Formaldehyde induces hyperphosphorylation and polymerization of Tau protein both in vitro and in vivo

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 8, 2013, Pages 4102-4116

  Lu, Jing ^a,c,d   Miao, Junye ^a,c   Su, Tao ^a,c   Liu, Ying ^a   He, Rongqiao ^a,b  

^a INSTITUTE OF BIOPHYSICS   (China)

^b INSTITUTE OF PSYCHOLOGY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Formaldehyde; GSK 3 ; Nuclear accumulation; Protein polymerization; Tau hyperphosphorylation; Tauopathy

Indexed keywords

FORMALDEHYDE; GLYCOGEN SYNTHASE KINASE 3BETA; POLYMER; TAU PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BRAIN CELL; CELL NUCLEUS; CELL STRAIN; CELL STRAIN N2A; CELL STRESS; CONTROLLED STUDY; CYTOPLASM; ENZYME INHIBITION; ENZYME LOCALIZATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN POLYMERIZATION;

ANIMALS; CELL LINE, TUMOR; FORMALDEHYDE; GLYCOGEN SYNTHASE KINASE 3; MICE; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; TAU PROTEINS;

MUS;

EID: 84877841177     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.04.028     Document Type: Article

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