-
1
-
-
79960119761
-
Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and up-regulating BH3-only protein Noxa
-
Albershardt T.C., Salerni B.L., Soderquist R.S., Bates D.J., Pletnev A.A., Kisselev A.F., Eastman A. Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and up-regulating BH3-only protein Noxa. J. Biol. Chem. 2011, 286:24882-24895.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 24882-24895
-
-
Albershardt, T.C.1
Salerni, B.L.2
Soderquist, R.S.3
Bates, D.J.4
Pletnev, A.A.5
Kisselev, A.F.6
Eastman, A.7
-
2
-
-
33745006592
-
The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells
-
Alves N.L., Derks I.A., Berk E., Spijker R., van Lier R.A., Eldering E. The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells. Immunity 2006, 24:703-716.
-
(2006)
Immunity
, vol.24
, pp. 703-716
-
-
Alves, N.L.1
Derks, I.A.2
Berk, E.3
Spijker, R.4
van Lier, R.A.5
Eldering, E.6
-
3
-
-
84861633336
-
Mcl-1 rescues a glitch in the matrix
-
Andersen J.L., Kornbluth S. Mcl-1 rescues a glitch in the matrix. Nat. Cell. Biol. 2012, 14:563-565.
-
(2012)
Nat. Cell. Biol.
, vol.14
, pp. 563-565
-
-
Andersen, J.L.1
Kornbluth, S.2
-
4
-
-
0037366067
-
Neuroblastoma: biological insights into a clinical enigma
-
Brodeur G.M. Neuroblastoma: biological insights into a clinical enigma. Nat. Rev. Cancer 2003, 3:203-216.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 203-216
-
-
Brodeur, G.M.1
-
5
-
-
84862928682
-
Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity in vivo
-
Budhraja A., Gao N., Zhang Z., Son Y.O., Cheng S., Wang X., Ding S., Hitron A., Chen G., Luo J., Shi X. Apigenin induces apoptosis in human leukemia cells and exhibits anti-leukemic activity in vivo. Mol. Cancer Ther. 2012, 11:132-142.
-
(2012)
Mol. Cancer Ther.
, vol.11
, pp. 132-142
-
-
Budhraja, A.1
Gao, N.2
Zhang, Z.3
Son, Y.O.4
Cheng, S.5
Wang, X.6
Ding, S.7
Hitron, A.8
Chen, G.9
Luo, J.10
Shi, X.11
-
6
-
-
84860797409
-
Apigenin induces apoptosis via tumor necrosis factor receptor- and Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin
-
Chan L.P., Chou T.H., Ding H.Y., Chen P.R., Chiang F.Y., Kuo P.L., Liang C.H. Apigenin induces apoptosis via tumor necrosis factor receptor- and Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin. Biochim. Biophys. Acta 2012, 1820:1081-1091.
-
(2012)
Biochim. Biophys. Acta
, vol.1820
, pp. 1081-1091
-
-
Chan, L.P.1
Chou, T.H.2
Ding, H.Y.3
Chen, P.R.4
Chiang, F.Y.5
Kuo, P.L.6
Liang, C.H.7
-
7
-
-
0035839554
-
Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle
-
Chen X., Johns D.C., Geiman D.E., Marban E., Dang D.T., Hamlin G., Sun R., Yang V.W. Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle. J. Biol. Chem. 2001, 276:30423-30428.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30423-30428
-
-
Chen, X.1
Johns, D.C.2
Geiman, D.E.3
Marban, E.4
Dang, D.T.5
Hamlin, G.6
Sun, R.7
Yang, V.W.8
-
8
-
-
33748794547
-
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
-
Chou T.C. Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol. Rev. 2006, 58:621-681.
-
(2006)
Pharmacol. Rev.
, vol.58
, pp. 621-681
-
-
Chou, T.C.1
-
9
-
-
45849104776
-
Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1
-
Day C.L., Smits C., Fan F.C., Lee E.F., Fairlie W.D., Hinds M.G. Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1. J. Mol. Biol. 2008, 380:958-971.
-
(2008)
J. Mol. Biol.
, vol.380
, pp. 958-971
-
-
Day, C.L.1
Smits, C.2
Fan, F.C.3
Lee, E.F.4
Fairlie, W.D.5
Hinds, M.G.6
-
10
-
-
0030741461
-
Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis
-
Fotsis T., Pepper M.S., Aktas E., Breit S., Rasku S., Adlercreutz H., Wahala K., Montesano R., Schweigerer L. Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis. Cancer Res. 1997, 57:2916-2921.
