-
1
-
-
80053517353
-
Drug resistance in human African trypanosomiasis
-
Barrett MP, Vincent IM, Burchmore RJ, Kazibwe AJ, Matovu E. 2011. Drug resistance in human African trypanosomiasis. Future Microbiol. 6:1037-1047.
-
(2011)
Future Microbiol.
, vol.6
, pp. 1037-1047
-
-
Barrett, M.P.1
Vincent, I.M.2
Burchmore, R.J.3
Kazibwe, A.J.4
Matovu, E.5
-
2
-
-
79959790904
-
Development of novel drugs for human African trypanosomiasis
-
Brun R, Don R, Jacobs RT, Wang MZ, Barrett MP. 2011. Development of novel drugs for human African trypanosomiasis. Future Microbiol. 6:677-691.
-
(2011)
Future Microbiol.
, vol.6
, pp. 677-691
-
-
Brun, R.1
Don, R.2
Jacobs, R.T.3
Wang, M.Z.4
Barrett, M.P.5
-
3
-
-
79959787951
-
SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis
-
doi:10.1371/journal.pntd.0001151
-
Jacobs RT, Nare B, Wring SA, Orr MD, Chen D, Sligar JM, Jenks MX, Noe RA, Bowling TS, Mercer LT, Rewerts C, Gaukel E, Owens J, Parham R, Randolph R, Beaudet B, Bacchi CJ, Yarlett N, Plattner JJ, Freund Y, Ding C, Akama T, Zhang YK, Brun R, Kaiser M, Scandale I, Don R. 2011. SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis. PLoS Negl. Trop. Dis. 5:e1151. doi:10.1371/journal.pntd.0001151.
-
(2011)
PLoS Negl. Trop. Dis.
, vol.5
-
-
Jacobs, R.T.1
Nare, B.2
Wring, S.A.3
Orr, M.D.4
Chen, D.5
Sligar, J.M.6
Jenks, M.X.7
Noe, R.A.8
Bowling, T.S.9
Mercer, L.T.10
Rewerts, C.11
Gaukel, E.12
Owens, J.13
Parham, R.14
Randolph, R.15
Beaudet, B.16
Bacchi, C.J.17
Yarlett, N.18
Plattner, J.J.19
Freund, Y.20
Ding, C.21
Akama, T.22
Zhang, Y.K.23
Brun, R.24
Kaiser, M.25
Scandale, I.26
Don, R.27
more..
-
4
-
-
84867337640
-
Antiparasitic agents: New drugs on the horizon
-
Mäser P, Wittlin S, Rottmann M, Wenzler T, Kaiser M, Brun R. 2012. Antiparasitic agents: New drugs on the horizon. Curr. Opin. Pharmacol. 12:562-566.
-
(2012)
Curr. Opin. Pharmacol.
, vol.12
, pp. 562-566
-
-
Mäser, P.1
Wittlin, S.2
Rottmann, M.3
Wenzler, T.4
Kaiser, M.5
Brun, R.6
-
5
-
-
84886541727
-
Application of a resazurin-based high-throughput screening assay for the identification and progression of new treatments for human African trypanosomiasis
-
Bowling T, Mercer L, Don R, Jacobs R, Nare B. 2012. Application of a resazurin-based high-throughput screening assay for the identification and progression of new treatments for human African trypanosomiasis. Int. J. Parasitol. Drugs Drug Resist. 2:262-270.
-
(2012)
Int. J. Parasitol. Drugs Drug Resist.
, vol.2
, pp. 262-270
-
-
Bowling, T.1
Mercer, L.2
Don, R.3
Jacobs, R.4
Nare, B.5
-
6
-
-
0030612893
-
The alamar blue assay to determine drug sensitivity of African trypanosomes (T. b. rhodesiense and T. b. gambiense) in vitro
-
Räz B, Iten M, Grether-Buhler Y, Kaminsky R, Brun R. 1997. The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T. b. rhodesiense and T. b. gambiense) in vitro. Acta Trop. 68:139-147.
-
(1997)
Acta Trop.
