메뉴 건너뛰기




Volumn 27, Issue 6, 2013, Pages 864-878

Minireview: The diverse roles of nuclear receptors in the regulation of embryonic stem cell pluripotency

Author keywords

GCNF; Nuclear receptors; NURSA molecule pages

Indexed keywords

CELL NUCLEUS RECEPTOR; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 1; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 2; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 3; ESTROGEN RELATED RECEPTOR BETA; LIVER RECEPTOR HOMOLOG 1; MICRORNA; MICRORNA 134; MICRORNA 296; MICRORNA 470; NUCLEAR RECEPTOR DAX 1; OCTAMER TRANSCRIPTION FACTOR 4; RETINOIC ACID RECEPTOR; RETINOID; RETINOID X RECEPTOR ALPHA; RETINOID X RECEPTOR BETA; RETINOID X RECEPTOR GAMMA; STEROID RECEPTOR; STEROIDOGENIC FACTOR 1; TESTICULAR ORPHAN RECEPTOR 2; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

EID: 84877889534     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2012-1383     Document Type: Review
Times cited : (13)

References (155)
  • 2
    • 34447607512 scopus 로고
    • Congenitales, quergestreiftes muskelsarkom der nieren
    • Cohnheim V. Congenitales, quergestreiftes muskelsarkom der nieren. Virchows Arch Pathol Anat Physiol Klin Med. 1875: 65: 64-69.
    • (1875) Virchows Arch Pathol Anat Physiol Klin Med , vol.65 , pp. 64-69
    • Cohnheim, V.1
  • 3
    • 84877911921 scopus 로고
    • Experiments on the orgin of tumors
    • Experiments on the orgin of tumors. Br Med J. 1881;2;636-637.
    • (1881) Br Med J , vol.2 , pp. 636-637
  • 4
    • 0014782790 scopus 로고
    • Developmental potentialities of clonal in vitro cultures of mouse testicular teratoma
    • Kahan BW, Ephrussi B. Developmental potentialities of clonal in vitro cultures of mouse testicular teratoma. J Nat Cancer Inst. 1970;44:1015-1036.
    • (1970) J Nat Cancer Inst , vol.44 , pp. 1015-1036
    • Kahan, B.W.1    Ephrussi, B.2
  • 5
    • 0014782736 scopus 로고
    • In vitro growth and differentiation of clonal populations of multipotential mouse cells derived from a transplantable testicular teratoma
    • Rosenthal MD, Wishnow RW, Sato GH. In vitro growth and differentiation of clonal populations of multipotential mouse cells derived from a transplantable testicular teratoma J Nat Cancer Inst. 1970;44:1001-1014.
    • (1970) J Nat Cancer Inst , vol.44 , pp. 1001-1014
    • Rosenthal, M.D.1    Wishnow, R.W.2    Sato, G.H.3
  • 6
    • 0015379899 scopus 로고
    • The isolation and properties of a clonal tissue culture strain of pluripotent mouse teratoma cells
    • Evans MJ. The isolation and properties of a clonal tissue culture strain of pluripotent mouse teratoma cells. J Embryol Exp Morph. 1972;28:163-176.
    • (1972) J Embryol Exp Morph , vol.28 , pp. 163-176
    • Evans, M.J.1
  • 7
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature. 1981;292:154-156.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 8
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA. 1981;78(12):7634-8.
    • (1981) Proc Natl Acad Sci USA , vol.78 , Issue.12 , pp. 7634-7638
    • Martin, G.R.1
  • 9
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science. 1998; 282: 1145-1147.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 10
    • 0028726028 scopus 로고
    • Embryonic germ cell lines and their derivation from mouse primordial germ cells
    • Labosky PA, Barlow DP, Hogan BL. Embryonic germ cell lines and their derivation from mouse primordial germ cells. Ciba Found Symp. 1994;182:157-168.
    • (1994) Ciba Found Symp , vol.182 , pp. 157-168
    • Labosky, P.A.1    Barlow, D.P.2    Hogan, B.L.3
  • 11
    • 0027942245 scopus 로고
    • Mouse embryonic germ (EG) cell lines: Transmission through the germline and differences in the methylation imprint of insulin-like growth factor 2 receptor (Igf2r) gene compared with embryonic stem (ES) cell lines
    • Labosky PA, Barlow DP, Hogan BL. Mouse embryonic germ (EG) cell lines: transmission through the germline and differences in the methylation imprint of insulin-like growth factor 2 receptor (Igf2r) gene compared with embryonic stem (ES) cell lines. Development. 1994;120(11):3197-3204.
    • (1994) Development , vol.120 , Issue.11 , pp. 3197-3204
    • Labosky, P.A.1    Barlow, D.P.2    Hogan, B.L.3
  • 12
    • 34447527158 scopus 로고    scopus 로고
    • Derivation of pluripotent epiblast stem cells from mammalian embryos
    • Brons IG, Smithers LE, Trotter MW, et al. Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature. 2007; 448:191-195.
    • (2007) Nature , vol.448 , pp. 191-195
    • Brons, I.G.1    Smithers, L.E.2    Trotter, M.W.3
  • 13
    • 34447528757 scopus 로고    scopus 로고
    • New cell lines from mouse epiblast share defining features with human embryonic stem cells
    • Tesar PJ, Chenoweth JG, Brook FA, et al. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature. 2007;448:196-199.
    • (2007) Nature , vol.448 , pp. 196-199
    • Tesar, P.J.1    Chenoweth, J.G.2    Brook, F.A.3
  • 14
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 15
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007;131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 16
    • 39149130361 scopus 로고    scopus 로고
    • Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
    • Jaenisch R, Young R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell. 2008;132:567-582.
    • (2008) Cell , vol.132 , pp. 567-582
    • Jaenisch, R.1    Young, R.2
  • 17
    • 34249909232 scopus 로고    scopus 로고
    • Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
    • Maherali N, Sridharan R, Xie W, et al. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 2007;1:55-70.
    • (2007) Cell Stem Cell , vol.1 , pp. 55-70
    • Maherali, N.1    Sridharan, R.2    Xie, W.3
  • 18
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF, et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell. 2005;122:947-956.
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3
  • 19
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh YH, Wu Q, Chew JL, et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet. 2006;38:431-440.
    • (2006) Nat Genet , vol.38 , pp. 431-440
    • Loh, Y.H.1    Wu, Q.2    Chew, J.L.3
  • 20
    • 34249876564 scopus 로고    scopus 로고
    • Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
    • Masui S, Nakatake K, Toyooka Y, et al. Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat Cell Biol. 2007;9:625-635.
    • (2007) Nat Cell Biol , vol.9 , pp. 625-635
    • Masui, S.1    Nakatake, K.2    Toyooka, Y.3
  • 21
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee TI, Jenner RG, Boyer LA, et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 2006; 125:301-313.
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3
  • 22
    • 33646882068 scopus 로고    scopus 로고
    • Polycomb complexes repress developmental regulators in murine embryonic stem cells
    • Boyer LA, Plath K, Zeitlinger J, et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature. 2006;441:349-353.
    • (2006) Nature , vol.441 , pp. 349-353
    • Boyer, L.A.1    Plath, K.2    Zeitlinger, J.3
  • 23
    • 0032582513 scopus 로고    scopus 로고
    • Formation of pluripotent stem cells in the mammalian embryo dependes on the POU transcription factor Oct4
    • Nichols J, Zevnik B, Anastassiadis K, et al. Formation of pluripotent stem cells in the mammalian embryo dependes on the POU transcription factor Oct4. Cell. 1998;95:379-391.
    • (1998) Cell , vol.95 , pp. 379-391
    • Nichols, J.1    Zevnik, B.2    Anastassiadis, K.3
  • 24
    • 0037227099 scopus 로고    scopus 로고
    • Multipotent cell lineages in early mouse development depend on SOX2 function
    • Avilion AA, Nicolis SK, Pevny LH, et al. Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev. 2003;17:126-140.
