Super long-term glycemic control in diabetic rats by glucose-sensitive LbL films constructed of supramolecular insulin assembly

Biomaterials

Volumn 33, Issue 33, 2012, Pages 8733-8742

  Luo, Jun ^a   Cao, Shuqin ^a   Chen, Xingyu ^a   Liu, Shuning ^a   Tan, Hong ^a   Wu, Wei ^a   Li, Jianshu ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Diabetes; Drug delivery; Layer by layer assembly; Long term controlled release; Supramolecular insulin assembly

Indexed keywords

2-(DIMETHYLAMINO)ETHYL METHACRYLATE; AMYLOID FIBRIL; BIOMEDICAL DEVICES; CONTROLLED RELEASE; DIABETIC RATS; DRUG DELIVERY SYSTEM; GLUCOSE SENSITIVES; GLYCEMIC CONTROL; IN-VITRO; INSULIN RELEASE; LAYER-BY-LAYER ASSEMBLIES; LAYER-BY-LAYER FILMS; REGULATION CAPABILITY; RELEASE TIME; RICH STRUCTURE; SINGLE-DOSE; SUPRAMOLECULAR ASSEMBLIES; THIOFLAVIN T;

BIOLOGICAL MATERIALS; DRUG DELIVERY; GLUCOSE; GLUCOSE SENSORS; MEDICAL PROBLEMS; RATS; STARS; SUPRAMOLECULAR CHEMISTRY;

INSULIN;

AMYLOID; CATALASE; GLUCOSE; GLUCOSE OXIDASE; HYDROGEN PEROXIDE; INSULIN; NANOFILM; PIG INSULIN; POLY[2 (DIMETHYLAMINO)ETHYL METHACRYLATE]; SUPRAMOLECULAR ASSEMBLY OF PORCINE INSULIN; THIOFLAVINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA SHEET; CONTROLLED STUDY; DIABETES MELLITUS; DRUG DELIVERY SYSTEM; FLUORESCENCE; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HYPOGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; LAYER BY LAYER FILM; LONG TERM CARE; MALE; MORPHOLOGY; NANOFABRICATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD GLUCOSE; CATALASE; DIABETES MELLITUS, EXPERIMENTAL; DRUG DELIVERY SYSTEMS; GLUCOSE OXIDASE; INSULIN; MALE; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS; SUS;

EID: 84866159974     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.08.041     Document Type: Article

References (48)