-
(1997)
Cancer Res.
, vol.57
, pp. 2916-2921
-
-
Fotsis, T.1
Pepper, M.S.2
Aktas, E.3
Breit, S.4
Rasku, S.5
Adlercreutz, H.6
Wahala, K.7
Montesano, R.8
Schweigerer, L.9
-
11
-
-
0030798679
-
Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5
-
Gianelli G., Falk-Marziller J., Schiraldi O., Stetler-Stevenson W.G., Quaranta V. Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5. Science 1997, 277:225-228.
-
(1997)
Science
, vol.277
, pp. 225-228
-
-
Gianelli, G.1
Falk-Marziller, J.2
Schiraldi, O.3
Stetler-Stevenson, W.G.4
Quaranta, V.5
-
12
-
-
78650437352
-
Regulation of matrix metalloproteinase activity in health and disease
-
Hadler-Olsen E., Fadnes B., Sylte I., Uhlin-Hansen L., Winberg J.O. Regulation of matrix metalloproteinase activity in health and disease. FEBS J. 2011, 278:28-45.
-
(2011)
FEBS J.
, vol.278
, pp. 28-45
-
-
Hadler-Olsen, E.1
Fadnes, B.2
Sylte, I.3
Uhlin-Hansen, L.4
Winberg, J.O.5
-
13
-
-
70349441108
-
Putative tumor-suppressive function of Krüppel-like factor 4 in primary lung carcinoma
-
Hu W., Hofstetter W.L., Li H., Zhou Y., He Y., Pataer A., Wang L., Xie K., Swisher S.G., Fang B. Putative tumor-suppressive function of Krüppel-like factor 4 in primary lung carcinoma. Clin. Cancer Res. 2009, 15:5688-5695.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 5688-5695
-
-
Hu, W.1
Hofstetter, W.L.2
Li, H.3
Zhou, Y.4
He, Y.5
Pataer, A.6
Wang, L.7
Xie, K.8
Swisher, S.G.9
Fang, B.10
-
14
-
-
69949156043
-
Bcl-2 inhibitor and apigenin worked synergistically in human malignant neuroblastoma cell lines and increased apoptosis with activation of extrinsic and intrinsic pathways
-
Karmakar S., Davis K.A., Choudhury S.R., Deeconda A., Banik N.L., Ray S.K. Bcl-2 inhibitor and apigenin worked synergistically in human malignant neuroblastoma cell lines and increased apoptosis with activation of extrinsic and intrinsic pathways. Biochem. Biophys. Res. Commun. 2009, 388:705-710.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.388
, pp. 705-710
-
-
Karmakar, S.1
Davis, K.A.2
Choudhury, S.R.3
Deeconda, A.4
Banik, N.L.5
Ray, S.K.6
-
15
-
-
78149470355
-
KLF4 promotes hydrogen-peroxide-induced apoptosis of chronic myeloid leukemia cells involving the Bcl-2/Bax pathway
-
Li Z., Zhao J., Li Q., Yang W., Song Q., Li W., Liu J. KLF4 promotes hydrogen-peroxide-induced apoptosis of chronic myeloid leukemia cells involving the Bcl-2/Bax pathway. Cell Stress Chaperones 2010, 15:905-912.
-
(2010)
Cell Stress Chaperones
, vol.15
, pp. 905-912
-
-
Li, Z.1
Zhao, J.2
Li, Q.3
Yang, W.4
Song, Q.5
Li, W.6
Liu, J.7
-
16
-
-
34250683435
-
Neuroblastoma
-
Maris J.M., Hogarty M.D., Bagatell R., Cohn S.L. Neuroblastoma. Lancet 2007, 369:2106-2120.
-
(2007)
Lancet
, vol.369
, pp. 2106-2120
-
-
Maris, J.M.1
Hogarty, M.D.2
Bagatell, R.3
Cohn, S.L.4
-
17
-
-
77953523121
-
Recent advances in neuroblastoma
-
Maris J.M. Recent advances in neuroblastoma. N. Engl. J. Med. 2010, 362:2202-2211.
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 2202-2211
-
-
Maris, J.M.1
-
18
-
-
84861152766
-
Promising therapeutic targets in neuroblastoma
-
Matthay K.K., George R.E., Yu A.L. Promising therapeutic targets in neuroblastoma. Clin. Cancer Res. 2012, 18:2740-2753.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 2740-2753
-
-
Matthay, K.K.1
George, R.E.2
Yu, A.L.3
-
19
-
-
27944457637
-
Puma/Mcl-1 interaction is not sufficient to prevent rapid degradation of Mcl-1
-
Mei Y., Du W., Yang Y., Wu M. Puma/Mcl-1 interaction is not sufficient to prevent rapid degradation of Mcl-1. Oncogene 2005, 24:7224-7237.