    • (2003) Genes Dev , vol.17 , pp. 126-140
    • Avilion, A.A.1    Nicolis, S.K.2    Pevny, L.H.3
  • 25
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein Nanog is required for maintenance of pluripotency in the mouse epiblast and ES cells
    • Mitsui K, Tokuzawa Y, Itoh H, et al. The homeoprotein Nanog is required for maintenance of pluripotency in the mouse epiblast and ES cells. Cell. 113:631-642.
    • Cell , vol.113 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3
  • 26
    • 37549002155 scopus 로고    scopus 로고
    • Nanog safeguards pluripotency and mediates germline development
    • Chambers I, Silva J, Colby D, et al. Nanog safeguards pluripotency and mediates germline development. Nature 2007;450:1230-1234.
    • (2007) Nature , vol.450 , pp. 1230-1234
    • Chambers, I.1    Silva, J.2    Colby, D.3
  • 27
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • Chambers I, Colby D, Roberson M, et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell. 2003;113:643-655.
    • (2003) Cell , vol.113 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Roberson, M.3
  • 28
    • 29444461024 scopus 로고    scopus 로고
    • Changes in attitude, changes in latitude: Nuclear receptors remodeling chromatin to regulate transcription
    • Chen J, Karimi H, Archer T. Changes in attitude, changes in latitude: nuclear receptors remodeling chromatin to regulate transcription. Mol Endocrinol. 2006;20(1):1-13.
    • (2006) Mol Endocrinol , vol.20 , Issue.1 , pp. 1-13
    • Chen, J.1    Karimi, H.2    Archer, T.3
  • 29
    • 34547731515 scopus 로고    scopus 로고
    • Nuclear receptor coregulators and human disease
    • Lonard DM, Lanz RB, OMalley BW. Nuclear receptor coregulators and human disease. Endocr Rev. 2007;28(5):575-87.
    • (2007) Endocr Rev , vol.28 , Issue.5 , pp. 575-587
    • Lonard, D.M.1    Lanz, R.B.2    Omalley, B.W.3
  • 31
    • 0012473279 scopus 로고
    • The nuclear receptor superfamily: The second decade
    • Mangelsdorf DJ, Thummel C, Beato M, et al. The nuclear receptor superfamily: the second decade. Cell. 1995;83:835-839.
    • (1995) Cell , vol.83 , pp. 835-839
    • Mangelsdorf, D.J.1    Thummel, C.2    Beato, M.3
  • 32
    • 0035498850 scopus 로고    scopus 로고
    • The end of the beginning for pluripotent stem cells
    • Donovan PJ, Gearhart J. The end of the beginning for pluripotent stem cells. Nature. 2001;414:92-97.
    • (2001) Nature , vol.414 , pp. 92-97
    • Donovan, P.J.1    Gearhart, J.2
  • 33
    • 0016489816 scopus 로고
    • The differentiation of clonal lines of teratocarcinoma cells: Formation of embryoid bodies in vitro
    • Martin GR, Evans MJ. The differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro. Proc Nat Acad Sci U S A. 1975;72:1441-1445.
    • (1975) Proc Nat Acad Sci U S A , vol.72 , pp. 1441-1445
    • Martin, G.R.1    Evans, M.J.2
  • 34
    • 0018165501 scopus 로고
    • The induction of differentiation in teratocarcinoma stem cells by retinoic acid
    • Strickland S, Mahdavi V. The induction of differentiation in teratocarcinoma stem cells by retinoic acid. Cell. 1978;15:393-403.
    • (1978) Cell , vol.15 , pp. 393-403
    • Strickland, S.1    Mahdavi, V.2
  • 35
    • 84989611379 scopus 로고
    • Tissue changes following deprivation of fat-soluble A vitamin
    • Wolbach SB, Howe PR. Tissue changes following deprivation of fat-soluble A vitamin. J Exp Med. 1925;42:753-777.
    • (1925) J Exp Med , vol.42 , pp. 753-777
    • Wolbach, S.B.1    Howe, P.R.2
  • 36
    • 0018070147 scopus 로고
    • Plasminogen activator in chick embryo fibroblasts: Induction of enzyme synthesis by retinoic acid; synergism with viral transformation and phorbol ester
    • Wilson EL, Reich E. Plasminogen activator in chick embryo fibroblasts: induction of enzyme synthesis by retinoic acid; synergism with viral transformation and phorbol ester. Cell. 1978;15:385-392.
    • (1978) Cell , vol.15 , pp. 385-392
    • Wilson, E.L.1    Reich, E.2
  • 37
    • 76549257742 scopus 로고
    • Effects of locally applied vitamin A and estrogen on rat epidermis
    • Sabella JD, Bern HA, Kahn RH. Effects of locally applied vitamin A and estrogen on rat epidermis. Proc Soc Exp Biol Med. 1951; 76:499-503.
    • (1951) Proc Soc Exp Biol Med , vol.76 , pp. 499-503
    • Sabella, J.D.1    Bern, H.A.2    Kahn, R.H.3
  • 38
    • 0016158553 scopus 로고
    • Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro
    • Yuspa SH, Harris CC. Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro. Exp Cell Res. 1974;86: 95-105.
    • (1974) Exp Cell Res , vol.86 , pp. 95-105
    • Yuspa, S.H.1    Harris, C.C.2
  • 39
    • 0018948184 scopus 로고
    • Hormonal induction of differentiation in teratocarcinoma stem cells: Generation of parietal endoderm by retinoic acid and dibutyryl cAMP
    • Strickland S, Smith, KK., Marotti KR. Hormonal induction of differentiation in teratocarcinoma stem cells: generation of parietal endoderm by retinoic acid and dibutyryl cAMP. Cell. 1980; 21:347-355.
    • (1980) Cell , vol.21 , pp. 347-355
    • Strickland, S.1    Smith, K.K.2    Marotti, K.R.3
  • 40
    • 0018713123 scopus 로고
    • The induction of antigenic changes in a teratocarcinoma stem cell line (F9) by retinoic acid
    • Solter D, Shevinsky L, Knowles BB, Strickland S. The induction of antigenic changes in a teratocarcinoma stem cell line (F9) by retinoic acid. Dev Biol. 1979;70:515-521.
    • (1979) Dev Biol , vol.70 , pp. 515-521
    • Solter, D.1    Shevinsky, L.2    Knowles, B.B.3    Strickland, S.4
  • 41
    • 0025339242 scopus 로고
    • Characteristics of embryonic stem cell differentiation: A comparison with two embryonal carcinoma cell lines
    • Mummery CL, Feyen A, Freund E, Shen S. Characteristics of embryonic stem cell differentiation: a comparison with two embryonal carcinoma cell lines. Cell Differ Dev. 1990;30:195-206.
    • (1990) Cell Differ Dev , vol.30 , pp. 195-206
    • Mummery, C.L.1    Feyen, A.2    Freund, E.3    Shen, S.4
  • 42
    • 0029865895 scopus 로고    scopus 로고
    • Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells
    • Yeom Y, Fuhrmann G, Ovitt CE, et al. Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells. Development 1996;122(3):881-94.
    • (1996) Development , vol.122 , Issue.3 , pp. 881-894
    • Yeom, Y.1    Fuhrmann, G.2    Ovitt, C.E.3
  • 43
    • 21744444920 scopus 로고    scopus 로고
    • Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells
    • Chew JL, Loh YH, Zhang W, et al. Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells. Mol Cell Biol. 2005;25:6031-6046.
    • (2005) Mol Cell Biol , vol.25 , pp. 6031-6046
    • Chew, J.L.1    Loh, Y.H.2    Zhang, W.3
  • 44
    • 14044275706 scopus 로고    scopus 로고
    • Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells
    • Okumura-Nakanishi S, Saito M, Niwa H, et al. Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells. J Biol Chem. 2005; 240:5307-5317.
    • (2005) J Biol Chem , vol.240 , pp. 5307-5317
    • Okumura-Nakanishi, S.1    Saito, M.2    Niwa, H.3
  • 45
    • 0025812646 scopus 로고
    • The oct3 gene, a gene for an embryonic transcription factor, is controlled by a retinoic acid repressible enhancer
    • Okazawa H, Okamoto K, Ishino F, et al. The oct3 gene, a gene for an embryonic transcription factor, is controlled by a retinoic acid repressible enhancer. EMBO J. 1991;10(10):2997-3005.
