Association between Polymorphisms of the IL-23R Gene and Allergic Rhinitis in a Chinese Han Population

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Hu, Di ^a   Hu, Guohua ^a   Zhu, Jing ^a   Shen, Yang ^a   Kang, Houyong ^a   Hong, Suling ^a  

^a THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; INTERLEUKIN 23 RECEPTOR;

ADOLESCENT; ADULT; AGED; ALLELE; ALLERGIC RHINITIS; ARTICLE; CASE CONTROL STUDY; CHILD; CHINESE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HOMOZYGOSITY; HUMAN; IL 23R GENE; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PROTECTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTORS, INTERLEUKIN; RHINITIS, ALLERGIC, PERENNIAL;

EID: 84877798414     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063858     Document Type: Article

References (29)

1. Holgate ST, (1999) The epidemic of allergy and asthma. Nature 402: B2-4.
2. Bousquet J, Burney PG, Zuberbier T, Cauwenberge PV, Akdis CA, et al. (2009) GA2LEN (Global Allergy and Asthma European Network) addresses the allergy and asthma 'epidemic'. Allergy 64: 969-977.
3. Shen J, Ke X, Hong S, Zeng Q, Liang C, et al. (2011) Epidemiological features of allergic rhinitis in four major cities in Western China. Journal of Huazhong University of Science and Technology Medical sciences = Hua zhong ke ji da xue xue bao Yi xue Ying De wen ban = Huazhong keji daxue xuebao Yixue Yingdewen ban 31: 433-440.
4. Genuneit J, Cantelmo JL, Weinmayr G, Wong GW, Cooper PJ, et al. (2009) A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2. Clin Exp Allergy 39: 1875-1888.
5. Gaddam SL, Priya VHS, Babu BMVS, Joshi L, Venkatasubramanian S, et al. (2012) Association of interleukin-10 gene promoter polymorphism in allergic patients. Genetic testing and molecular biomarkers 16: 632-635.
6. G HI, Eltabbakh MT, Gomaa AH, Mohamed EA (2012) Interleukin-18 gene polymorphisms in Egyptian patients with allergic diseases. Am J Rhinol Allergy.
7. Zhang Y, Lin X, Desrosiers M, Zhang W, Meng N, et al. (2011) Association pattern of interleukin-1 receptor-associated kinase-4 gene polymorphisms with allergic rhinitis in a Han Chinese population. PloS one 6: e21769.
8. Andiappan AK, Wang DY, Anantharaman R, Parate PN, Suri BK, et al. (2011) Genome-wide association study for atopy and allergic rhinitis in a Singapore Chinese population. PloS one 6: e19719.
9. Ciprandi G, De Amici M, Murdaca G, Fenoglio D, Ricciardolo F, et al. (2009) Serum interleukin-17 levels are related to clinical severity in allergic rhinitis. Allergy 64: 1375-1378.
10. Wang M, Zhang Y, Han D, Zhang L, (2012) Association between polymorphisms in cytokine genes IL-17A and IL-17F and development of allergic rhinitis and comorbid asthma in Chinese subjects. Human immunology 73: 647-653.
11. McKenzie BS, Kastelein RA, Cua DJ, (2006) Understanding the IL-23-IL-17 immune pathway. Trends Immunol 27: 17-23.
12. McGovern D, Powrie F, (2007) The IL23 axis plays a key role in the pathogenesis of IBD. Gut 56: 1333-1336.
13. Zhu K-J, Zhu C-Y, Shi G, Fan Y-M, (2012) Association of IL23R polymorphisms with psoriasis and psoriatic arthritis: a meta-analysis. Inflammation research: official journal of the European Histamine Research Society [et al] 61: 1149-1154.
14. Jiang Z, Yang P, Hou S, Du L, Xie L, et al. (2010) IL-23R gene confers susceptibility to Behcet's disease in a Chinese Han population. Ann Rheum Dis 69: 1325-1328.
15. Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, et al. (2008) Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 63Suppl 86: 8-160.
16. Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, et al. (2006) A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (New York, N Y) 314: 1461-1463.
17. Juyal G, Prasad P, Senapati S, Midha V, Sood A, et al. (2011) An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians. PloS one 6: e16565.
18. Glas J, Seiderer J, Nagy M, Fries C, Beigel F, et al. (2010) Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset. PloS one 5: e10373.
19. Glas J, Seiderer J, Wetzke M, Konrad A, Torok H-P, et al. (2007) rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. PloS one 2: e819.
20. Karaderi T, Harvey D, Farrar C, Appleton LH, Stone MA, et al. (2009) Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case-control study and meta-analysis of published series. Rheumatology (Oxford, England) 48: 386-389.
21. Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, et al. (2007) Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 39: 596-604.
22. Zhang X-Y, Zhang H-J, Zhang Y, Fu Y-J, He J, et al. (2006) Identification and expression analysis of alternatively spliced isoforms of human interleukin-23 receptor gene in normal lymphoid cells and selected tumor cells. Immunogenetics 57: 934-943.
23. Safrany E, Melegh B, (2009) Functional variants of the interleukin-23 receptor gene in non-gastrointestinal autoimmune diseases. Curr Med Chem 16: 3766-3774.
24. Parham C, Chirica M, Timans J, Vaisberg E, Travis M, et al. (2002) A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R. Journal of immunology (Baltimore, Md: 1950) 168: 5699-5708.
25. Hoeve MA, Savage NDL, de Boer T, Langenberg DML, de Waal Malefyt R, et al. (2006) Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells. European journal of immunology 36: 661-670.
26. Chen Z, Tato CM, Muul L, Laurence A, O'Shea JJ, (2007) Distinct regulation of interleukin-17 in human T helper lymphocytes. Arthritis and rheumatism 56: 2936-2946.
27. Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B, (2006) TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24: 179-189.
28. Di Cesare A, Di Meglio P, Nestle FO, (2009) The IL-23/Th17 axis in the immunopathogenesis of psoriasis. The Journal of investigative dermatology 129: 1339-1350.
29. Michel S, Liang L, Depner M, Klopp N, Ruether A, et al. (2010) Unifying candidate gene and GWAS Approaches in Asthma. PloS one 5: e13894.