GPCR responses in vascular smooth muscle can occur predominantly through dual transactivation of kinase receptors and not classical Gαq protein signalling pathways

Life Sciences

Volumn 92, Issue 20-21, 2013, Pages 951-956

  Little, Peter J ^a  

^a RMIT UNIVERSITY   (Australia)

Author keywords

Endothelin 1; Inositol 1,4,5 trisphosphate; Intracellular calcium; PAR 1; Protein serine threonine kinases; Protein tyrosine kinases; Thrombin

Indexed keywords

ANGIOTENSIN II; CALCIUM ION; ENDOTHELIN 1; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE; LIPOPROTEIN; PROTEOGLYCAN; THROMBIN; TYROSINE KINASE RECEPTOR;

ATHEROSCLEROSIS; CALCIUM CELL LEVEL; ENZYME ACTIVATION; HUMAN; NONHUMAN; PROTEIN BINDING; PROTEOGLYCAN SYNTHESIS; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; STIMULATION; TRANSACTIVATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; CALCIUM; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; MUSCLE, SMOOTH, VASCULAR; PROTEOGLYCANS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 84877772522     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.03.017     Document Type: Review

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