PGC-1β mediates adaptive chemoresistance associated with mitochondrial DNA mutations

Oncogene

Volumn 32, Issue 20, 2013, Pages 2592-2600

  Yao, Z ^a   Jones, A W E ^a,h   Fassone, E ^b,c   Sweeney, M G ^d   Lebiedzinska, M ^e   Suski, J M ^e   Wieckowski, M R ^e   Tajeddine, N ^f   Hargreaves, I P ^g   Yasukawa, T ^h   Tufo, G ⁱ   Brenner, C ⁱ   Kroemer, G ^f,j,k,l   Rahman, S ^b   Szabadkai, G ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF MILAN   (Italy)

^d NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^e NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^f INSTITUT GUSTAVE ROUSSY   (France)

^g UNIVERSITY COLLEGE LONDON   (United Kingdom)

^h UNIVERSITY COLLEGE LONDON   (United Kingdom)

ⁱ UNIVERSITÉ PARIS SACLAY   (France)

^j CENTRE DE RECHERCHE DES CORDELIERS   (France)

^k HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^l UNIVERSITÉ PARIS DESCARTES   (France)

more..

Author keywords

CDDP; Chemoresistance; Complex I; Mitochondrial biogenesis; Mitochondrial DNA; PGC 1

Indexed keywords

CISPLATIN; MITOCHONDRIAL DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

APOPTOSIS; ARTICLE; BIOGENESIS; CONTROLLED STUDY; GENOTOXICITY; LUNG NON SMALL CELL CANCER; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RESPIRATORY CHAIN; SENSITIVITY ANALYSIS; UPREGULATION;

ADAPTATION, PHYSIOLOGICAL; CARCINOMA, NON-SMALL-CELL LUNG; CARRIER PROTEINS; CELL LINE, TUMOR; CISPLATIN; DNA, MITOCHONDRIAL; DRUG RESISTANCE, NEOPLASM; HEAT-SHOCK PROTEINS; HUMANS; LUNG NEOPLASMS; MUTATION; NADH DEHYDROGENASE; TRANSCRIPTION FACTORS;

EID: 84878015925     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.259     Document Type: Article

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