-
1
-
-
0027756145
-
Sonic hedgehog, a member of a family of putative signalling molecules, is implicated in regulation of CNS polarity
-
(1993)
Cell
, vol.75
, pp. 1417-1430
-
-
Echelard, Y.1
-
2
-
-
0027749249
-
A functionally conserved homologue of the Drosophila segment polarity gene hedgehog is expressed in tissues with polarising activity in zebrafish embryo
-
(1993)
Cell
, vol.75
, pp. 1431-1444
-
-
Krauss, S.1
-
3
-
-
0027760995
-
Sonic hedgehog mediates the polarising activity of the ZPA
-
(1993)
Cell
, vol.75
, pp. 1401-1416
-
-
Riddle, R.D.1
-
4
-
-
23444440157
-
Floor plate and motor neuron induction by vhh-1, a vertebrate homologue of hedgehog expressed by the notochord
-
(1994)
Cell
, vol.76
, pp. 761-775
-
-
Roelink, H.1
-
5
-
-
0029079893
-
Distribution of Sonic hedgehog peptides in the developing chick and mouse embryo
-
(1995)
Development
, vol.121
, pp. 2537-2547
-
-
Martí, E.1
-
6
-
-
0029019627
-
Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants
-
(1995)
Nature
, vol.375
, pp. 322-325
-
-
Martí, E.1
-
7
-
-
0029004233
-
Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of Sonic hedgehog autoproteolysis
-
(1995)
Cell
, vol.81
, pp. 445-455
-
-
Roelink, H.1
-
8
-
-
0029777408
-
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
-
(1996)
Nature
, vol.383
, pp. 407-413
-
-
Chiang, C.1
-
9
-
-
0029068123
-
Sonic hedgehog induces differentiation of ventral forebrain neurons: A common signal for ventral patterning within the neural tube
-
(1995)
Cell
, vol.81
, pp. 747-756
-
-
Ericson, J.1
-
10
-
-
0029127630
-
Induction of midbrain dopaminergic neurons by Sonic hedgehog
-
(1995)
Neuron
, vol.15
, pp. 35-44
-
-
Hynes, M.A.1
-
13
-
-
0028948811
-
The product of hedgehog autoproteolytic cleavage active in local and long-range signalling
-
(1995)
Nature
, vol.374
, pp. 363-366
-
-
Porter, J.A.1
-
15
-
-
15844386540
-
Hedgehog patterning activity: Role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain
-
(1996)
Cell
, vol.86
, pp. 21-34
-
-
Porter, J.A.1
-
16
-
-
0029844192
-
Cholesterol modification of hedgehog signalling proteins in animal development
-
(1996)
Science
, vol.274
, pp. 255-259
-
-
Porter, J.A.1
-
17
-
-
0035860538
-
Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal
-
(2001)
Science
, vol.293
, pp. 2080-2084
-
-
Chamoun, Z.1
-
19
-
-
0035368725
-
Cholesterol modification of Sonic hedgehog is required for longrange signalling activity and effective modulation of signalling by Ptc1
-
(2001)
Cell
, vol.105
, pp. 599-612
-
-
Lewis, P.1
-
20
-
-
0035822098
-
A freely diffusible form of Sonic hedgehog mediates long-range signalling
-
(2001)
Nature
, vol.411
, pp. 716-720
-
-
Zeng, X.1
-
21
-
-
0034931149
-
N-terminal fatty-acylation of sonic hedgehog enhances the induction of ventral forebrain neurons
-
(2001)
Development
, vol.128
, pp. 2351-2363
-
-
Kohtz, J.D.1
-
22
-
-
0032126734
-
Transducing hedgehog: The story so far
-
(1998)
EMBO J.
, vol.17
, pp. 3505-3511
-
-
Ingham, P.W.1
-
26
-
-
0034721665
-
Transducing the hedgehog signal
-
(2000)
Cell
, vol.103
, pp. 371-374
-
-
Kalderon, D.1
-
27
-
-
0030027059
-
Conservation of the hedgehog/patched signalling pathway from flies to mice: Induction of a mouse patched gene by hedgehog
-
(1996)
Genes Dev.
