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Volumn 123, Issue 10, 2010, Pages 1761-1774

The life of an mRNA in space and time

Author keywords

Gene expression; Live cell imaging; mRNA dynamics; Transcription

Indexed keywords

ACTIN; BETA ACTIN; MESSENGER RNA; RNA POLYMERASE II;

EID: 77952408391     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.062638     Document Type: Article
Times cited : (103)

References (61)
  • 1
    • 56849087971 scopus 로고    scopus 로고
    • The dynamics of mammalian P body transport, assembly, and disassembly in vivo
    • Aizer, A., Brody, Y., Ler, L. W., Sonenberg, N., Singer, R. H. and Shav-Tal, Y. (2008). The dynamics of mammalian P body transport, assembly, and disassembly in vivo. Mol. Biol. Cell 19, 4154-4166.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 4154-4166
    • Aizer, A.1    Brody, Y.2    Ler, L.W.3    Sonenberg, N.4    Singer, R.H.5    Shav-Tal, Y.6
  • 2
    • 0028200288 scopus 로고
    • Differential steroid hormone induction of transcription from the Mouse Mammary Tumor Virus promoter
    • DOI 10.1210/me.8.5.568
    • Archer, T. K., Lee, H. L., Cordingley, M. G., Mymryk, J. S., Fragoso, G., Berard, D. S. and Hager, G. L. (1994). Differential steroid hormone induction of transcription from the mouse mammary tumor virus promoter. Mol. Endocrinol. 8, 568-576. (Pubitemid 24174493)
    • (1994) Molecular Endocrinology , vol.8 , Issue.5 , pp. 568-576
    • Archer, T.K.1    Lee, H.-L.2    Cordingley, M.G.3    Mymryk, J.S.4    Fragoso, G.5    Berard, D.S.6    Hager, G.L.7
  • 3
    • 0028214453 scopus 로고
    • Association of poly(A) mRNA with microtubules in cultured neurons
    • DOI 10.1016/0896-6273(94)90213-5
    • Bassell, G. J., Singer, R. H. and Kosik, K. S. (1994). Association of poly(A) mRNA with microtubules in cultured neurons. Neuron 12, 571-582. (Pubitemid 24100888)
    • (1994) Neuron , vol.12 , Issue.3 , pp. 571-582
    • Bassell, G.J.1    Singer, R.H.2    Kosik, K.S.3
  • 4
    • 0033007259 scopus 로고    scopus 로고
    • The travels of mRNAs through all cells large and small
    • Bassell, G. J., Oleynikov, Y. and Singer, R. H. (1999). The travels of mRNAs through all cells large and small. FASEB J. 13, 447-454. (Pubitemid 29115562)
    • (1999) FASEB Journal , vol.13 , Issue.3 , pp. 447-454
    • Bassell, G.J.1    Oleynikov, Y.2    Singer, R.H.3
  • 5
    • 19344378943 scopus 로고    scopus 로고
    • Rules of engagement: Co-transcriptional recruitment of pre-mRNA processing factors
    • Bentley, D. L. (2005). Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors. Curr. Opin. Cell Biol. 17, 251-256.
    • (2005) Curr. Opin. Cell Biol. , vol.17 , pp. 251-256
    • Bentley, D.L.1
  • 7
    • 2342491600 scopus 로고    scopus 로고
    • Photobleaching microscopy reveals the dynamics of mRNA-binding proteins inside live cell nuclei
    • Braga, J., Rino, J. and Carmo-Fonseca, M. (2004). Photobleaching microscopy reveals the dynamics of mRNA-binding proteins inside live cell nuclei. Prog. Mol. Subcell. Biol. 35, 119-134.
