Trimming of damaged 3' overhangs of DNA double-strand breaks by the Metnase and Artemis endonucleases

DNA Repair

Volumn 12, Issue 6, 2013, Pages 422-432

  Mohapatra, Susovan ^a,f   Yannone, Steven M ^b   Lee, Suk Hee ^c   Hromas, Robert A ^d   Akopiants, Konstantin ^a   Menon, Vijay ^a   Ramsden, Dale A ^e   Povirk, Lawrence F ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^f Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Clustered DNA damage; Free radicals; Nonhomologous end joining; Oxidative damage

Indexed keywords

ARTEMIS; DNA DEPENDENT PROTEIN KINASE; DOUBLE STRANDED DNA; ENDONUCLEASE; METNASE; PROTEIN DERIVATIVE; THYMINE DNA GLYCOSYLASE; UNCLASSIFIED DRUG;

ARTICLE; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

DNA ADDUCTS; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA LIGASES; DNA REPAIR ENZYMES; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; GLYCOLATES; HEK293 CELLS; HELA CELLS; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; NUCLEAR PROTEINS; RECOMBINATIONAL DNA REPAIR; THYMINE;

EID: 84877833979     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2013.03.005     Document Type: Article

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