Association pattern of interleukin-1 receptor-associated kinase-4 gene polymorphisms with allergic rhinitis in a Han Chinese population

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Zhang, Yuan ^a,b   Lin, Xiaoping ^c   Desrosiers, Martin ^d,e   Zhang, Wei ^a   Meng, Na ^a   Zhao, Liping ^a   Han, Demin ^a,b   Zhang, Luo ^a,b  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

^d CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^e MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE;

ADOLESCENT; ADULT; AGED; ALLERGIC RHINITIS; ARTICLE; CHILD; CHINESE; CONTROLLED STUDY; FEMALE; GENE; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HOUSE DUST ALLERGY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN BLOOD LEVEL; IRAK 4 GENE; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; ALLELE; ASIAN; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; RHINITIS;

PYROGLYPHIDAE;

ADOLESCENT; ADULT; AGED; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CHILD; CHILD, PRESCHOOL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RHINITIS; YOUNG ADULT;

EID: 79959728777     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021769     Document Type: Article

References (49)

1. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee (1998) Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. Lancet 351: 1225-1232.
2. Zhang L, Han D, Huang D, Wu Yangfeng, Dong Zhen, et al. (2009) Prevalence of self-reported allergic rhinitis in eleven major cities in china. Int Arch Allergy Immunol 149: 47-57.
3. Okada H, Kuhn C, Feillet H, Bach JF, (2010) The 'hygiene hypothesis' for autoimmune and allergic diseases: an update. Clin Exp Immunol 160: 1-9.
4. Suzuki N, Saito T, (2006) IRAK-4-a shared NF-kappaB activator in innate and acquired immunity. Trends Immunol 27: 566-572.
5. Suzuki N, Suzuki S, Millar DG, Unno M, Hara H, et al. (2006) A critical role for the innate immune signaling molecule IRAK-4 in T cell activation. Science 311: 1927-1932.
6. Netea MG, Sutmuller R, Hermann C, Van der Graaf CA, et al. (2004) Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells. J Immunol 172: 3712-3718.
7. Peng G, Guo Z, Kiniwa Y, Voo KS, Peng W, et al. (2005) Toll-like receptor 8-mediated reversal of CD4+regulatory T cell function. Science 309: 1380-1384.
8. Hornung V, Rothenfusser S, Britsch S, Krug A, Jahrsdörfer B, et al. (2002) Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 168: 4531-4537.
9. Zarember KA, Godowski PJ, (2002) Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J Immunol 168: 554-561.
10. Bacchetta R, Gambineri E, Roncarolo MG, (2007) Role of regulatory T cells and FOXP3 in human diseases. J Allergy Clin Immunol 120: 227-235.
11. Mullol J, Valero A, Alobid I, Bartra J, Navarro AM, et al. (2008) Allergic Rhinitis and its Impact on Asthma update (ARIA 2008). The perspective from Spain. J Investig Allergol Clin Immunol 18: 327-334.
12. Dreborg S, Frew A, (1993) Position Paper Allergen standardization and skin tests. Allergy 47 (Suppl.14): 48-82.
13. Altshuler D, Brooks LD, Chakravarti A, Collins FS, Daly MJ, et al. (2005) International HapMap Consortium. A haplotype map of the human genome. Nature 437: 1299-1320.
14. Barrett JC, Fry B, Maller J, Daly MJ, (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21: 263-265.
15. Tewfik MA, Bossé Y, Lemire M, Hudson TJ, Vallée-Smejda S, et al. (2009) Polymorphisms in interleukin-1 receptor-associated kinase 4 are associated with total serum IgE. Allergy 64: 746-753.
16. Moore JH, Gilbert JC, Tsai CT, Chiang FT, Holden T, et al. (2006) A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility. J Theor Biol 241: 252-61.
17. Moore JH, White BC, (2007) Tuning ReliefF for genome-wide genetic analysis. Lect Notes Comput Sci 4447: 166-75.
18. Ritchie MD, Hahn LW, Moore JH, (2003) Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity. Genet Epidemiol 24: 150-7.
19. Hahn LW, Ritchie MD, Moore JH, (2003) Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions. Bioinformatics 19: 376-82.
20. Erdfelder E, Faul F, Buchner A, (1996) GPOWER: A general power analysis program. Behaviour Research Methods, Instruments & Computers 28: 1-11.
21. Kay AB, (2001) Allergy and allergic diseases. N Engl J Med 344: 30-37.