    • (2004) Prog. Mol. Subcell. Biol. , vol.35 , pp. 119-134
    • Braga, J.1    Rino, J.2    Carmo-Fonseca, M.3
  • 8
    • 34147151617 scopus 로고    scopus 로고
    • A reaction-diffusion model to study RNA motion by quantitative fluorescence recovery after photobleaching
    • DOI 10.1529/biophysj.106.096693
    • Braga, J., McNally, J. G. and Carmo-Fonseca, M. (2007). A reaction-diffusion model to study RNA motion by quantitative fluorescence recovery after photobleaching. Biophys. J. 92, 2694-2703. (Pubitemid 46557845)
    • (2007) Biophysical Journal , vol.92 , Issue.8 , pp. 2694-2703
    • Braga, J.1    McNally, J.G.2    Carmo-Fonseca, M.3
  • 10
    • 0033642469 scopus 로고    scopus 로고
    • [33] Sensitive and high-resolution detection of RNA in situ
    • Chartrand, P., Bertrand, E., Singer, R. H. and Long, R. M. (2000). Sensitive and high-resolution detection of RNA in situ. Methods Enzymol. 318, 493-506. (Pubitemid 30421668)
    • (2000) Methods in Enzymology , vol.318 , pp. 493-506
    • Chartrand, P.1    Bertrand, E.2    Singer, R.H.3    Long, R.M.4
  • 11
    • 33646591544 scopus 로고    scopus 로고
    • Transcriptional pulsing of a developmental gene
    • Chubb, J. R., Trcek, T., Shenoy, S. M. and Singer, R. H. (2006). Transcriptional pulsing of a developmental gene. Curr. Biol. 16, 1018-1025.
    • (2006) Curr. Biol. , vol.16 , pp. 1018-1025
    • Chubb, J.R.1    Trcek, T.2    Shenoy, S.M.3    Singer, R.H.4
  • 12
    • 13544257399 scopus 로고    scopus 로고
    • How and why does β-actin mRNA target?
    • DOI 10.1042/BC20040063
    • Condeelis, J. and Singer, R. H. (2005). How and why does beta-actin mRNA target? Biol. Cell 97, 97-110. (Pubitemid 40220716)
    • (2005) Biology of the Cell , vol.97 , Issue.1 , pp. 97-110
    • Condeelis, J.1    Singer, R.H.2
  • 14
    • 2242433534 scopus 로고    scopus 로고
    • A kinetic framework for a mammalian RNA polymerase in vivo
    • DOI 10.1126/science.1076164
    • Dundr, M., Hoffmann-Rohrer, U., Hu, Q., Grummt, I., Rothblum, L. I., Phair, R. D. and Misteli, T. (2002). A kinetic framework for a mammalian RNA polymerase in vivo. Science 298, 1623-1626. (Pubitemid 35387201)
    • (2002) Science , vol.298 , Issue.5598 , pp. 1623-1626
    • Dundr, M.1    Hoffmann-Rohrer, U.2    Hu, Q.3    Grummt, I.4    Rothblum, L.I.5    Phair, R.D.6    Misteli, T.7
  • 15
    • 0032562720 scopus 로고    scopus 로고
    • Visualization of single RNA transcripts in situ
    • DOI 10.1126/science.280.5363.585
    • Femino, A. M., Fay, F. S., Fogarty, K. and Singer, R. H. (1998). Visualization of single RNA transcripts in situ. Science 280, 585-590. (Pubitemid 28227761)
    • (1998) Science , vol.280 , Issue.5363 , pp. 585-590
    • Femino, A.M.1    Fay, F.S.2    Fogarty, K.3    Singer, R.H.4
  • 16
    • 0347156907 scopus 로고    scopus 로고
    • Single mRNA molecules demonstrate probabilistic movement in living mammalian cells
    • DOI 10.1016/S0960-9822(02)01436-7, PII S0960982202014367
    • Fusco, D., Accornero, N., Lavoie, B., Shenoy, S. M., Blanchard, J. M., Singer, R. H. and Bertrand, E. (2003). Single mRNA molecules demonstrate probabilistic movement in living mammalian cells. Curr. Biol. 13, 161-167. (Pubitemid 36154346)
    • (2003) Current Biology , vol.13 , Issue.2 , pp. 161-167
