메뉴 건너뛰기




Volumn 19, Issue 6, 2013, Pages 811-827

Splicing kinetics and transcript release from the chromatin compartment limit the rate of Lipid A-induced gene expression

Author keywords

Gene expression; Inflammatory response; mRNA maturation; Pre mRNA splicing; Splicing kinetics

Indexed keywords

LIPID A;

EID: 84878044937     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.039081.113     Document Type: Article
Times cited : (79)

References (88)
  • 1
    • 33748933029 scopus 로고    scopus 로고
    • 3′-End formation signals modulate the association of genes with the nuclear periphery as well as mRNP dot formation
    • DOI 10.1038/sj.emboj.7601305, PII 7601305
    • Abruzzi KC, Belostotsky DA, Chekanova JA, Dower K, Rosbash M. 2006. 3′-end formation signals modulate the association of genes with the nuclear periphery as well as mRNP dot formation. EMBO J 25: 4253-4262. (Pubitemid 44435223)
    • (2006) EMBO Journal , vol.25 , Issue.18 , pp. 4253-4262
    • Abruzzi, K.C.1    Belostotsky, D.A.2    Chekanova, J.A.3    Dower, K.4    Rosbash, M.5
  • 2
    • 78649301379 scopus 로고    scopus 로고
    • RiboSys, a high-resolution, quantitative approach to measure the in vivo kinetics of pre-mRNA splicing and 3′-end processing in Saccharomyces cerevisiae
    • Alexander RD, Barrass JD, Dichtl B, Kos M, Obtulowicz T, Robert MC, Koper M, Karkusiewicz I, Mariconti L, Tollervey D, et al. 2010a. RiboSys, a high-resolution, quantitative approach to measure the in vivo kinetics of pre-mRNA splicing and 3′-end processing in Saccharomyces cerevisiae. RNA 16: 2570-2580.
    • (2010) RNA , vol.16 , pp. 2570-2580
    • Alexander, R.D.1    Barrass, J.D.2    Dichtl, B.3    Kos, M.4    Obtulowicz, T.5    Robert, M.C.6    Koper, M.7    Karkusiewicz, I.8    Mariconti, L.9    Tollervey, D.10
  • 5
    • 70350783881 scopus 로고    scopus 로고
    • Tracking rates of transcription and splicing in vivo
    • Ardehali MB, Lis JT. 2009. Tracking rates of transcription and splicing in vivo. Nat Struct Mol Biol 16: 1123-1124.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 1123-1124
    • Ardehali, M.B.1    Lis, J.T.2
  • 6
    • 0027957779 scopus 로고
    • Splicing of Balbiani ring 1 gene pre-mRNA occurs simultaneously with transcription
    • DOI 10.1016/0092-8674(94)90182-1
    • Bauren G, Wieslander L. 1994. Splicing of Balbiani ring 1 gene pre-mRNA occurs simultaneously with transcription. Cell 76: 183-192. (Pubitemid 24035291)
    • (1994) Cell , vol.76 , Issue.1 , pp. 183-192
    • Bauren, G.1    Wieslander, L.2
  • 9
    • 28444438876 scopus 로고    scopus 로고
    • Ribozyme cleavage reveals connections between mRNA release from the site of transcription and pre-mRNA processing
    • DOI 10.1016/j.molcel.2005.11.009, PII S1097276505017697
    • Bird G, Fong N, Gatlin JC, Farabaugh S, Bentley DL. 2005. Ribozyme cleavage reveals connections between mRNA release from the site of transcription and pre-mRNA processing. Mol Cell 20: 747-758. (Pubitemid 41740696)
    • (2005) Molecular Cell , vol.20 , Issue.5 , pp. 747-758
    • Bird, G.1    Fong, N.2    Gatlin, J.C.3    Farabaugh, S.4    Bentley, D.L.5
  • 12
    • 22144486964 scopus 로고    scopus 로고
    • Subdivision of large introns in Drosophila by recursive splicing at nonexonic elements
    • DOI 10.1534/genetics.104.039701
    • Burnette JM, Miyamoto-Sato E, Schaub MA, Conklin J, Lopez AJ. 2005. Subdivision of large introns in Drosophila by recursive splicing at nonexonic elements. Genetics 170: 661-674. (Pubitemid 40980668)
    • (2005) Genetics , vol.170 , Issue.2 , pp. 661-674
    • Burnette, J.M.1    Miyamoto-Sato, E.2    Schaub, M.A.3    Conklin, J.4    Lopez, A.J.5
  • 13
    • 78649289872 scopus 로고    scopus 로고
    • Global analysis of nascent RNA reveals transcriptional pausing in terminal exons
    • Carrillo Oesterreich F, Preibisch S, Neugebauer KM. 2010. Global analysis of nascent RNA reveals transcriptional pausing in terminal exons. Mol Cell 40: 571-581.
