Loop motion and base release in purine-specific nucleoside hydrolase: A molecular dynamics study

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1834, Issue 6, 2013, Pages 1117-1124

  Chen, Nanhao ^a   Ge, Hu ^a   Xu, Jun ^a   Cao, Zexing ^b   Wu, Ruibo ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b XIAMEN UNIVERSITY   (China)

Author keywords

Base release; Loop motion; Molecular dynamics (MD) simulations; Nucleoside hydrolase; Umbrella sampling

Indexed keywords

ARGININE; BASE; GLUTAMIC ACID; HISTIDINE; NUCLEOSIDASE; RIBOSE; TRYPTOPHAN;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; HYDROGEN BOND; HYDROLYSIS; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN SECRETION; REGULATORY MECHANISM; STATIC ELECTRICITY; THERMODYNAMICS;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HYDROLASES; HYDROLYSIS; KINETICS; MOLECULAR DYNAMICS SIMULATION; PROTEIN STRUCTURE, SECONDARY; PURINES; SUBSTRATE SPECIFICITY; THERMODYNAMICS; TRYPANOSOMA VIVAX;

TRYPANOSOMA VIVAX;

EID: 84878107944     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2013.02.005     Document Type: Article

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