-
1
-
-
1542317452
-
HIV vaccine design and the neutralizing antibody problem
-
Burton D.R., Desrosiers R.C., Doms R.W., Koff W.C., Kwong P.D., Moore J.P., Nabel G.J., Sodroski J., Wilson I.A., Wyatt R.T. HIV vaccine design and the neutralizing antibody problem. Nat. Immunol. 2004, 5:233-236.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 233-236
-
-
Burton, D.R.1
Desrosiers, R.C.2
Doms, R.W.3
Koff, W.C.4
Kwong, P.D.5
Moore, J.P.6
Nabel, G.J.7
Sodroski, J.8
Wilson, I.A.9
Wyatt, R.T.10
-
3
-
-
21744447837
-
Immunology. Close to the edge: neutralizing the HIV-1 envelope
-
Nabel G.J. Immunology. Close to the edge: neutralizing the HIV-1 envelope. Science 2005, 308:1878-1879.
-
(2005)
Science
, vol.308
, pp. 1878-1879
-
-
Nabel, G.J.1
-
4
-
-
20844448731
-
Antigenic conservation and immunogenicity of the HIV coreceptor binding site
-
Decker J.M., Bibollet-Ruche F., Wei X., Wang S., Levy D.N., Wang W., Delaporte E., Peeters M., Derdeyn C.A., Allen S., Hunter E., Saag M.S., Hoxie J.A., Hahn B.H., Kwong P.D., Robinson J.E., Shaw G.M. Antigenic conservation and immunogenicity of the HIV coreceptor binding site. J. Exp. Med. 2005, 201:1407-1419.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1407-1419
-
-
Decker, J.M.1
Bibollet-Ruche, F.2
Wei, X.3
Wang, S.4
Levy, D.N.5
Wang, W.6
Delaporte, E.7
Peeters, M.8
Derdeyn, C.A.9
Allen, S.10
Hunter, E.11
Saag, M.S.12
Hoxie, J.A.13
Hahn, B.H.14
Kwong, P.D.15
Robinson, J.E.16
Shaw, G.M.17
-
5
-
-
0037456827
-
Antibody neutralization and escape by HIV-1
-
Wei X., Decker J.M., Wang S., Hui H., Kappes J.C., Wu X., Salazar-Gonzalez J.F., Salazar M.G., Kilby J.M., Saag M.S., Komarova N.L., Nowak M.A., Hahn B.H., Kwong P.D., Shaw G.M. Antibody neutralization and escape by HIV-1. Nature 2003, 422:307-312.
-
(2003)
Nature
, vol.422
, pp. 307-312
-
-
Wei, X.1
Decker, J.M.2
Wang, S.3
Hui, H.4
Kappes, J.C.5
Wu, X.6
Salazar-Gonzalez, J.F.7
Salazar, M.G.8
Kilby, J.M.9
Saag, M.S.10
Komarova, N.L.11
Nowak, M.A.12
Hahn, B.H.13
Kwong, P.D.14
Shaw, G.M.15
-
6
-
-
21344434534
-
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies
-
Haynes B.F., Fleming J., St Clair E.W., Katinger H., Stiegler G., Kunert R., Robinson J., Scearce R.M., Plonk K., Staats H.F., Ortel T.L., Liao H.X., Alam S.M. Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies. Science 2005, 308:1906-1908.
-
(2005)
Science
, vol.308
, pp. 1906-1908
-
-
Haynes, B.F.1
Fleming, J.2
St Clair, E.W.3
Katinger, H.4
Stiegler, G.5
Kunert, R.6
Robinson, J.7
Scearce, R.M.8
Plonk, K.9
Staats, H.F.10
Ortel, T.L.11
Liao, H.X.12
Alam, S.M.13
-
7
-
-
80053132436
-
Broad neutralization coverage of HIV by multiple highly potent antibodies
-
Walker L.M., Huber M., Doores K.J., Falkowska E., Pejchal R., Julien J.P., Wang S.K., Ramos A., Chan-Hui P.Y., Moyle M., Mitcham J.L., Hammond P.W., Olsen O.A., Phung P., Fling S., Wong C.H., Phogat S., Wrin T., Simek M.D., Koff W.C., Wilson I.A., Burton D.R., Poignard P. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature 2011, 477:466-470.
