vol.3
    • Skerker, J.M.1    Prasol, M.S.2    Perchuk, B.S.3    Biondi, E.G.4    Laub, M.T.5
  • 34
    • 32244434929 scopus 로고    scopus 로고
    • Influence of the regulatory protein RsmA on cellular functions in Pseudomonas aeruginosa PAO1, as revealed by transcriptome analysis
    • DOI 10.1099/mic.0.28324-0
    • Burrowes, E., Baysse, C., Adams, C., and O'Gara, F. (2006) Influence of the regulatory protein RsmA on cellular functions in Pseudomonas aeruginosa PAO1, as revealed by transcriptome analysis. Microbiology 152, 405-418 (Pubitemid 43210672)
    • (2006) Microbiology , vol.152 , Issue.2 , pp. 405-418
    • Burrowes, E.1    Baysse, C.2    Adams, C.3    O'Gara, F.4
  • 35
    • 0037609040 scopus 로고    scopus 로고
    • Posttranscriptional control of quorum-sensing-dependent virulence genes by DksA in Pseudomonas aeruginosa
    • DOI 10.1128/JB.185.12.3558-3566.2003
    • Jude, F., Köhler, T., Branny, P., Perron, K., Mayer, M. P., Comte, R., and van Delden, C. (2003) Posttranscriptional control of quorum-sensing-dependent virulence genes by DksA in Pseudomonas aeruginosa. J. Bacteriol. 185, 3558-3566 (Pubitemid 36676422)
    • (2003) Journal of Bacteriology , vol.185 , Issue.12 , pp. 3558-3566
    • Jude, F.1    Kohler, T.2    Branny, P.3    Perron, K.4    Mayer, M.P.5    Comte, R.6    Van Delden, C.7
  • 36
    • 0034748355 scopus 로고    scopus 로고
    • The global posttranscriptional regulator RsmA modulates production of virulence determinants and N-acylhomoserine lactones in Pseudomonas aeruginosa
    • DOI 10.1128/JB.183.22.6676-6683.2001
    • Pessi, G., Williams, F., Hindle, Z., Heurlier, K., Holden, M. T., Cámara, M., Haas, D., and Williams, P. (2001) The global posttranscriptional regulator RsmA modulates production of virulence determinants and N-acylhomoserine lactones in Pseudomonas aeruginosa. J. Bacteriol. 183, 6676-6683 (Pubitemid 33026760)
    • (2001) Journal of Bacteriology , vol.183 , Issue.22 , pp. 6676-6683
    • Pessi, G.1    Williams, F.2    Hindle, Z.3    Heurlier, K.4    Holden, M.T.G.5    Camara, M.6    Haas, D.7    Williams, P.8
  • 37
    • 0035212033 scopus 로고    scopus 로고
    • Differential roles of the Pseudomonas aeruginosa PA14 rpoN gene in pathogenicity in plants, nematodes, insects, and mice
    • DOI 10.1128/JB.183.24.7126-7134.2001
    • Hendrickson, E. L., Plotnikova, J., Mahajan-Miklos, S., Rahme, L. G., and Ausubel, F. M. (2001) Differential roles of the Pseudomonas aeruginosa PA14 rpoN gene in pathogenicity in plants, nematodes, insects, and mice. J. Bacteriol. 183, 7126-7134 (Pubitemid 33121846)
    • (2001) Journal of Bacteriology , vol.183 , Issue.24 , pp. 7126-7134
    • Hendrickson, E.L.1    Plotnikova, J.2    Mahajan-Miklos, S.3    Rahme, L.G.4    Ausubel, F.M.5
  • 38
    • 33749255145 scopus 로고    scopus 로고
    • Oxygen, cyanide and energy generation in the cystic fibrosis pathogen Pseudomonas aeruginosa
    • Williams, H. D., Zlosnik, J. E., and Ryall, B. (2007) Oxygen, cyanide and energy generation in the cystic fibrosis pathogen Pseudomonas aeruginosa. Adv. Microb. Physiol. 52, 1-71
    • (2007) Adv. Microb. Physiol. , vol.52 , pp. 1-71
    • Williams, H.D.1    Zlosnik, J.E.2    Ryall, B.3
  • 39
    • 77955132055 scopus 로고    scopus 로고
    • Carbon catabolite repression in Pseudomonas. Optimizing metabolic versatility and interactions with the environment
    • Rojo, F. (2010) Carbon catabolite repression in Pseudomonas. Optimizing metabolic versatility and interactions with the environment. FEMS Microbiol. Rev. 34, 658-684