    • (1991) EMBO J , vol.10 , Issue.10 , pp. 2997-3005
    • Okazawa, H.1    Okamoto, K.2    Ishino, F.3
  • 46
    • 0024337858 scopus 로고
    • Determinants of target gene specificity for steroid/thyroid hormone receptors
    • Umesono K, Evans RM. Determinants of target gene specificity for steroid/thyroid hormone receptors. Cell. 1989;57:1139-1146.
    • (1989) Cell , vol.57 , pp. 1139-1146
    • Umesono, K.1    Evans, R.M.2
  • 47
    • 0025812291 scopus 로고
    • Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors
    • Umesono K, Murakami KK, Thompson CC, Evans RM. Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors. Cell. 1991;65:1255-1266.
    • (1991) Cell , vol.65 , pp. 1255-1266
    • Umesono, K.1    Murakami, K.K.2    Thompson, C.C.3    Evans, R.M.4
  • 48
    • 0028014396 scopus 로고
    • Retinoic acid represses Oct-3/4 gene expression through several retinoic acid-responsive elements located in the promoter-enhancer region
    • Pikarsky E, Sharir H, Ben-Shushan E, et al. Retinoic acid represses Oct-3/4 gene expression through several retinoic acid-responsive elements located in the promoter-enhancer region. Mol Cell Biol. 1994;14(2):1026-38.
    • (1994) Mol Cell Biol , vol.14 , Issue.2 , pp. 1026-1038
    • Pikarsky, E.1    Sharir, H.2    Ben-Shushan, E.3
  • 49
    • 0028140270 scopus 로고
    • Characterization of a negative retinoic acid response element in the murine Oct4 promoter
    • Schoorlemmer J, van Puijenbroek A, van den Eijnden M, et al. Characterization of a negative retinoic acid response element in the murine Oct4 promoter. Mol Cell Biol. 1994;14(2):1122-36.
    • (1994) Mol Cell Biol , vol.14 , Issue.2 , pp. 1122-1136
    • Schoorlemmer, J.1    van Puijenbroek, A.2    van den Eijnden, M.3
  • 50
    • 23444450223 scopus 로고
    • Regulation of Oct-4 gene by nuclear receptors
    • Sylvester I, Schöler H. Regulation of Oct-4 gene by nuclear receptors. Nucleic Acids Res. 1994;22(6):901-11.
    • (1994) Nucleic Acids Res , vol.22 , Issue.6 , pp. 901-911
    • Sylvester, I.1    Schöler, H.2
  • 51
    • 0028821102 scopus 로고
    • A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:Retinoid X receptor heterodimers regulates Oct- 3/4 expresssion in embryonal carcinoma cells
    • Ben-Shushan E, Sharir H, Pikarsky E, Bergman Y. A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct- 3/4 expresssion in embryonal carcinoma cells. Mol Cell Biol. 1995;15(2):1034-48.
    • (1995) Mol Cell Biol , vol.15 , Issue.2 , pp. 1034-1048
    • Ben-Shushan, E.1    Sharir, H.2    Pikarsky, E.3    Bergman, Y.4
  • 52
    • 0034054503 scopus 로고    scopus 로고
    • Synergy of SF1 and RAR in activation of Oct-3/4 promoter
    • Barnea E, Bergman Y. Synergy of SF1 and RAR in activation of Oct-3/4 promoter. J Biol Chem. 2000;275(9):6608-19.
    • (2000) J Biol Chem , vol.275 , Issue.9 , pp. 6608-6619
    • Barnea, E.1    Bergman, Y.2
  • 53
    • 20244381404 scopus 로고    scopus 로고
    • Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development
    • Gu P, Goodwin B, Chung AC, et al. Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development. Mol Cell Biol. 2005;25(9): 3492-505.
    • (2005) Mol Cell Biol , vol.25 , Issue.9 , pp. 3492-3505
    • Gu, P.1    Goodwin, B.2    Chung, A.C.3
  • 54
    • 25444473355 scopus 로고    scopus 로고
    • Orphan nuclear receptor GCNF is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation
    • Gu P, Le Menuet D, Chung AC, et al. Orphan nuclear receptor GCNF is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation. Mol Cell Biol. 2005;25(19):8507-19.
    • (2005) Mol Cell Biol , vol.25 , Issue.19 , pp. 8507-8519
    • Gu, P.1    Le Menuet, D.2    Chung, A.C.3
  • 55
    • 7844233314 scopus 로고    scopus 로고
    • The molecular biology of Oct-4 in the early mouse embryo
    • Ovitt CE, Schöler HR. The molecular biology of Oct-4 in the early mouse embryo. Mol Hum Reprod. 1998;4(11):1021-31.
    • (1998) Mol Hum Reprod , vol.4 , Issue.11 , pp. 1021-1031
    • Ovitt, C.E.1    Schöler, H.R.2
  • 56
    • 68249087053 scopus 로고    scopus 로고
    • Variation in the safety of induced pluripotent stem cell lines
    • Miura K, Okada Y, Aoi T, et al. Variation in the safety of induced pluripotent stem cell lines. Nat Biotechnol. 2009;27(8):743-5.
    • (2009) Nat Biotechnol , vol.27 , Issue.8 , pp. 743-745
    • Miura, K.1    Okada, Y.2    Aoi, T.3
  • 57
    • 77952425747 scopus 로고    scopus 로고
    • Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
    • Stadtfeld M, Apostolou E, Akutsu H, et al. Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature. 2010;465:175-181.
    • (2010) Nature , vol.465 , pp. 175-181
    • Stadtfeld, M.1    Apostolou, E.2    Akutsu, H.3
  • 58
    • 33751505837 scopus 로고    scopus 로고
    • International union of pharmacology. LX. Retinoic acid receptors
    • Germain P, Chambon P, Eichele G, et al. International union of pharmacology. LX. Retinoic acid receptors. Pharmacol Rev. 2006;58(4):760-772.
    • (2006) Pharmacol Rev , vol.58 , Issue.4 , pp. 760-772
    • Germain, P.1    Chambon, P.2    Eichele, G.3
  • 59
    • 0033582236 scopus 로고    scopus 로고
    • Retinoid X receptors are essential for early mouse development and placentogenesis
    • Wendling O, Chambon P, Mark M. Retinoid X receptors are essential for early mouse development and placentogenesis. Proc Natl Acad Sci USA. 1999;96:547-551.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 547-551
    • Wendling, O.1    Chambon, P.2    Mark, M.3
  • 60
  • 61
    • 0030601129 scopus 로고    scopus 로고
    • Retinoic acid promotes neural and represses mesodermal gene expression in mouse embryonic stem cells in culture
    • Bain G, Ray WJ, Yao M, Gottlieb DI. Retinoic acid promotes neural and represses mesodermal gene expression in mouse embryonic stem cells in culture. Biochem Biophys Res Commun. 1996;223(3):691-694.
    • (1996) Biochem Biophys Res Commun , vol.223 , Issue.3 , pp. 691-694
    • Bain, G.1    Ray, W.J.2    Yao, M.3    Gottlieb, D.I.4
  • 62
    • 63349094725 scopus 로고    scopus 로고
    • Regulation of mouse embryonic stem cell neural differentiation by retinoic acid
    • Kim M, Habbiba A, Doherty JM, et al. Regulation of mouse embryonic stem cell neural differentiation by retinoic acid. Dev Biol. 2009;328:456-471.
    • (2009) Dev Biol , vol.328 , pp. 456-471
    • Kim, M.1    Habbiba, A.2    Doherty, J.M.3
  • 63
    • 38349064711 scopus 로고    scopus 로고
    • MicroRNA-134 modulates the differentiation of mouse embryonic stem cells where is causes posttranscriptional attenuation of Nanog and LRH-1
    • Tay YM, Tam WL, Ang YS, et al. MicroRNA-134 modulates the differentiation of mouse embryonic stem cells where is causes posttranscriptional attenuation of Nanog and LRH-1. Stem Cells. 2008;26(1):17-29.