    • (2010) Mol Cell , vol.40 , pp. 571-581
    • Carrillo Oesterreich, F.1    Preibisch, S.2    Neugebauer, K.M.3
  • 14
    • 84857761249 scopus 로고    scopus 로고
    • Pre-mRNA 3′-end processing complex assembly and function
    • Chan S, Choi EA, Shi Y. 2011. Pre-mRNA 3′-end processing complex assembly and function. Wiley Interdiscip Rev RNA 2: 321-335.
    • (2011) Wiley Interdiscip Rev RNA , vol.2 , pp. 321-335
    • Chan, S.1    Choi, E.A.2    Shi, Y.3
  • 15
    • 0031453408 scopus 로고    scopus 로고
    • mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain
    • Cho EJ, Takagi T, Moore CR, Buratowski S. 1997. mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev 11: 3319-3326. (Pubitemid 28023956)
    • (1997) Genes and Development , vol.11 , Issue.24 , pp. 3319-3326
    • Cho, E.-J.1    Takagi, T.2    Moore, C.R.3    Buratowski, S.4
  • 16
    • 57849109058 scopus 로고    scopus 로고
    • Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters
    • Core LJ, Waterfall JJ, Lis JT. 2008. Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters. Science 322: 1845-1848.
    • (2008) Science , vol.322 , pp. 1845-1848
    • Core, L.J.1    Waterfall, J.J.2    Lis, J.T.3
  • 17
    • 0041013167 scopus 로고    scopus 로고
    • Inefficient processing impairs release of RNA from the site of transcription
    • DOI 10.1093/emboj/18.10.2855
    • Custodio N, Carmo-Fonseca M, Geraghty F, Pereira HS, Grosveld F, Antoniou M. 1999. Inefficient processing impairs release of RNA from the site of transcription. EMBO J 18: 2855-2866. (Pubitemid 29233957)
    • (1999) EMBO Journal , vol.18 , Issue.10 , pp. 2855-2866
    • Custodio, N.1    Carmo-Fonseca, M.2    Geraghty, F.3    Pereira, H.S.4    Grosveld, F.5    Antoniou, M.6
  • 19
    • 84875429298 scopus 로고    scopus 로고
    • Reflections on the history of pre-mRNA processing and highlights of current knowledge: A unified picture
    • Darnell JE Jr. 2013. Reflections on the history of pre-mRNA processing and highlights of current knowledge: A unified picture. RNA 19: 443-460.
    • (2013) RNA , vol.19 , pp. 443-460
    • Darnell Jr., J.E.1
  • 21
    • 77951200179 scopus 로고    scopus 로고
    • First come, first served revisited: Factors affecting the same alternative splicing event have different effects on the relative rates of intron removal
    • de la Mata M, Lafaille C, Kornblihtt AR. 2010. First come, first served revisited: Factors affecting the same alternative splicing event have different effects on the relative rates of intron removal. RNA 16: 904-912.
    • (2010) RNA , vol.16 , pp. 904-912
    • De La Mata, M.1    Lafaille, C.2    Kornblihtt, A.R.3
  • 23
    • 0016318515 scopus 로고
    • Relationship of chain transcription to poly(A) addition and processing of hnRNA in HeLa cells
    • Derman E, Darnell JE. 1974. Relationship of chain transcription to poly(A) addition and processing of hnRNA in HeLa cells. Cell 3: 255-264.
    • (1974) Cell , vol.3 , pp. 255-264
    • Derman, E.1    Darnell, J.E.2
  • 24
    • 84880317039 scopus 로고    scopus 로고
    • A role for TREX components in the release of spliced mRNA from nuclear speckle domains
    • Dias AP, Dufu K, Lei H, Reed R. 2010. A role for TREX components in the release of spliced mRNA from nuclear speckle domains. Nat Commun 1: 97.