, vol.68
, pp. 139-147
-
-
Räz, B.1
Iten, M.2
Grether-Buhler, Y.3
Kaminsky, R.4
Brun, R.5
-
7
-
-
70349755775
-
Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427
-
Sykes ML, Avery VM. 2009. Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427. Am. J. Trop. Med. Hyg. 81:665-674.
-
(2009)
Am. J. Trop. Med. Hyg.
, vol.81
, pp. 665-674
-
-
Sykes, M.L.1
Avery, V.M.2
-
8
-
-
84877845141
-
Present status of the cultivation of African trypanosomes, 165-200
-
In Rowe S, Hirumi H (ed). Schwabe & Co., Basel, Switzerland
-
Hirumi H, Hirumi K, Nelson RT, Bwayo JJ. 1980. Present status of the cultivation of African trypanosomes, p 165-200. In Rowe S, Hirumi H (ed), Tropical diseases research series, vol 3. Schwabe & Co., Basel, Switzerland.
-
(1980)
Tropical Diseases Research Series
, vol.3
-
-
Hirumi, H.1
Hirumi, K.2
Nelson, R.T.3
Bwayo, J.J.4
-
9
-
-
0022410467
-
Cysteine eliminates the feeder cell requirement for cultivation of Trypanosoma brucei bloodstream forms in vitro
-
Duszenko M, Ferguson MA, Lamont GS, Rifkin MR, Cross GA. 1985. Cysteine eliminates the feeder cell requirement for cultivation of Trypanosoma brucei bloodstream forms in vitro. J. Exp. Med. 162:1256-1263.
-
(1985)
J. Exp. Med.
, vol.162
, pp. 1256-1263
-
-
Duszenko, M.1
Ferguson, M.A.2
Lamont, G.S.3
Rifkin, M.R.4
Cross, G.A.5
-
10
-
-
0000146018
-
Cultivation in a semidefined medium of animal infective forms of Trypanosoma brucei
-
T. equiperdum, T. evansi, T. rhodesiense and T. gambiense
-
Baltz T, Baltz D, Giroud C, Crockett J. 1985. Cultivation in a semidefined medium of animal infective forms of Trypanosoma brucei, T. equiperdum, T. evansi, T. rhodesiense and T. gambiense. EMBO J. 4:1273-1277.
-
(1985)
EMBO J.
, vol.4
, pp. 1273-1277
-
-
Baltz, T.1
Baltz, D.2
Giroud, C.3
Crockett, J.4
-
11
-
-
0024948840
-
Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers
-
Hirumi H, Hirumi K. 1989. Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers. J. Parasitol. 75:985-989.
-
(1989)
J. Parasitol.
, vol.75
, pp. 985-989
-
-
Hirumi, H.1
Hirumi, K.2
-
13
-
-
79954416685
-
Advances in mass spectrometry applied to pharmaceutical metabolomics
-
Drexler DM, Reily MD, Shipkova PA. 2011. Advances in mass spectrometry applied to pharmaceutical metabolomics. Anal. Bioanal. Chem. 399: 2645-2653.
-
(2011)
Anal. Bioanal. Chem.
, vol.399
, pp. 2645-2653
-
-
Drexler, D.M.1
Reily, M.D.2
Shipkova, P.A.3
-
14
-
-
74449085466
-
Massspectrometry-based metabolomics: Limitations and recommendations for future progress with particular focus on nutrition research
-
Scalbert A, Brennan L, Fiehn O, Hankemeier T, Kristal B, van Ommen B, Pujos-Guillot E, Verheij E, Wishart D, Wopereis S. 2009. Massspectrometry-based metabolomics: Limitations and recommendations for future progress with particular focus on nutrition research. Metabolomics 5:435-458.
-
(2009)
Metabolomics
, vol.5
, pp. 435-458
-
-
Scalbert, A.1
Brennan, L.2
Fiehn, O.3
Hankemeier, T.4
Kristal, B.5
Van Ommen, B.6
Pujos-Guillot, E.7
Verheij, E.8
Wishart, D.9
Wopereis, S.10
-
15
-
-
84863682324
-
Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma brucei
-
doi:10.1371/journal.pntd.0001618
-
Vincent IM, Creek DJ, Burgess K, Woods DJ, Burchmore RJS, Barrett MP. 2012. Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma brucei. PLoS Negl. Trop. Dis. 6:e1618. doi:10.1371/journal.pntd.0001618.