-
(2005)
Oncogene
, vol.24
, pp. 7224-7237
-
-
Mei, Y.1
Du, W.2
Yang, Y.3
Wu, M.4
-
20
-
-
35448964624
-
Noxa/Mcl-1 balance regulates susceptibility of cells to camptothecin-induced apoptosis
-
Mei Y., Xie C., Xie W., Tian X., Li M., Wu M. Noxa/Mcl-1 balance regulates susceptibility of cells to camptothecin-induced apoptosis. Neoplasia 2007, 9:871-881.
-
(2007)
Neoplasia
, vol.9
, pp. 871-881
-
-
Mei, Y.1
Xie, C.2
Xie, W.3
Tian, X.4
Li, M.5
Wu, M.6
-
21
-
-
67651100626
-
Bcl-2 inhibitor HA14-1 and genistein together adeptly down regulated survival factors and activated cysteine proteases for apoptosis in human malignant neuroblastoma SK-N-BE2 and SH-SY5Y cells
-
Mohan N., Karmakar S., Choudhury S.R., Banik N.L., Ray S.K. Bcl-2 inhibitor HA14-1 and genistein together adeptly down regulated survival factors and activated cysteine proteases for apoptosis in human malignant neuroblastoma SK-N-BE2 and SH-SY5Y cells. Brain Res. 2009, 1283:155-166.
-
(2009)
Brain Res.
, vol.1283
, pp. 155-166
-
-
Mohan, N.1
Karmakar, S.2
Choudhury, S.R.3
Banik, N.L.4
Ray, S.K.5
-
22
-
-
81155160993
-
Combination of N-(4-hydroxyphenyl) retinamide and apigenin suppressed starvation-induced autophagy and promoted apoptosis in malignant neuroblastoma cells
-
Mohan N., Banik N.L., Ray S.K. Combination of N-(4-hydroxyphenyl) retinamide and apigenin suppressed starvation-induced autophagy and promoted apoptosis in malignant neuroblastoma cells. Neurosci. Lett. 2011, 502:24-29.
-
(2011)
Neurosci. Lett.
, vol.502
, pp. 24-29
-
-
Mohan, N.1
Banik, N.L.2
Ray, S.K.3
-
23
-
-
80655140637
-
L bountiful neuroblastoma cells by increasing differentiation and apoptosis
-
L bountiful neuroblastoma cells by increasing differentiation and apoptosis. Cancer Biol. Ther. 2011, 12:846-854.
-
(2011)
Cancer Biol. Ther.
, vol.12
, pp. 846-854
-
-
Mohan, N.1
Banik, N.L.2
Ray, S.K.3
-
24
-
-
79961207043
-
SU5416 and EGCG work synergistically and inhibit angiogenic and survival factors and induce cell cycle arrest to promote apoptosis in human malignant neuroblastoma SH-SY5Y and SK-N-BE2 cells
-
Mohan N., Karmakar S., Banik N.L., Ray S.K. SU5416 and EGCG work synergistically and inhibit angiogenic and survival factors and induce cell cycle arrest to promote apoptosis in human malignant neuroblastoma SH-SY5Y and SK-N-BE2 cells. Neurochem. Res. 2011, 36:1383-1396.
-
(2011)
Neurochem. Res.
, vol.36
, pp. 1383-1396
-
-
Mohan, N.1
Karmakar, S.2
Banik, N.L.3
Ray, S.K.4
-
25
-
-
34248226610
-
Apigenin and cancer chemoprevention: progress, potential and promise
-
Patel D., Shukla S., Gupta S. Apigenin and cancer chemoprevention: progress, potential and promise. Int. J. Oncol. 2007, 30:233-245.
-
(2007)
Int. J. Oncol.
, vol.30
, pp. 233-245
-
-
Patel, D.1
Shukla, S.2
Gupta, S.3
-
26
-
-
30144440248
-
The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene
-
Rowland B.D., Bernard R., Peepe D.S. The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene. Nat. Cell. Biol. 2005, 7:1074-1082.
-
(2005)
Nat. Cell. Biol.
