p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation

Journal of Cell Science

Volumn 126, Issue 5, 2013, Pages 1144-1154

  Rantanen, Krista ^a,c   Pursiheimo, Juha Pekka ^a,c   Högel, Heidi ^a,c   Miikkulainen, Petra ^a,c   Sundström, Jari ^b   Jaakkola, Panu M ^a,b,c  

^a TURKU CENTRE FOR BIOTECHNOLOGY   (Finland)

^b TURKU UNIVERSITY HOSPITAL   (Finland)

^c ÅBO AKADEMI UNIVERSITY   (Finland)

Author keywords

Aggresome; Autophagy; HIF; Hypoxia; LC 3; LIR domain; NBR1; Prolyl hydroxylase; pVHL; Sequestosome1

Indexed keywords

HYPOXIA INDUCIBLE FACTOR; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEIN P62;

AGGRESOME; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; OXYGEN SENSING; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AUTOPHAGY; DIOXYGENASES; HELA CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; OXYGEN; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84877877932     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.115667     Document Type: Article

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