메뉴 건너뛰기




Volumn 7, Issue 3, 2013, Pages 464-474

KLF4 overexpression and apigenin treatment down regulated anti-apoptotic Bcl-2 proteins and matrix metalloproteinases to control growth of human malignant neuroblastoma SK-N-DZ and IMR-32 cells

Author keywords

Apigenin; Apoptosis; Combination therapy; KLF4; Neuroblastoma

Indexed keywords

APIGENIN; CASPASE 3; CASPASE ACTIVATED DEOXYRIBONUCLEASE; GELATINASE A; KRUPPEL LIKE FACTOR 4; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN P53;

EID: 84878116048     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2012.12.002     Document Type: Article
Times cited : (33)

References (36)
  • 1
    • 79960119761 scopus 로고    scopus 로고
    • Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and up-regulating BH3-only protein Noxa
    • Albershardt T.C., Salerni B.L., Soderquist R.S., Bates D.J., Pletnev A.A., Kisselev A.F., Eastman A. Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and up-regulating BH3-only protein Noxa. J. Biol. Chem. 2011, 286:24882-24895.
    • (2011) J. Biol. Chem. , vol.286 , pp. 24882-24895
    • Albershardt, T.C.1    Salerni, B.L.2    Soderquist, R.S.3    Bates, D.J.4    Pletnev, A.A.5    Kisselev, A.F.6    Eastman, A.7
  • 2
    • 33745006592 scopus 로고    scopus 로고
    • The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells
    • Alves N.L., Derks I.A., Berk E., Spijker R., van Lier R.A., Eldering E. The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells. Immunity 2006, 24:703-716.
    • (2006) Immunity , vol.24 , pp. 703-716
    • Alves, N.L.1    Derks, I.A.2    Berk, E.3    Spijker, R.4    van Lier, R.A.5    Eldering, E.6
  • 3
    • 84861633336 scopus 로고    scopus 로고
    • Mcl-1 rescues a glitch in the matrix
    • Andersen J.L., Kornbluth S. Mcl-1 rescues a glitch in the matrix. Nat. Cell. Biol. 2012, 14:563-565.
    • (2012) Nat. Cell. Biol. , vol.14 , pp. 563-565
    • Andersen, J.L.1    Kornbluth, S.2
  • 4
    • 0037366067 scopus 로고    scopus 로고
    • Neuroblastoma: biological insights into a clinical enigma
    • Brodeur G.M. Neuroblastoma: biological insights into a clinical enigma. Nat. Rev. Cancer 2003, 3:203-216.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 203-216
    • Brodeur, G.M.1
  • 6
    • 84860797409 scopus 로고    scopus 로고
    • Apigenin induces apoptosis via tumor necrosis factor receptor- and Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin
    • Chan L.P., Chou T.H., Ding H.Y., Chen P.R., Chiang F.Y., Kuo P.L., Liang C.H. Apigenin induces apoptosis via tumor necrosis factor receptor- and Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin. Biochim. Biophys. Acta 2012, 1820:1081-1091.
    • (2012) Biochim. Biophys. Acta , vol.1820 , pp. 1081-1091
    • Chan, L.P.1    Chou, T.H.2    Ding, H.Y.3    Chen, P.R.4    Chiang, F.Y.5    Kuo, P.L.6    Liang, C.H.7
  • 7
    • 0035839554 scopus 로고    scopus 로고
    • Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle
    • Chen X., Johns D.C., Geiman D.E., Marban E., Dang D.T., Hamlin G., Sun R., Yang V.W. Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle. J. Biol. Chem. 2001, 276:30423-30428.
    • (2001) J. Biol. Chem. , vol.276 , pp. 30423-30428
    • Chen, X.1    Johns, D.C.2    Geiman, D.E.3    Marban, E.4    Dang, D.T.5    Hamlin, G.6    Sun, R.7    Yang, V.W.8