1. Cheung A.T., Dayanandan B., Lewis J.T., Korbutt G.S., Rajotte R.V., Bryer-Ash M., et al. Glucose-dependent insulin release from genetically engineered K cells. Science 2000, 290:1959-1962.
2. Guiseppi-Elie A., Brahim S.I., Narinesingh D. A chemically synthesized artificial pancreas: release of insulin from glucose-responsive hydrogels. Adv Mater 2002, 14:743-746.
3. Zhao Y.N., Trewyn B.G., Slowing, Lin V.S.Y. Mesoporous silica nanoparticle-based double drug delivery system for glucose-responsive controlled release of insulin and cyclic AMP. J Am Chem Soc 2009, 131:8398-8400.
4. Phillips N.B., Wan Z., Whittaker L., Hu S., Huang K., Hua Q., et al. Supramolecular protein engineering: design of zinc-stapled insulin hexamers as a long acting depot. J Biol Chem 2010, 285:11755-11759.
5. Bluestone J.A., Herold K., Eisenbarth G. Genetics, pathogenesis and clinical interventions in type 1 diabetes. Nature 2010, 464:1293-1300.
6. 30)]insulin (" ester insulin" ): a minimal proinsulin surrogate that can be chemically converted into human insulin. Angew Chem Int Ed 2010, 49:5489-5493.
7. Wu W.T., Mitra N., Yan E.C.Y., Zhou S.Q. Multifunctional hybrid nanogel for integration of optical glucose sensing and self-regulated insulin release at physiological pH. ACS Nano 2010, 4:4831-4839.
8. Kashyap N., Viswanad B., Sharma G., Bhardwaj V., Ramarao P., Ravi Kumar M.N.V. Design and evaluation of biodegradable, biosensitive in situ gelling system for pulsatile delivery of insulin. Biomaterials 2007, 28:2051-2060.
9. Huynh D.P., Nguyen M.K., Pi B.S., Kim M.S., Chae S.Y., Lee K.C., et al. Functionalized injectable hydrogels for controlled insulin delivery. Biomaterials 2008, 29:2527-2534.
10. Luo R., Li H., Lam K.Y. Modeling the effect of environmental solution pH on the mechanical characteristics of glucose-sensitive hydrogels. Biomaterials 2009, 30:690-700.
11. Traitel T., Cohen Y., Kost J. Characterization of glucose-sensitive insulin release systems in simulated in vivo conditions. Biomaterials 2000, 21:1679-1687.
12. Carino G.P., Mathiowitz E. Oral insulin delivery. Adv Drug Deliv Rev 1999, 35:249-257.
13. Zambanini A., Newson R.B., Maisey M., Feher M.D. Injection related anxiety in insulin-treated diabetes. Diabetes Res Clin Pract 1999, 46:239-246.
14. Ricordi C., Strom T.B. Clinical islet transplantation: advances and immunological challenges. Nat Rev Immunol 2004, 4:259-268.
15. Nowakowska M., Jarosz-chobot P., Polanska J., Machnica L. Bacterial strains colonizing subcutaneous catheters of personal insulin pumps. Pol J Microbiol 2007, 56:239-243.
16. Shalitin S., Phillip M. Hypoglycemia in type 1 diabetes: a still unresolved problem in the era of insulin analogs and pump therapy. Diabetes Care 2008, 31:S121-S124.
17. Wang W., Nema S., Teagarden D. Protein aggregation-pathways and influencing factors. Int J Pharm 2010, 390:89-99.
18. Bieschke J., Russ J., Friedrich R.P., Ehrnhoefer D.E., Wobst H., Neugebauer K., et al. EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity. Proc Natl Acad Sci U S A 2010, 107:7710-7715.
19. Gupta S., Chattopadhyay T., Singh M.P., Surolia A. Supramolecular insulin assembly II for a sustained treatment of type 1 diabetes mellitus. Proc Natl Acad Sci U S A 2010, 107:13246-13251.
20. Bagla P. Keeping insulin hanging around. Sci Now 2010, Available from: URL:. http://news.sciencemag.org/sciencenow/2010/07/keeping-insulin-hanging-around.html.
21. Zoungas S., Patel A., Chalmers J., de Galan B.E., Li Q., Billot L., et al. Severe hypoglycemia and risks of vascular events and death. N Engl J Med 2010, 363:1410-1418.
22. Gruden G., Barutta F., Chaturvedi N., Schalkwijk C., Stehouwer C.D., Witte D.R., et al. Severe hypoglycemia and cardiovascular disease incidence in type 1 diabetes the EURODIAB prospective complications study. Diabetes Care 2012, 35:1598-1604.
23. Dische F.E., Wernstedt C., Westermark G.T., Westermark P., Pepys M.B., Rennie J.A., et al. Insulin as an amyloid-fibril protein at sites of repeated insulin injections in a diabetic patient. Diabetologia 1988, 31:158-161.
24. Swift B., Hawkins P.N., Richards C., Gregory R. Examination of insulin injection sites: an unexpected finding of localized amyloidosis. Diabet Med 2002, 19:881-882.