    • (2008) Stem Cells , vol.26 , Issue.1 , pp. 17-29
    • Tay, Y.M.1    Tam, W.L.2    Ang, Y.S.3
  • 64
    • 54549108798 scopus 로고    scopus 로고
    • MicroRNAs to Nanog, Oct4, and Sox2 coding regions modulate embryonic stem cell differentiation
    • Tay Y, Zhang J, Thomson AM, et al. MicroRNAs to Nanog, Oct4, and Sox2 coding regions modulate embryonic stem cell differentiation. Nature. 2008;455:1124-1128.
    • (2008) Nature , vol.455 , pp. 1124-1128
    • Tay, Y.1    Zhang, J.2    Thomson, A.M.3
  • 65
    • 73549101275 scopus 로고    scopus 로고
    • Cell-specific interaction of retinoic acid receptors with target genes in mouse embryonic fibroblasts and embryonic stem cells
    • Delacroix L, Moutier E, Altobelli G, et al. Cell-specific interaction of retinoic acid receptors with target genes in mouse embryonic fibroblasts and embryonic stem cells. Mol Cell Biol. 2010;30(1): 231-244.
    • (2010) Mol Cell Biol , vol.30 , Issue.1 , pp. 231-244
    • Delacroix, L.1    Moutier, E.2    Altobelli, G.3
  • 66
    • 0036468157 scopus 로고    scopus 로고
    • Sonic hedgehog in CNS development: One signal, multiple outputs
    • Marti E, Bovolenta P. Sonic hedgehog in CNS development: one signal, multiple outputs. Trends Neurosci. 2002;25(2):89-96.
    • (2002) Trends Neurosci , vol.25 , Issue.2 , pp. 89-96
    • Marti, E.1    Bovolenta, P.2
  • 67
    • 0029422299 scopus 로고
    • Regulation of Oct-4 gene expression during differentiation of EC cells
    • Schoorlemmer J, Jonk L, Shen S, et al. Regulation of Oct-4 gene expression during differentiation of EC cells. Mol Biol Reports. 1995;21:129-140.
    • (1995) Mol Biol Reports , vol.21 , pp. 129-140
    • Schoorlemmer, J.1    Jonk, L.2    Shen, S.3
  • 68
    • 0345120945 scopus 로고    scopus 로고
    • The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development
    • Pereira FA, Qiu Y, Zhou G, et al. The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development. Genes Dev. 1999;13(8):1037-1049.
    • (1999) Genes Dev , vol.13 , Issue.8 , pp. 1037-1049
    • Pereira, F.A.1    Qiu, Y.2    Zhou, G.3
  • 69
    • 10044255446 scopus 로고    scopus 로고
    • The nuclear orphan receptor COUP-TFII is required for limb and skeletal muscle development
    • Lee CT, Li L, Takamoto N, et al. The nuclear orphan receptor COUP-TFII is required for limb and skeletal muscle development. Mol Cell Biol. 2004;24(24):10835-10843.
    • (2004) Mol Cell Biol , vol.24 , Issue.24 , pp. 10835-10843
    • Lee, C.T.1    Li, L.2    Takamoto, N.3
  • 70
    • 0030858661 scopus 로고    scopus 로고
    • Null mutation of mCOUPTFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization
    • Qiu Y, Pereira FA, DeMayo FJ, et al. Null mutation of mCOUPTFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization. Genes Dev. 1997; 11(15):1925-1937.
    • (1997) Genes Dev , vol.11 , Issue.15 , pp. 1925-1937
    • Qiu, Y.1    Pereira, F.A.2    Demayo, F.J.3
  • 71
    • 20944437352 scopus 로고    scopus 로고
    • Essential role of chicken ovalbumin upstream promoter-transcription factor II in insulin secretion and insulin sensitivity revealed by conditional gene knockout
    • Bardoux P, Zhang P, Flamez D, et al. Essential role of chicken ovalbumin upstream promoter-transcription factor II in insulin secretion and insulin sensitivity revealed by conditional gene knockout. Diabetes. 2005;54(5):1357-1363.
    • (2005) Diabetes , vol.54 , Issue.5 , pp. 1357-1363
    • Bardoux, P.1    Zhang, P.2    Flamez, D.3
  • 72
    • 40649091407 scopus 로고    scopus 로고
    • The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis
    • Xu Z, Yu S, Hsu CH. The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis. Proc Natl Acad Sci USA. 2008;105(7):2421-2426.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.7 , pp. 2421-2426
    • Xu, Z.1    Yu, S.2    Hsu, C.H.3
  • 73
    • 0029131189 scopus 로고
    • Chicken ovalbumin upstream promoter transcription factor (COUP-TF): Expression during mouse embryogenesis
    • Pereira FA, Qiu Y, Tsai MJ, Tsai SY. Chicken ovalbumin upstream promoter transcription factor (COUP-TF): expression during mouse embryogenesis. J Steroid Biochem Mol Biol. 1995;53: 503-508.
    • (1995) J Steroid Biochem Mol Biol , vol.53 , pp. 503-508
    • Pereira, F.A.1    Qiu, Y.2    Tsai, M.J.3    Tsai, S.Y.4
  • 74
    • 50249103813 scopus 로고    scopus 로고
    • Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development
    • Naka H, Nakamura S, Shimazaki T, Okano H. Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development. Nat Neurosci. 2008;11(9):1014-1023.
    • (2008) Nat Neurosci , vol.11 , Issue.9 , pp. 1014-1023
    • Naka, H.1    Nakamura, S.2    Shimazaki, T.3    Okano, H.4
  • 75
    • 0029784322 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a mouse nuclear orphan receptor expressed in embryos and testes
    • Lee CH, Chang L, Wei LN. Molecular cloning and characterization of a mouse nuclear orphan receptor expressed in embryos and testes. Mol Reprod Dev. 1996;44(3):305-314.
    • (1996) Mol Reprod Dev , vol.44 , Issue.3 , pp. 305-314
    • Lee, C.H.1    Chang, L.2    Wei, L.N.3
  • 76
    • 0031049093 scopus 로고    scopus 로고
    • Dictinct expression patterns and biological activities of two isoforms of the mouse orphan receptor TR2
    • Lee CH, Chang L, Wei LN. Dictinct expression patterns and biological activities of two isoforms of the mouse orphan receptor TR2. J Endocrinol. 1997;152(2):245-255.
    • (1997) J Endocrinol , vol.152 , Issue.2 , pp. 245-255
    • Lee, C.H.1    Chang, L.2    Wei, L.N.3
  • 77
    • 0036701576 scopus 로고    scopus 로고
    • Recent advances in the TR2 and TR4 orphan receptors of the nuclear receptor superfamily
    • Lee YF, Lee HJ, Chang C. Recent advances in the TR2 and TR4 orphan receptors of the nuclear receptor superfamily. J Steroid Biochem Mol Biol. 2002;81:291-308.
    • (2002) J Steroid Biochem Mol Biol , vol.81 , pp. 291-308
    • Lee, Y.F.1    Lee, H.J.2    Chang, C.3
  • 78
    • 0031741654 scopus 로고    scopus 로고
    • Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2
    • Lee CH, Chinpaisal C, Wei LN. Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2. Mol Cell Biol. 1998;18(11):6745-6755.
    • (1998) Mol Cell Biol , vol.18 , Issue.11 , pp. 6745-6755
    • Lee, C.H.1    Chinpaisal, C.2    Wei, L.N.3
  • 79
    • 33846114807 scopus 로고    scopus 로고
    • SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells
    • Park SW, Hu X, Gupta P, et al. SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells. Nat Struct Mol Biol. 2007;14(1):68-75.
    • (2007) Nat Struct Mol Biol , vol.14 , Issue.1 , pp. 68-75
    • Park, S.W.1    Hu, X.2    Gupta, P.3
  • 80
    • 49649090416 scopus 로고    scopus 로고
    • Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression
    • Gupta P, Ho PC, Huq MM, et al. Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression. Proc Natl Acad Sci USA. 2008;105:11424-11429.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 11424-11429
    • Gupta, P.1    Ho, P.C.2    Huq, M.M.3
  • 81
    • 0036273906 scopus 로고    scopus 로고
    • Spermatogenesis and testis development are normal in mice lacking testicular orphan nuclear receptor 2
    • Shyr CR, Collins LL, Mu XM, et al. Spermatogenesis and testis development are normal in mice lacking testicular orphan nuclear receptor 2. Mol Cell Biol. 2002;22:4661-4666.