    • (2010) Nat Commun , vol.1 , pp. 97
    • Dias, A.P.1    Dufu, K.2    Lei, H.3    Reed, R.4
  • 26
    • 60549104588 scopus 로고    scopus 로고
    • Splice-site pairing is an intrinsically high fidelity process
    • Fox-Walsh KL, Hertel KJ. 2009. Splice-site pairing is an intrinsically high fidelity process. Proc Natl Acad Sci 106: 1766-1771.
    • (2009) Proc Natl Acad Sci , vol.106 , pp. 1766-1771
    • Fox-Walsh, K.L.1    Hertel, K.J.2
  • 29
    • 77955801615 scopus 로고    scopus 로고
    • Galaxy: A comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
    • Goecks J, Nekrutenko A, Taylor J. 2010. Galaxy: A comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences. Genome Biol 11: R86.
    • (2010) Genome Biol , vol.11
    • Goecks, J.1    Nekrutenko, A.2    Taylor, J.3
  • 30
    • 77957370148 scopus 로고    scopus 로고
    • In vivo imaging of labelled endogenous β-actin mRNA during nucleocytoplasmic transport
    • Grunwald D, Singer RH. 2010. In vivo imaging of labelled endogenous β-actin mRNA during nucleocytoplasmic transport. Nature 467: 604-607.
    • (2010) Nature , vol.467 , pp. 604-607
    • Grunwald, D.1    Singer, R.H.2
  • 31
    • 0018385738 scopus 로고
    • The synthesis and processing of a nuclear RNA precursor to rat pregrowth hormone messenger RNA
    • Harpold MM, Dobner PR, Evans R, Bancroft FC, Darnell JE Jr. 1979. The synthesis and processing of a nuclear RNA precursor to rat pregrowth hormone messenger RNA. Nucleic Acids Res 6: 3133-3144. (Pubitemid 9222562)
    • (1979) Nucleic Acids Research , vol.6 , Issue.9 , pp. 3133-3144
    • Harpold, M.M.1    Dobner, P.R.2    Evans, R.3
  • 32
    • 0032247577 scopus 로고    scopus 로고
    • Generation of alternative Ultrabithorax isoforms and stepwise removal of a large intron by resplicing at exon-exon junctions
    • Hatton AR, Subramaniam V, Lopez AJ. 1998. Generation of alternative Ultrabithorax isoforms and stepwise removal of a large intron by resplicing at exon-exon junctions. Mol Cell 2: 787-796. (Pubitemid 128378986)
    • (1998) Molecular Cell , vol.2 , Issue.6 , pp. 787-796
    • Hatton, A.R.1    Subramaniam, V.2    Lopez, A.J.3
  • 33
    • 0031990320 scopus 로고    scopus 로고
    • The Function of Multisite Splicing Enhancers
    • Hertel KJ, Maniatis T. 1998. The function of multisite splicing enhancers. Mol Cell 1: 449-455. (Pubitemid 128378893)
    • (1998) Molecular Cell , vol.1 , Issue.3 , pp. 449-455
    • Hertel, K.J.1    Maniatis, T.2
  • 35
    • 77950643284 scopus 로고    scopus 로고
    • Competing upstream 5′ splice sites enhance the rate of proximal splicing
    • Hicks MJ, Mueller WF, Shepard PJ, Hertel KJ. 2010. Competing upstream 5′ splice sites enhance the rate of proximal splicing. Mol Cell Biol 30: 1878-1886.
    • (2010) Mol Cell Biol , vol.30 , pp. 1878-1886
    • Hicks, M.J.1    Mueller, W.F.2    Shepard, P.J.3    Hertel, K.J.4
  • 37
    • 84867160564 scopus 로고    scopus 로고
    • The RNA polymerase II CTD coordinates transcription and RNA processing
    • Hsin JP, Manley JL. 2012. The RNA polymerase II CTD coordinates transcription and RNA processing. Genes Dev 26: 2119-2137.