25. Smith U., Gale E.A.M. Does diabetes therapy influence the risk of cancer?. Diabetologia 2009, 52:1699-1708.
26. Hemkens L.G., Grouven U., Bender R., Gunster C., Gutschmidt S., Selke G.W., et al. Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: a cohort study. Diabetologia 2009, 52:1732-1744.
27. Yoshida K., Sato H., Takahashi S., Anzai J. Preparation of layer-by-layer thin films containing insulin and its pH-sensitive decomposition. Polym J 2008, 40:90-91.
28. Qi W., Yan X., Fei J., Wang A., Cui Y., Li J. Triggered release of insulin from glucose-sensitive enzyme multilayer shells. Biomaterials 2009, 30:2799-2806.
29. Yoshida K., Sato K., Anzai J. Layer-by-layer polyelectrolyte films containing insulin for pH-triggered release. J Mater Chem 2010, 20:1546-1552.
30. Connal L.A., Li Q., Quinn J.F., Tjipto E., Caruso F., Qiao G.G. pH-Responsive poly(acrylic acid) core cross-linked star polymers: morphology transitions in solution and multilayer thin films. Macromolecules 2008, 41:2620-2626.
31. Kim B.S., Gao H., Argun A.A., Matyjaszewski K., Hammond P.T. All-star polymer multilayers as pH-responsive nanofilms. Macromolecules 2009, 42:368-375.
32. Guo Z., Chen X., Xin J., Wu D., Li J., Xu C. Effect of molecular weight and arm number on the growth and pH-dependent morphology of star poly[2-(dimethylamino)ethyl methacrylate]/poly(styrenesulfonate) multilayer films. Macromolecules 2010, 43:9087-9093.
33. Chen X., Wu W., Guo Z., Xin J., Li J. Controlled insulin release from glucose-sensitive self-assembled multilayer films based on 21-arm star polymer. Biomaterials 2011, 32:1759-1766.
34. Chen X., Luo J., Wu W., Tan H., Xu F., Li J. The influence of arrangement sequence on the glucose-responsive controlled release profiles of insulin-incorporated LbL films. Acta Biomater 2012, Available from:. 10.1016/j.actbio.2012.08.014.
35. Chen X., Guo Z., Xin J., Li J., Li J. Modulated insulin release from glucose-sensitive multilayer films. J Control Release 2011, 152:e152-e154.
36. Wu W., Liu J., Cao S., Tan H., Li J., Xu F., et al. Drug release behaviors of a pH sensitive semi-interpenetrating polymer network hydrogel composed of poly(vinyl alcohol) and star poly[2-(dimethylamino)ethyl methacrylate]. Int J Pharm 2011, 416:104-109.
37. Biancalana M., Koide S. Molecular mechanism of thioflavin-T binding to amyloid fibrils. Biochim Biophys Acta Proteins Proteomics 2010, 1804:1405-1412.
38. Surewicz W.K., Mantsch H.H., Chapman D. Determination of protein secondary structure by fourier transform infrared spectroscopy: a critical assessment. Biochemistry 1993, 32:389-394.
39. Bouchard M., Zurdo J., Nettleton E.J., Dobson C.M., Robinson C.V. Formation of insulin amyloid fibrils followed by FTIR simultaneously with CD and electron microscopy. Protein Sci 2000, 9:1960-1967.
40. Ahmad A., Uversky V.N., Hong D., Fink A.L. Early events in the fibrillation of monomeric insulin. J Biol Chem 2005, 280:42669-42675.
41. Ahmad A., Millett I.S., Doniach S., Uversky V.N., Fink A.L. Partially folded intermediates in insulin fibrillation. Biochemistry 2003, 42:11404-11416.
42. Jansen R., Dzwolak W., Winter R. Amyloidogenic self-assembly of insulin aggregates probed by high resolution atomic force microscopy. Biophys J 2005, 88:1344-1353.
43. Christakis O.M., Weiland R.H. On the mechanism of immobilized glucose oxidase deactivation by hydrogen peroxide. Biotechnol Bioeng 1982, 24:2419-2439.
44. Lucisano J.Y., Gough D.A. Transient response of the two-dimensional glucose sensor. Anal Chem 1988, 60:1272-1281.
45. Klumb L.A., Horbett T.A. Design of insulin delivery devices based on glucose sensitive membranes. J Control Release 1992, 18:59-80.
46. Jung D.Y., Magda J.J., Han I.S. Catalase effects on glucose-sensitive hydrogels. Macromolecules 2000, 33:3332-3336.
47. Pantarotto D., Browne W.R., Feringa B.L. Autonomous propulsion of carbon nanotubes powered by a multienzyme ensemble. Chem Commun 2008, 1533-1535.
48. Kujawa P., Moraille P., Sanchez J., Badia A., Winnik F.M. Effect of molecular weight on the exponential growth and morphology of hyaluronan/chitosan multilayers: a surface plasmon resonance spectroscopy and atomic force microscopy investigation. J Am Chem Soc 2005, 127:9224-9234.