, vol.7
, pp. 1074-1082
-
-
Rowland, B.D.1
Bernard, R.2
Peepe, D.S.3
-
27
-
-
0029829236
-
Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest
-
Shields J.M., Christy R.J., Yang V.W. Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest. J. Biol. Chem. 1996, 271:20009-20017.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20009-20017
-
-
Shields, J.M.1
Christy, R.J.2
Yang, V.W.3
-
28
-
-
59149098234
-
Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9
-
Song H., Li Y., Lee J., Schwartz A.L., Bu G. Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9. Cancer Res. 2009, 69:879-886.
-
(2009)
Cancer Res.
, vol.69
, pp. 879-886
-
-
Song, H.1
Li, Y.2
Lee, J.3
Schwartz, A.L.4
Bu, G.5
-
29
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
30
-
-
33745271531
-
Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migration
-
Wang L., Zhang Z.G., Zhang R.L., Gregg S.R., Hozeska-Solgot A., LeTourneau Y., Wang Y., Chopp M. Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migration. J. Neurosci. 2006, 26:5996-6003.
-
(2006)
J. Neurosci.
, vol.26
, pp. 5996-6003
-
-
Wang, L.1
Zhang, Z.G.2
Zhang, R.L.3
Gregg, S.R.4
Hozeska-Solgot, A.5
LeTourneau, Y.6
Wang, Y.7
Chopp, M.8
-
31
-
-
78650318077
-
Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration
-
Wang J., Place R.F., Huang V., Wang X., Noonan E.J., Magyar C.E., Huang J., Li L.C. Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration. Cancer Res. 2010, 70:10182-10191.
-
(2010)
Cancer Res.
, vol.70
, pp. 10182-10191
-
-
Wang, J.1
Place, R.F.2
Huang, V.3
Wang, X.4
Noonan, E.J.5
Magyar, C.E.6
Huang, J.7
Li, L.C.8
-
32
-
-
16844386207
-
Drastic down-regulation of Krüppel-like factor 4 expression is critical in human gastric cancer development and progression
-
Wei D., Gong W., Kanai M., Schlunk C., Wang L., Yao J.C., Wu T.T., Huang S., Xie K. Drastic down-regulation of Krüppel-like factor 4 expression is critical in human gastric cancer development and progression. Cancer Res. 2005, 65:2746-2754.
-
(2005)
Cancer Res.
, vol.65
, pp. 2746-2754
-
-
Wei, D.1
Gong, W.2
Kanai, M.3
Schlunk, C.4
Wang, L.5
Yao, J.C.6
Wu, T.T.7
Huang, S.8
Xie, K.9
-
33
-
-
83755163788
-
Synergistic effects of apigenin and paclitaxel on apoptosis of cancer cells
-
Xu Y., Xin Y., Diao Y., Lu C., Fu J., Luo L., Yin Z. Synergistic effects of apigenin and paclitaxel on apoptosis of cancer cells. PLoS One 2011, 6:29169.
-
(2011)
PLoS One
, vol.6
, pp. 29169
-
-
Xu, Y.1
Xin, Y.2
Diao, Y.3
Lu, C.4
Fu, J.5
Luo, L.6
Yin, Z.7
-
34
-
-
0037462796
-
Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage
-
Yoon H.S., Chen X., Yang V.W. Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage. J. Biol. Chem. 2003, 278:2101-2105.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2101-2105
-
-
Yoon, H.S.1
Chen, X.2
Yang, V.W.3
-
35
-
-
79960065994
-
Krüppel-like factor 4 inhibits tumorigenic progression and metastasis in a mouse model of breast cancer
-
Yori J.L., Seachrist D.D., Johnson E., Lozada K.L., Abdul-Karim F.W., Chodosh L.A., Schiemann W.P., Keri R.A. Krüppel-like factor 4 inhibits tumorigenic progression and metastasis in a mouse model of breast cancer. Neoplasia 2011, 13:601-610.
-
(2011)
Neoplasia
, vol.13
, pp. 601-610
-
-
Yori, J.L.1
Seachrist, D.D.2
Johnson, E.3
Lozada, K.L.4
Abdul-Karim, F.W.5
Chodosh, L.A.6
Schiemann, W.P.7
Keri, R.A.8
-
36
-
-
79955608022
-
Krüppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion
-
Yu F., Li J., Chen H., Fu J., Ray S., Huang S., Zheng H., Ai W. Krüppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion. Oncogene 2011, 30:2161-2172.
-
(2011)
Oncogene
, vol.30
, pp. 2161-2172
-
-
Yu, F.1
Li, J.2
Chen, H.3
Fu, J.4
Ray, S.5
Huang, S.6
Zheng, H.7
Ai, W.8
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