    • Fusco, D.1    Accornero, N.2    Lavoie, B.3    Shenoy, S.M.4    Blanchard, J.-M.5    Singer, R.H.6    Bertrand, E.7
  • 18
    • 28944434119 scopus 로고    scopus 로고
    • Real-time kinetics of gene activity in individual bacteria
    • DOI 10.1016/j.cell.2005.09.031, PII S0092867405010378
    • Golding, I., Paulsson, J., Zawilski, S. M. and Cox, E. C. (2005). Real-time kinetics of gene activity in individual bacteria. Cell 123, 1025-1036. (Pubitemid 41785418)
    • (2005) Cell , vol.123 , Issue.6 , pp. 1025-1036
    • Golding, I.1    Paulsson, J.2    Zawilski, S.M.3    Cox, E.C.4
  • 20
    • 0034659241 scopus 로고    scopus 로고
    • RNA polymerase II and the integration of nuclear events
    • Hirose, Y. and Manley, J. L. (2000). RNA polymerase II and the integration of nuclear events. Genes Dev. 14, 1415-1429. (Pubitemid 30421835)
    • (2000) Genes and Development , vol.14 , Issue.12 , pp. 1415-1429
    • Hirose, Y.1    Manley, J.L.2
  • 21
    • 0343307091 scopus 로고    scopus 로고
    • Sorting of actin isoforms in chicken auditory hair cells
    • Hofer, D., Ness, W. and Drenckhahn, D. (1997). Sorting of actin isoforms in chicken auditory hair cells. J. Cell Sci. 110, 765-770. (Pubitemid 27156325)
    • (1997) Journal of Cell Science , vol.110 , Issue.6 , pp. 765-770
    • Hofer, D.1    Ness, W.2    Drenckhahn, D.3
  • 22
    • 33646386142 scopus 로고    scopus 로고
    • Stress fibers are generated by two distinct actin assembly mechanisms in motile cells
    • Hotulainen, P. and Lappalainen, P. (2006). Stress fibers are generated by two distinct actin assembly mechanisms in motile cells. J. Cell Biol. 173, 383-394.
    • (2006) J. Cell Biol. , vol.173 , pp. 383-394
    • Hotulainen, P.1    Lappalainen, P.2
  • 24
    • 0029973080 scopus 로고    scopus 로고
    • Active RNA polymerases are localized within discrete transcription 'factories' in human nuclei
    • Iborra, F. J., Pombo, A., Jackson, D. A. and Cook, P. R. (1996). Active RNA polymerases are localized within discrete transcription 'factories' in human nuclei. J. Cell Sci. 109, 1427-1436.
    • (1996) J. Cell Sci. , vol.109 , pp. 1427-1436
    • Iborra, F.J.1    Pombo, A.2    Jackson, D.A.3    Cook, P.R.4
  • 25
    • 0037376678 scopus 로고    scopus 로고
    • Nuclear choreography: Interpretations from living cells
    • Janicki, S. M. and Spector, D. L. (2003). Nuclear choreography: interpretations from living cells. Curr. Opin. Cell Biol. 15, 149-157.
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 149-157
    • Janicki, S.M.1    Spector, D.L.2
  • 28
    • 11144237626 scopus 로고    scopus 로고
    • The integrin-linked kinase regulates cell morphology and motility in a Rho-associated kinase-dependent manner
    • DOI 10.1074/jbc.M410051200
    • Khyrul, W. A., LaLonde, D. P., Brown, M. C., Levinson, H. and Turner, C. E. (2004). The integrin-linked kinase regulates cell morphology and motility in a rho-associated kinase-dependent manner. J. Biol. Chem. 279, 54131-54139. (Pubitemid 40053149)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.52 , pp. 54131-54139
    • Khyrul, W.A.K.M.1    Lalonde, D.P.2    Brown, M.C.3    Levinson, H.4    Turner, C.E.5
  • 29
    • 33748526877 scopus 로고    scopus 로고
    • Neuronal RNA granules: Movers and makers
    • Kiebler, M. A. and Bassell, G. J. (2006). Neuronal RNA granules: movers and makers. Neuron 51, 685-690.
