Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3β phosphorylation

Journal of Experimental Medicine

Volumn 207, Issue 4, 2010, Pages 867-880

  Tang, Zhongshu ^a   Arjunan, Pachiappan ^a   Lee, Chunsik ^a   Li, Yang ^a   Kumar, Anil ^a   Hou, Xu ^a   Wang, Bin ^b   Wardega, Piotr ^c   Zhang, Fan ^a   Dong, Lijin ^a   Zhang, Yongqing ^d   Zhang, Shi Zhuang ^b   Ding, Hao ^e   Fariss, Robert N ^a   Becker, Kevin G ^d   Lennartsson, Johan ^c   Nagai, Nobuo ^f   Cao, Yihai ^g   Li, Xuri ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b WEIFANG MEDICAL UNIVERSITY   (China)

^c UPPSALA UNIVERSITY   (Sweden)

^d NATIONAL INSTITUTE ON AGING   (United States)

^e UNIVERSITY OF MANITOBA   (Canada)

^f KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^g KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; NEUROTOXIN; NEUTRALIZING ANTIBODY; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PLATELET DERIVED GROWTH FACTOR CC; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL PERMEABILITY; BRAIN NERVE CELL; CELL SURVIVAL; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; IN VIVO STUDY; MOUSE; NERVE CELL LESION; NERVE CELL NECROSIS; NERVE FIBER TRANSECTION; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA NERVE CELL;

ANIMALS; ANTIBODIES; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BRAIN; BRAIN ISCHEMIA; CAPILLARY PERMEABILITY; CELL SURVIVAL; CEREBRAL CORTEX; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GLYCOGEN SYNTHASE KINASE 3; HYDROGEN PEROXIDE; LYMPHOKINES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; N-METHYLASPARTATE; NEOVASCULARIZATION, PATHOLOGIC; NERVE GROWTH FACTORS; NEURONS; OPTIC NERVE INJURIES; PARKINSON DISEASE, SECONDARY; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; RATS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RETINA; RETINAL GANGLION CELLS; RETINAL VESSELS; STROKE VOLUME; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

EID: 77951074818     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20091704     Document Type: Article

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