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Volumn 125, Issue 3, 2007, Pages 275-296

New frontiers in the management of type 2 diabetes

Author keywords

Glucose lowering agents; Non invasive therapy; Recent advances; Treatment; Type 2 diabetes

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ACETYLSALICYLIC ACID; ALBUGON; ANTIDIABETIC AGENT; AT 1391; CJC 1131; EXENDIN 4; FIBRIC ACID DERIVATIVE; GASTROINTESTINAL HORMONE; GLIMEPIRIDE; GLUCOSE; HUMAN INSULIN; INSULIN; INSULIN GLARGINE; INSULIN LISPRO; INSULIN SENSITIZING AGENT; ISOPHANE INSULIN; LIRAGLUTIDE; MEGLITINIDE; METFORMIN; MURAGLITAZAR; ORAL ANTIDIABETIC AGENT; PIOGLITAZONE; PLACEBO; PRAMLINTIDE; PROPELLANT; RECOMBINANT HUMAN INSULIN; ROSIGLITAZONE; SITAGLIPTIN; SULFONYLUREA DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VILDAGLIPTIN;

EID: 34249288293     PISSN: 09715916     EISSN: 09715916     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (12)

References (97)
  • 1
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
    • Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004; 27: 1047-53.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 2
    • 34249332521 scopus 로고    scopus 로고
    • Harris MI. Summary. In: Harris MI, Courie CC, Stern MP, Boyko EJ, Reiber GE, Bennet PH, editors. Diabetes in America, 2nd ed. Washington, DC: US Department of Health and Human Services, National Institute of Health, DHHS publication no.(NIH) 95-1468; 1995.
    • Harris MI. Summary. In: Harris MI, Courie CC, Stern MP, Boyko EJ, Reiber GE, Bennet PH, editors. Diabetes in America, 2nd ed. Washington, DC: US Department of Health and Human Services, National Institute of Health, DHHS publication no.(NIH) 95-1468; 1995.
  • 3
    • 0024026298 scopus 로고
    • Lilly, Lecture 1987: The triumvirate: beta cell, muscle, liver. A collusion responsible for NIDDM
    • DeFronzo RA: Lilly, Lecture 1987: The triumvirate: beta cell, muscle, liver. A collusion responsible for NIDDM. Diabetes 1988, 37: 667-87.
    • (1988) Diabetes , vol.37 , pp. 667-687
    • DeFronzo, R.A.1
  • 4
    • 0034884627 scopus 로고    scopus 로고
    • The role of impaired early insulin secretion in the pathogenesis of Type II diabetes mellitus
    • Pratley RE. Weyer C: The role of impaired early insulin secretion in the pathogenesis of Type II diabetes mellitus. Diabetologia 2001; 44: 929-45.
    • (2001) Diabetologia , vol.44 , pp. 929-945
    • Pratley, R.E.1    Weyer, C.2
  • 5
    • 0035897696 scopus 로고    scopus 로고
    • Evaluation, And Treatment of High Blood Cholesterol in Adults: Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection
    • Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol in Adults: Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001; 285: 2486-97.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 6
    • 0032490706 scopus 로고    scopus 로고
    • The cardiovascular dysmetabolic syndrome
    • Fagan TC, Deedwania PC. The cardiovascular dysmetabolic syndrome. Am J Med 1998; 105: 77S-82.
    • (1998) Am J Med , vol.105
    • Fagan, T.C.1    Deedwania, P.C.2
  • 7
    • 34249307031 scopus 로고    scopus 로고
    • accessed March 13, 2006
    • http://www.idf.org/home/index.cfm (accessed March 13, 2006).
  • 8
    • 32144448938 scopus 로고    scopus 로고
    • Standards of Medical Care in Diabetes - 2006 American Diabetes Association. Diabetes Care 2006; 29: S4-42.
    • Standards of Medical Care in Diabetes - 2006 American Diabetes Association. Diabetes Care 2006; 29: S4-42.
  • 9
    • 0037116638 scopus 로고    scopus 로고
    • Oral antihyperglycemic therapy for type 2 diabetes: Scientific review
    • Inzucchi SE. Oral antihyperglycemic therapy for type 2 diabetes: scientific review. JAMA 2002; 287: 360-72.
    • (2002) JAMA , vol.287 , pp. 360-372
    • Inzucchi, S.E.1
  • 10
    • 0034819464 scopus 로고    scopus 로고
    • Combination therapies with insulin in type 2 diabetes
    • Yki-Järvinen H. Combination therapies with insulin in type 2 diabetes. Diabetes Care 2001; 24: 758-67.
    • (2001) Diabetes Care , vol.24 , pp. 758-767
    • Yki-Järvinen, H.1
  • 11
    • 0347133334 scopus 로고    scopus 로고
    • Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes
    • Saydah SH, Fradkin J, Cowie CC. Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. JAMA 2004; 291: 335-42.