    • (2006) Neuron , vol.51 , pp. 685-690
    • Kiebler, M.A.1    Bassell, G.J.2
  • 30
    • 0027362779 scopus 로고
    • Isoform-specific 3'-untranslated sequences sort α-cardiac and β- Cytoplasmic actin messenger RNAs to different cytoplasmic compartments
    • Kislauskis, E. H., Li, Z., Singer, R. H. and Taneja, K. L. (1993). Isoform-specific 3′-untranslated sequences sort alpha-cardiac and beta-cytoplasmic actin messenger RNAs to different cytoplasmic compartments. J. Cell Biol. 123, 165-172. (Pubitemid 23284872)
    • (1993) Journal of Cell Biology , vol.123 , Issue.1 , pp. 165-172
    • Kislauskis, E.H.1    Li, Z.2    Singer, R.H.3    Taneja, K.L.4
  • 31
    • 0028027909 scopus 로고
    • Sequences responsible for intracellular localization of β-actin messenger RNA also affect cell phenotype
    • DOI 10.1083/jcb.127.2.441
    • Kislauskis, E. H., Zhu, X. and Singer, R. H. (1994). Sequences responsible for intracellular localization of beta-actin messenger RNA also affect cell phenotype. J. Cell Biol. 127, 441-451. (Pubitemid 24313732)
    • (1994) Journal of Cell Biology , vol.127 , Issue.2 , pp. 441-451
    • Kislauskis, E.H.1    Zhu, X.2    Singer, R.H.3
  • 32
    • 34648816826 scopus 로고    scopus 로고
    • Exporting RNA from the nucleus to the cytoplasm
    • Kohler, A. and Hurt, E. (2007). Exporting RNA from the nucleus to the cytoplasm. Nat. Rev. Mol. Cell Biol. 8, 761-773.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 761-773
    • Kohler, A.1    Hurt, E.2
  • 33
    • 0028169463 scopus 로고
    • Beta-actin mRNA localization is regulated by signal transduction mechanisms
    • Latham, V. M., Jr, Kislauskis, E. H., Singer, R. H. and Ross, A. F. (1994). Beta-actin mRNA localization is regulated by signal transduction mechanisms. J. Cell Biol. 126, 1211-1219. (Pubitemid 2131431)
    • (1994) Journal of Cell Biology , vol.126 , Issue.5 , pp. 1211-1219
    • Latham Jnr, V.M.1    Kislauskis, E.H.2    Singer, R.H.3    Ross, A.F.4
  • 34
    • 0022497718 scopus 로고
    • Intracellular localization of messenger RNAs for cytoskeletal proteins
    • Lawrence, J. B. and Singer, R. H. (1986). Intracellular localization of messenger RNAs for cytoskeletal proteins. Cell 45, 407-415. (Pubitemid 16014990)
    • (1986) Cell , vol.45 , Issue.3 , pp. 407-415
    • Lawrence, J.B.1    Singer, R.H.2
  • 35
    • 0037041395 scopus 로고    scopus 로고
    • An extensive network of coupling among gene expression machines
    • DOI 10.1038/416499a
    • Maniatis, T. and Reed, R. (2002). An extensive network of coupling among gene expression machines. Nature 416, 499-506. (Pubitemid 34288845)
    • (2002) Nature , vol.416 , Issue.6880 , pp. 499-506
    • Maniatis, T.1    Reed, R.2
  • 36
    • 24644502657 scopus 로고    scopus 로고
    • From birth to death: The complex lives of eukaryotic mRNAs
    • Moore, M. J. (2005). From birth to death: the complex lives of eukaryotic mRNAs. Science 309, 1514-1518.