-
(2012)
PLoS Negl. Trop. Dis.
, vol.6
-
-
Vincent, I.M.1
Creek, D.J.2
Burgess, K.3
Woods, D.J.4
Burchmore, R.J.S.5
Barrett, M.P.6
-
16
-
-
51949118497
-
A domino effect in antifolate drug action in Escherichia coli
-
Kwon YK, Lu W, Melamud E, Khanam N, Bognar A, Rabinowitz JD. 2008. A domino effect in antifolate drug action in Escherichia coli. Nat. Chem. Biol. 4:602-608.
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 602-608
-
-
Kwon, Y.K.1
Lu, W.2
Melamud, E.3
Khanam, N.4
Bognar, A.5
Rabinowitz, J.D.6
-
17
-
-
47249120852
-
Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes
-
Sienkiewicz N, Jaroslawski S, Wyllie S, Fairlamb AH. 2008. Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes. Mol. Microbiol. 69:520-533.
-
(2008)
Mol. Microbiol.
, vol.69
, pp. 520-533
-
-
Sienkiewicz, N.1
Jaroslawski, S.2
Wyllie, S.3
Fairlamb, A.H.4
-
18
-
-
0022401698
-
Nutritional requirements of Plasmodium falciparum in culture. III. Further observations on essential nutrients and antimetabolites
-
Geary TG, Divo AA, Bonanni LC, Jensen JB. 1985. Nutritional requirements of Plasmodium falciparum in culture. III. Further observations on essential nutrients and antimetabolites. J. Eukaryot. Microbiol. 32:608-613.
-
(1985)
J. Eukaryot. Microbiol.
, vol.32
, pp. 608-613
-
-
Geary, T.G.1
Divo, A.A.2
Bonanni, L.C.3
Jensen, J.B.4
-
19
-
-
77954640700
-
Fermentanomics: Monitoring mammalian cell cultures with NMR spectroscopy
-
Bradley SA, Ouyang A, Purdie J, Smitka TA, Wang T, Kaerner A. 2010. Fermentanomics: Monitoring mammalian cell cultures with NMR spectroscopy. J. Am. Chem. Soc. 132:9531-9533.
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 9531-9533
-
-
Bradley, S.A.1
Ouyang, A.2
Purdie, J.3
Smitka, T.A.4
Wang, T.5
Kaerner, A.6
-
20
-
-
79960026499
-
Metabolomics profiling of cell culture media leading to the identification of riboflavin photosensitized degradation of tryptophan causing slow growth in cell culture
-
Zang L, Frenkel R, Simeone J, Lanan M, Byers M, Lyubarskaya Y. 2011. Metabolomics profiling of cell culture media leading to the identification of riboflavin photosensitized degradation of tryptophan causing slow growth in cell culture. Anal. Chem. 83:5422-5430.
-
(2011)
Anal. Chem.
, vol.83
, pp. 5422-5430
-
-
Zang, L.1
Frenkel, R.2
Simeone, J.3
Lanan, M.4
Byers, M.5
Lyubarskaya, Y.6
-
21
-
-
79960978737
-
Isotopomer profiling of Leishmania mexicana promastigotes reveals important roles for succinate fermentation and aspartate uptake in tricarboxylic acid cycle (TCA) anaplerosis, glutamate synthesis, and growth
-
Saunders EC, Ng WW, Chambers JM, Ng M, Naderer T, Kramer JO, Likic VA, McConville MJ. 2011. Isotopomer profiling of Leishmania mexicana promastigotes reveals important roles for succinate fermentation and aspartate uptake in tricarboxylic acid cycle (TCA) anaplerosis, glutamate synthesis, and growth. J. Biol. Chem. 286:27706-27717.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 27706-27717
-
-
Saunders, E.C.1
Ng, W.W.2
Chambers, J.M.3
Ng, M.4
Naderer, T.5
Kramer, J.O.6
Likic, V.A.7
McConville, M.J.8
-
22
-
-
78049351897
-
Towards an unbiased metabolic profiling of protozoan parasites: Optimisation of a Leishmania sampling protocol for HILIC-Orbitrap analysis
-
t'Kindt R, Jankevics A, Scheltema RA, Zheng L, Watson DG, Dujardin JC, Breitling R, Coombs GH, Decuypere S. 2010. Towards an unbiased metabolic profiling of protozoan parasites: Optimisation of a Leishmania sampling protocol for HILIC-Orbitrap analysis. Anal. Bioanal. Chem. 398:2059-2069.