    • (2004) JAMA , vol.291 , pp. 335-342
    • Saydah, S.H.1    Fradkin, J.2    Cowie, C.C.3
  • 12
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulfonylurea or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study Group
    • UK Prospective Diabetes Study Group. Intensive blood-glucose control with sulfonylurea or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998; 352: 837-53.
    • (1998) Lancet , vol.352 , pp. 837-853
  • 13
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
    • UK Prospective Diabetes Study Group
    • UK Prospective Diabetes Study Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 1998; 352: 854-65.
    • (1998) Lancet , vol.352 , pp. 854-865
  • 14
    • 0037031061 scopus 로고    scopus 로고
    • Heart Protection Study Collaborative Group MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 2002; 360: 7-22
    • Heart Protection Study Collaborative Group MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 2002; 360: 7-22.
  • 15
    • 0032511580 scopus 로고    scopus 로고
    • Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38
    • UK Prospective Diabetes Study Group
    • UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 1998; 317: 703-13.
    • (1998) BMJ , vol.317 , pp. 703-713
  • 16
    • 0032513878 scopus 로고    scopus 로고
    • Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: Principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group
    • Hansson L, Zanchetti A, Carruthers SG, Dahlof B, Elmfeldt D, Julius S, et al. Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group. Lancet 1998; 351: 1755-62.
    • (1998) Lancet , vol.351 , pp. 1755-1762
    • Hansson, L.1    Zanchetti, A.2    Carruthers, S.G.3    Dahlof, B.4    Elmfeldt, D.5    Julius, S.6
  • 17
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with life style intervention or metformin
    • Diabetes Prevention Program Research Group
    • Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with life style intervention or metformin. N Engl J Med 2002; 346: 393-403.
    • (2002) N Engl J Med , vol.346 , pp. 393-403
  • 19
    • 0032560807 scopus 로고    scopus 로고
    • Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
    • Haffner SM, Lehto S, Ronnemaa T, Pyorala K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med 1998; 339: 229-34.
    • (1998) N Engl J Med , vol.339 , pp. 229-234
    • Haffner, S.M.1    Lehto, S.2    Ronnemaa, T.3    Pyorala, K.4    Laakso, M.5
  • 20
    • 0035832558 scopus 로고    scopus 로고
    • Excess mortality in a population with diabetes and the impact of material deprivation: Longitudinal, population based study
    • Roper NA, Bilous RW, Kelly WF, Unwin NC, Connolly VM. Excess mortality in a population with diabetes and the impact of material deprivation: longitudinal, population based study. BMJ 2001; 322: 1389-93.
    • (2001) BMJ , vol.322 , pp. 1389-1393
    • Roper, N.A.1    Bilous, R.W.2    Kelly, W.F.3    Unwin, N.C.4    Connolly, V.M.5
  • 21
    • 0036705874 scopus 로고    scopus 로고
    • PPAR agonists in health and disease: A pathophysiologic and clinical overview
    • Mudaliar S, Henry RR. PPAR agonists in health and disease: a pathophysiologic and clinical overview. Curr Opin Endocrinol Diabetes 2002; 9: 285-302.
    • (2002) Curr Opin Endocrinol Diabetes , vol.9 , pp. 285-302
    • Mudaliar, S.1    Henry, R.R.2
  • 23
    • 26244453309 scopus 로고    scopus 로고
    • The PROactive investigators. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive,Study (PROspective pioglitAzone Clinical Trial In macro Vascular Events): A randomised controlled trial
    • Dormandy JA, Charbonnel B, Eckland DJ, Erdmann E, Massi-Bennedetti M, Moules IK, et al. The PROactive investigators. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive,Study (PROspective pioglitAzone Clinical Trial In macro Vascular Events): a randomised controlled trial. Lancet 2005; 366: 1279-89.
    • (2005) Lancet , vol.366 , pp. 1279-1289
    • Dormandy, J.A.1    Charbonnel, B.2    Eckland, D.J.3    Erdmann, E.4    Massi-Bennedetti, M.5    Moules, I.K.6
  • 25
    • 33644645475 scopus 로고    scopus 로고
    • Commentary on the Results and Clinical Implications of the PROactive Study
    • Rizza R, Henry R, Kahn R. Commentary on the Results and Clinical Implications of the PROactive Study. Diabetes Care 2005; 28: 2965-7.
    • (2005) Diabetes Care , vol.28 , pp. 2965-2967
    • Rizza, R.1    Henry, R.2    Kahn, R.3
  • 26
    • 34249299531 scopus 로고    scopus 로고
    • accessed on March 13, 2006
    • http://www.nih.gov/news/pr/feb2003/nhlbi-20.htm, accessed on March 13, 2006.
  • 27
    • 24944569269 scopus 로고    scopus 로고
    • Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes (RECORD): Study design and protocol
    • Home PD, Pocock SJ, Beck-Nielsen H, Gomis R, Hanefeld M, Dargie H, et al. Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes (RECORD): study design and protocol. Diabetologia 2005; 48: 1726-35.