, vol.10
, pp. 301-312
-
-
Goodrich, L.V.1
-
29
-
-
0029975823
-
Conservation in hedgehog signalling: Induction of a chicken patched homologue by Sonic hedgehog in the developing limb
-
(1996)
Development
, vol.122
, pp. 1225-1233
-
-
Marigo, V.1
-
30
-
-
0029948270
-
Biochemical evidence that patched is the hedgehog receptor
-
(1996)
Nature
, vol.384
, pp. 176-179
-
-
Marigo, V.1
-
31
-
-
0011102935
-
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
-
(1996)
Nature
, vol.384
, pp. 129-134
-
-
Stone, D.M.1
-
33
-
-
0031989439
-
Ptch2, a second mouse patched gene is co-expressed with Sonic hedgehog
-
(1998)
Nat. Genet.
, vol.18
, pp. 104-106
-
-
Motoyama, J.1
-
34
-
-
2042538993
-
Ptc 1 and Ptc2 transcripts provide distinct readouts of hedgehog signalling activity during chick embryogenesis
-
(2001)
Dev. Biol.
, vol.212
, pp. 323-336
-
-
Pearse, R.V.1
-
35
-
-
0030602796
-
The Drosophila Smoothened gene encodes a 7-pass membrane protein, a putative receptor for the hedgehog signal
-
(1996)
Cell
, vol.86
, pp. 221-232
-
-
Alcedo, J.1
-
37
-
-
0009603803
-
Sonic hedgehog signalling by the patched-smoothened receptor complex
-
(1998)
Curr. Biol.
, vol.9
, pp. 76-84
-
-
Murone, M.1
-
39
-
-
0033993990
-
The seven-transmembrane receptor smoothened cell-autonomously induces multiple ventral cell types
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 41-46
-
-
Hynes, M.1
-
41
-
-
0033959532
-
Sonic hedgehog synergizes with the extracellular matrix protein vitronectin, to induce spinal motor neuron differentiation
-
(2000)
Development
, vol.127
, pp. 333-342
-
-
Pons, S.1
Martí, E.2
-
42
-
-
0030795109
-
Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1
-
(1997)
Neuron
, vol.19
, pp. 15-26
-
-
Hynes, M.1
-
43
-
-
0031820135
-
Combinatorial Gli gene function in floor plate and neural inductions by Sonic hedgehog
-
(1998)
Development
, vol.125
, pp. 2203-2212
-
-
Ruiz i Altaba, A.1
-
44
-
-
0031679850
-
Gli 2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system
-
(1998)
Development
, vol.125
, pp. 2754-2770
-
-
Matise, M.P.1
-
45
-
-
0034055649
-
Mouse Gli1 mutants are viable but have defects in SHH signalling in combination with Gli2 mutation
-
(2000)
Development
, vol.127
, pp. 1593-1605
-
-
Park, H.L.1
-
47
-
-
0032808138
-
Gli proteins encode context-dependent positive and negative functions: Implications for development and disease
-
(1999)
Development
, vol.126
, pp. 3205-3216
-
-
Ruiz i Altaba, A.1
-
48
-
-
0032848136
-
Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: Implication of Gli2 and Gli3 as primary mediators of Shh signalling
-
(1999)
Development
, vol.126
, pp. 3915-3924
-
-
Sasaki, H.1
-
49
-
-
0033846864
-
Transcriptional activity of GLI1 is negatively regulated by protein kinase A
-
(2000)
Biol. Chem.
, vol.381
, pp. 545-551
-
-
Kaesler, S.1
-
50
-
-
0029791854
-
Spatial distribution of a zebrafish patched homologue reflects the roles of Sonic hedgehog and protein kinase A in neural tube and somite patterning
-
(1996)
Development
, vol.122
, pp. 2835-2846
-
-
Concordet, J.-P.1
-
51
-
-
0029879687
-
Protein kinase A is a common negative regulator of hedgehog signalling in the vertebrate embryo
-
(1996)
Genes Dev.