-
(2010)
Anal. Bioanal. Chem.
, vol.398
, pp. 2059-2069
-
-
T'Kindt, R.1
Jankevics, A.2
Scheltema, R.A.3
Zheng, L.4
Watson, D.G.5
Dujardin, J.C.6
Breitling, R.7
Coombs, G.H.8
Decuypere, S.9
-
23
-
-
81255144050
-
Toward global metabolomics analysis with hydrophilic interaction liquid chromatography-mass spectrometry: Improved metabolite identification by retention time prediction
-
Creek DJ, Jankevics A, Breitling R, Watson DG, Barrett MP, Burgess KE. 2011. Toward global metabolomics analysis with hydrophilic interaction liquid chromatography-mass spectrometry: Improved metabolite identification by retention time prediction. Anal. Chem. 83:8703-8710.
-
(2011)
Anal. Chem.
, vol.83
, pp. 8703-8710
-
-
Creek, D.J.1
Jankevics, A.2
Breitling, R.3
Watson, D.G.4
Barrett, M.P.5
Burgess, K.E.6
-
24
-
-
60649089559
-
Highly sensitive feature detection for high resolution LC/MS
-
doi:10.1186/1471-2105-9-504
-
Tautenhahn R, Bottcher C, Neumann S. 2008. Highly sensitive feature detection for high resolution LC/MS. BMC Bioinf. 9:504. doi:10.1186/1471-2105-9- 504.
-
(2008)
BMC Bioinf.
, vol.9
, Issue.504
-
-
Tautenhahn, R.1
Bottcher, C.2
Neumann, S.3
-
25
-
-
79953267955
-
PeakML/mzMatch: A file format, Java library, R library, and tool-chain for mass spectrometry data analysis
-
Scheltema RA, Jankevics A, Jansen RC, Swertz MA, Breitling R. 2011. PeakML/mzMatch: A file format, Java library, R library, and tool-chain for mass spectrometry data analysis. Anal. Chem. 83:2786-2793.
-
(2011)
Anal. Chem.
, vol.83
, pp. 2786-2793
-
-
Scheltema, R.A.1
Jankevics, A.2
Jansen, R.C.3
Swertz, M.A.4
Breitling, R.5
-
26
-
-
84859223223
-
IDEOM: An Excel interface for analysis of LC-MS-based metabolomics data
-
Creek DJ, Jankevics A, Burgess KEV, Breitling R, Barrett MP. 2012. IDEOM: An Excel interface for analysis of LC-MS-based metabolomics data. Bioinformatics 28:1048-1049.
-
(2012)
Bioinformatics
, vol.28
, pp. 1048-1049
-
-
Creek, D.J.1
Jankevics, A.2
Burgess, K.E.V.3
Breitling, R.4
Barrett, M.P.5
-
27
-
-
34748888866
-
Proposed minimum reporting standards for chemical analysis
-
Sumner L, Amberg A, Barrett D, Beale M, Beger R, Daykin C, Fan T, Fiehn O, Goodacre R, Griffin J, Hankemeier T, Hardy N, Harnly J, Higashi R, Kopka J, Lane A, Lindon J, Marriott P, Nicholls A, Reily M, Thaden J, Viant M. 2007. Proposed minimum reporting standards for chemical analysis. Metabolomics 3:211-221.
