Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1774, Issue 11, 2007, Pages 1451-1461

  Barlow, John N ^a   Steyaert, Jan ^a  

^a FREE UNIVERSITY OF BRUSSELS   (Belgium)

Author keywords

Forward commitment; Nucleoside hydrolase; Solvent isotope effect; Transient kinetic

Indexed keywords

GUANOSINE; INOSINE; NUCLEOSIDASE; WATER;

ARTICLE; CATALYSIS; CHEMICAL BOND; CHEMISTRY; CONCENTRATION (PARAMETERS); ENERGY TRANSFER; FLOW KINETICS; ISOTOPE ANALYSIS; LOW TEMPERATURE; MICHAELIS CONSTANT; MOLECULAR INTERACTION; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; STEADY STATE; TRYPANOSOMA VIVAX;

ANIMALS; BINDING SITES; KINETICS; N-GLYCOSYL HYDROLASES; THERMODYNAMICS; TRYPANOSOMA VIVAX;

TRYPANOSOMA VIVAX;

EID: 36248953674     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2007.08.027     Document Type: Article

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