, vol.10
, pp. 647-658
-
-
Hammerschmidt, M.1
-
52
-
-
0029821890
-
Antagonizing cAMP-dependent protein kinase A in the dorsal CNS activates a conserved Sonic hedgehog signalling pathway
-
(1996)
Development
, vol.122
, pp. 2885-2894
-
-
Epstein, D.1
-
53
-
-
0033781026
-
Gli regulation by opposing activities of fused and suppressor of fused
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 310-313
-
-
Murone, M.1
-
54
-
-
0033194243
-
Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of GLI-1
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 312-319
-
-
Kogerman, P.1
-
55
-
-
0033566844
-
Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators
-
(1999)
Dev. Biol.
, vol.212
, pp. 323-336
-
-
Pearse, R.V.1
-
56
-
-
0030584081
-
Two critical periods of Sonic hedgehog signalling required for the specification of motor neuron identity
-
(1996)
Cell
, vol.87
, pp. 661-673
-
-
Ericson, J.1
-
57
-
-
0035881919
-
The whereabouts of a morphogen: Direct evidence for short- and graded long-range activity of hedgehog signalling peptides
-
(2001)
Dev. Biol.
, vol.236
, pp. 364-386
-
-
Gritli-Linde, A.1
-
58
-
-
0034964445
-
A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of Sonic hedgehog in the neural tube
-
(2001)
Mol. Cell
, vol.7
, pp. 1279-1291
-
-
Briscoe, J.1
-
59
-
-
0032033034
-
Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development
-
(1998)
Mech. Dev.
, vol.72
, pp. 77-88
-
-
Qiu, M.1
-
60
-
-
0033603209
-
A Sonic hedgehog-independent, retinoid activated pathway of neurogenesis in the ventral spinal cord
-
(1999)
Cell
, vol.97
, pp. 903-915
-
-
Pierani, A.1
-
61
-
-
0034640087
-
A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube
-
(2000)
Cell
, vol.101
, pp. 435-445
-
-
Briscoe, J.1
-
62
-
-
0031458813
-
Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signalling
-
(1997)
Cell
, vol.90
, pp. 169-180
-
-
Ericson, J.1
-
63
-
-
0033560895
-
Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
-
(1999)
Nature
, vol.398
, pp. 622-627
-
-
Briscoe, J.1
-
65
-
-
0034303585
-
Neuronal specification in the spinal cord: Inductive signals and transcriptional codes
-
(2000)
Nat. Genet. Rev.
, vol.1
, pp. 20-29
-
-
Jessell, T.M.1
-
66
-
-
0029127630
-
Induction of midbrain dopaminergic neurons by Sonic hedgehog
-
(1995)
Neuron
, vol.15
, pp. 35-44
-
-
Hynes, M.A.1
-
67
-
-
0029068123
-
Sonic hedgehog induces differentiation of ventral forebrain neurons: A common signal for ventral patterning within the neural tube
-
(1995)
Cell
, vol.81
, pp. 747-756
-
-
Ericson, J.1
-
68
-
-
0032577445
-
FGF and Shh signals control dopaminergic and serotoninergic cell fate in the anterior neural plate
-
(1998)
Cell
, vol.93
, pp. 755-766
-
-
Ye, W.1
-
70
-
-
0032990662
-
Modulation of early but not later stages of programmed cell death in embryonic avian spinal cord by Sonic hedgehog
-
(1999)
Mol. Cell. Neurosci.
, vol.13
, pp. 348-361
-
-
Oppenheim, R.W.1
-
73
-
-
0034981982
-
Monofocal origin of telencephalic oligodendrocytes in the anterior entopeduncular area of the chick embryo
-
(2001)
Development
, vol.128
, pp. 1757-1769
-
-
Oliver, C.1
-
74
-
-
0033767315
-
Sonic hedgehog-regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system
-
(2000)
Neuron
, vol.25
, pp. 317-329
-
-
Lu, Q.1
-
75
-
-
0033746627
-
Dynamic expression of basic helix-loop-helix Olig family members: Implication of Olig2 in neuron and oligodendrocyte differentiation and identification of a new member, Olig3
-
(2000)
Mech. Dev.
