Novel Targets of the CbrAB/Crc Carbon Catabolite Control System Revealed by Transcript Abundance in Pseudomonas aeruginosa

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Sonnleitner, Elisabeth ^a   Valentini, Martina ^b   Wenner, Nicolas ^b   Haichar, Feth el Zahar ^b,c   Haas, Dieter ^b   Lapouge, Karine ^b  

^a UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c University of Lyon   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CARBON; CATABOLITE REPRESSION CONTROL PROTEIN; CATABOLITE REPRESSION CONTROL Z PROTEIN; PROTEIN CBRA; PROTEIN CBRB; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ACSA GENE; AROP2 GENE; ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BKDR GENE; CARBON SOURCE; CARBON UTILIZATION; CATABOLITE REPRESSION; CYSTIC FIBROSIS; ESTA GENE; GENE TARGETING; GENETIC TRANSCRIPTION; ILVE GENE; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN MOTIF; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION;

CARBON; GENES, BACTERIAL; PSEUDOMONAS AERUGINOSA; RNA, MESSENGER;

PSEUDOMONAS AERUGINOSA;

EID: 84868107469     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0044637     Document Type: Article

References (45)

1. Sonnleitner E, Abdou L, Haas D, (2009) Small RNA as global regulator of carbon catabolite repression in Pseudomonas aeruginosa. Proc Natl Acad Sci USA 106: 21866-21871.
2. Moreno R, Marzi S, Romby P, Rojo F, (2009) The Crc global regulator binds to an unpaired A-rich motif at the Pseudomonas putida alkS mRNA coding sequence and inhibits translation initiation. Nucleic Acids Res 37: 7678-7690.
3. Rojo F, (2010) Carbon catabolite repression in Pseudomonas: optimizing metabolic versatility and interactions with the environment. FEMS Microbiol Rev 34: 658-684.
4. Sonnleitner E, Haas D, (2011) Small RNAs as regulators of primary and secondary metabolism in Pseudomonas species. Appl Microbiol Biotechnol 91: 63-79.
5. Abdou L, Chou H-T, Haas D, Lu C-D, (2011) Promoter recognition and activation by the global response regulator CbrB in Pseudomonas aeruginosa. J Bacteriol 193: 2784-2792.
6. Yeung AT, Bains M, Hancock RE, (2011) The sensor kinase CbrA is a global regulator that modulates metabolism, virulence, and antibiotic resistance in Pseudomonas aeruginosa. J Bacteriol 193: 918-931.
7. Linares JF, Moreno R, Fajardo A, Martínez L, Escalante R, et al. (2010) The global regulator Crc modulates metabolism, susceptibility to antibiotics and virulence in Pseudomonas aeruginosa. Environ Microbiol 12: 3196-3212.
8. Burrowes E, Baysse C, Adams C, O'Gara F, (2006) Influence of the regulatory protein RsmA on cellular functions in Pseudomonas aeruginosa PAO1, as revealed by transcriptome analysis. Microbiology 152: 405-418.
9. Brencic A, Lory S, (2009) Determination of the regulon and identification of novel mRNA targets of Pseudomonas aeruginosa RsmA. Mol Microbiol 72: 612-632.
10. Brencic A, McFarland KA, McManus HR, Castang S, Mogno I, et al. (2009) The GacS/GacA signal transduction system of Pseudomonas aeruginosa acts exclusively through its control over the transcription of the RsmY and RsmZ regulatory small RNAs. Mol Microbiol 73: 434-445.
11. Hassan KA, Johnson A, Shaffer BT, Ren Q, Kidarsa TA, et al. (2010) Inactivation of the GacA response regulator in Pseudomonas fluorescens Pf-5 has far-reaching transcriptomic consequences. Environ Microbiol 12: 899-915.
12. Sezonov G, Joseleau-Petit D, D'Ari R, (2007) Escherichia coli physiology in Luria-Bertani broth. J Bacteriol 189: 8746-8749.
13. Drew R, Haq M (2004) Lessons from the ami operon. In: Ramos J-L, editor. Pseudomonas: Virulence and gene regulation, volume 2. New York: Kluwer Academic/Plenum. 425-449.
14. Itoh Y, Nishijyo T, Nakada Y (2007) Histidine catabolism and catabolic regulation, In: Ramos J-L, Filloux A, editors. Pseudomonas- A model system in biology, volume 5. Dordrecht: Springer. 371-395.
15. Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, et al. (2011) Quinolones: from antibiotics to autoinducers. FEMS Microbiol Rev 35: 247-274.
16. Görisch H, (2003) The ethanol oxidation system and its regulation in Pseudomonas aeruginosa. Biochim Biophys Acta 1647: 98-102.
17. Gliese N, Khodaverdi V, Schobert M, Görisch H, (2004) AgmR controls transcription of a regulon with several operons essential for ethanol oxidation in Pseudomonas aeruginosa ATCC 17933. Microbiology 150: 1851-1857.
18. Huang J, Sonnleitner E, Ren B, Xu Y, Haas D, (2012) Catabolite repression control of pyocyanin biosynthesis at an intersection of primary and secondary metabolism in Pseudomonas aeruginosa. Appl Environ Microbiol 78: 5016-5020.
