Introduction of a lysine residue promotes aggregation of temporin L in lipopolysaccharides and augmentation of its antiendotoxin property

Antimicrobial Agents and Chemotherapy

Volumn 57, Issue 6, 2013, Pages 2457-2466

  Srivastava, Saurabh ^a   Ghosh, Jimut Kanti ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GLUTAMINE; INTERLEUKIN 6; LYSINE; POLYPEPTIDE ANTIBIOTIC AGENT; TEMPORIN L; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALGORITHM; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BACTERICIDAL ACTIVITY; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DRUG BINDING; DRUG CYTOTOXICITY; DRUG DETOXIFICATION; DRUG EFFICACY; FEMALE; HEMOLYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MOUSE; NONHUMAN; OLIGOMERIZATION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT;

AMINO ACID SUBSTITUTION; ANIMALS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CELLS, CULTURED; CYTOKINES; ENDOTOXINS; FEMALE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INFLAMMATION; L CELLS (CELL LINE); LIPOPOLYSACCHARIDES; LYSINE; MACROPHAGES; MICE; MICE, INBRED BALB C; PROTEINS; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84877862561     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00169-13     Document Type: Article

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