-
(2007)
Metabolomics
, vol.3
, pp. 211-221
-
-
Sumner, L.1
Amberg, A.2
Barrett, D.3
Beale, M.4
Beger, R.5
Daykin, C.6
Fan, T.7
Fiehn, O.8
Goodacre, R.9
Griffin, J.10
Hankemeier, T.11
Hardy, N.12
Harnly, J.13
Higashi, R.14
Kopka, J.15
Lane, A.16
Lindon, J.17
Marriott, P.18
Nicholls, A.19
Reily, M.20
Thaden, J.21
Viant, M.22
more..
-
28
-
-
4344571581
-
Rank products: A simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments
-
Breitling R, Armengaud P, Amtmann A, Herzyk P. 2004. Rank products: A simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments. FEBS Lett. 573:83-92.
-
(2004)
FEBS Lett.
, vol.573
, pp. 83-92
-
-
Breitling, R.1
Armengaud, P.2
Amtmann, A.3
Herzyk, P.4
-
29
-
-
1442326111
-
MIRACLE: Mass isotopomer ratio analysis of U-13C-labeled extracts. A new method for accurate quantification of changes in concentrations of intracellular metabolites
-
Mashego MR, Wu L, Van Dam JC, Ras C, Vinke JL, Van Winden WA, Van Gulik WM, Heijnen JJ. 2004. MIRACLE: Mass isotopomer ratio analysis of U-13C-labeled extracts. A new method for accurate quantification of changes in concentrations of intracellular metabolites. Biotechnol. Bioeng. 85:620-628.
-
(2004)
Biotechnol. Bioeng.
, vol.85
, pp. 620-628
-
-
Mashego, M.R.1
Wu, L.2
Van Dam, J.C.3
Ras, C.4
Vinke, J.L.5
Van Winden, W.A.6
Van Gulik, W.M.7
Heijnen, J.J.8
-
30
-
-
11144324238
-
Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts as internal standards
-
Wu L, Mashego MR, van Dam JC, Proell AM, Vinke JL, Ras C, van Winden WA, van Gulik WM, Heijnen JJ. 2005. Quantitative analysis of the microbial metabolome by isotope dilution mass spectrometry using uniformly 13C-labeled cell extracts as internal standards. Anal. Biochem. 336:164-171.
-
(2005)
Anal. Biochem.
, vol.336
, pp. 164-171
-
-
Wu, L.1
Mashego, M.R.2
Van Dam, J.C.3
Proell, A.M.4
Vinke, J.L.5
Ras, C.6
Van Winden, W.A.7
Van Gulik, W.M.8
Heijnen, J.J.9
-
31
-
-
42349111860
-
Global metabolic profiling of Escherichia coli cultures: An evaluation of methods for quenching and extraction of intracellular metabolites
-
Winder CL, Dunn WB, Schuler S, Broadhurst D, Jarvis R, Stephens GM, Goodacre R. 2008. Global metabolic profiling of Escherichia coli cultures: An evaluation of methods for quenching and extraction of intracellular metabolites. Anal. Chem. 80:2939-2948.
-
(2008)
Anal. Chem.
, vol.80
, pp. 2939-2948
-
-
Winder, C.L.1
Dunn, W.B.2
Schuler, S.3
Broadhurst, D.4
Jarvis, R.5
Stephens, G.M.6
Goodacre, R.7
-
32
-
-
84863422028
-
Evaluation of coupling reversed phase aqueous normal phase and hydrophilic interaction liquid chromatography with orbitrap mass spectrometry for metabolomic studies of human urine
-
Zhang T, Creek DJ, Barrett MP, Blackburn G, Watson DG. 2012. Evaluation of coupling reversed phase, aqueous normal phase, and hydrophilic interaction liquid chromatography with Orbitrap mass spectrometry for metabolomic studies of human urine. Anal. Chem. 84:1994-2001.
-
(2012)
Anal. Chem.