    • (2010) FEMS Microbiol. Rev. , vol.34 , pp. 658-684
    • Rojo, F.1
  • 40
    • 70350458106 scopus 로고    scopus 로고
    • Isocitrate lyase supplies precursors for hydrogen cyanide production in a cystic fibrosis isolate of Pseudomonas aeruginosa
    • Hagins, J. M., Locy, R., and Silo-Suh, L. (2009) Isocitrate lyase supplies precursors for hydrogen cyanide production in a cystic fibrosis isolate of Pseudomonas aeruginosa. J. Bacteriol. 191, 6335-6339
    • (2009) J. Bacteriol. , vol.191 , pp. 6335-6339
    • Hagins, J.M.1    Locy, R.2    Silo-Suh, L.3
  • 41
    • 77950675370 scopus 로고    scopus 로고
    • Influence of RpoN on isocitrate lyase activity in Pseudomonas aeruginosa
    • Hagins, J. M., Scoffield, J. A., Suh, S. J., and Silo-Suh, L. (2010) Influence of RpoN on isocitrate lyase activity in Pseudomonas aeruginosa. Microbiology 156, 1201-1210
    • (2010) Microbiology , vol.156 , pp. 1201-1210
    • Hagins, J.M.1    Scoffield, J.A.2    Suh, S.J.3    Silo-Suh, L.4
  • 42
    • 79952228717 scopus 로고    scopus 로고
    • Malate synthase expression is deregulated in the Pseudomonas aeruginosa cystic fibrosis isolate FRD1
    • Hagins, J. M., Scoffield, J., Suh, S. J., and Silo-Suh, L. (2011) Malate synthase expression is deregulated in the Pseudomonas aeruginosa cystic fibrosis isolate FRD1. Can J. Microbiol. 57, 186-195
    • (2011) Can J. Microbiol. , vol.57 , pp. 186-195
    • Hagins, J.M.1    Scoffield, J.2    Suh, S.J.3    Silo-Suh, L.4
  • 43
    • 48449102828 scopus 로고    scopus 로고
    • Virulence determinants from a cystic fibrosis isolate of Pseudomonas aeruginosa include isocitrate lyase
    • Lindsey, T. L., Hagins, J. M., Sokol, P. A., and Silo-Suh, L. A. (2008) Virulence determinants from a cystic fibrosis isolate of Pseudomonas aeruginosa include isocitrate lyase. Microbiology 154, 1616-1627
    • (2008) Microbiology , vol.154 , pp. 1616-1627
    • Lindsey, T.L.1    Hagins, J.M.2    Sokol, P.A.3    Silo-Suh, L.A.4
  • 44
    • 27744562615 scopus 로고    scopus 로고
    • Adaptations of Pseudomonas aeruginosa to the cystic fibrosis lung environment can include deregulation of zwf, encoding glucose-6-phosphate dehydrogenase
    • DOI 10.1128/JB.187.22.7561-7568.2005
    • Silo-Suh, L., Suh, S. J., Phibbs, P. V., and Ohman, D. E. (2005) Adaptations of Pseudomonas aeruginosa to the cystic fibrosis lung environment can include deregulation of zwf, encoding glucose-6-phosphate dehydrogenase. J. Bacteriol. 187, 7561-7568 (Pubitemid 41587694)
    • (2005) Journal of Bacteriology , vol.187 , Issue.22 , pp. 7561-7568
    • Silo-Suh, L.1    Suh, S.-J.2    Phibbs, P.V.3    Ohman, D.E.4
  • 50
    • 0347567138 scopus 로고    scopus 로고
    • The σ54 regulon (sigmulon) of Pseudomonas putida
    • Cases, I., Ussery, D. W., and de Lorenzo, V. (2003) The σ54 regulon (sigmulon) of Pseudomonas putida. Environ. Microbiol. 5, 1281-1293
    • (2003) Environ. Microbiol. , vol.5 , pp. 1281-1293
    • Cases, I.1    Ussery, D.W.2    De Lorenzo, V.3
  • 51
    • 0024720114 scopus 로고
    • Involvement of Pseudomonas putida RpoN σ factor in regulation of various metabolic functions
    • Köhler, T., Harayama, S., Ramos, J. L., and Timmis, K. N. (1989) Involvement of Pseudomonas putida RpoN σ factor in regulation of various metabolic functions. J. Bacteriol. 171, 4326-4333
    • (1989) J. Bacteriol. , vol.171 , pp. 4326-4333
    • Köhler, T.1    Harayama, S.2    Ramos, J.L.3    Timmis, K.N.4
  • 52
    • 34547614085 scopus 로고    scopus 로고
    • Regulation of carbon and nitrogen utilization by CbrAB and NtrBC two-component systems in Pseudomonas aeruginosa