    • (2005) Diabetologia , vol.48 , pp. 1726-1735
    • Home, P.D.1    Pocock, S.J.2    Beck-Nielsen, H.3    Gomis, R.4    Hanefeld, M.5    Dargie, H.6
  • 28
    • 28144451163 scopus 로고    scopus 로고
    • Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus
    • Nissen SE, Wolski K, Topol EJ. Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus. JAMA 2005; 294: 2581-6.
    • (2005) JAMA , vol.294 , pp. 2581-2586
    • Nissen, S.E.1    Wolski, K.2    Topol, E.J.3
  • 29
    • 33646353949 scopus 로고    scopus 로고
    • Emerging therapies mimicking the effects of amylin and glucagon-like peptide 1
    • Riddle MC, Drucker DJ. Emerging therapies mimicking the effects of amylin and glucagon-like peptide 1. Diabetes Care 2006; 29: 435-49.
    • (2006) Diabetes Care , vol.29 , pp. 435-449
    • Riddle, M.C.1    Drucker, D.J.2
  • 30
    • 23944484014 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 as a treatment option for type 2 diabetes and its role in restoring beta-cell mass
    • Gallwitz B. Glucagon-like peptide-1 as a treatment option for type 2 diabetes and its role in restoring beta-cell mass. Diabetes Technol Ther 2005; 7: 651-7.
    • (2005) Diabetes Technol Ther , vol.7 , pp. 651-657
    • Gallwitz, B.1
  • 31
    • 15044362439 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 and its derivatives in the treatment of diabetes
    • Nauck MA, Meier JJ. Glucagon-like peptide 1 and its derivatives in the treatment of diabetes. Regulatory Peptides 2005; 128: 135-48.
    • (2005) Regulatory Peptides , vol.128 , pp. 135-148
    • Nauck, M.A.1    Meier, J.J.2
  • 32
    • 1842421982 scopus 로고    scopus 로고
    • Emerging therapies: Controlling glucose homeostasis, immunotherapy, islet transplantation, gene therapy, and islet cell neogenesis and regeneration
    • Ruggles JA. Kelemen D. Baron A. Emerging therapies: controlling glucose homeostasis, immunotherapy, islet transplantation, gene therapy, and islet cell neogenesis and regeneration. Endocrinol Metab Clin North Am 2004; 33: 239-52.
    • (2004) Endocrinol Metab Clin North Am , vol.33 , pp. 239-252
    • Ruggles, J.A.1    Kelemen, D.2    Baron, A.3
  • 33
    • 18144401971 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
    • Defronzo RA, Ratner RE, Han J, Kim DD, Fineman MS, Baron AD. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care 2005; 28: 1092-100.
    • (2005) Diabetes Care , vol.28 , pp. 1092-1100
    • Defronzo, R.A.1    Ratner, R.E.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5    Baron, A.D.6
  • 34
    • 17144371646 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
    • Kendall DM, Riddle MC, Rosenstock J, Zhuang D, Kim DD, Finemann MS, et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea. Diabetes Care 2005; 28: 1083-91.
    • (2005) Diabetes Care , vol.28 , pp. 1083-1091
    • Kendall, D.M.1    Riddle, M.C.2    Rosenstock, J.3    Zhuang, D.4    Kim, D.D.5    Finemann, M.S.6
  • 35
    • 7444228521 scopus 로고    scopus 로고
    • Effects of exenatide (Exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
    • for the Exenatide-113 Clinical Study Group
    • Buse JB, Henry RR, Han J, Kim DD, Fineman MS, Baron AD for the Exenatide-113 Clinical Study Group. Effects of exenatide (Exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 2004; 27: 2628-635.
    • (2004) Diabetes Care , vol.27 , pp. 2628-2635
    • Buse, J.B.1    Henry, R.R.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5    Baron, A.D.6
  • 36
    • 34249306676 scopus 로고    scopus 로고
    • accessed March 13, 2006
    • http://www.amylin.com/pipeline/exenatidelar.cfm (accessed March 13, 2006).
  • 37
    • 2542451393 scopus 로고    scopus 로고
    • NN2211-1340 International Study Group. Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): A 12-week, double-blind, randomized, controlled trial
    • Madsbad S, Schmitz O, Ranstam J, Jakobsen G, Matthews DR; NN2211-1340 International Study Group. Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial. Diabetes Care 2004; 27: 1335-42.
    • (2004) Diabetes Care , vol.27 , pp. 1335-1342
    • Madsbad, S.1    Schmitz, O.2    Ranstam, J.3    Jakobsen, G.4    Matthews, D.R.5
  • 38
    • 22644444292 scopus 로고    scopus 로고
    • Liraglutide dose Response Study Group. Effects of liraglutide (NN2211), a long acting GLP-1 analogue, on glycaemic control and body weight in subjects with type 2 diabetes
    • Feinglos MN, Saad MF, Pi-Sunyer FX, An B, Santiago O; Liraglutide dose Response Study Group. Effects of liraglutide (NN2211), a long acting GLP-1 analogue, on glycaemic control and body weight in subjects with type 2 diabetes. Diabet Med 2005; 22: 1016-23.