    • (2002) Mol Cell Biol , vol.22 , pp. 4661-4666
    • Shyr, C.R.1    Collins, L.L.2    Mu, X.M.3
  • 82
    • 13544259457 scopus 로고    scopus 로고
    • The DEAD-box protein DP103 (Ddx20 or Gemin-3) represses orphan nuclear receptor activity via SUMO modification
    • Lee MB, Lebedeva LA, Suzawa M, et al. The DEAD-box protein DP103 (Ddx20 or Gemin-3) represses orphan nuclear receptor activity via SUMO modification. Mol Cell Biol. 2005;25(5): 1879-1890.
    • (2005) Mol Cell Biol , vol.25 , Issue.5 , pp. 1879-1890
    • Lee, M.B.1    Lebedeva, L.A.2    Suzawa, M.3
  • 83
    • 67649112104 scopus 로고    scopus 로고
    • Oct4: Less is more
    • Wagner RT, Cooney AJ. Oct4: less is more. Cell Res. 2009;19(5): 527-528.
    • (2009) Cell Res , vol.19 , Issue.5 , pp. 527-528
    • Wagner, R.T.1    Cooney, A.J.2
  • 84
    • 0035167634 scopus 로고    scopus 로고
    • Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and novel posterior truncation
    • Chung AC, Katz D, Pereira FA, et al. Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and novel posterior truncation. Mol Cell Biol. 2001;21: 663-677.
    • (2001) Mol Cell Biol , vol.21 , pp. 663-677
    • Chung, A.C.1    Katz, D.2    Pereira, F.A.3
  • 85
    • 0343204352 scopus 로고    scopus 로고
    • The germ cell nuclear factor mGCNF is expressed in the developming nervous system
    • Süsens U, Aguiluz JB, Evans RM, Borgmeyer U. The germ cell nuclear factor mGCNF is expressed in the developming nervous system. Dev Neurosci. 1997;19:410-420.
    • (1997) Dev Neurosci , vol.19 , pp. 410-420
    • Süsens, U.1    Aguiluz, J.B.2    Evans, R.M.3    Borgmeyer, U.4
  • 86
    • 0030967435 scopus 로고    scopus 로고
    • Characterization of germ cell-specific expression of the orphan nuclear receptor, germ cell nuclear factor
    • Katz D, Niederberger C, Slaughter GR, Cooney AJ. Characterization of germ cell-specific expression of the orphan nuclear receptor, germ cell nuclear factor. Endocrinology. 1997;138:4364-4372.
    • (1997) Endocrinology , vol.138 , pp. 4364-4372
    • Katz, D.1    Niederberger, C.2    Slaughter, G.R.3    Cooney, A.J.4
  • 87
    • 0035460556 scopus 로고    scopus 로고
    • Mouse germline restriction of Oct4 expression by germ cell nuclear factor
    • Fuhrmann G, Chung AC, Jackson K, et al. Mouse germline restriction of Oct4 expression by germ cell nuclear factor. Dev Cell. 2001;1(3):377-387.
    • (2001) Dev Cell , vol.1 , Issue.3 , pp. 377-387
    • Fuhrmann, G.1    Chung, A.C.2    Jackson, K.3
  • 88
    • 0037184932 scopus 로고    scopus 로고
    • The embryonic function of germ cell nuclear factor is dependent on theDNAbinding domain
    • Lan ZJ, Chung AC, Xu X, et al. The embryonic function of germ cell nuclear factor is dependent on theDNAbinding domain. J Biol Chem. 2002;277(52):50660-50667.
    • (2002) J Biol Chem , vol.277 , Issue.52 , pp. 50660-50667
    • Lan, Z.J.1    Chung, A.C.2    Xu, X.3
  • 89
    • 0034634535 scopus 로고    scopus 로고
    • Characterization of the repressor function of the nuclear orphan receptor retinoid receptor-related testis-associated receptor/germ cell nuclear factor
    • Yan Z, Jetten AM. Characterization of the repressor function of the nuclear orphan receptor retinoid receptor-related testis-associated receptor/germ cell nuclear factor. J Biol Chem. 2000; 275(45):35077-35085.
    • (2000) J Biol Chem , vol.275 , Issue.45 , pp. 35077-35085
    • Yan, Z.1    Jetten, A.M.2
  • 90
    • 24744465868 scopus 로고    scopus 로고
    • Evolutionary trace-based peptides identify a novel asymmetric interaction that mediates oligomerization in nuclear receptors
    • Gu P, Morgan DH, Sattar M, et al. Evolutionary trace-based peptides identify a novel asymmetric interaction that mediates oligomerization in nuclear receptors. J Biol Chem. 2005;280(36): 31818-31829.
    • (2005) J Biol Chem , vol.280 , Issue.36 , pp. 31818-31829
    • Gu, P.1    Morgan, D.H.2    Sattar, M.3
  • 91
    • 79960098405 scopus 로고    scopus 로고
    • Differential recruitment of methyl CpG-binding factors and DNA methyltransferases by the orphan receptor germ cell nuclear factor initiates the repression and silencing of Oct4
    • Gu P, Xu X, Le Menuet D, Chung AC, Cooney AJ. Differential recruitment of methyl CpG-binding factors and DNA methyltransferases by the orphan receptor germ cell nuclear factor initiates the repression and silencing of Oct4. Stem Cells. 2011;29(7): 1041-1051.
    • (2011) Stem Cells , vol.29 , Issue.7 , pp. 1041-1051
    • Gu, P.1    Xu, X.2    Le Menuet, D.3    Chung, A.C.4    Cooney, A.J.5
  • 92
    • 33646494025 scopus 로고    scopus 로고
    • The orphan nuclear receptor GCNF recruits DNA methyltransferase for Oct-3/4 silencing
    • Sato N, Kondo M, Arai K. The orphan nuclear receptor GCNF recruits DNA methyltransferase for Oct-3/4 silencing. Biochem Biophys Res Commun. 2006;344(3):845-851.
    • (2006) Biochem Biophys Res Commun , vol.344 , Issue.3 , pp. 845-851
    • Sato, N.1    Kondo, M.2    Arai, K.3
  • 93
    • 33644764030 scopus 로고    scopus 로고
    • The NuRD component of Mbd3 is required for pluripotency of embryonic stem cells
    • Kaji K, Caballero IM, MacLeod R, et al. The NuRD component of Mbd3 is required for pluripotency of embryonic stem cells. Nat Cell Biol. 2006;8(3):285-292.
    • (2006) Nat Cell Biol , vol.8 , Issue.3 , pp. 285-292
    • Kaji, K.1    Caballero, I.M.2    Macleod, R.3
  • 94
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylationand mammalian development
    • Okano M, Bell DW, Haber DA, et al. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylationand mammalian development. Cell. 1999;99:247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3
  • 95
    • 0042132027 scopus 로고    scopus 로고
    • Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
    • Chen T, Ueda Y, Dodge JE, et al. Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol Cell Biol. 2003;23(16): 5594-5605.
    • (2003) Mol Cell Biol , vol.23 , Issue.16 , pp. 5594-5605
    • Chen, T.1    Ueda, Y.2    Dodge, J.E.3
  • 96
    • 37549015214 scopus 로고    scopus 로고
    • Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog
    • Li JY, Pu MT, Hirasawa R, et al. Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog. Mol Cell Biol. 2007;27(24):8748-8759.
    • (2007) Mol Cell Biol , vol.27 , Issue.24 , pp. 8748-8759
    • Li, J.Y.1    Pu, M.T.2    Hirasawa, R.3
  • 97
    • 75349088911 scopus 로고    scopus 로고
    • The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells
    • Heng JC, Feng B, Han J, et al. The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells. Cell Stem Cell. 2010;6(2):167-174.
    • (2010) Cell Stem Cell , vol.6 , Issue.2 , pp. 167-174
    • Heng, J.C.1    Feng, B.2    Han, J.3
  • 98
    • 59649105969 scopus 로고    scopus 로고
    • Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb
    • Feng B, Jiang J, Kraus P, et al. Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb. Nat Cell Biol. 2009;11(2):197-203.