19. Wilhelm S, Rosenau F, Kolmar H, Jaeger KE, (2011) Autotransporters with GDSL passenger domains: molecular physiology and biotechnological applications. Chembiochem 12: 1476-1485.
20. Stuer W, Jaeger KE, Winkler UK, (1986) Purification of extracellular lipase from Pseudomonas aeruginosa. J Bacteriol 168: 1070-1074.
21. Wilhelm S, Tommassen J, Jaeger KE, (1999) A novel lipolytic enzyme located in the outer membrane of Pseudomonas aeruginosa. J Bacteriol 181: 6977-6986.
22. Kretzschmar U, Khodaverdi V, Adrian L, (2010) Transcriptional regulation of the acetyl-CoA synthetase gene acsA in Pseudomonas aeruginosa. Arch Microbiol 192: 685-690.
23. Nishijyo T, Haas D, Itoh Y, (2001) The CbrA-CbrB two-component regulatory system controls the utilization of multiple carbon and nitrogen sources in Pseudomonas aeruginosa. Mol Microbiol 40: 917-931.
24. Hester KL, Lehman J, Najar F, Song L, Roe BA, et al. (2000) Crc is involved in catabolite repression control of the bkd operons of Pseudomonas putida and Pseudomonas aeruginosa. J Bacteriol 182: 1144-1149.
25. Martin RR, Marshall VD, Sokatch JR, Unger L, (1973) Common enzymes of branched-chain amino acid catabolism in Pseudomonas putida. J Bacteriol 115: 198-204.
26. Moreno R, Martínez-Gomariz M, Yuste L, Gil C, Rojo F, (2009) The Pseudomonas putida Crc global regulator controls the hierarchical assimilation of amino acids in a complete medium: evidence from proteomic and genomic analyses. Proteomics 9: 2910-2928.
27. Madhusudhan KT, Lorenz D, Sokatch JR, (1993) The bkdR gene of Pseudomonas putida is required for expression of the bkd operon and encodes a protein related to Lrp of Escherichia coli. J Bacteriol 175: 3934-3940.
28. Hester KL, Madhusudhan KT, Sokatch JR, (2000) Catabolite repression control by crc in 2xYT medium is mediated by posttranscriptional regulation of bkdR expression in Pseudomonas putida. J Bacteriol 182: 1150-1153.
29. Palmer KL, Mashburn LM, Singh PK, Whiteley M, (2005) Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. J Bacteriol 187: 5267-5277.
30. Palmer KL, Aye LM, Whiteley M, (2007) Nutritional cues control Pseudomonas aeruginosa multicellular behavior in cystic fibrosis sputum. J Bacteriol 189: 8079-8087.
31. Palmer GC, Palmer KC, Jorth PA, Whiteley M, (2010) Characterization of the Pseudomonas aeruginosa transcriptional response to phenylalanine and tyrosine. J Bacteriol 192: 2722-2728.
32. de Kievit TR, (2009) Quorum sensing in Pseudomonas aeruginosa biofilms. Environ Microbiol 11: 279-288.
33. Kaberdin VR, Bläsi U, (2006) Translation initiation and the fate of bacterial mRNAs. FEMS Microbiol Rev 30: 967-979.
34. O'Toole GA, Gibbs KA, Hager PW, Phibbs PV Jr, Kolter R, (2000) The global carbon metabolism regulator Crc is a component of a signal transduction pathway required for biofilm development by Pseudomonas aeruginosa. J Bacteriol 182: 425-431.
35. Hoshino T, Kageyama M, (1980) Purification and properties of a binding protein for branched-chain amino acids in Pseudomonas aeruginosa. J Bacteriol 141: 1055-1063.
36. Hoshino T, Kose K, (1990) Cloning, nucleotide sequences, and identification of products of the Pseudomonas aeruginosa PAO bra genes, which encode the high-affinity branched-chain amino acid transport system. J Bacteriol 172: 5531-5539.
37. Costerton JW, Lewandowski Z, Caldwell DE, Korber DR, Lappin-Scott HM, (1995) Microbial biofilms. Annu Rev Microbiol 49: 711-745.
38. O'Toole GA, Kolter R, (1998) Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, convergent signalling pathways: a genetic analysis. Mol Microbiol 28: 449-461.
39. Amador CI, Canosa I, Govantes F, Santero E, (2010) Lack of CbrB in Pseudomonas putida affects not only amino acids metabolism but also different stress responses and biofilm development. Environ Microbiol 12: 1748-1761.
40. Miller JH (1972) Experiments in Molecular Genetics. Cold Spring Harbor: Cold Spring Harbor Laboratory Press.
41. Durham DR, Phibbs PV Jr, (1982) Fractionation and characterization of the phosphoenolpyruvate: fructose 1-phosphotransferase system from Pseudomonas aeruginosa. J Bacteriol 149: 534-541.
42. Sonnleitner E, Gonzalez N, Sorger-Domenigg T, Heeb S, Richter AS, et al. (2011) The small RNA PhrS stimulates synthesis of the Pseudomonas aeruginosa quinolone signal. Mol Microbiol 80: 868-885.
43. Caille O, Rossier C, Perron K, (2007) A copper-activated two-component system interacts with zinc and imipenem resistance in Pseudomonas aeruginosa. J Bacteriol 189: 4561-4568.
44. Merritt JH, Kadouri DE, O'Toole GA (2005) Growing and analyzing static biofilms. Current Protocols in Microbiology 1B.1.1-1B.1.17.
45. Winsor GL, Lam DK, Fleming L, Lo R, Whiteside MD, et al. (2011) Nucleic Acids Res. 39 (Database issue): D596-600.