    • (2012) Genes Dev , vol.26 , pp. 2119-2137
    • Hsin, J.P.1    Manley, J.L.2
  • 38
    • 17044427579 scopus 로고    scopus 로고
    • Serine/arginine-rich protein-dependent suppression of exon skipping by exonic splicing enhancers
    • Ibrahim EC, Schaal TD, Hertel KJ, Reed R, Maniatis T. 2005. Serine/arginine-rich protein-dependent suppression of exon skipping by exonic splicing enhancers. Proc Natl Acad Sci 102: 5002-5007.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 5002-5007
    • Ibrahim, E.C.1    Schaal, T.D.2    Hertel, K.J.3    Reed, R.4    Maniatis, T.5
  • 39
    • 0035022577 scopus 로고    scopus 로고
    • A block to mRNA nuclear export in S. cerevisiae leads to hyperadenylation of transcripts that accumulate at the site of transcription
    • DOI 10.1016/S1097-2765(01)00232-5
    • Jensen TH, Patricio K, McCarthy T, Rosbash M. 2001. A block to mRNA nuclear export in S. cerevisiae leads to hyperadenylation of transcripts that accumulate at the site of transcription. Mol Cell 7: 887-898. (Pubitemid 32436448)
    • (2001) Molecular Cell , vol.7 , Issue.4 , pp. 887-898
    • Jensen, T.H.1    Patricio, K.2    McCarthy, T.3    Rosbash, M.4
  • 40
    • 0030013179 scopus 로고    scopus 로고
    • Inhibition by SR proteins splicing of a regulated adenovirus pre-mRNA
    • DOI 10.1038/381535a0
    • Kanopka A, Muhlemann O, Akusjarvi G. 1996. Inhibition by SR proteins of splicing of a regulated adenovirus pre-mRNA. Nature 381: 535-538. (Pubitemid 26170934)
    • (1996) Nature , vol.381 , Issue.6582 , pp. 535-538
    • Kanopka, A.1    Muhlemann, O.2    Akusjarvi, G.3
  • 41
    • 0027495952 scopus 로고
    • Order of intron removal during splicing of endogenous adenine phosphoribosyltransferase and dihydrofolate reductase pre-mRNA
    • Kessler O, Jiang Y, Chasin LA. 1993. Order of intron removal during splicing of endogenous adenine phosphoribosyltransferase and dihydrofolate reductase pre-mRNA. Mol Cell Biol 13: 6211-6222. (Pubitemid 23292615)
    • (1993) Molecular and Cellular Biology , vol.13 , Issue.10 , pp. 6211-6222
    • Kessler, O.1    Jiang, Y.2    Chasin, L.A.3
  • 43
    • 84869859046 scopus 로고    scopus 로고
    • Cotranscriptional splicing efficiency differs dramatically between Drosophila and mouse
    • Khodor YL, Menet JS, Tolan M, Rosbash M. 2012. Cotranscriptional splicing efficiency differs dramatically between Drosophila and mouse. RNA 18: 2174-2186.
    • (2012) RNA , vol.18 , pp. 2174-2186
    • Khodor, Y.L.1    Menet, J.S.2    Tolan, M.3    Rosbash, M.4
  • 44
    • 33846945735 scopus 로고    scopus 로고
    • Processing of intronic microRNAs
    • Kim YK, Kim VN. 2007. Processing of intronic microRNAs. EMBO J 26: 775-783.
    • (2007) EMBO J , vol.26 , pp. 775-783
    • Kim, Y.K.1    Kim, V.N.2
  • 45
    • 59449100357 scopus 로고    scopus 로고
    • Spliceosome assembly pathways for different types of alternative splicing converge during commitment to splice site pairing in the A complex
    • Kotlajich MV, Crabb TL, Hertel KJ. 2009. Spliceosome assembly pathways for different types of alternative splicing converge during commitment to splice site pairing in the A complex. Mol Cell Biol 29: 1072-1082.
    • (2009) Mol Cell Biol , vol.29 , pp. 1072-1082
    • Kotlajich, M.V.1    Crabb, T.L.2    Hertel, K.J.3
  • 46
    • 33746630487 scopus 로고    scopus 로고
    • In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants
    • DOI 10.1101/gad.1434706
    • Lacadie SA, Tardiff DF, Kadener S, Rosbash M. 2006. In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants. Genes Dev 20: 2055-2066. (Pubitemid 44157457)
    • (2006) Genes and Development , vol.20 , Issue.15 , pp. 2055-2066
    • Lacadie, S.A.1    Tardiff, D.F.2    Kadener, S.3    Rosbash, M.4
  • 47
    • 0025169502 scopus 로고
    • Splicing precedes polyadenylation during Drosophila E74A transcription
    • LeMaire MF, Thummel CS. 1990. Splicing precedes polyadenylation during Drosophila E74A transcription. Mol Cell Biol 10: 6059-6063.