    • (2005) Science , vol.309 , pp. 1514-1518
    • Moore, M.J.1
  • 37
    • 60149110358 scopus 로고    scopus 로고
    • Pre-mRNA processing reaches back to transcription and ahead to translation
    • Moore, M. J. and Proudfoot, N. J. (2009). Pre-mRNA processing reaches back to transcription and ahead to translation. Cell 136, 688-700.
    • (2009) Cell , vol.136 , pp. 688-700
    • Moore, M.J.1    Proudfoot, N.J.2
  • 38
    • 0035833262 scopus 로고    scopus 로고
    • Large-scale chromatin decondensation and recondensation regulated by transcription from a natural promoter
    • DOI 10.1083/jcb.200011069
    • Muller, W. G., Walker, D., Hager, G. L. and McNally, J. G. (2001). Large-scale chromatin decondensation and recondensation regulated by transcription from a natural promoter. J. Cell Biol. 154, 33-48. (Pubitemid 34289276)
    • (2001) Journal of Cell Biology , vol.154 , Issue.1 , pp. 33-48
    • Muller, W.G.1    Walker, D.2    Hager, G.L.3    McNally, J.G.4
  • 39
    • 0037107547 scopus 로고    scopus 로고
    • On the importance of being co-transcriptional
    • Neugebauer, K. M. (2002). On the importance of being co-transcriptional. J. Cell Sci. 115, 3865-3871.
    • (2002) J. Cell Sci. , vol.115 , pp. 3865-3871
    • Neugebauer, K.M.1
  • 40
    • 0034611785 scopus 로고    scopus 로고
    • High mobility of proteins in the mammalian cell nucleus
    • Phair, R. D. and Misteli, T. (2000). High mobility of proteins in the mammalian cell nucleus. Nature 404, 604-609.
    • (2000) Nature , vol.404 , pp. 604-609
    • Phair, R.D.1    Misteli, T.2
  • 41
    • 0033909431 scopus 로고    scopus 로고
    • Review: Movement of mRNA from transcription site to nuclear pores
    • Politz, J. C. and Pederson, T. (2000). Review: movement of mRNA from transcription site to nuclear pores. J. Struct. Biol. 129, 252-257.
    • (2000) J. Struct. Biol. , vol.129 , pp. 252-257
    • Politz, J.C.1    Pederson, T.2
  • 44
    • 0030956033 scopus 로고    scopus 로고
    • Single-particle tracking: Applications to membrane dynamics
    • Saxton, M. J. and Jacobson, K. (1997). Single-particle tracking: applications to membrane dynamics. Annu. Rev. Biophys. Biomol. Struct. 26, 373-399.
    • (1997) Annu. Rev. Biophys. Biomol. Struct. , vol.26 , pp. 373-399
    • Saxton, M.J.1    Jacobson, K.2
  • 45
    • 27144552892 scopus 로고    scopus 로고
    • RNA localization
    • Shav-Tal, Y. and Singer, R. H. (2005). RNA localization. J. Cell Sci. 118, 4077-4081.
    • (2005) J. Cell Sci. , vol.118 , pp. 4077-4081
    • Shav-Tal, Y.1    Singer, R.H.2
  • 46
    • 77952397890 scopus 로고    scopus 로고
    • Single-molecule dynamics of nuclear mRNA
    • Shav-Tal, Y. and Gruenbaum, Y. (2009). Single-molecule dynamics of nuclear mRNA. F1000 Biology Reports 1, 29-32.