    • DOI 10.1128/JB.00432-07
    • Li, W., and Lu, C. D. (2007) Regulation of carbon and nitrogen utilization by CbrAB and NtrBC two-component systems in Pseudomonas aeruginosa. J. Bacteriol. 189, 5413-5420 (Pubitemid 47206386)
    • (2007) Journal of Bacteriology , vol.189 , Issue.15 , pp. 5413-5420
    • Li, W.1    Lu, C.-D.2
  • 53
    • 0035018558 scopus 로고    scopus 로고
    • The CbrA-CbrB two-component regulatory system controls the utilization of multiple carbon and nitrogen sources in Pseudomonas aeruginosa
    • DOI 10.1046/j.1365-2958.2001.02435.x
    • Nishijyo, T., Haas, D., and Itoh, Y. (2001) The CbrA-CbrB two-component regulatory system controls the utilization of multiple carbon and nitrogen sources in Pseudomonas aeruginosa. Mol. Microbiol. 40, 917-931 (Pubitemid 32523189)
    • (2001) Molecular Microbiology , vol.40 , Issue.4 , pp. 917-931
    • Nishijyo, T.1    Haas, D.2    Itoh, Y.3
  • 54
    • 40849100635 scopus 로고    scopus 로고
    • Dual involvement of CbrAB and NtrBC in the regulation of histidine utilization in Pseudomonas fluorescens SBW25
    • Zhang, X. X., and Rainey, P. B. (2008) Dual involvement of CbrAB and NtrBC in the regulation of histidine utilization in Pseudomonas fluorescens SBW25. Genetics 178, 185-195
    • (2008) Genetics , vol.178 , pp. 185-195
    • Zhang, X.X.1    Rainey, P.B.2
  • 55
    • 84868107469 scopus 로고    scopus 로고
    • Novel targets of the CbrAB/Crc carbon catabolite control system revealed by transcript abundance in Pseudomonas aeruginosa
    • Sonnleitner, E., Valentini, M., Wenner, N., Haichar Fel, Z., Haas, D., and Lapouge, K. (2012) Novel targets of the CbrAB/Crc carbon catabolite control system revealed by transcript abundance in Pseudomonas aeruginosa. PLoS ONE 7, e44637
    • (2012) PLoS ONE , vol.7
    • Sonnleitner, E.1    Valentini, M.2    Wenner, N.3    Haichar Fel, Z.4    Haas, D.5    Lapouge, K.6
  • 56
    • 78649333094 scopus 로고    scopus 로고
    • Computational prediction of the Crc regulon identifies genus-wide and speciesspecific targets of catabolite repression control in Pseudomonas bacteria
    • Browne, P., Barret, M., O'Gara, F., and Morrissey, J. P. (2010) Computational prediction of the Crc regulon identifies genus-wide and speciesspecific targets of catabolite repression control in Pseudomonas bacteria. BMC Microbiol. 10, 300
    • (2010) BMC Microbiol. , vol.10 , pp. 300
    • Browne, P.1    Barret, M.2    O'Gara, F.3    Morrissey, J.P.4
  • 57
    • 64749088448 scopus 로고    scopus 로고
    • Time-resolved metabolic footprinting for non-linear modelling of bacterial substrate utilization
    • Behrends, V., Ebbels, T. M., Williams, H. D., and Bundy, J. G. (2009) Time-resolved metabolic footprinting for non-linear modelling of bacterial substrate utilization. Appl. Environ. Microbiol. 75, 2453-2463
    • (2009) Appl. Environ. Microbiol. , vol.75 , pp. 2453-2463
    • Behrends, V.1    Ebbels, T.M.2    Williams, H.D.3    Bundy, J.G.4
  • 58
    • 67649201763 scopus 로고    scopus 로고
    • The Pseudomonas putida Crc global regulator controls the hierarchical assimilation of amino acids in a complete medium: Evidence from proteomic and genomic analyses
    • Moreno, R., Martínez-Gomariz, M., Yuste, L., Gil, C., and Rojo, F. (2009) The Pseudomonas putida Crc global regulator controls the hierarchical assimilation of amino acids in a complete medium: evidence from proteomic and genomic analyses. Proteomics 9, 2910-2928
    • (2009) Proteomics , vol.9 , pp. 2910-2928