    • (1990) Mol Cell Biol , vol.10 , pp. 6059-6063
    • LeMaire, M.F.1    Thummel, C.S.2
  • 49
    • 4143078172 scopus 로고    scopus 로고
    • Commitment to splice site pairing coincides with a complex formation
    • DOI 10.1016/j.molcel.2004.06.025, PII S1097276504003739
    • Lim SR, Hertel KJ. 2004. Commitment to splice site pairing coincides with A complex formation. Mol Cell 15: 477-483. (Pubitemid 39092762)
    • (2004) Molecular Cell , vol.15 , Issue.3 , pp. 477-483
    • Lim, S.R.1    Hertel, K.J.2
  • 50
    • 33748351186 scopus 로고    scopus 로고
    • Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells
    • DOI 10.1038/nsmb1135, PII NSMB1135
    • Listerman I, Sapra AK, Neugebauer KM. 2006. Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells. Nat Struct Mol Biol 13: 815-822. (Pubitemid 44338776)
    • (2006) Nature Structural and Molecular Biology , vol.13 , Issue.9 , pp. 815-822
    • Listerman, I.1    Sapra, A.K.2    Neugebauer, K.M.3
  • 51
    • 10244239317 scopus 로고    scopus 로고
    • Consequences of regulated pre-mRNA splicing in the immune system
    • DOI 10.1038/nri1497
    • Lynch KW. 2004. Consequences of regulated pre-mRNA splicing in the immune system. Nat Rev Immunol 4: 931-940. (Pubitemid 39620068)
    • (2004) Nature Reviews Immunology , vol.4 , Issue.12 , pp. 931-940
    • Lynch, K.W.1
  • 53
    • 42449158952 scopus 로고    scopus 로고
    • Spliceosome assembly and composition
    • Matlin AJ, Moore MJ. 2007. Spliceosome assembly and composition. Adv Exp Med Biol 623: 14-35.
    • (2007) Adv Exp Med Biol , vol.623 , pp. 14-35
    • Matlin, A.J.1    Moore, M.J.2
  • 55
    • 0018233483 scopus 로고
    • + nuclear sequences are conserved and poly(A) addition precedes splicing
    • + nuclear sequences are conserved and poly(A) addition precedes splicing. Cell 15: 1477-1493.
    • (1978) Cell , vol.15 , pp. 1477-1493
    • Nevins, J.R.1    Darnell Jr., J.E.2
  • 56
    • 80053932983 scopus 로고    scopus 로고
    • Stress-responsive maturation of Clk1/4 pre-mRNAs promotes phosphorylation of SR splicing factor
    • Ninomiya K, Kataoka N, Hagiwara M. 2011. Stress-responsive maturation of Clk1/4 pre-mRNAs promotes phosphorylation of SR splicing factor. J Cell Biol 195: 27-40.
    • (2011) J Cell Biol , vol.195 , pp. 27-40
    • Ninomiya, K.1    Kataoka, N.2    Hagiwara, M.3
  • 57
    • 0022160149 scopus 로고
    • RNP particles at splice junction sequences on Drosophila chorion transcripts
    • Osheim YN, Miller OL Jr, Beyer AL. 1985. RNP particles at splice junction sequences on Drosophila chorion transcripts. Cell 43: 143-151.
    • (1985) Cell , vol.43 , pp. 143-151
    • Osheim, Y.N.1    Miller Jr., O.L.2    Beyer, A.L.3
  • 58
    • 56749098074 scopus 로고    scopus 로고
    • Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
    • Pan Q, Shai O, Lee LJ, Frey BJ, Blencowe BJ. 2008. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nat Genet 40: 1413-1415.
    • (2008) Nat Genet , vol.40 , pp. 1413-1415
    • Pan, Q.1    Shai, O.2    Lee, L.J.3    Frey, B.J.4    Blencowe, B.J.5
  • 59
    • 84857745166 scopus 로고    scopus 로고
    • Pre-mRNA splicing during transcription in the mammalian system
    • Pandya-Jones A. 2011. Pre-mRNA splicing during transcription in the mammalian system. Wiley Interdiscip Rev RNA 2: 700-717.