, vol.84
, pp. 1994-2001
-
-
Zhang, T.1
Creek, D.J.2
Barrett, M.P.3
Blackburn, G.4
Watson, D.G.5
-
33
-
-
84862312013
-
Proliferating bloodstream-form Trypanosoma brucei use a negligible part of consumed glucose for anabolic processes
-
Haanstra JR, van Tuijl A, van Dam J, van Winden W, Tielens AG, van Hellemond JJ, Bakker BM. 2012. Proliferating bloodstream-form Trypanosoma brucei use a negligible part of consumed glucose for anabolic processes. Int. J. Parasitol. 42:667-673.
-
(2012)
Int. J. Parasitol.
, vol.42
, pp. 667-673
-
-
Haanstra, J.R.1
Van Tuijl, A.2
Van Dam, J.3
Van Winden, W.4
Tielens, A.G.5
Van Hellemond, J.J.6
Bakker, B.M.7
-
34
-
-
0026593156
-
Cysteine is an essential growth factor for Trypanosoma brucei bloodstream forms
-
Duszenko M, Mühlstädt K, Broder A. 1992. Cysteine is an essential growth factor for Trypanosoma brucei bloodstream forms. Mol. Biochem. Parasitol. 50:269-273.
-
(1992)
Mol. Biochem. Parasitol.
, vol.50
, pp. 269-273
-
-
Duszenko, M.1
Mühlstädt, K.2
Broder, A.3
-
35
-
-
27644517022
-
Tagging a T. brucei rRNA locus improves stable transfection efficiency and circumvents inducible expression position effects
-
Alsford S, Kawahara T, Glover L, Horn D. 2005. Tagging a T. brucei rRNA locus improves stable transfection efficiency and circumvents inducible expression position effects. Mol. Biochem. Parasitol. 144:142-148.
-
(2005)
Mol. Biochem. Parasitol.
, vol.144
, pp. 142-148
-
-
Alsford, S.1
Kawahara, T.2
Glover, L.3
Horn, D.4
-
36
-
-
58149202163
-
HMDB: A knowledgebase for the human metabolome
-
Wishart DS, Knox C, Guo AC, Eisner R, Young N, Gautam B, Hau DD, Psychogios N, Dong E, Bouatra S, Mandal R, Sinelnikov I, Xia J, Jia L, Cruz JA, Lim E, Sobsey CA, Shrivastava S, Huang P, Liu P, Fang L, Peng J, Fradette R, Cheng D, Tzur D, Clements M, Lewis A, De Souza A, Zuniga A, Dawe M, Xiong Y, Clive D, Greiner R, Nazyrova A, Shaykhutdinov R, Li L, Vogel HJ, Forsythe I. 2009. HMDB: A knowledgebase for the human metabolome. Nucleic Acids Res. 37:D603-D610.
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Wishart, D.S.1
Knox, C.2
Guo, A.C.3
Eisner, R.4
Young, N.5
Gautam, B.6
Hau, D.D.7
Psychogios, N.8
Dong, E.9
Bouatra, S.10
Mandal, R.11
Sinelnikov, I.12
Xia, J.13
Jia, L.14
Cruz, J.A.15
Lim, E.16
Sobsey, C.A.17
Shrivastava, S.18
Huang, P.19
Liu, P.20
Fang, L.21
Peng, J.22
Fradette, R.23
Cheng, D.24
Tzur, D.25
Clements, M.26
Lewis, A.27
De Souza, A.28
Zuniga, A.29
Dawe, M.30
Xiong, Y.31
Clive, D.32
Greiner, R.33
Nazyrova, A.34
Shaykhutdinov, R.35
Li, L.36
Vogel, H.J.37
Forsythe, I.38
more..
-
38
-
-
33751194900
-
Roles for the Trypanosoma brucei P2 transporter in DB75 uptake and resistance
-
Lanteri CA, Stewart ML, Brock JM, Alibu VP, Meshnick SR, Tidwell RR, Barrett MP. 2006. Roles for the Trypanosoma brucei P2 transporter in DB75 uptake and resistance. Mol. Pharmacol. 70:1585-1592.