-
(2011)
Nature
, vol.477
, pp. 466-470
-
-
Walker, L.M.1
Huber, M.2
Doores, K.J.3
Falkowska, E.4
Pejchal, R.5
Julien, J.P.6
Wang, S.K.7
Ramos, A.8
Chan-Hui, P.Y.9
Moyle, M.10
Mitcham, J.L.11
Hammond, P.W.12
Olsen, O.A.13
Phung, P.14
Fling, S.15
Wong, C.H.16
Phogat, S.17
Wrin, T.18
Simek, M.D.19
Koff, W.C.20
Wilson, I.A.21
Burton, D.R.22
Poignard, P.23
more..
-
8
-
-
82255179322
-
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield
-
Pejchal R., Doores K.J., Walker L.M., Khayat R., Huang P.S., Wang S.K., Stanfield R.L., Julien J.P., Ramos A., Crispin M., Depetris R., Katpally U., Marozsan A., Cupo A., Maloveste S., Liu Y., McBride R., Ito Y., Sanders R.W., Ogohara C., Paulson J.C., Feizi T., Scanlan C.N., Wong C.H., Moore J.P., Olson W.C., Ward A.B., Poignard P., Schief W.R., Burton D.R., Wilson I.A. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science 2011, 334:1097-1103.
-
(2011)
Science
, vol.334
, pp. 1097-1103
-
-
Pejchal, R.1
Doores, K.J.2
Walker, L.M.3
Khayat, R.4
Huang, P.S.5
Wang, S.K.6
Stanfield, R.L.7
Julien, J.P.8
Ramos, A.9
Crispin, M.10
Depetris, R.11
Katpally, U.12
Marozsan, A.13
Cupo, A.14
Maloveste, S.15
Liu, Y.16
McBride, R.17
Ito, Y.18
Sanders, R.W.19
Ogohara, C.20
Paulson, J.C.21
Feizi, T.22
Scanlan, C.N.23
Wong, C.H.24
Moore, J.P.25
Olson, W.C.26
Ward, A.B.27
Poignard, P.28
Schief, W.R.29
Burton, D.R.30
Wilson, I.A.31
more..
-
9
-
-
12144290520
-
Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
-
Huang C.C., Venturi M., Majeed S., Moore M.J., Phogat S., Zhang M.Y., Dimitrov D.S., Hendrickson W.A., Robinson J., Sodroski J., Wyatt R., Choe H., Farzan M., Kwong P.D. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:2706-2711.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 2706-2711
-
-
Huang, C.C.1
Venturi, M.2
Majeed, S.3
Moore, M.J.4
Phogat, S.5
Zhang, M.Y.6
Dimitrov, D.S.7
Hendrickson, W.A.8
Robinson, J.9
Sodroski, J.10
Wyatt, R.11
Choe, H.12
Farzan, M.13
Kwong, P.D.14
-
10
-
-
27744597054
-
Structure of a V3-containing HIV-1 gp120 core
-
Huang C.C., Tang M., Zhang M.Y., Majeed S., Montabana E., Stanfield R.L., Dimitrov D.S., Korber B., Sodroski J., Wilson I.A., Wyatt R., Kwong P.D. Structure of a V3-containing HIV-1 gp120 core. Science 2005, 310:1025-1028.
-
(2005)
Science
, vol.310
, pp. 1025-1028
-
-
Huang, C.C.1
Tang, M.2
Zhang, M.Y.3
Majeed, S.4
Montabana, E.5
Stanfield, R.L.6
Dimitrov, D.S.7
Korber, B.8
Sodroski, J.9
Wilson, I.A.10
Wyatt, R.11
Kwong, P.D.12
-
11
-
-
0032543307
-
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
-
Kwong P.D., Wyatt R., Robinson J., Sweet R.W., Sodroski J., Hendrickson W.A. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 1998, 393:648-659.
-
(1998)
Nature
, vol.393
, pp. 648-659
-
-
Kwong, P.D.1
Wyatt, R.2
Robinson, J.3
Sweet, R.W.4
Sodroski, J.5
Hendrickson, W.A.6
-
12
-
-
0030006070
-
Clonal selection and learning in the antibody system
-
Rajewsky K. Clonal selection and learning in the antibody system. Nature 1996, 381:751-758.