, vol.99
, pp. 143-148
-
-
Takebayashi, H.1
-
76
-
-
0033764232
-
Identification of a novel family of oligodendrocyte lineage-specific basic helix-loop-helix transcription factors
-
(2000)
Neuron
, vol.25
, pp. 331-343
-
-
Zhou, Q.1
-
77
-
-
0028928684
-
Oligodendrocytes originate in a restricted zone of the embryonic ventral neural tube defined by DM-20 mRNA expression
-
(1995)
J. Neurosci.
, vol.15
, pp. 1012-1024
-
-
Timsit, S.1
-
78
-
-
0030464161
-
Spinal cord oligodendrocytes develop from ventrally derived progenitor cells that express PDGFα receptors
-
(1996)
Development
, vol.122
, pp. 4085-4094
-
-
Hall, H.1
-
79
-
-
0034650932
-
Single or multiple oligodendroglial lineages: A controversy
-
(2000)
Glia
, vol.29
, pp. 143-148
-
-
Spassky, N.1
-
80
-
-
0035872951
-
Local Sonic hedgehog signalling regulates oligodendrocyte precursor appearance in multiple ventricular zone domains in the chick metencephalon
-
(2001)
Dev. Biol.
, vol.233
, pp. 513-525
-
-
Davies, J.E.1
Miller, R.H.2
-
81
-
-
0029046750
-
Notochord and floorplate stimulate oligodendrocyte differentiation in cultures of the chick dorsal neural tube
-
(1995)
J. Neurosci. Res.
, vol.41
, pp. 552-560
-
-
Trousse, F.1
-
83
-
-
0030292813
-
Induction of oligodendrocyte progenitors in the trunk neural tube by ventralizing signals: Effects of notochord and floor plate grafts, and of Sonic hedgehog
-
(1996)
Mech. Dev.
, vol.60
, pp. 13-32
-
-
Poncet, C.1
-
84
-
-
0030578438
-
Determination of neuroepithelial cells fate: Induction of the oligodendrocyte lineage by ventral midline cells and Sonic hedgehog
-
(1996)
Dev. Biol.
, vol.177
, pp. 30-42
-
-
Pringle, N.P.1
-
85
-
-
2042438039
-
Sonic hedgehog signalling is required during the appearance of spinal cord oligodendrocyte precursors
-
(1999)
Development
, vol.126
, pp. 98-113
-
-
Orentas, D.M.1
-
86
-
-
0035097655
-
Sonic hedgehog contributes to oligodendrocyte specification in the mammalian forebrain
-
(2001)
Development
, vol.128
, pp. 527-540
-
-
Nery, S.1
-
87
-
-
0034928252
-
Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon
-
(2001)
Development
, vol.128
, pp. 2545-2554
-
-
Tekki-Kessaris, N.1
-
88
-
-
0035041063
-
Distinct sites of origin of oligodendrocytes and somatic motorneuons in the chick spinal cord: Oligodendrocytes arise from Nkx2.2-expressing progenitors by a Shh-dependent mechanism
-
(2001)
Development
, vol.128
, pp. 1369-1379
-
-
Soula, C.1
-
89
-
-
0030051923
-
Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation
-
(1996)
Cell
, vol.84
, pp. 309-320
-
-
Pfaff, S.L.1
-
90
-
-
0031761287
-
Pax6 influences the time and site of origin of glial precursors in the ventral neural tube
-
(1998)
Mol. Cell. Neurosci.