    • (2005) Diabet Med , vol.22 , pp. 1016-1023
    • Feinglos, M.N.1    Saad, M.F.2    Pi-Sunyer, F.X.3    An, B.4    Santiago, O.5
  • 39
    • 2642519637 scopus 로고    scopus 로고
    • Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors
    • Holst JJ. Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors. Expert Opin Emerg Drugs 2004; 9: 155-66.
    • (2004) Expert Opin Emerg Drugs , vol.9 , pp. 155-166
    • Holst, J.J.1
  • 40
    • 9444285818 scopus 로고    scopus 로고
    • Twelve-and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes
    • Ahren B, Gomis R, Standl E, Mills D, Schweizer A. Twelve-and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes. Diabetes Care 2004; 27: 2874-80.
    • (2004) Diabetes Care , vol.27 , pp. 2874-2880
    • Ahren, B.1    Gomis, R.2    Standl, E.3    Mills, D.4    Schweizer, A.5
  • 41
    • 23044487247 scopus 로고    scopus 로고
    • Improved meal-related beta-cell function and insulin sensitivity by the dipeptidyl peptidase-IV inhibitor vildagliptin in metformintreated patients with type 2 diabetes over 1 year
    • Ahren B, Pacini G, Foley JE, Schweizer A. Improved meal-related beta-cell function and insulin sensitivity by the dipeptidyl peptidase-IV inhibitor vildagliptin in metformintreated patients with type 2 diabetes over 1 year. Diabetes Care 2005; 28: 1936-40.
    • (2005) Diabetes Care , vol.28 , pp. 1936-1940
    • Ahren, B.1    Pacini, G.2    Foley, J.E.3    Schweizer, A.4
  • 42
    • 28844482322 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: Results from two randomized, double-blind, placebo-controlled studies with single oral doses
    • Bergman AJ, Stevens C, Zhou Y, Yi B, Laethem M, De Smet M, et al. Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind, placebo-controlled studies with single oral doses. Clin Pharmacol Ther 2005; 78: 675-88.
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 675-688
    • Bergman, A.J.1    Stevens, C.2    Zhou, Y.3    Yi, B.4    Laethem, M.5    De Smet, M.6
  • 43
    • 9444257636 scopus 로고    scopus 로고
    • Amylin agonists: A novel approach in the treatment of diabetes
    • Schmitz O, Brock B, Rungby J. Amylin agonists: a novel approach in the treatment of diabetes. Diabetes 2004; 53 (Suppl 3): S233-8.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 3
    • Schmitz, O.1    Brock, B.2    Rungby, J.3
  • 44
    • 0000184757 scopus 로고    scopus 로고
    • Amylin's physiology and its role in diabetes
    • Young AA. Amylin's physiology and its role in diabetes. Carr Opin Endocrinol Diabetes 1997; 4: 282-90.
    • (1997) Carr Opin Endocrinol Diabetes , vol.4 , pp. 282-290
    • Young, A.A.1
  • 45
    • 3242752688 scopus 로고    scopus 로고
    • Pramlintide for the treatment of insulin-requiring diabetes mellitus: Rationale and review of clinical data
    • Kruger DF, Gloster MA. Pramlintide for the treatment of insulin-requiring diabetes mellitus: rationale and review of clinical data. Drugs 2004; 64: 1419-32.
    • (2004) Drugs , vol.64 , pp. 1419-1432
    • Kruger, D.F.1    Gloster, M.A.2
  • 46
    • 0042167233 scopus 로고    scopus 로고
    • Pramlintide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: A 1-year randomized controlled trial
    • Hollander PA, Levy P, Fineman MS, Maggs DG, Shen LZ, Strobel SA, et al. Pramlintide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: a 1-year randomized controlled trial. Diabetes Care 2003; 26: 784-90.
    • (2003) Diabetes Care , vol.26 , pp. 784-790
    • Hollander, P.A.1    Levy, P.2    Fineman, M.S.3    Maggs, D.G.4    Shen, L.Z.5    Strobel, S.A.6
  • 47
    • 26944435504 scopus 로고    scopus 로고
    • Inhaled insulin improves glycemic control when substituted for or added to oral combination therapy in type 2 diabetes: A randomized, controlled trial
    • Rosenstock J, Zinman B, Murphy LJ, Clement SC, Moore P, Bowering CK, et al. Inhaled insulin improves glycemic control when substituted for or added to oral combination therapy in type 2 diabetes: a randomized, controlled trial. Ann Intern Med 2005; 143: 549-58.
    • (2005) Ann Intern Med , vol.143 , pp. 549-558
    • Rosenstock, J.1    Zinman, B.2    Murphy, L.J.3    Clement, S.C.4    Moore, P.5    Bowering, C.K.6
  • 48
    • 0034851705 scopus 로고    scopus 로고
    • Phobia of self-injecting and self-testing in insulin-treated diabetes patients: Opportunities for screening
    • Mollema ED, Snoek FJ, Heine RJ, van der Ploeg HM. Phobia of self-injecting and self-testing in insulin-treated diabetes patients: opportunities for screening. Diabet Med 2001; 18: 671-4.