-
(1996)
Nature
, vol.381
, pp. 751-758
-
-
Rajewsky, K.1
-
13
-
-
0036240127
-
The mechanism and regulation of chromosomal V(D)J recombination
-
Bassing C.H., Swat W., Alt F.W. The mechanism and regulation of chromosomal V(D)J recombination. Cell 2002, 109:S45-S55.
-
(2002)
Cell
, vol.109
-
-
Bassing, C.H.1
Swat, W.2
Alt, F.W.3
-
14
-
-
80355122714
-
V(D)J recombination: mechanisms of initiation
-
Schatz D.G., Swanson P.C. V(D)J recombination: mechanisms of initiation. Annu. Rev. Genet. 2011, 45:167-202.
-
(2011)
Annu. Rev. Genet.
, vol.45
, pp. 167-202
-
-
Schatz, D.G.1
Swanson, P.C.2
-
15
-
-
0032442391
-
Immune receptor editing: revise and select
-
Nussenzweig M.C. Immune receptor editing: revise and select. Cell 1998, 95:875-878.
-
(1998)
Cell
, vol.95
, pp. 875-878
-
-
Nussenzweig, M.C.1
-
16
-
-
0034608364
-
Revising B cell receptors
-
Nemazee D., Weigert M. Revising B cell receptors. J. Exp. Med. 2000, 191:1813-1817.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1813-1817
-
-
Nemazee, D.1
Weigert, M.2
-
18
-
-
33847160642
-
H replacement in mice and humans
-
H replacement in mice and humans. Trends Immunol. 2007, 28:132-137.
-
(2007)
Trends Immunol.
, vol.28
, pp. 132-137
-
-
Zhang, Z.1
-
19
-
-
0038579618
-
H gene replacement
-
H gene replacement. Ann. N. Y. Acad. Sci. 2003, 987:270-273.
-
(2003)
Ann. N. Y. Acad. Sci.
, vol.987
, pp. 270-273
-
-
Zhang, Z.1
Wang, Y.H.2
Zemlin, M.3
Findley, H.W.4
Bridges, S.L.5
Burrows, P.D.6
Cooper, M.D.7
-
20
-
-
0038783610
-
H gene replacement to the primary B cell repertoire
-
H gene replacement to the primary B cell repertoire. Immunity 2003, 19:21-31.
-
(2003)
Immunity
, vol.19
, pp. 21-31
-
-
Zhang, Z.1
Zemlin, M.2
Wang, Y.-H.3
Munfus, D.4
Huye, L.E.5
Findley, H.W.6
Bridges, S.L.7
Roth, D.B.8
Burrows, P.D.9
Cooper, M.D.10
-
21
-
-
0029553058
-
Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing
-
Chen C., Nagy Z., Prak E.L., Weigert M. Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing. Immunity 1995, 3:747-755.
-
(1995)
Immunity
, vol.3
, pp. 747-755
-
-
Chen, C.1
Nagy, Z.2
Prak, E.L.3
Weigert, M.4
-
22
-
-
0028850944
-
The site and stage of anti-DNA B-cell deletion
-
Chen C., Nagy Z., Radic M.Z., Hardy R.R., Huszar D., Camper S.A., Weigert M. The site and stage of anti-DNA B-cell deletion. Nature 1995, 373:252-255.
-
(1995)
Nature
, vol.373
, pp. 252-255
-
-
Chen, C.1
Nagy, Z.2
Radic, M.Z.3
Hardy, R.R.4
Huszar, D.5
Camper, S.A.6
Weigert, M.7
-
23
-
-
0030997499
-
Editing disease-associated autoantibodies
-
Chen C., Prak E.L., Weigert M. Editing disease-associated autoantibodies. Immunity 1997, 6:97-105.
-
(1997)
Immunity
, vol.6
, pp. 97-105
-
-
Chen, C.1
Prak, E.L.2
Weigert, M.3
-
24
-
-
0031573516
-
VH gene replacement in hyperselected B cells of the quasimonoclonal mouse
-
Cascalho M., Wong J., Wabl M. VH gene replacement in hyperselected B cells of the quasimonoclonal mouse. J. Immunol. 1997, 159:5795-5801.