    • (2011) Wiley Interdiscip Rev RNA , vol.2 , pp. 700-717
    • Pandya-Jones, A.1
  • 60
    • 70349125488 scopus 로고    scopus 로고
    • Co-transcriptional splicing of constitutive and alternative exons
    • Pandya-Jones A, Black DL. 2009. Co-transcriptional splicing of constitutive and alternative exons. RNA 15: 1896-1908.
    • (2009) RNA , vol.15 , pp. 1896-1908
    • Pandya-Jones, A.1    Black, D.L.2
  • 61
    • 47549105524 scopus 로고    scopus 로고
    • Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production
    • DOI 10.1083/jcb.200803111
    • Pawlicki JM, Steitz JA. 2008. Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production. J Cell Biol 182: 61-76. (Pubitemid 352008622)
    • (2008) Journal of Cell Biology , vol.182 , Issue.1 , pp. 61-76
    • Pawlicki, J.M.1    Steitz, J.A.2
  • 62
    • 70350005395 scopus 로고    scopus 로고
    • "Cotranscriptionality": The transcription elongation complex as a nexus for nuclear transactions
    • Perales R, Bentley D. 2009. "Cotranscriptionality": The transcription elongation complex as a nexus for nuclear transactions. Mol Cell 36: 178-191.
    • (2009) Mol Cell , vol.36 , pp. 178-191
    • Perales, R.1    Bentley, D.2
  • 63
    • 77951770756 scopus 로고    scopus 로고
    • BEDTools: A flexible suite of utilities for comparing genomic features
    • Quinlan AR, Hall IM. 2010. BEDTools: A flexible suite of utilities for comparing genomic features. Bioinformatics 26: 841-842.
    • (2010) Bioinformatics , vol.26 , pp. 841-842
    • Quinlan, A.R.1    Hall, I.M.2
  • 66
    • 65249151979 scopus 로고    scopus 로고
    • Polyadenylation releases mRNA from RNA polymerase II in a process that is licensed by splicing
    • Rigo F, Martinson HG. 2009. Polyadenylation releases mRNA from RNA polymerase II in a process that is licensed by splicing. RNA 15: 823-836.
    • (2009) RNA , vol.15 , pp. 823-836
    • Rigo, F.1    Martinson, H.G.2
  • 69
    • 84856218082 scopus 로고    scopus 로고
    • Nuclear quality control of RNA polymerase II transcripts
    • Schmid M, Jensen TH. 2010. Nuclear quality control of RNA polymerase II transcripts. Wiley Interdiscip Rev RNA 1: 474-485.
    • (2010) Wiley Interdiscip Rev RNA , vol.1 , pp. 474-485
    • Schmid, M.1    Jensen, T.H.2
  • 70
    • 79959450181 scopus 로고    scopus 로고
    • Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: Implications for alternative splicing regulation
    • Schmidt U, Basyuk E, Robert MC, Yoshida M, Villemin JP, Auboeuf D, Aitken S, Bertrand E. 2011. Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: Implications for alternative splicing regulation. J Cell Biol 193: 819-829.
    • (2011) J Cell Biol , vol.193 , pp. 819-829
    • Schmidt, U.1    Basyuk, E.2    Robert, M.C.3    Yoshida, M.4    Villemin, J.P.5    Auboeuf, D.6    Aitken, S.7    Bertrand, E.8
  • 72
    • 70649088961 scopus 로고    scopus 로고
    • The peculiarities of large intron splicing in animals
    • Shepard S, McCreary M, Fedorov A. 2009. The peculiarities of large intron splicing in animals. PLoS One 4: e7853.
    • (2009) PLoS One , vol.4
    • Shepard, S.1    McCreary, M.2    Fedorov, A.3
  • 74
    • 0035201941 scopus 로고    scopus 로고
    • Structure, mechanism, and evolution of the mRNA capping apparatus
    • Shuman S. 2001. Structure, mechanism, and evolution of the mRNA capping apparatus. Prog Nucleic Acid Res Mol Biol 66: 1-40.
    • (2001) Prog Nucleic Acid Res Mol Biol , vol.66 , pp. 1-40
    • Shuman, S.1
  • 75
    • 70350754211 scopus 로고    scopus 로고
    • Rates of in situ transcription and splicing in large human genes
    • Singh J, Padgett RA. 2009. Rates of in situ transcription and splicing in large human genes. Nat Struct Mol Biol 16: 1128-1133.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 1128-1133
    • Singh, J.1    Padgett, R.A.2
  • 76
    • 78049296915 scopus 로고    scopus 로고
    • Nuclear export of mRNA
    • Stewart M. 2010. Nuclear export of mRNA. Trends Biochem Sci 35: 609-617.