    • (2001) Diabet Med , vol.18 , pp. 671-674
    • Mollema, E.D.1    Snoek, F.J.2    Heine, R.J.3    van der Ploeg, H.M.4
  • 50
    • 18144368866 scopus 로고    scopus 로고
    • Time-action profile of inhaled insulin in comparison with subcutaneously injected insulin lispro and regular human insulin
    • Rave K, Bott S, Heinemann L, Sha S, Becker RH, Willavize SA, et al. Time-action profile of inhaled insulin in comparison with subcutaneously injected insulin lispro and regular human insulin. Diabetes Care 2005; 28: 1077-82.
    • (2005) Diabetes Care , vol.28 , pp. 1077-1082
    • Rave, K.1    Bott, S.2    Heinemann, L.3    Sha, S.4    Becker, R.H.5    Willavize, S.A.6
  • 51
    • 7444270287 scopus 로고    scopus 로고
    • Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 1 diabetes: Results of a 6-month, randomized, comparative trial
    • Quattrin T, Bélanger A, Bohannon NJ, Schwartz SL. Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 1 diabetes: results of a 6-month, randomized, comparative trial. Diabetes Care 2004; 27: 2622-7.
    • (2004) Diabetes Care , vol.27 , pp. 2622-2627
    • Quattrin, T.1    Bélanger, A.2    Bohannon, N.J.3    Schwartz, S.L.4
  • 52
    • 4644372272 scopus 로고    scopus 로고
    • Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 2 diabetes: Results of a 6-month, randomized, comparative trial
    • Hollander PA, Blonde L, Rowe R, Mehta AE, Milburn JL, Hershon KS, et al. Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 2 diabetes: results of a 6-month, randomized, comparative trial. Diabetes Care 2004; 27: 2356-62.
    • (2004) Diabetes Care , vol.27 , pp. 2356-2362
    • Hollander, P.A.1    Blonde, L.2    Rowe, R.3    Mehta, A.E.4    Milburn, J.L.5    Hershon, K.S.6
  • 53
    • 33846651828 scopus 로고    scopus 로고
    • Inhaled insulin for diabetes mellitus
    • McMahon GT, Arky RA. Inhaled insulin for diabetes mellitus. N Engl J Med 2007; 356: 497-502.
    • (2007) N Engl J Med , vol.356 , pp. 497-502
    • McMahon, G.T.1    Arky, R.A.2
  • 54
    • 6044257275 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and pharmacodynamics of inhaled insulin
    • Patton JS, Bukar JG, Eldon MA. Clinical pharmacokinetics and pharmacodynamics of inhaled insulin. Clin Pharmacokinet 2004; 43: 781-801.
    • (2004) Clin Pharmacokinet , vol.43 , pp. 781-801
    • Patton, J.S.1    Bukar, J.G.2    Eldon, M.A.3
  • 55
    • 34249303939 scopus 로고    scopus 로고
    • accessed March 13, 2006
    • http://www.fda.gov/bbs/topics/news/2OO6/NEW01304.html (accessed March 13, 2006).
  • 56
    • 1042303481 scopus 로고    scopus 로고
    • Intensive therapy with inhaled insulin via the AERx insulin diabetes management system: A 12-week proof-of-concept trial in patients with type 2 diabetes
    • Hermansen K, Ronnemaa T, Petersen AH, Bellaire S, Adamson U. Intensive therapy with inhaled insulin via the AERx insulin diabetes management system: a 12-week proof-of-concept trial in patients with type 2 diabetes. Diabetes Care 2004; 27: 162-7.
    • (2004) Diabetes Care , vol.27 , pp. 162-167
    • Hermansen, K.1    Ronnemaa, T.2    Petersen, A.H.3    Bellaire, S.4    Adamson, U.5
  • 57
    • 22144472560 scopus 로고    scopus 로고
    • Inhaled insulin for diabetes mellitus
    • Mandal TK. Inhaled insulin for diabetes mellitus. Am J Health-System Pharmacy 2005; 62: 1359-64.
    • (2005) Am J Health-System Pharmacy , vol.62 , pp. 1359-1364
    • Mandal, T.K.1
  • 58
    • 25644437167 scopus 로고    scopus 로고
    • Dose response of inhaled dry-powder insulin and dose equivalence to subcutaneous insulin lispro
    • Rave KM, Nosek L, de la Pena A, Seger M, Ernest CS 2nd, Heinemann L, et al. Dose response of inhaled dry-powder insulin and dose equivalence to subcutaneous insulin lispro. Diabetes Care 2005; 28: 2400-5.