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 1585-1592
-
-
Lanteri, C.A.1
Stewart, M.L.2
Brock, J.M.3
Alibu, V.P.4
Meshnick, S.R.5
Tidwell, R.R.6
Barrett, M.P.7
-
39
-
-
2142660741
-
The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: Additional insights on diamidine resistance in African trypanosomes
-
de Koning HP, Anderson LF, Stewart M, Burchmore RJ, Wallace LJ, Barrett MP. 2004. The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: Additional insights on diamidine resistance in African trypanosomes. Antimicrob. Agents Chemother. 48:1515-1519.
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, pp. 1515-1519
-
-
De Koning, H.P.1
Anderson, L.F.2
Stewart, M.3
Burchmore, R.J.4
Wallace, L.J.5
Barrett, M.P.6
-
40
-
-
79955549900
-
Trypanocidal furamidine analogues: Influence of pyridine nitrogens on trypanocidal activity, transport kinetics, and resistance patterns
-
Ward CP, Wong PE, Burchmore RJ, de Koning HP, Barrett MP. 2011. Trypanocidal furamidine analogues: Influence of pyridine nitrogens on trypanocidal activity, transport kinetics, and resistance patterns. Antimicrob. Agents Chemother. 55:2352-2361.
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 2352-2361
-
-
Ward, C.P.1
Wong, P.E.2
Burchmore, R.J.3
De Koning, H.P.4
Barrett, M.P.5
-
41
-
-
84859440745
-
The de novo and salvage pathways of GDP-mannose biosynthesis are both sufficient for the growth of bloodstream-form Trypanosoma brucei
-
Kuettel S, Wadum MC, Güther ML, Mariño K, Riemer C, Ferguson MA. 2012. The de novo and salvage pathways of GDP-mannose biosynthesis are both sufficient for the growth of bloodstream-form Trypanosoma brucei. Mol. Microbiol. 84:340-351.
-
(2012)
Mol. Microbiol.
, vol.84
, pp. 340-351
-
-
Kuettel, S.1
Wadum, M.C.2
Güther, M.L.3
Mariño, K.4
Riemer, C.5
Ferguson, M.A.6
-
42
-
-
0031083414
-
Cultivation of bloodstream forms of Trypanosoma brucei and T. evansi in a serum-free medium
-
Hirumi H, Martin S, Hirumi K, Inoue N, Kanbara H, Saito A, Suzuki N. 1997. Cultivation of bloodstream forms of Trypanosoma brucei and T. evansi in a serum-free medium. Trop. Med. Int. Health 2:240-244.
-
(1997)
Trop. Med. Int. Health
, vol.2
, pp. 240-244
-
-
Hirumi, H.1
Martin, S.2
Hirumi, K.3
Inoue, N.4
Kanbara, H.5
Saito, A.6
Suzuki, N.7
-
43
-
-
43149097159
-
Global metabolic responses of mice to Trypanosoma brucei brucei infection
-
Wang Y, Utzinger J, Saric J, Li JV, Burckhardt J, Dirnhofer S, Nicholson JK, Singer BH, Brun R, Holmes E. 2008. Global metabolic responses of mice to Trypanosoma brucei brucei infection. Proc. Natl. Acad. Sci. U. S. A. 105:6127-6132.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 6127-6132
-
-
Wang, Y.1
Utzinger, J.2
Saric, J.3
Li, J.V.4
Burckhardt, J.5
Dirnhofer, S.6
Nicholson, J.K.7
Singer, B.H.8
Brun, R.9
Holmes, E.10
-
44
-
-
0023492718
-
Further biochemical characterization of chronic Trypanosoma brucei gambiense-Microtus montanus infection
-
Seed JR, Sechelski J, Hall JE. 1987. Further biochemical characterization of chronic Trypanosoma brucei gambiense-Microtus montanus infection. Am. J. Trop. Med. Hyg. 37:314-319.
-
(1987)
Am. J. Trop. Med. Hyg.