    • Moreno, R.1    Martínez-Gomariz, M.2    Yuste, L.3    Gil, C.4    Rojo, F.5
  • 59
    • 34247509259 scopus 로고    scopus 로고
    • The Pseudomonas putida Crc global regulator is an RNA binding protein that inhibits translation of the AlkS transcriptional regulator
    • DOI 10.1111/j.1365-2958.2007.05685.x
    • Moreno, R., Ruiz-Manzano, A., Yuste, L., and Rojo, F. (2007) The Pseudomonas putida Crc global regulator is an RNA binding protein that inhibits translation of the AlkS transcriptional regulator. Mol. Microbiol. 64, 665-675 (Pubitemid 46653208)
    • (2007) Molecular Microbiology , vol.64 , Issue.3 , pp. 665-675
    • Moreno, R.1    Ruiz-Manzano, A.2    Yuste, L.3    Rojo, F.4
  • 60
    • 76049120271 scopus 로고    scopus 로고
    • Small RNA as global regulator of carbon catabolite repression in Pseudomonas aeruginosa
    • Sonnleitner, E., Abdou, L., and Haas, D. (2009) Small RNA as global regulator of carbon catabolite repression in Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. U.S.A. 106, 21866-21871
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 21866-21871
    • Sonnleitner, E.1    Abdou, L.2    Haas, D.3
  • 61
    • 77249159843 scopus 로고    scopus 로고
    • Metabolic profiling of Pseudomonas aeruginosa demonstrates that the anti-sigma factor MucA modulates osmotic stress tolerance
    • Behrends, V., Ryall, B., Wang, X., Bundy, J. G., and Williams, H. D. (2010) Metabolic profiling of Pseudomonas aeruginosa demonstrates that the anti-sigma factor MucA modulates osmotic stress tolerance. Mol. Biosyst. 6, 562-569
    • (2010) Mol. Biosyst. , vol.6 , pp. 562-569
    • Behrends, V.1    Ryall, B.2    Wang, X.3    Bundy, J.G.4    Williams, H.D.5
  • 62
    • 38849136576 scopus 로고    scopus 로고
    • Investigation of the algT operon sequence in mucoid and non-mucoid Pseudomonas aeruginosa isolates from 115 Scandinavian patients with cystic fibrosis and in 88 in vitro non-mucoid revertants
    • DOI 10.1099/mic.0.2007/010421-0
    • Ciofu, O., Lee, B., Johannesson, M., Hermansen, N. O., Meyer, P., and Høiby, N. (2008) Investigation of the algT operon sequence in mucoid and non-mucoid Pseudomonas aeruginosa isolates from 115 Scandinavian patients with cystic fibrosis and in 88 in vitro non-mucoid revertants. Microbiology 154, 103-113 (Pubitemid 351201391)
    • (2008) Microbiology , vol.154 , Issue.1 , pp. 103-113
    • Ciofu, O.1    Lee, B.2    Johannesson, M.3    Hermansen, N.O.4    Meyer, P.5    Hoiby, N.6
  • 63
    • 79953262396 scopus 로고    scopus 로고
    • Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis
    • Høiby, N. (2011) Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. BMC Med. 9, 32
    • (2011) BMC Med. , vol.9 , pp. 32
    • Høiby, N.1
  • 65
    • 83655197509 scopus 로고    scopus 로고
    • Microbial environments confound antibiotic efficacy
    • Lee, H. H., and Collins, J. J. (2012) Microbial environments confound antibiotic efficacy. Nat. Chem. Biol. 8, 6-9
    • (2012) Nat. Chem. Biol. , vol.8 , pp. 6-9
    • Lee, H.H.1    Collins, J.J.2
  • 66
    • 84873430621 scopus 로고    scopus 로고
    • Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism
    • Derewacz, D. K., Goodwin, C. R., McNees, C. R., McLean, J. A., and Bachmann, B. O. (2013) Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism. Proc. Natl. Acad. Sci. U.S.A. 110, 2336-2341
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 2336-2341
    • Derewacz, D.K.1    Goodwin, C.R.2    McNees, C.R.3    McLean, J.A.4    Bachmann, B.O.5


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