    • (2005) Diabetes Care , vol.28 , pp. 2400-2405
    • Rave, K.M.1    Nosek, L.2    de la Pena, A.3    Seger, M.4    Ernest 2nd, C.S.5    Heinemann, L.6
  • 59
    • 28244484920 scopus 로고    scopus 로고
    • Pulmonary insulin delivery by means of the Technosphere drug carrier mechanism
    • Pfutzner A, Forst T. Pulmonary insulin delivery by means of the Technosphere drug carrier mechanism. Expert Opin Drug Deliv 2005; 2: 1097-106.
    • (2005) Expert Opin Drug Deliv , vol.2 , pp. 1097-1106
    • Pfutzner, A.1    Forst, T.2
  • 60
    • 34249312401 scopus 로고    scopus 로고
    • accessed March 13, 2006
    • http://www.generex.com (accessed March 13, 2006).
  • 61
    • 1242276363 scopus 로고    scopus 로고
    • Beneficial effects of addition of oral spray insulin (Oralin) on insulin secretion and metabolic control in subjects with type 2 diabetes mellitus suboptimally controlled on oral hypoglycemic agents
    • Guevara-Aguirre J, Guevara M, Saavedra J, Mihic M, Modi P. Beneficial effects of addition of oral spray insulin (Oralin) on insulin secretion and metabolic control in subjects with type 2 diabetes mellitus suboptimally controlled on oral hypoglycemic agents. Diabetes Technol Ther 2004; 6: 1-8.
    • (2004) Diabetes Technol Ther , vol.6 , pp. 1-8
    • Guevara-Aguirre, J.1    Guevara, M.2    Saavedra, J.3    Mihic, M.4    Modi, P.5
  • 62
    • 34249275071 scopus 로고    scopus 로고
    • accessed March 13, 2006
    • http://www.nobex.com (accessed March 13, 2006).
  • 63
    • 0038390434 scopus 로고    scopus 로고
    • Control of postprandial plasma glucose by an oral insulin product (HIM2) in patients with type 2 diabetes
    • Kipnes M, Dandona P, Tripathy D, Still JG, Kosutic G. Control of postprandial plasma glucose by an oral insulin product (HIM2) in patients with type 2 diabetes. Diabetes Care 2003; 26: 421-6.
    • (2003) Diabetes Care , vol.26 , pp. 421-426
    • Kipnes, M.1    Dandona, P.2    Tripathy, D.3    Still, J.G.4    Kosutic, G.5
  • 65
    • 34249338182 scopus 로고    scopus 로고
    • accessed March 13, 2006
    • http://www.alteatherapeutics.com/ (accessed March 13, 2006).
  • 66
    • 34249303232 scopus 로고    scopus 로고
    • accessed March 13, 2006
    • http://www.dermisonics.com/ (accessed March 13, 2006).
  • 67
    • 34249297752 scopus 로고    scopus 로고
    • accessed March 13, 2006
    • http://www.starbridgesystems.co.uk/ (accessed March 13, 2006).
  • 68
    • 13544271146 scopus 로고    scopus 로고
    • Current status and future of implantable insulin pumps for the treatment of diabetes
    • Catargi B. Current status and future of implantable insulin pumps for the treatment of diabetes. Expert Rev Med Devices 2004; 1: 181-5.
    • (2004) Expert Rev Med Devices , vol.1 , pp. 181-185
    • Catargi, B.1
  • 70
    • 0032754795 scopus 로고    scopus 로고
    • Continuous glucose monitoring used to adjust diabetes therapy improves glycosylated hemoglobin: A pilot study
    • Bode BW, Gross TM, Thornton KR, Mastrototaro JJ. Continuous glucose monitoring used to adjust diabetes therapy improves glycosylated hemoglobin: a pilot study. Diabetes Res Clin Pract 1999; 46: 183-90.
    • (1999) Diabetes Res Clin Pract , vol.46 , pp. 183-190
    • Bode, B.W.1    Gross, T.M.2    Thornton, K.R.3    Mastrototaro, J.J.4
  • 71
    • 0034493835 scopus 로고    scopus 로고
    • The economic burden of diabetes and the benefits of improved glycemic control: The potential role of a continuous glucose monitoring system
    • Skyler JS. The economic burden of diabetes and the benefits of improved glycemic control: the potential role of a continuous glucose monitoring system. Diabetes Technol Ther 2000; 2 (Suppl 1): S7-12.
    • (2000) Diabetes Technol Ther , vol.2 , Issue.SUPPL. 1
    • Skyler, J.S.1
  • 72
    • 27644556801 scopus 로고    scopus 로고
    • A review of continuous glucose monitoring technology
    • Klonoff DC. A review of continuous glucose monitoring technology. Diabetes Technol Ther 2005; 7: 770-5.
    • (2005) Diabetes Technol Ther , vol.7 , pp. 770-775
    • Klonoff, D.C.1
  • 75
    • 18144373420 scopus 로고    scopus 로고
    • A randomized multicenter trial comparing the Gluco Watch Biographer with standard glucose monitoring in children with type 1 diabetes
    • Chase HP, Beck R, Tamborlane W, Buckingham B, Mauras N, Tsalikian E, et al. A randomized multicenter trial comparing the Gluco Watch Biographer with standard glucose monitoring in children with type 1 diabetes. Diabetes Care 2005; 28: 1101-6.
