Insulin-loaded poly(ε-caprolactone) nanoparticles: Efficient, sustained and safe insulin delivery system

Journal of Biomedical Nanotechnology

Volumn 9, Issue 6, 2013, Pages 1098-1106

  De Araújo, Thiago M ^a   Teixeira, Zaine ^a,b   Barbosa Sampaio, Helena C ^a   Rezende, Luiz F ^a   Boschero, Antonio C ^a   Durán, Nelson ^a   Höehr, Nelci F ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

Author keywords

Cytotoxicity; Diabetes; Hepatotoxicity; Insulin; Polymeric nanoparticles; Sustained release

Indexed keywords

AVERAGE PARTICLE SIZE; CONTROLLED RELEASE SYSTEMS; ENCAPSULATION EFFICIENCY; HEPATOTOXICITY; INSULIN DELIVERY SYSTEM; POLYMERIC NANOPARTICLES; SUSTAINED RELEASE; WATER-IN-OIL-IN-WATER;

CYTOTOXICITY; EMULSIFICATION; EMULSIONS; ENCAPSULATION; MEDICAL PROBLEMS; NANOPARTICLES; RATS; ZETA POTENTIAL;

INSULIN;

BIOMATERIAL; GLUCOSE; INSULIN; NANOPARTICLE; POLOXAMER; POLYCAPROLACTONE; WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; CELL DEATH; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; EMULSION; ENCAPSULATION; GLUCOSE BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; LIVER CELL; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PARTICLE SIZE; RAT; ZETA POTENTIAL;

ANIMALS; DELAYED-ACTION PREPARATIONS; DIABETES MELLITUS, EXPERIMENTAL; DIFFUSION; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MATERIALS TESTING; NANOCAPSULES; POLYESTERS; RATS; RATS, WISTAR; STREPTOZOCIN;

EID: 84877809007     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2013.1607     Document Type: Article

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