, vol.37
, pp. 314-319
-
-
Seed, J.R.1
Sechelski, J.2
Hall, J.E.3
-
45
-
-
9244221583
-
Aromatic amino acid transamination and methionine recycling in trypanosomatids
-
Berger BJ, Dai WW, Wang H, Stark RE, Cerami A. 1996. Aromatic amino acid transamination and methionine recycling in trypanosomatids. Proc. Natl. Acad. Sci. U. S. A. 93:4126-4130.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 4126-4130
-
-
Berger, B.J.1
Dai, W.W.2
Wang, H.3
Stark, R.E.4
Cerami, A.5
-
46
-
-
0034494342
-
Transport of methionine in Trypanosoma brucei brucei
-
Hasne MP, Barrett MP. 2000. Transport of methionine in Trypanosoma brucei brucei. Mol. Biochem. Parasitol. 111:299-307.
-
(2000)
Mol. Biochem. Parasitol.
, vol.111
, pp. 299-307
-
-
Hasne, M.P.1
Barrett, M.P.2
-
48
-
-
78049341926
-
Simple data-reduction method for high-resolution LCMS data in metabolomics
-
Scheltema R, Decuypere S, Dujardin J, Watson D, Jansen R, Breitling R. 2009. Simple data-reduction method for high-resolution LCMS data in metabolomics. Bioanalysis 1:1551-1557.
-
(2009)
Bioanalysis
, vol.1
, pp. 1551-1557
-
-
Scheltema, R.1
Decuypere, S.2
Dujardin, J.3
Watson, D.4
Jansen, R.5
Breitling, R.6
-
49
-
-
0022454288
-
Characterization of Trypanosoma brucei brucei S-adenosyl-L-methionine decarboxylase and its inhibition by Berenil, pentamidine and methylglyoxal bis(guanylhydrazone)
-
Bitonti AJ, Dumont JA, McCann PP. 1986. Characterization of Trypanosoma brucei brucei S-adenosyl-L-methionine decarboxylase and its inhibition by Berenil, pentamidine and methylglyoxal bis(guanylhydrazone). Biochem. J. 237:685-689.
-
(1986)
Biochem. J.
, vol.237
, pp. 685-689
-
-
Bitonti, A.J.1
Dumont, J.A.2
McCann, P.P.3
-
50
-
-
0027436769
-
Polyamine and pentamidine metabolism in African trypanosomes
-
Berger BJ, Carter NS, Fairlamb AH. 1993. Polyamine and pentamidine metabolism in African trypanosomes. Acta Trop. 54:215-224.
-
(1993)
Acta Trop.
, vol.54
, pp. 215-224
-
-
Berger, B.J.1
Carter, N.S.2
Fairlamb, A.H.3
-
51
-
-
84856955769
-
High-throughput decoding of antitrypanosomal drug efficacy and resistance
-
Alsford S, Eckert S, Baker N, Glover L, Sanchez-Flores A, Leung KF, Turner DJ, Field MC, Berriman M, Horn D. 2012. High-throughput decoding of antitrypanosomal drug efficacy and resistance. Nature 482: 232-236.
-
(2012)
Nature
, vol.482
, pp. 232-236
-
-
Alsford, S.1
Eckert, S.2
Baker, N.3
Glover, L.4
Sanchez-Flores, A.5
Leung, K.F.6
Turner, D.J.7
Field, M.C.8
Berriman, M.9
Horn, D.10
-
52
-
-
45849096432
-
Antiparasitic compounds that target DNA
-
Wilson WD, Tanious FA, Mathis A, Tevis D, Hall JE, Boykin DW. 2008. Antiparasitic compounds that target DNA. Biochimie 90:999-1014.
-
(2008)
Biochimie
, vol.90
, pp. 999-1014
-
-
Wilson, W.D.1
Tanious, F.A.2
Mathis, A.3
Tevis, D.4
Hall, J.E.5
Boykin, D.W.6
-
53
-
-
40549136475
-
The mitochondrion is a site of trypanocidal action of the aromatic diamidine DB75 in bloodstream forms of Trypanosoma brucei
-
Lanteri CA, Tidwell RR, Meshnick SR. 2008. The mitochondrion is a site of trypanocidal action of the aromatic diamidine DB75 in bloodstream forms of Trypanosoma brucei. Antimicrob. Agents Chemother. 52:875-882.
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 875-882
-
-
Lanteri, C.A.1
Tidwell, R.R.2
Meshnick, S.R.3
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