    • (2010) Trends Biochem Sci , vol.35 , pp. 609-617
    • Stewart, M.1
  • 78
    • 0028837312 scopus 로고
    • The human dystrophin gene requires 16 hours to be transcribed and is cotranscriptionally spliced
    • Tennyson CN, Klamut HJ, Worton RG. 1995. The human dystrophin gene requires 16 hours to be transcribed and is cotranscriptionally spliced. Nat Genet 9: 184-190.
    • (1995) Nat Genet , vol.9 , pp. 184-190
    • Tennyson, C.N.1    Klamut, H.J.2    Worton, R.G.3
  • 80
    • 33644525401 scopus 로고    scopus 로고
    • Differential expression of CD45 isoforms is controlled by the combined activity of basal and inducible splicing-regulatory elements in each of the variable exons
    • DOI 10.1074/jbc.M508123200
    • Tong A, Nguyen J, Lynch KW. 2005. Differential expression of CD45 isoforms is controlled by the combined activity of basal and inducible splicing-regulatory elements in each of the variable exons. J Biol Chem 280: 38297-38304. (Pubitemid 43853727)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.46 , pp. 38297-38304
    • Tong, A.1    Nguyen, J.2    Lynch, K.W.3
  • 81
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-Seq
    • Trapnell C, Pachter L, Salzberg SL. 2009. TopHat: Discovering splice junctions with RNA-Seq. Bioinformatics 25: 1105-1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 83
    • 60349104299 scopus 로고    scopus 로고
    • The spliceosome: Design principles of a dynamic RNP machine
    • Wahl MC, Will CL, Luhrmann R. 2009. The spliceosome: Design principles of a dynamic RNP machine. Cell 136: 701-718.
    • (2009) Cell , vol.136 , pp. 701-718
    • Wahl, M.C.1    Will, C.L.2    Luhrmann, R.3
  • 84
    • 0018898480 scopus 로고
    • Order of polyadenylic acid addition and splicing events in early adenovirus mRNA formation
    • Weber J, Blanchard JM, Ginsberg H, Darnell JE Jr. 1980. Order of polyadenylic acid addition and splicing events in early adenovirus mRNA formation. J Virol 33: 286-291. (Pubitemid 10157296)
    • (1980) Journal of Virology , vol.33 , Issue.1 , pp. 286-291
    • Weber, J.1    Blanchard, J.M.2    Ginsberg, H.3    Darnell Jr., J.E.4
  • 85
    • 0029902511 scopus 로고    scopus 로고
    • The intranuclear site of excision of each intron in Balbiani ring 3 pre- mRNA is influenced by the time remaining to transcription termination and different excision efficiencies for the various introns
    • Wetterberg I, Bauren G, Wieslander L. 1996. The intranuclear site of excision of each intron in Balbiani ring 3 pre-mRNA is influenced by the time remaining to transcription termination and different excision efficiencies for the various introns. RNA 2: 641-651. (Pubitemid 26374216)
    • (1996) RNA , vol.2 , Issue.7 , pp. 641-651
    • Wetterberg, I.1    Bauren, G.2    Wieslander, L.3
  • 86
    • 0028090567 scopus 로고
    • Physical isolation of nascent RNA chains transcribed by RNA polymerase II: Evidence for cotranscriptional splicing
    • Wuarin J, Schibler U. 1994. Physical isolation of nascent RNA chains transcribed by RNA polymerase II: Evidence for cotranscriptional splicing. Mol Cell Biol 14: 7219-7225. (Pubitemid 24326386)
    • (1994) Molecular and Cellular Biology , vol.14 , Issue.11 , pp. 7219-7225
    • Wuarin, J.1    Schibler, U.2
  • 87
    • 79960484375 scopus 로고    scopus 로고
    • Gene silencing in X-chromosome inactivation: Advances in understanding facultative heterochromatin formation
    • Wutz A. 2011. Gene silencing in X-chromosome inactivation: Advances in understanding facultative heterochromatin formation. Nat Rev Genet 12: 542-553.
    • (2011) Nat Rev Genet , vol.12 , pp. 542-553
    • Wutz, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.