    • (2009) Nat Cell Biol , vol.11 , Issue.2 , pp. 197-203
    • Feng, B.1    Jiang, J.2    Kraus, P.3
  • 99
    • 2342459110 scopus 로고    scopus 로고
    • LRH-1: An orphan nuclear receptor involved in development, metabolism, and steroidogenesis
    • Fayard E, Auxerx J, Schoonjans K. LRH-1: an orphan nuclear receptor involved in development, metabolism, and steroidogenesis. Trends Cell Biol. 2004;14(5):250-260.
    • (2004) Trends Cell Biol , vol.14 , Issue.5 , pp. 250-260
    • Fayard, E.1    Auxerx, J.2    Schoonjans, K.3
  • 100
    • 0029014274 scopus 로고
    • A cell-specific nuclear receptor plays essential roles in adrenal and gonadal development
    • Luo X, Ikeda Y, Lala DS, et al. A cell-specific nuclear receptor plays essential roles in adrenal and gonadal development. Endocr Res. 1995;21:517-524.
    • (1995) Endocr Res , vol.21 , pp. 517-524
    • Luo, X.1    Ikeda, Y.2    Lala, D.S.3
  • 101
    • 2442676745 scopus 로고    scopus 로고
    • The fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 element
    • Pare JF, Malenfant D, Couremanche C, et al. The fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 element. J Biol Chem. 2004;279:21206-21216.
    • (2004) J Biol Chem , vol.279 , pp. 21206-21216
    • Pare, J.F.1    Malenfant, D.2    Couremanche, C.3
  • 102
    • 0042335826 scopus 로고    scopus 로고
    • Expression of LRH-1 and SF-1 in the mouse ovary: Localization in different cell types correlates with differing function
    • Hinshelwood MM, Repa JJ, Shelton JM, et al. Expression of LRH-1 and SF-1 in the mouse ovary: localization in different cell types correlates with differing function. Mol Cell Endocrinol. 2003;207:39-45.
    • (2003) Mol Cell Endocrinol , vol.207 , pp. 39-45
    • Hinshelwood, M.M.1    Repa, J.J.2    Shelton, J.M.3
  • 103
    • 0027295482 scopus 로고
    • Characterization of the mouse FTZ-F1 gene which encodes a key regulator of steroid hydroxylase gene expression
    • Ikeda Y, Lala DS, Luo X, et al. Characterization of the mouse FTZ-F1 gene which encodes a key regulator of steroid hydroxylase gene expression. Mol Endocrinol. 1993;7(7):852-860.
    • (1993) Mol Endocrinol , vol.7 , Issue.7 , pp. 852-860
    • Ikeda, Y.1    Lala, D.S.2    Luo, X.3
  • 104
    • 0027971944 scopus 로고
    • The nuclear receptor steroidogenic factor-1 acts at multiple levels of the reproductive axis
    • Ingraham HA, Lala DS, Ikeda Y, et al. The nuclear receptor steroidogenic factor-1 acts at multiple levels of the reproductive axis. Genes Dev. 1994; 8(19):2302-2312.
    • (1994) Genes Dev , vol.8 , Issue.19 , pp. 2302-2312
    • Ingraham, H.A.1    Lala, D.S.2    Ikeda, Y.3
  • 105
    • 44649183963 scopus 로고    scopus 로고
    • Stem cell-specific expression of Dax1 is conferred by STAT3 and Oct3/4 in embryonic stem cells
    • Sun C, Nakatake Y, Ura H, et al. Stem cell-specific expression of Dax1 is conferred by STAT3 and Oct3/4 in embryonic stem cells. Biochem Biophys Res Commun. 2008;372:91-96.
    • (2008) Biochem Biophys Res Commun , vol.372 , pp. 91-96
    • Sun, C.1    Nakatake, Y.2    Ura, H.3
  • 106
    • 0030920333 scopus 로고    scopus 로고
    • Nuclear receptor steroidogenic factor-1 directs embryonic stem cells toward the steroidogenic lineage
    • Crawford PA, Sadovsky Y, Milbrandt J. Nuclear receptor steroidogenic factor-1 directs embryonic stem cells toward the steroidogenic lineage. Mol Cell Biol. 1997;17(7):3997-4006.
    • (1997) Mol Cell Biol , vol.17 , Issue.7 , pp. 3997-4006
    • Crawford, P.A.1    Sadovsky, Y.2    Milbrandt, J.3
  • 107
    • 33845366619 scopus 로고    scopus 로고
    • Nuclear receptor NR5A2 is required for proper primitive streak morphogenesis
    • Labelle-Dumais C, Jacob-Wagner M, Pare JF, et al. Nuclear receptor NR5A2 is required for proper primitive streak morphogenesis. Dev Dyn. 2006;235:3359-3369.
    • (2006) Dev Dyn , vol.235 , pp. 3359-3369
    • Labelle-Dumais, C.1    Jacob-Wagner, M.2    Pare, J.F.3
  • 108
    • 78149337402 scopus 로고    scopus 로고
    • Canonical Wnt/catenin regulation of liver receptor homolog-1 (Lrh-1) mediates pluripotency gene expression
    • Wagner RT, Xu X, Yi F, et al. Canonical Wnt/catenin regulation of liver receptor homolog-1 (Lrh-1) mediates pluripotency gene expression. Stem Cells. 2010;28(10):1794-1804.
    • (2010) Stem Cells , vol.28 , Issue.10 , pp. 1794-1804
    • Wagner, R.T.1    Xu, X.2    Yi, F.3
  • 110
    • 0028971954 scopus 로고
    • Lack of _-catenin affects mouse development at gastrulation
    • Haegel H, Larue L, Ohsugi M, et al. Lack of _-catenin affects mouse development at gastrulation. Development. 1995;121: 3529-3537.
    • (1995) Development , vol.121 , pp. 3529-3537
    • Haegel, H.1    Larue, L.2    Ohsugi, M.3
  • 111
    • 0031848068 scopus 로고    scopus 로고
    • Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
    • Korinek V, Barker N, Moerer P, et al. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet. 1998;19:379-383.
    • (1998) Nat Genet , vol.19 , pp. 379-383
    • Korinek, V.1    Barker, N.2    Moerer, P.3
  • 112
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signaling in self-renewal of haematopoietic stem cells
    • Reya T, Duncan AW, Ailles L, et al. A role for Wnt signaling in self-renewal of haematopoietic stem cells. Nature. 2003;423:409-414.
    • (2003) Nature , vol.423 , pp. 409-414
    • Reya, T.1    Duncan, A.W.2    Ailles, L.3
  • 113
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
    • Sato N, Meijer L, Skaltsounis L, et al. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med. 2004;10:55-63.
    • (2004) Nat Med , vol.10 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3
  • 114
    • 33645097331 scopus 로고    scopus 로고
    • Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells
    • Ogawa K, Nishinakamura R, Iwamatsu Y, et al. Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells. Biochem Biophys Res Commun. 2006;343:159-166.
    • (2006) Biochem Biophys Res Commun , vol.343 , pp. 159-166
    • Ogawa, K.1    Nishinakamura, R.2    Iwamatsu, Y.3
  • 115
    • 33846251988 scopus 로고    scopus 로고
    • Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions
    • Cai L, Ye Z, Zhou BY, et al. Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions. Cell Res. 2007;17:62-72.
    • (2007) Cell Res , vol.17 , pp. 62-72
    • Cai, L.1    Ye, Z.2    Zhou, B.Y.3
  • 116
    • 33644916387 scopus 로고    scopus 로고
    • Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter
    • Gao DM, Wang LF, Liu J, et al. Expression of mouse liver receptor homologue 1 in embryonic stem cells is directed by a novel promoter. FEBS Lett. 2006;580:1702-1708.
    • (2006) FEBS Lett , vol.580 , pp. 1702-1708
    • Gao, D.M.1    Wang, L.F.2    Liu, J.3
  • 117
    • 67650032868 scopus 로고    scopus 로고
    • A parallel circuit of LIF signaling pathways maintains pluripotency of mouse ES cells
    • Niwa H, Ogawa K, Shimosato D, et al. A parallel circuit of LIF signaling pathways maintains pluripotency of mouse ES cells. Nature. 2009;460:118-122.