  • 8
    • 33748794547 scopus 로고    scopus 로고
    • Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
    • Chou T.C. Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol. Rev. 2006, 58:621-681.
    • (2006) Pharmacol. Rev. , vol.58 , pp. 621-681
    • Chou, T.C.1
  • 9
    • 45849104776 scopus 로고    scopus 로고
    • Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1
    • Day C.L., Smits C., Fan F.C., Lee E.F., Fairlie W.D., Hinds M.G. Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1. J. Mol. Biol. 2008, 380:958-971.
    • (2008) J. Mol. Biol. , vol.380 , pp. 958-971
    • Day, C.L.1    Smits, C.2    Fan, F.C.3    Lee, E.F.4    Fairlie, W.D.5    Hinds, M.G.6
  • 14
    • 69949156043 scopus 로고    scopus 로고
    • Bcl-2 inhibitor and apigenin worked synergistically in human malignant neuroblastoma cell lines and increased apoptosis with activation of extrinsic and intrinsic pathways
    • Karmakar S., Davis K.A., Choudhury S.R., Deeconda A., Banik N.L., Ray S.K. Bcl-2 inhibitor and apigenin worked synergistically in human malignant neuroblastoma cell lines and increased apoptosis with activation of extrinsic and intrinsic pathways. Biochem. Biophys. Res. Commun. 2009, 388:705-710.
    • (2009) Biochem. Biophys. Res. Commun. , vol.388 , pp. 705-710
    • Karmakar, S.1    Davis, K.A.2    Choudhury, S.R.3    Deeconda, A.4    Banik, N.L.5    Ray, S.K.6
  • 15
    • 78149470355 scopus 로고    scopus 로고
    • KLF4 promotes hydrogen-peroxide-induced apoptosis of chronic myeloid leukemia cells involving the Bcl-2/Bax pathway
    • Li Z., Zhao J., Li Q., Yang W., Song Q., Li W., Liu J. KLF4 promotes hydrogen-peroxide-induced apoptosis of chronic myeloid leukemia cells involving the Bcl-2/Bax pathway. Cell Stress Chaperones 2010, 15:905-912.
    • (2010) Cell Stress Chaperones , vol.15 , pp. 905-912
    • Li, Z.1    Zhao, J.2    Li, Q.3    Yang, W.4    Song, Q.5    Li, W.6    Liu, J.7
  • 17
    • 77953523121 scopus 로고    scopus 로고
    • Recent advances in neuroblastoma
    • Maris J.M. Recent advances in neuroblastoma. N. Engl. J. Med. 2010, 362:2202-2211.
    • (2010) N. Engl. J. Med. , vol.362 , pp. 2202-2211
    • Maris, J.M.1
  • 18
    • 84861152766 scopus 로고    scopus 로고
    • Promising therapeutic targets in neuroblastoma
    • Matthay K.K., George R.E., Yu A.L. Promising therapeutic targets in neuroblastoma. Clin. Cancer Res. 2012, 18:2740-2753.
    • (2012) Clin. Cancer Res. , vol.18 , pp. 2740-2753
    • Matthay, K.K.1    George, R.E.2    Yu, A.L.3
  • 19
    • 27944457637 scopus 로고    scopus 로고
    • Puma/Mcl-1 interaction is not sufficient to prevent rapid degradation of Mcl-1
    • Mei Y., Du W., Yang Y., Wu M. Puma/Mcl-1 interaction is not sufficient to prevent rapid degradation of Mcl-1. Oncogene 2005, 24:7224-7237.
    • (2005) Oncogene , vol.24 , pp. 7224-7237
    • Mei, Y.1    Du, W.2    Yang, Y.3    Wu, M.4
  • 20
    • 35448964624 scopus 로고    scopus 로고
    • Noxa/Mcl-1 balance regulates susceptibility of cells to camptothecin-induced apoptosis
    • Mei Y., Xie C., Xie W., Tian X., Li M., Wu M. Noxa/Mcl-1 balance regulates susceptibility of cells to camptothecin-induced apoptosis. Neoplasia 2007, 9:871-881.
    • (2007) Neoplasia , vol.9 , pp. 871-881