-
(1997)
J. Immunol.
, vol.159
, pp. 5795-5801
-
-
Cascalho, M.1
Wong, J.2
Wabl, M.3
-
25
-
-
0344689840
-
Secondary rearrangements and hypermutation generate sufficient B cell diversity to mount protective antiviral immunoglobulin responses
-
Lopez-Macias C., Kalinke U., Cascalho M., Wabl M., Hengartner H., Zinkernagel R.M., Lamarre A. Secondary rearrangements and hypermutation generate sufficient B cell diversity to mount protective antiviral immunoglobulin responses. J. Exp. Med. 1999, 189:1791-1798.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1791-1798
-
-
Lopez-Macias, C.1
Kalinke, U.2
Cascalho, M.3
Wabl, M.4
Hengartner, H.5
Zinkernagel, R.M.6
Lamarre, A.7
-
26
-
-
33746004544
-
Antibody repertoires generated by VH replacement and direct VH to JH joining
-
Koralov S.B., Novobrantseva T.I., Konigsmann J., Ehlich A., Rajewsky K. Antibody repertoires generated by VH replacement and direct VH to JH joining. Immunity 2006, 25:43-53.
-
(2006)
Immunity
, vol.25
, pp. 43-53
-
-
Koralov, S.B.1
Novobrantseva, T.I.2
Konigsmann, J.3
Ehlich, A.4
Rajewsky, K.5
-
27
-
-
0026592314
-
Immunoglobulin VH clan and family identity predicts variable domain structure and may influence antigen binding
-
Kirkham P.M., Mortari F., Newton J.A., Schroeder H.W. Immunoglobulin VH clan and family identity predicts variable domain structure and may influence antigen binding. EMBO J. 1992, 11:603-609.
-
(1992)
EMBO J.
, vol.11
, pp. 603-609
-
-
Kirkham, P.M.1
Mortari, F.2
Newton, J.A.3
Schroeder, H.W.4
-
28
-
-
0033954256
-
The Protein Data Bank
-
Berman H.M., Westbrook J., Feng Z., Gilliland G., Bhat T.N., Weissig H., Shindyalov I.N., Bourne P.E. The Protein Data Bank. Nucleic Acids Res. 2000, 28:235-242.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
Weissig, H.6
Shindyalov, I.N.7
Bourne, P.E.8
-
29
-
-
0027136282
-
Comparative protein modelling by satisfaction of spatial restraints
-
Sali A., Blundell T.L. Comparative protein modelling by satisfaction of spatial restraints. J. Mol. Biol. 1993, 234:779-815.
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
30
-
-
0242551578
-
Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures
-
Zemlin M., Klinger M., Link J., Zemlin C., Bauer K., Engler J.A., Schroeder H.W., Kirkham P.M. Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures. J. Mol. Biol. 2003, 334:733-749.
-
(2003)
J. Mol. Biol.
, vol.334
, pp. 733-749
-
-
Zemlin, M.1
Klinger, M.2
Link, J.3
Zemlin, C.4
Bauer, K.5
Engler, J.A.6
Schroeder, H.W.7
Kirkham, P.M.8
-
31
-
-
0022502863
-
Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma
-
Kleinfield R., Hardy R.R., Tarlinton D., Dangl J., Herzenberg L.A., Weigert M. Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma. Nature 1986, 322:843-846.
-
(1986)
Nature
, vol.322
, pp. 843-846
-
-
Kleinfield, R.1
Hardy, R.R.2
Tarlinton, D.3
Dangl, J.4
Herzenberg, L.A.5
Weigert, M.6
-
32
-
-
0022557584
-
H joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production
-
H joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production. Nature 1986, 322:840-842.
-
(1986)
Nature
, vol.322
, pp. 840-842
-
-
Reth, M.1
Gehrmann, P.2
Petrac, E.3
Wiese, P.4
-
33
-
-
33750836920
-
VH replacement rescues progenitor B cells with two nonproductive VDJ alleles
-
Lutz J., Muller W., Jack H.M. VH replacement rescues progenitor B cells with two nonproductive VDJ alleles. J. Immunol. 2006, 177:7007-7014.
-
(2006)
J. Immunol.
, vol.177
, pp. 7007-7014
-
-
Lutz, J.1
Muller, W.2
Jack, H.M.3
|