    • (2005) Diabetes Care , vol.28 , pp. 1101-1106
    • Chase, H.P.1    Beck, R.2    Tamborlane, W.3    Buckingham, B.4    Mauras, N.5    Tsalikian, E.6
  • 76
    • 1442324399 scopus 로고    scopus 로고
    • Improved glucose excursions using an implantable real-time continuous glucose sensor in adults with type 1 diabetes
    • Garg SK, Schwartz S, Edelman SV. Improved glucose excursions using an implantable real-time continuous glucose sensor in adults with type 1 diabetes. Diabetes Care 2004; 27: 734-8.
    • (2004) Diabetes Care , vol.27 , pp. 734-738
    • Garg, S.K.1    Schwartz, S.2    Edelman, S.V.3
  • 77
    • 4344615386 scopus 로고    scopus 로고
    • Impact of posture and fixation technique on impedance spectroscopy used for continuous and noninvasive glucose monitoring
    • Pfutzner A, Caduff A, Larbig M, Schrepfer T, Forst T. Impact of posture and fixation technique on impedance spectroscopy used for continuous and noninvasive glucose monitoring. Diabetes Technol Ther 2004; 6: 435-41.
    • (2004) Diabetes Technol Ther , vol.6 , pp. 435-441
    • Pfutzner, A.1    Caduff, A.2    Larbig, M.3    Schrepfer, T.4    Forst, T.5
  • 78
    • 33644875792 scopus 로고    scopus 로고
    • Improvement in glycemic excursions with a transcutaneous, Real-time continuous glucose sensor: A randomized controlled trial
    • Garg S, Zisser H, Schwartz S, Bailey T, Kaplan R, Ellis S, et al. Improvement in glycemic excursions with a transcutaneous, Real-time continuous glucose sensor: A randomized controlled trial. Diabetes Care 2006; 29: 4-50.
    • (2006) Diabetes Care , vol.29 , pp. 4-50
    • Garg, S.1    Zisser, H.2    Schwartz, S.3    Bailey, T.4    Kaplan, R.5    Ellis, S.6
  • 79
    • 0030935652 scopus 로고    scopus 로고
    • Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study
    • Pan XR, Li GW, Hu YH, Wang JX, Yang WY, An ZX, et al. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care 1997; 20: 537-44.
    • (1997) Diabetes Care , vol.20 , pp. 537-544
    • Pan, X.R.1    Li, G.W.2    Hu, Y.H.3    Wang, J.X.4    Yang, W.Y.5    An, Z.X.6
  • 82
    • 31844452061 scopus 로고    scopus 로고
    • The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1)
    • Ramachandran A, Snehalatha C, Mary S, Mukesh B, Bhaskar AD, Vijay V. The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1). Diabetologia 2006; 49: 289-97.
    • (2006) Diabetologia , vol.49 , pp. 289-297
    • Ramachandran, A.1    Snehalatha, C.2    Mary, S.3    Mukesh, B.4    Bhaskar, A.D.5    Vijay, V.6
  • 83
    • 25644436429 scopus 로고    scopus 로고
    • Lipid, lipoproteins, C-reactive protein, and hemostatic factors at baseline in the diabetes prevention program
    • The Diabetes Prevention Program Research Group
    • The Diabetes Prevention Program Research Group. Lipid, lipoproteins, C-reactive protein, and hemostatic factors at baseline in the diabetes prevention program. Diabetes Care 2005; 28: 2472-9.
    • (2005) Diabetes Care , vol.28 , pp. 2472-2479
  • 84
    • 0037097039 scopus 로고    scopus 로고
    • Acarbose for prevention of type 2 diabetes mellitus: The STOP-NIDDM randomized trial
    • Chiasson JL, Josse RG, Gomis R, Hanefeld M, Karasik A, Laakso M. Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomized trial. Lancet 2002; 359: 2072-7.
    • (2002) Lancet , vol.359 , pp. 2072-2077
    • Chiasson, J.L.1    Josse, R.G.2    Gomis, R.3    Hanefeld, M.4    Karasik, A.5    Laakso, M.6
  • 85
    • 15944395414 scopus 로고    scopus 로고
    • Prevention of type 2 diabetes with troglitazone in the Diabetes Prevention Program. The Diabetes Prevention Program Research Group
    • Prevention of type 2 diabetes with troglitazone in the Diabetes Prevention Program. The Diabetes Prevention Program Research Group. Diabetes 2005; 54: 1150-6.
    • (2005) Diabetes , vol.54 , pp. 1150-1156
  • 86
    • 1042303480 scopus 로고    scopus 로고
    • Torgerson JS, Hauptman J, Boldrin MN, Sjostrom L. Xenical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care 2004; 27: 155-61.