    • (2009) Nature , vol.460 , pp. 118-122
    • Niwa, H.1    Ogawa, K.2    Shimosato, D.3
  • 118
    • 0026768292 scopus 로고
    • Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor
    • Stewart CL, Kaspar P, Brunet LJ, et al. Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor. Nature. 1992; 359:76-79.
    • (1992) Nature , vol.359 , pp. 76-79
    • Stewart, C.L.1    Kaspar, P.2    Brunet, L.J.3
  • 119
    • 0034944121 scopus 로고    scopus 로고
    • Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines
    • Nichols J, Chambers I, Taga T, et al. Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines. Development. 2001;128:2333-2339.
    • (2001) Development , vol.128 , pp. 2333-2339
    • Nichols, J.1    Chambers, I.2    Taga, T.3
  • 120
    • 44349170450 scopus 로고    scopus 로고
    • The ground state of embryonic stem cell self-renewal
    • Ying QL, Wray J, Nichols J, et al. The ground state of embryonic stem cell self-renewal. Nature. 2008;453:519-523.
    • (2008) Nature , vol.453 , pp. 519-523
    • Ying, Q.L.1    Wray, J.2    Nichols, J.3
  • 121
    • 68749110887 scopus 로고    scopus 로고
    • Nanog is the gateway to the pluripotent ground state
    • Silva J, Nichols J, Theunissen TW, et al. Nanog is the gateway to the pluripotent ground state. Cell. 2009;138:722-737.
    • (2009) Cell , vol.138 , pp. 722-737
    • Silva, J.1    Nichols, J.2    Theunissen, T.W.3
  • 122
    • 66049136895 scopus 로고    scopus 로고
    • Klf4 reverts developmentally programmed restriction of ground state pluripotency
    • Guo G, Yang J, Nichols J, et al. Klf4 reverts developmentally programmed restriction of ground state pluripotency. Development 2009;136:1063-1069.
    • (2009) Development , vol.136 , pp. 1063-1069
    • Guo, G.1    Yang, J.2    Nichols, J.3
  • 123
    • 77956199358 scopus 로고    scopus 로고
    • Stat3 activation is limiting for reprogramming to ground state pluripotency
    • Yang J, van Oosten AL, Theunissen TW, et al. Stat3 activation is limiting for reprogramming to ground state pluripotency. Cell Stem Cell. 2010;7:319-328.
    • (2010) Cell Stem Cell , vol.7 , pp. 319-328
    • Yang, J.1    van Oosten, A.L.2    Theunissen, T.W.3
  • 124
    • 77956566519 scopus 로고    scopus 로고
    • A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency
    • Guo G, Smith A. A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency. Development. 2010;137:3185-3192.
    • (2010) Development , vol.137 , pp. 3185-3192
    • Guo, G.1    Smith, A.2
  • 125
    • 0043268895 scopus 로고    scopus 로고
    • DAX-1, an unusual orphan receptor at the crossroads of steroidogenic function and sexual differentiation
    • Lalli E, Sassone-Corsi P. DAX-1, an unusual orphan receptor at the crossroads of steroidogenic function and sexual differentiation. Mol Endocrinol. 2003;17:1445-1453.
    • (2003) Mol Endocrinol , vol.17 , pp. 1445-1453
    • Lalli, E.1    Sassone-Corsi, P.2
  • 126
    • 0030780854 scopus 로고    scopus 로고
    • A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypoplasia congenital
    • Lalli E, Bardoni B, Zazopoulos E, et al. A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypoplasia congenital. Mol Endocrinol. 11:1950-1960.
    • Mol Endocrinol , vol.11 , pp. 1950-1960
    • Lalli, E.1    Bardoni, B.2    Zazopoulos, E.3
  • 127
    • 0032546009 scopus 로고    scopus 로고
    • Dax1 antagonizes Sry action in mammalian sex determination
    • Swain A, Narvaez V, Burgoyne P, et al. Dax1 antagonizes Sry action in mammalian sex determination. Nature. 1998;391:761-767.
    • (1998) Nature , vol.391 , pp. 761-767
    • Swain, A.1    Narvaez, V.2    Burgoyne, P.3
  • 128
    • 0028558750 scopus 로고
    • An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita
    • Zanaria E, Muscatelli F, Bardoni B, et al. An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita. Nature. 1994;372:635-641.
    • (1994) Nature , vol.372 , pp. 635-641
    • Zanaria, E.1    Muscatelli, F.2    Bardoni, B.3
  • 129
    • 0028598360 scopus 로고
    • Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism
    • Muscatelli F, Strom TM, Walker AP, et al. Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism. Nature. 1994;372: 672-676.
    • (1994) Nature , vol.372 , pp. 672-676
    • Muscatelli, F.1    Strom, T.M.2    Walker, A.P.3
  • 130
    • 0344665721 scopus 로고    scopus 로고
    • Nr0b1 and its network partners are expressed early in murine embryos prior to steroidogenic axis organogenesis
    • Clipsham R, Niakan K, McCabe ER. Nr0b1 and its network partners are expressed early in murine embryos prior to steroidogenic axis organogenesis. Gene Expr Patterns. 2004;4:3-14.
    • (2004) Gene Expr Patterns , vol.4 , pp. 3-14
    • Clipsham, R.1    Niakan, K.2    McCabe, E.R.3
  • 131
    • 33745483831 scopus 로고    scopus 로고
    • Novel role for the orphan nuslear receptor Dax1 in embryogenesis, different from steroidogenesis
    • Niakan KK, Davis EC, Clipsham RC, et al. Novel role for the orphan nuslear receptor Dax1 in embryogenesis, different from steroidogenesis. Mol Genet Metab. 2006;88:261-271.
    • (2006) Mol Genet Metab , vol.88 , pp. 261-271
    • Niakan, K.K.1    Davis, E.C.2    Clipsham, R.C.3
  • 132
    • 79959560633 scopus 로고    scopus 로고
    • A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects
    • Lee JM, Lee YK, Mamrosh JL, et al. A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. Nature. 2011;474:506-510.
    • (2011) Nature , vol.474 , pp. 506-510
    • Lee, J.M.1    Lee, Y.K.2    Mamrosh, J.L.3
  • 133
    • 44649183963 scopus 로고    scopus 로고
    • Stem cell-specific expression of Dax1 is conferred by STAT3 and Oct3/4 in embryonic stem cells
    • Sun C, Nakatake Y, Ura H, et al. Stem cell-specific expression of Dax1 is conferred by STAT3 and Oct3/4 in embryonic stem cells. Biochem Biophys Res Commun. 2008;372:91-96.
    • (2008) Biochem Biophys Res Commun , vol.372 , pp. 91-96
    • Sun, C.1    Nakatake, Y.2    Ura, H.3
  • 134
    • 33751092246 scopus 로고    scopus 로고
    • A protein interaction network for pluripotency of embryonic stem cells
    • Wang J, Rao S, Chu J, et al. A protein interaction network for pluripotency of embryonic stem cells. Nature. 2006;444:364-368.
    • (2006) Nature , vol.444 , pp. 364-368
    • Wang, J.1    Rao, S.2    Chu, J.3
  • 135
    • 40749104852 scopus 로고    scopus 로고
    • An extended transcriptional network for pluripotency of embryonic stem cells
    • Kim J, Chu J, Shen X, et al. An extended transcriptional network for pluripotency of embryonic stem cells. Cell. 2008;132:1049-1061.
    • (2008) Cell , vol.132 , pp. 1049-1061
    • Kim, J.1    Chu, J.2    Shen, X.3
  • 136
    • 68949149685 scopus 로고    scopus 로고
    • Dax1 binds to Oct3/4 and inhibits its transcriptional activity in embryonic stem cells
    • Sun C, Nakatake Y, Akagi T, et al. Dax1 binds to Oct3/4 and inhibits its transcriptional activity in embryonic stem cells. Mol Cell Biol. 2009;29:4574-4583.
    • (2009) Mol Cell Biol , vol.29 , pp. 4574-4583
    • Sun, C.1    Nakatake, Y.2    Akagi, T.3
  • 137
    • 77949900026 scopus 로고    scopus 로고
    • An Oct4-centered protein interaction network in embryonic stem cells
    • van den Berg DL, Snoek T, Mullin NP, et al. An Oct4-centered protein interaction network in embryonic stem cells. Cell Stem Cell. 2010;6:369-381.