    • Mei, Y.1    Xie, C.2    Xie, W.3    Tian, X.4    Li, M.5    Wu, M.6
  • 21
    • 67651100626 scopus 로고    scopus 로고
    • Bcl-2 inhibitor HA14-1 and genistein together adeptly down regulated survival factors and activated cysteine proteases for apoptosis in human malignant neuroblastoma SK-N-BE2 and SH-SY5Y cells
    • Mohan N., Karmakar S., Choudhury S.R., Banik N.L., Ray S.K. Bcl-2 inhibitor HA14-1 and genistein together adeptly down regulated survival factors and activated cysteine proteases for apoptosis in human malignant neuroblastoma SK-N-BE2 and SH-SY5Y cells. Brain Res. 2009, 1283:155-166.
    • (2009) Brain Res. , vol.1283 , pp. 155-166
    • Mohan, N.1    Karmakar, S.2    Choudhury, S.R.3    Banik, N.L.4    Ray, S.K.5
  • 22
    • 81155160993 scopus 로고    scopus 로고
    • Combination of N-(4-hydroxyphenyl) retinamide and apigenin suppressed starvation-induced autophagy and promoted apoptosis in malignant neuroblastoma cells
    • Mohan N., Banik N.L., Ray S.K. Combination of N-(4-hydroxyphenyl) retinamide and apigenin suppressed starvation-induced autophagy and promoted apoptosis in malignant neuroblastoma cells. Neurosci. Lett. 2011, 502:24-29.
    • (2011) Neurosci. Lett. , vol.502 , pp. 24-29
    • Mohan, N.1    Banik, N.L.2    Ray, S.K.3
  • 23
    • 80655140637 scopus 로고    scopus 로고
    • L bountiful neuroblastoma cells by increasing differentiation and apoptosis
    • L bountiful neuroblastoma cells by increasing differentiation and apoptosis. Cancer Biol. Ther. 2011, 12:846-854.
    • (2011) Cancer Biol. Ther. , vol.12 , pp. 846-854
    • Mohan, N.1    Banik, N.L.2    Ray, S.K.3
  • 24
    • 79961207043 scopus 로고    scopus 로고
    • SU5416 and EGCG work synergistically and inhibit angiogenic and survival factors and induce cell cycle arrest to promote apoptosis in human malignant neuroblastoma SH-SY5Y and SK-N-BE2 cells
    • Mohan N., Karmakar S., Banik N.L., Ray S.K. SU5416 and EGCG work synergistically and inhibit angiogenic and survival factors and induce cell cycle arrest to promote apoptosis in human malignant neuroblastoma SH-SY5Y and SK-N-BE2 cells. Neurochem. Res. 2011, 36:1383-1396.
    • (2011) Neurochem. Res. , vol.36 , pp. 1383-1396
    • Mohan, N.1    Karmakar, S.2    Banik, N.L.3    Ray, S.K.4
  • 25
    • 34248226610 scopus 로고    scopus 로고
    • Apigenin and cancer chemoprevention: progress, potential and promise
    • Patel D., Shukla S., Gupta S. Apigenin and cancer chemoprevention: progress, potential and promise. Int. J. Oncol. 2007, 30:233-245.
    • (2007) Int. J. Oncol. , vol.30 , pp. 233-245
    • Patel, D.1    Shukla, S.2    Gupta, S.3
  • 26
    • 30144440248 scopus 로고    scopus 로고
    • The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene
    • Rowland B.D., Bernard R., Peepe D.S. The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene. Nat. Cell. Biol. 2005, 7:1074-1082.
    • (2005) Nat. Cell. Biol. , vol.7 , pp. 1074-1082
    • Rowland, B.D.1    Bernard, R.2    Peepe, D.S.3
  • 27
    • 0029829236 scopus 로고    scopus 로고
    • Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest
    • Shields J.M., Christy R.J., Yang V.W. Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest. J. Biol. Chem. 1996, 271:20009-20017.