    • Torgerson JS, Hauptman J, Boldrin MN, Sjostrom L. Xenical in the prevention of diabetes in obese subjects (XENDOS) study: a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients. Diabetes Care 2004; 27: 155-61.
  • 88
    • 1042291850 scopus 로고    scopus 로고
    • Antihypertensive therapy and incidence of type 2 diabetes: A systematic review
    • Padwal R, Laupacis A. Antihypertensive therapy and incidence of type 2 diabetes: a systematic review. Diabetes Care 2004; 27: 247-55.
    • (2004) Diabetes Care , vol.27 , pp. 247-255
    • Padwal, R.1    Laupacis, A.2
  • 89
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • for the West of Scotland Coronary Prevention Study Group
    • Shepherd J, Cobbe SM, Ford I, Isles CG, Lorimer AR, MacFarlane PW, et al, for the West of Scotland Coronary Prevention Study Group. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med 1995; 333: 1301-8.
    • (1995) N Engl J Med , vol.333 , pp. 1301-1308
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3    Isles, C.G.4    Lorimer, A.R.5    MacFarlane, P.W.6
  • 90
    • 1542345696 scopus 로고    scopus 로고
    • Heart Protection Study Collaborative Group. Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions
    • Collins R, Armitage J, Parish S, Sleight P, Peto R; Heart Protection Study Collaborative Group. Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions. Lancet 2004; 363 757-67.
    • (2004) Lancet , vol.363 , pp. 757-767
    • Collins, R.1    Armitage, J.2    Parish, S.3    Sleight, P.4    Peto, R.5
  • 91
    • 10744228379 scopus 로고    scopus 로고
    • Secondary prevention of cardiovascular events with long-term pravastatin in patients with diabetes or impaired fasting glucose
    • Keech A, Colquhoun D, Best J, Kirby A, Simes RJ, Hunt D, et al. Secondary prevention of cardiovascular events with long-term pravastatin in patients with diabetes or impaired fasting glucose. Diabetes Care 2003; 26: 2713-21.
    • (2003) Diabetes Care , vol.26 , pp. 2713-2721
    • Keech, A.1    Colquhoun, D.2    Best, J.3    Kirby, A.4    Simes, R.J.5    Hunt, D.6
  • 92
    • 0037420492 scopus 로고    scopus 로고
    • Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): A multicentre randomised controlled trial
    • Sever PS, Dahlof B, Poulter NR, Wedel H, Beevers G, Caulfield M, et al. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 2003; 361: 1149-58.
    • (2003) Lancet , vol.361 , pp. 1149-1158
    • Sever, P.S.1    Dahlof, B.2    Poulter, N.R.3    Wedel, H.4    Beevers, G.5    Caulfield, M.6
  • 93
    • 2442660528 scopus 로고    scopus 로고
    • Peroxisome proliferators-activated receptor ligand Bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease
    • Tenenbaum A, Motro M, Fisman EZ, Schwammenthal E, Adler Y, Goldenberg I, et al. Peroxisome proliferators-activated receptor ligand Bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease. Circulation 2004; 109: 2197-202.
    • (2004) Circulation , vol.109 , pp. 2197-2202
    • Tenenbaum, A.1    Motro, M.2    Fisman, E.Z.3    Schwammenthal, E.4    Adler, Y.5    Goldenberg, I.6
  • 94
    • 0037422848 scopus 로고
    • Glycemic effects of postmenopausal hormone therapy: The heart and estrogen/progestin replacement study
    • Kanaya AM, Herrington D, Vittinghoff E Lin F, Grady D, Bittner V, et al. Glycemic effects of postmenopausal hormone therapy: the heart and estrogen/progestin replacement study. Ann Intern Med 1992; 138: 1-9.
    • (1992) Ann Intern Med , vol.138 , pp. 1-9
    • Kanaya, A.M.1    Herrington, D.2    Vittinghoff, E.3    Lin, F.4    Grady, D.5    Bittner, V.6
  • 96
    • 5644250670 scopus 로고    scopus 로고
    • The DREAM Trial Investigators. Rationale, design and recruitment characteristics of a large, simple international trial of diabetes prevention: The DREAM trial
    • Gerstein HC, Yusuf S, Holman R, Bosch J, Pogue J. The DREAM Trial Investigators. Rationale, design and recruitment characteristics of a large, simple international trial of diabetes prevention: the DREAM trial. Diabetologia 2004; 47: 1519-27.
    • (2004) Diabetologia , vol.47 , pp. 1519-1527
    • Gerstein, H.C.1    Yusuf, S.2    Holman, R.3    Bosch, J.4    Pogue, J.5
  • 97
    • 22044453941 scopus 로고    scopus 로고
    • The diabetes pandemic: Looking for the silver lining
    • Venkat Narayan KM. The diabetes pandemic: Looking for the silver lining. Clin Diabetes 2005; 23: 51-2.
    • (2005) Clin Diabetes , vol.23 , pp. 51-52
    • Venkat Narayan, K.M.1


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