    • (2010) Cell Stem Cell , vol.6 , pp. 369-381
    • van den Berg, D.L.1    Snoek, T.2    Mullin, N.P.3
  • 138
    • 0023857147 scopus 로고
    • Identification of a new class of steroid hormone receptor
    • Giguere V, Yang N, Segui P, Evans RM. Identification of a new class of steroid hormone receptor. Nature. 1988;331:91-94.
    • (1988) Nature , vol.331 , pp. 91-94
    • Giguere, V.1    Yang, N.2    Segui, P.3    Evans, R.M.4
  • 139
    • 33646146500 scopus 로고    scopus 로고
    • Estrogen-related receptors as emerging targets in cancer and metabolic disorders
    • Ariazi EA, Jordan VC. Estrogen-related receptors as emerging targets in cancer and metabolic disorders. Curr Top Med Chem. 2006;6:203-215.
    • (2006) Curr Top Med Chem , vol.6 , pp. 203-215
    • Ariazi, E.A.1    Jordan, V.C.2
  • 140
    • 0030062628 scopus 로고    scopus 로고
    • Expression of a novel member of estrogen response element-binding nuclear receptors is restricted to the early stages of chorion formation during mouse embryogenesis
    • Pettersson K, Svensson K, Mattsson R, et al. Expression of a novel member of estrogen response element-binding nuclear receptors is restricted to the early stages of chorion formation during mouse embryogenesis. Mech Dev. 54:211-223.
    • Mech Dev , vol.54 , pp. 211-223
    • Pettersson, K.1    Svensson, K.2    Mattsson, R.3
  • 141
    • 0030869565 scopus 로고    scopus 로고
    • Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-_
    • Luo J, Sladek R, Bader JA, et al. Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-_. Nature. 1997;388:778-782.
    • (1997) Nature , vol.388 , pp. 778-782
    • Luo, J.1    Sladek, R.2    Bader, J.A.3
  • 142
    • 1442299168 scopus 로고    scopus 로고
    • Loss of PGC-specific expression of the orphan nuclear receptor ERR-_ results in reduction of germ cell number in mouse embryos
    • Mitsunaga K, Araki K, Mizusaki H, et al. Loss of PGC-specific expression of the orphan nuclear receptor ERR-_ results in reduction of germ cell number in mouse embryos. Mech Dev. 2004;121: 237-246.
    • (2004) Mech Dev , vol.121 , pp. 237-246
    • Mitsunaga, K.1    Araki, K.2    Mizusaki, H.3
  • 143
    • 33746773659 scopus 로고    scopus 로고
    • Dissecting self-renewal in stem cells with RNA interference
    • Ivanova N, Dobrin R, Lu R, et al. Dissecting self-renewal in stem cells with RNA interference. Nature. 2006;442:533-538.
    • (2006) Nature , vol.442 , pp. 533-538
    • Ivanova, N.1    Dobrin, R.2    Lu, R.3
  • 144
    • 0344011490 scopus 로고    scopus 로고
    • Flavone and isoflavone phytoestrogens are agonists of estrogen-related receptors
    • Suetsugi M, Su L, Karlsberg K, et al. Flavone and isoflavone phytoestrogens are agonists of estrogen-related receptors. Mol Cancer Res 2003;1:981-991.
    • (2003) Mol Cancer Res , vol.1 , pp. 981-991
    • Suetsugi, M.1    Su, L.2    Karlsberg, K.3
  • 145
    • 52649136596 scopus 로고    scopus 로고
    • Estrogen-related receptor _ interacts with Oct4 to positively regulate Nanog gene expression
    • van den Berg DL, Zhang W, Yates A, et al. Estrogen-related receptor _ interacts with Oct4 to positively regulate Nanog gene expression. Mol Cell Biol. 2008;28:5986-5995.
    • (2008) Mol Cell Biol , vol.28 , pp. 5986-5995
    • van den Berg, D.L.1    Zhang, W.2    Yates, A.3
  • 146
    • 34247154612 scopus 로고    scopus 로고
    • Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells
    • Storm MP, Bone HK, Beck CG, et al. Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells. J Biol Chem. 282:6265-6273.
    • J Biol Chem , vol.282 , pp. 6265-6273
    • Storm, M.P.1    Bone, H.K.2    Beck, C.G.3
  • 147
    • 58149104232 scopus 로고    scopus 로고
    • Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells
    • Zhang X, Zhang J, Wang T, et al. Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells. J Biol Chem. 2008;283:35825-35833.
    • (2008) J Biol Chem , vol.283 , pp. 35825-35833
    • Zhang, X.1    Zhang, J.2    Wang, T.3
  • 148
    • 13944262909 scopus 로고    scopus 로고
    • A germ cell origin of embryonic stem cells?
    • Zwaka TP, Thomson JA. A germ cell origin of embryonic stem cells? Development. 2005;132:227-233.
    • (2005) Development , vol.132 , pp. 227-233
    • Zwaka, T.P.1    Thomson, J.A.2
  • 149
    • 84867381511 scopus 로고    scopus 로고
    • Esrrb is a direct Nanog target gene that can substitute for Nanog function in pluripotent cells
    • Festuccia N, Osorno R, Halbritter F, et al. Esrrb is a direct Nanog target gene that can substitute for Nanog function in pluripotent cells. Cell Stem Cell 2012;11(4):477-490.
    • (2012) Cell Stem Cell , vol.11 , Issue.4 , pp. 477-490
    • Festuccia, N.1    Osorno, R.2    Halbritter, F.3
  • 150
    • 84867387161 scopus 로고    scopus 로고
    • Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal
    • Martello G, Sugimoto T, Diamanti E, et al. Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewal. Cell Stem Cell. 2012;11(4): 491-504.
    • (2012) Cell Stem Cell , vol.11 , Issue.4 , pp. 491-504
    • Martello, G.1    Sugimoto, T.2    Diamanti, E.3
  • 151
    • 66649100583 scopus 로고    scopus 로고
    • Expression profiling of nuclear receptors in human and mouse embryonic stem cells
    • Xie CQ, Jeong Y, Fu M, et al. Expression profiling of nuclear receptors in human and mouse embryonic stem cells. Mol Endocrinol. 2009;23:724-733.
    • (2009) Mol Endocrinol , vol.23 , pp. 724-733
    • Xie, C.Q.1    Jeong, Y.2    Fu, M.3
  • 152
    • 65649116572 scopus 로고    scopus 로고
    • Human induced pluripotent stem cells free of vector and transgene sequences
    • Yu J, Hu K, Smuga-Otto K, et al. Human induced pluripotent stem cells free of vector and transgene sequences. Science. 2009;324: 797-801.
    • (2009) Science , vol.324 , pp. 797-801
    • Yu, J.1    Hu, K.2    Smuga-Otto, K.3
  • 153
    • 66049143859 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
    • Kim D, Kim CH, Moon JL, et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell. 2009;4:472-476.
    • (2009) Cell Stem Cell , vol.4 , pp. 472-476
    • Kim, D.1    Kim, C.H.2    Moon, J.L.3
  • 154
    • 64749083939 scopus 로고    scopus 로고
    • Piggy Bac transposition reprograms fibroblasts to induced pluripotent stem cells
    • Woltjen K, Michael IP, Mohseni P, et al. Piggy Bac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature. 2009;458:766-770.
    • (2009) Nature , vol.458 , pp. 766-770
    • Woltjen, K.1    Michael, I.P.2    Mohseni, P.3
  • 155
    • 33751009392 scopus 로고    scopus 로고
    • Identification of small molecule agonists of the orphan nuclear receptors liver receptor homolog-1 and steroidogenic factor-1
    • Whitby RJ, Dixon S, Maloney PR, et al. Identification of small molecule agonists of the orphan nuclear receptors liver receptor homolog-1 and steroidogenic factor-1. J Med Chem. 2006;49:6652-6655.
    • (2006) J Med Chem , vol.49 , pp. 6652-6655
    • Whitby, R.J.1    Dixon, S.2    Maloney, P.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.