Influence of the preparation method on residual solvents in biodegradable microspheres

International Journal of Pharmaceutics

Volumn 131, Issue 2, 1996, Pages 171-181

  Bitz, Claudia ^a   Doelker, Eric ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Biodegradable microspheres; Headspace chromatography; Multiple headspace extraction; Poly(DL lactic co glycolic acid); Poly(L lactic acid); Preparation method; Residual solvents

Indexed keywords

CHLOROFORM; DICHLOROMETHANE; DRUG RESIDUE; MEDISORB 100L; METHANOL; MICROSPHERE; POLYGLACTIN; POLYLACTIC ACID; RESOMER RG755; SOLVENT; TETRACOSACTIDE; UNCLASSIFIED DRUG;

ARTICLE; CHROMATOGRAPHY; ENCAPSULATION; EVAPORATION; EXTRACTION; HEAD; MORPHOLOGY; PARTICLE SIZE; PRIORITY JOURNAL; TEMPERATURE;

EID: 0029938986     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(95)04320-9     Document Type: Article

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