22. Bauer S, Hangel D, Yu P, (2007) Immunobiology of toll-like receptors in allergic disease. Immunobiology 212: 521-533.
23. Strachan DP, (1989) Hay fever, hygiene, and household size. BMJ 299: 1259-1260.
24. Von Mutius E, (2001) Infection: friend or foe in the development of atopy and asthma? The epidemiological evidence. Eur Respir J 18: 872-881.
25. Tabeta K, Georgel P, Janssen E, Du X, Hoebe K, et al. (2004) Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci 101: 3516-3521.
26. Takeda K, Akira S, (2005) Toll-like receptors in innate immunity. Int Immunol 17: 1-14.
27. Ye H, Arron JR, Lamothe B, Cirilli M, Kobayashi T, et al. (2002) Distinct molecular mechanism for initiating TRAF6 signalling. Nature 418: 443-447.
28. Cottalorda A, Verschelde C, Marçais A, Tomkowiak M, Musette P, et al. (2006) TLR2 engagement on CD8 T cells lowers the threshold for optimal antigen-induced T cell activation. Eur J Immunol 36: 810-816.
29. Caron G, Duluc D, Frémaux I, Jeannin P, David C, et al. (2005) Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-g production by memory CD4+T cells. J Immunol 175: 1551-1557.
30. Netea MG, Sutmuller R, Hermann C, Van der Graaf CA, Van der Meer JW, et al. (2004) Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells. J Immunol 172: 3712-3718.
31. Medvedev AE, Lentschat A, Kuhns DB, Blanco JC, Salkowski C, et al. (2003) Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopoly-saccharide and interleukin-1 in a patient with recurrent bacterial infections. J Exp Med 198: 521-531.
32. Picard C, Puel A, Bonnet M, Ku CL, Bustamante J, et al. (2003) Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 299: 2076-2079.
33. Ku CL, Picard C, Erdos M, Jeurissen A, Bustamante J, et al. (2007) IRAK-4 and NEMO mutations in otherwise healthy children with recurrent invasive pneumococcal disease. J Med Genet 44: 16-23.
34. Huebner M, Kim DY, Ewart S, Karmaus W, Sadeghnejad A, et al. (2008) Patterns of GATA3 and IL13 gene polymorphisms associated with childhood rhinitis and atopy in a birth cohort. J Allergy Clin Immunol 121: 408-414.
35. Vercelli D, (2008) Discovering susceptibility genes for asthma and allergy. Nat Rev Immunol 8: 169-182.
36. Kabesch M, Schedel M, Carr D, Woitsch B, Fritzsch C, et al. (2006) IL-4/IL-13 pathway genetics strongly influence serum IgE levels and childhood asthma. J Allergy Clin Immunol 117: 269-274.
37. Hammad H, Chieppa M, Perros F, Willart MA, Germain RN, et al. (2009) House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat Med 15: 410-416.
38. Braun-Fahrländer C, Riedler J, Herz U, Eder W, Waser M, et al. (2002) Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med 347: 869-877.
39. Eisenbarth SC, Piggott DA, Huleatt JW, Visintin I, Herrick CA, et al. (2002) Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med 196: 1645-1651.
40. Trompette A, Divanovic S, Visintin A, Blanchard C, Hegde RS, et al. (2009) Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 457: 585-588.
41. Moore JH, (2005) A global view of epistasis. Nat Genet 37: 13-14.
42. Phillips PC, (2008) Epistasis - the essential role of gene interactions in the structure and evolution of genetic systems. Nat Rev Genet 9: 855-867.
43. Carlborg O, Haley CS, (2004) Epistasis: too often neglected in complex trait studies? Nat Rev Genet 5: 618-625.
44. Moore JH, (2003) The ubiquitous nature of epistasis in determining susceptibility to common human diseases. Hum Hered 56: 73-82.
45. Moffatt MF, Kabesch M, Liang L, Dixon AL, Strachan D, et al. (2007) Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 448: 470-473.
46. Himes BE, Hunninghake GM, Baurley JW, Rafaels NM, Sleiman P, et al. (2009) Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am J Hum Genet 84: 581-593.
47. Choudhry S, Taub M, Mei R, Rodriguez-Santana J, Rodriguez-Cintron W, et al. (2008) Genome-wide screen for asthma in Puerto Ricans: evidence for association with 5q23 region. Hum Genet 123: 455-468.
48. Weidinger SGC, Rodriguez E, Baurecht H, Mempel M, Klopp N, et al. (2008) Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus. PLoS Genet 4: e1000166.
49. Michel S, Liang L, Depner M, Klopp N, Ruether A, et al. (2010) Unifying candidate gene and GWAS Approaches in Asthma. PLoS One 5: e13894.