    • (2009) F1000 Biology Reports , vol.1 , pp. 29-32
    • Shav-Tal, Y.1    Gruenbaum, Y.2
  • 49
    • 33747615285 scopus 로고    scopus 로고
    • Gene expression within a dynamic nuclear landscape
    • DOI 10.1038/sj.emboj.7601226, PII 7601226
    • Shav-Tal, Y., Darzacq, X. and Singer, R. H. (2006). Gene expression within a dynamic nuclear landscape. EMBO J. 25, 3469-3479. (Pubitemid 44264858)
    • (2006) EMBO Journal , vol.25 , Issue.15 , pp. 3469-3479
    • Shav-Tal, Y.1    Darzacq, X.2    Singer, R.H.3
  • 50
    • 0035912805 scopus 로고    scopus 로고
    • The physiological significance of beta-actin mRNA localization in determining cell polarity and directional motility
    • Shestakova, E. A., Singer, R. H. and Condeelis, J. (2001). The physiological significance of beta-actin mRNA localization in determining cell polarity and directional motility. Proc. Natl. Acad. Sci. USA 98, 7045-7050.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7045-7050
    • Shestakova, E.A.1    Singer, R.H.2    Condeelis, J.3
  • 51
    • 70350754211 scopus 로고    scopus 로고
    • Rates of in situ transcription and splicing in large human genes
    • Singh, J. and Padgett, R. A. (2009). Rates of in situ transcription and splicing in large human genes. Nat. Struct. Mol. Biol. 16, 1128-1133.
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 1128-1133
    • Singh, J.1    Padgett, R.A.2
  • 52
    • 2942690158 scopus 로고    scopus 로고
    • Analysis of binding reactions by fluorescence recovery after photobleaching
    • DOI 10.1529/biophysj.103.026765
    • Sprague, B. L., Pego, R. L., Stavreva, D. A. and McNally, J. G. (2004). Analysis of binding reactions by fluorescence recovery after photobleaching. Biophys. J. 86, 3473-3495. (Pubitemid 38780231)
    • (2004) Biophysical Journal , vol.86 , Issue.6 , pp. 3473-3495
    • Sprague, B.L.1    Pego, R.L.2    Stavreva, D.A.3    McNally, J.G.4
  • 53
    • 0026010429 scopus 로고
    • Requirement of microfilaments in sorting of actin messenger RNA
    • Sundell, C. L. and Singer, R. H. (1991). Requirement of microfilaments in sorting of actin messenger RNA. Science 253, 1275-1277.
    • (1991) Science , vol.253 , pp. 1275-1277
    • Sundell, C.L.1    Singer, R.H.2
  • 54
    • 67649766870 scopus 로고    scopus 로고
    • Transcription factories: Gene expression in unions?
    • Sutherland, H. and Bickmore, W. A. (2009). Transcription factories: gene expression in unions? Nat. Rev. Genet. 10, 457-466.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 457-466
    • Sutherland, H.1    Bickmore, W.A.2
  • 56
    • 0033612538 scopus 로고    scopus 로고
    • Large-scale chromatin unfolding and remodeling induced by VP16 acidic activation domain
    • DOI 10.1083/jcb.145.7.1341
    • Tumbar, T., Sudlow, G. and Belmont, A. S. (1999). Large-scale chromatin unfolding and remodeling induced by VP16 acidic activation domain. J. Cell Biol. 145, 1341-1354. (Pubitemid 29309994)
    • (1999) Journal of Cell Biology , vol.145 , Issue.7 , pp. 1341-1354
    • Tumbar, T.1    Sudlow, G.2    Belmont, A.S.3
  • 57
    • 10044298658 scopus 로고    scopus 로고
    • Imaging native β-actin mRNA in motile fibroblasts
    • DOI 10.1529/biophysj.104.045153
    • Tyagi, S. and Alsmadi, O. (2004). Imaging native beta-actin mRNA in motile fibroblasts. Biophys. J. 87, 4153-4162. (Pubitemid 39602919)
    • (2004) Biophysical Journal , vol.87 , Issue.6 , pp. 4153-4162
    • Tyagi, S.1    Alsmadi, O.2
  • 61
    • 13544262618 scopus 로고    scopus 로고
    • VICKZ proteins: A multi-talented family of regulatory RNA-binding proteins
    • Yisraeli, J. K. (2005). VICKZ proteins: a multi-talented family of regulatory RNA-binding proteins. Biol. Cell 97, 87-96.
    • (2005) Biol. Cell , vol.97 , pp. 87-96
    • Yisraeli, J.K.1


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