    • (1996) J. Biol. Chem. , vol.271 , pp. 20009-20017
    • Shields, J.M.1    Christy, R.J.2    Yang, V.W.3
  • 28
    • 59149098234 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9
    • Song H., Li Y., Lee J., Schwartz A.L., Bu G. Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9. Cancer Res. 2009, 69:879-886.
    • (2009) Cancer Res. , vol.69 , pp. 879-886
    • Song, H.1    Li, Y.2    Lee, J.3    Schwartz, A.L.4    Bu, G.5
  • 29
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 30
    • 33745271531 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migration
    • Wang L., Zhang Z.G., Zhang R.L., Gregg S.R., Hozeska-Solgot A., LeTourneau Y., Wang Y., Chopp M. Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migration. J. Neurosci. 2006, 26:5996-6003.
    • (2006) J. Neurosci. , vol.26 , pp. 5996-6003
    • Wang, L.1    Zhang, Z.G.2    Zhang, R.L.3    Gregg, S.R.4    Hozeska-Solgot, A.5    LeTourneau, Y.6    Wang, Y.7    Chopp, M.8
  • 31
    • 78650318077 scopus 로고    scopus 로고
    • Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration
    • Wang J., Place R.F., Huang V., Wang X., Noonan E.J., Magyar C.E., Huang J., Li L.C. Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration. Cancer Res. 2010, 70:10182-10191.
    • (2010) Cancer Res. , vol.70 , pp. 10182-10191
    • Wang, J.1    Place, R.F.2    Huang, V.3    Wang, X.4    Noonan, E.J.5    Magyar, C.E.6    Huang, J.7    Li, L.C.8
  • 32
    • 16844386207 scopus 로고    scopus 로고
    • Drastic down-regulation of Krüppel-like factor 4 expression is critical in human gastric cancer development and progression
    • Wei D., Gong W., Kanai M., Schlunk C., Wang L., Yao J.C., Wu T.T., Huang S., Xie K. Drastic down-regulation of Krüppel-like factor 4 expression is critical in human gastric cancer development and progression. Cancer Res. 2005, 65:2746-2754.
    • (2005) Cancer Res. , vol.65 , pp. 2746-2754
    • Wei, D.1    Gong, W.2    Kanai, M.3    Schlunk, C.4    Wang, L.5    Yao, J.C.6    Wu, T.T.7    Huang, S.8    Xie, K.9
  • 33
    • 83755163788 scopus 로고    scopus 로고
    • Synergistic effects of apigenin and paclitaxel on apoptosis of cancer cells
    • Xu Y., Xin Y., Diao Y., Lu C., Fu J., Luo L., Yin Z. Synergistic effects of apigenin and paclitaxel on apoptosis of cancer cells. PLoS One 2011, 6:29169.
    • (2011) PLoS One , vol.6 , pp. 29169
    • Xu, Y.1    Xin, Y.2    Diao, Y.3    Lu, C.4    Fu, J.5    Luo, L.6    Yin, Z.7
  • 34
    • 0037462796 scopus 로고    scopus 로고
    • Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage
    • Yoon H.S., Chen X., Yang V.W. Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage. J. Biol. Chem. 2003, 278:2101-2105.
    • (2003) J. Biol. Chem. , vol.278 , pp. 2101-2105
    • Yoon, H.S.1    Chen, X.2    Yang, V.W.3
  • 36
    • 79955608022 scopus 로고    scopus 로고
    • Krüppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion
    • Yu F., Li J., Chen H., Fu J., Ray S., Huang S., Zheng H., Ai W. Krüppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion. Oncogene 2011, 30:2161-2172.
    • (2011) Oncogene , vol.30 , pp. 2161-2172
    • Yu, F.1    Li, J.2    Chen, H.3    Fu, J.4    Ray, S.5    Huang, S.6    Zheng, H.7    Ai, W.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.