, vol.12
, pp. 228-239
-
-
Sun, T.1
-
91
-
-
0034650937
-
Oligodendrocyte lineage and the motor neuron connection
-
(2000)
Glia
, vol.29
, pp. 136-142
-
-
Richardson, W.D.1
-
92
-
-
0035929332
-
Cracking the transcriptional code for cell specification in the neural tube
-
(2001)
Cell
, vol.106
, pp. 651-654
-
-
Marquardt, T.1
Pfaff, S.L.2
-
94
-
-
0032850564
-
Discrete localization of hedgehog signalling components in the developing and adult rat nervous system
-
(1999)
Eur. J. Neurosci.
, vol.11
, pp. 3199-3214
-
-
Traiffort, E.1
-
97
-
-
0033594537
-
Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum
-
(1999)
Curr. Biol.
, vol.9
, pp. 445-448
-
-
Wallace, V.A.1
-
99
-
-
0034993456
-
Vitronectin regulates Sonic hedgehog activity during cerebellum development through CREB phosphorylation
-
(2001)
Development
, vol.128
, pp. 1481-1492
-
-
Pons, S.1
-
100
-
-
0035341310
-
Patched1 interacts with cyclin B1 to regulate cell cycle progression
-
(2001)
EMBO J.
, vol.20
, pp. 2214-2223
-
-
Barnes, E.A.1
-
101
-
-
0033379140
-
Anterior movement of ventral diencephalic precursors separates the primordial eye field in the neural plate and requires cyclops
-
(1999)
Development
, vol.126
, pp. 5533-5546
-
-
Varga, Z.M.1
-
103
-
-
0031043536
-
A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate
-
(1997)
Development
, vol.124
, pp. 603-615
-
-
Li, H.1
-
105
-
-
0028864430
-
Midline signalling is required for Pax gene regulation and patterning of the eyes
-
(1995)
Development
, vol.121
, pp. 3267-3278
-
-
Macdonald, R.1
-
106
-
-
0029347087
-
Patterning activities of vertebrate hedgehog proteins in the developing eye and brain
-
(1995)
Curr. Biol.
, vol.5
, pp. 944-955
-
-
Ekker, S.C.1
-
107
-
-
0033168048
-
Dorsal-ventral patterning defects in the eye of BF-1 deficient mice associated with a restricted loss of Shh expression
-
(1999)
Dev. Biol.
, vol.211
, pp. 53-63
-
-
Huh, S.O.1
-
109
-
-
0031046842
-
Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina
-
(1997)
Development
, vol.124
, pp. 363-371
-
-
Jensen, A.M.1
Wallace, V.2
-
110
-
-
0030797144
-
Sonic hedgehog promotes rod photoreceptor differentiation in mammalian retinal cells in vitro
-
(1997)
J. Neurosci.
, vol.17
, pp. 6277-6288
-
-
Levine, E.M.1
-
112
-
-
0034655684
-
Function for hedgehog genes in zebrafish retinal development
-
(2000)
Dev. Biol.
, vol.220
, pp. 238-252
-
-
Stenkamp, D.L.1
-
113
-
-
0030696920
-
Hedgehog directly controls initiation and propagation of retinal differentiation in the Drosophila eye
-
(1997)
Genes Dev.
, vol.11
, pp. 3254-3264
-
-
Dominguez, M.1
Hafen, E.2
-
115
-
-
0034755395
-
Control of retinal ganglion cell axon growth: A new role for Sonic hedgehog
-
(2001)
Development
, vol.128
, pp. 3927-3936
-
-
Trousse, F.1
-
116
-
-
0029953417
-
Pax2 contributes to inner ear patterning and optic nerve trajectory
-
(1996)
Development
, vol.122
, pp. 3409-3418
-
-
Torres, M.1
-
117
-
-
0030762576
-
The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain
-
(1997)
Development
, vol.124
, pp. 2397-2408
-
-
Macdonald, R.1
-
118
-
-
0035940498
-
Sonic hedgehog restricts integrin-mediated migration of neural crest cells through an alternative patched-independent signalling pathway
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 12521-12526
-
-
Testaz, S.1
-
119
-
-
0035937415
-
Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube
-
(2001)
Cell
, vol.104
, pp. 861-873
-
-
Muhr, J.1
|