메뉴 건너뛰기




Volumn 8, Issue 5, 2013, Pages

Selective Roles of Normal and Mutant Huntingtin in Neural Induction and Early Neurogenesis

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; HUNTINGTIN; NOTCH RECEPTOR; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR HES 5;

EID: 84877724489     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064368     Document Type: Article
Times cited : (39)

References (66)
  • 1
    • 45149107487 scopus 로고    scopus 로고
    • Mechanisms of neurodegeneration in Huntington's disease
    • Gil JM, Rego AC, (2008) Mechanisms of neurodegeneration in Huntington's disease. The European journal of neuroscience 27: 2803-2820.
    • (2008) The European Journal of Neuroscience , vol.27 , pp. 2803-2820
    • Gil, J.M.1    Rego, A.C.2
  • 2
    • 0041656292 scopus 로고    scopus 로고
    • The hunt for huntingtin function: interaction partners tell many different stories
    • Harjes P, Wanker EE, (2003) The hunt for huntingtin function: interaction partners tell many different stories. Trends in biochemical sciences 28: 425-433.
    • (2003) Trends in Biochemical Sciences , vol.28 , pp. 425-433
    • Harjes, P.1    Wanker, E.E.2
  • 4
    • 1242338856 scopus 로고    scopus 로고
    • Huntingtin-protein interactions and the pathogenesis of Huntington's disease
    • Li SH, Li XJ, (2004) Huntingtin-protein interactions and the pathogenesis of Huntington's disease. Trends in genetics: TIG 20: 146-154.
    • (2004) Trends in Genetics: TIG , vol.20 , pp. 146-154
    • Li, S.H.1    Li, X.J.2
  • 6
    • 28644433087 scopus 로고    scopus 로고
    • Normal huntingtin function: an alternative approach to Huntington's disease
    • Cattaneo E, Zuccato C, Tartari M, (2005) Normal huntingtin function: an alternative approach to Huntington's disease. Nature reviews Neuroscience 6: 919-930.
    • (2005) Nature Reviews Neuroscience , vol.6 , pp. 919-930
    • Cattaneo, E.1    Zuccato, C.2    Tartari, M.3
  • 7
    • 0033757718 scopus 로고    scopus 로고
    • Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice
    • Dragatsis I, Levine MS, Zeitlin S, (2000) Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice. Nature genetics 26: 300-306.
    • (2000) Nature Genetics , vol.26 , pp. 300-306
    • Dragatsis, I.1    Levine, M.S.2    Zeitlin, S.3
  • 8
    • 0029055717 scopus 로고
    • Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes
    • Nasir J, Floresco SB, O'Kusky JR, Diewert VM, Richman JM, et al. (1995) Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes. Cell 81: 811-823.
    • (1995) Cell , vol.81 , pp. 811-823
    • Nasir, J.1    Floresco, S.B.2    O'Kusky, J.R.3    Diewert, V.M.4    Richman, J.M.5
  • 9
    • 84993912315 scopus 로고
    • Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
    • Zeitlin S, Liu JP, Chapman DL, Papaioannou VE, Efstratiadis A, (1995) Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue. Nature genetics 11: 155-163.
    • (1995) Nature Genetics , vol.11 , pp. 155-163
    • Zeitlin, S.1    Liu, J.P.2    Chapman, D.L.3    Papaioannou, V.E.4    Efstratiadis, A.5
  • 10
  • 11
    • 24944547022 scopus 로고    scopus 로고
    • Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo
    • Woda JM, Calzonetti T, Hilditch-Maguire P, Duyao MP, Conlon RA, et al. (2005) Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo. BMC developmental biology 5: 17.
    • (2005) BMC Developmental Biology , vol.5 , pp. 17
    • Woda, J.M.1    Calzonetti, T.2    Hilditch-Maguire, P.3    Duyao, M.P.4    Conlon, R.A.5
  • 12
    • 0030613177 scopus 로고    scopus 로고
    • Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion
    • White JK, Auerbach W, Duyao MP, Vonsattel JP, Gusella JF, et al. (1997) Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion. Nature genetics 17: 404-410.
    • (1997) Nature Genetics , vol.17 , pp. 404-410
    • White, J.K.1    Auerbach, W.2    Duyao, M.P.3    Vonsattel, J.P.4    Gusella, J.F.5
  • 16
    • 17044375442 scopus 로고    scopus 로고
    • The distribution of progenitor cells in the subependymal layer of the lateral ventricle in the normal and Huntington's disease human brain
    • Curtis MA, Penney EB, Pearson J, Dragunow M, Connor B, et al. (2005) The distribution of progenitor cells in the subependymal layer of the lateral ventricle in the normal and Huntington's disease human brain. Neuroscience 132: 777-788.
    • (2005) Neuroscience , vol.132 , pp. 777-788
    • Curtis, M.A.1    Penney, E.B.2    Pearson, J.3    Dragunow, M.4    Connor, B.5
  • 17
    • 84868507542 scopus 로고    scopus 로고
    • Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death
    • Conforti P, Camnasio S, Mutti C, Valenza M, Thompson M, et al. (2013) Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death. Neurobiol Dis 50: 160-170.
    • (2013) Neurobiol Dis , vol.50 , pp. 160-170
    • Conforti, P.1    Camnasio, S.2    Mutti, C.3    Valenza, M.4    Thompson, M.5
  • 18
    • 77958192164 scopus 로고    scopus 로고
    • Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease
    • Milnerwood AJ, Raymond LA, (2010) Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease. Trends in neurosciences 33: 513-523.
    • (2010) Trends in Neurosciences , vol.33 , pp. 513-523
    • Milnerwood, A.J.1    Raymond, L.A.2
  • 24
    • 0035943144 scopus 로고    scopus 로고
    • Psychiatric symptoms and CAG repeats in neurologically asymptomatic Huntington's disease gene carriers
    • Berrios GE, Wagle AC, Markova IS, Wagle SA, Ho LW, et al. (2001) Psychiatric symptoms and CAG repeats in neurologically asymptomatic Huntington's disease gene carriers. Psychiatry Res. 102(3): 217-25.
    • (2001) Psychiatry Res , vol.102 , Issue.3 , pp. 217-225
    • Berrios, G.E.1    Wagle, A.C.2    Markova, I.S.3    Wagle, S.A.4    Ho, L.W.5
  • 26
    • 0038476184 scopus 로고    scopus 로고
    • Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis
    • Rosas HD, Koroshetz WJ, Chen YI, Skeuse C, Vangel M, et al. (2003) Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis. Neurology 60: 1615-1620.
    • (2003) Neurology , vol.60 , pp. 1615-1620
    • Rosas, H.D.1    Koroshetz, W.J.2    Chen, Y.I.3    Skeuse, C.4    Vangel, M.5
  • 27
    • 1042276562 scopus 로고    scopus 로고
    • Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis
    • author reply 524
    • Kassubek J, Gaus W, Landwehrmeyer GB (2004) Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis. Neurology 62: 523-524; author reply 524.
    • (2004) Neurology , vol.62 , pp. 523-524
    • Kassubek, J.1    Gaus, W.2    Landwehrmeyer, G.B.3
  • 28
    • 29944443025 scopus 로고    scopus 로고
    • Embryonic stem cells assume a primitive neural stem cell fate in the absence of extrinsic influences
    • Smukler SR, Runciman SB, Xu S, van der Kooy D, (2006) Embryonic stem cells assume a primitive neural stem cell fate in the absence of extrinsic influences. The Journal of cell biology 172: 79-90.
    • (2006) The Journal of Cell Biology , vol.172 , pp. 79-90
    • Smukler, S.R.1    Runciman, S.B.2    Xu, S.3    van der Kooy, D.4
  • 29
    • 0035025619 scopus 로고    scopus 로고
    • Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism
    • Tropepe V, Hitoshi S, Sirard C, Mak TW, Rossant J, et al. (2001) Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism. Neuron 30: 65-78.
    • (2001) Neuron , vol.30 , pp. 65-78
    • Tropepe, V.1    Hitoshi, S.2    Sirard, C.3    Mak, T.W.4    Rossant, J.5
  • 30
    • 0034163497 scopus 로고    scopus 로고
    • Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice
    • Wheeler VC, White JK, Gutekunst CA, Vrbanac V, Weaver M, et al. (2000) Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice. Hum mol genet. 9(4): 503-513.
    • (2000) Hum mol genet , vol.9 , Issue.4 , pp. 503-513
    • Wheeler, V.C.1    White, J.K.2    Gutekunst, C.A.3    Vrbanac, V.4    Weaver, M.5
  • 31
    • 1642445643 scopus 로고    scopus 로고
    • Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon
    • Tropepe V, Sibilia M, Ciruna BG, Rossant J, Wagner EF, et al. (1999) Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Developmental biology 208: 166-.
    • (1999) Developmental biology , vol.20 , pp. 166
    • Tropepe, V.1    Sibilia, M.2    Ciruna, B.G.3    Rossant, J.4    Wagner, E.F.5
  • 32
    • 0036205049 scopus 로고    scopus 로고
    • Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells
    • Hitoshi S, Alexson T, Tropepe V, Donoviel D, Elia AJ, et al. (2002) Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. Genes & development 16: 846-858.
    • (2002) Genes & Development , vol.16 , pp. 846-858
    • Hitoshi, S.1    Alexson, T.2    Tropepe, V.3    Donoviel, D.4    Elia, A.J.5
  • 33
    • 3543086157 scopus 로고    scopus 로고
    • Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling
    • Hitoshi S, Seaberg RM, Koscik C, Alexson T, Kusunoki S, et al. (2004) Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling. Genes & development 18: 1806-1811.
    • (2004) Genes & Development , vol.18 , pp. 1806-1811
    • Hitoshi, S.1    Seaberg, R.M.2    Koscik, C.3    Alexson, T.4    Kusunoki, S.5
  • 34
    • 0035512348 scopus 로고    scopus 로고
    • Neural induction: toward a unifying mechanism
    • Wilson SI, Edlund T, (2001) Neural induction: toward a unifying mechanism. Nat Neurosci 4Suppl: 1161-1168.
    • (2001) Nat Neurosci , vol.4
    • Wilson, S.I.1    Edlund, T.2
  • 35
    • 34547700773 scopus 로고    scopus 로고
    • Proposal of a model of mammalian neural induction
    • Levine AJ, Brivanlou AH, (2007) Proposal of a model of mammalian neural induction. Developmental biology 308: 247-256.
    • (2007) Developmental Biology , vol.308 , pp. 247-256
    • Levine, A.J.1    Brivanlou, A.H.2
  • 36
    • 0000790724 scopus 로고    scopus 로고
    • SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes
    • Liu YF, Deth RC, Devys D, (1997) SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes. The Journal of biological chemistry 272: 8121-8124.
    • (1997) The Journal of Biological Chemistry , vol.272 , pp. 8121-8124
    • Liu, Y.F.1    Deth, R.C.2    Devys, D.3
  • 37
    • 0032512588 scopus 로고    scopus 로고
    • Novel recruitment of Shc, Grb2, and Sos by fibroblast growth factor receptor-1 in v-Src-transformed cells
    • Curto M, Frankel P, Carrero A, Foster DA, (1998) Novel recruitment of Shc, Grb2, and Sos by fibroblast growth factor receptor-1 in v-Src-transformed cells. Biochem Biophys Res Commun 243: 555-560.
    • (1998) Biochem Biophys Res Commun , vol.243 , pp. 555-560
    • Curto, M.1    Frankel, P.2    Carrero, A.3    Foster, D.A.4
  • 38
    • 41549140462 scopus 로고    scopus 로고
    • Oscillations in notch signaling regulate maintenance of neural progenitors
    • Shimojo H, Ohtsuka T, Kageyama R, (2008) Oscillations in notch signaling regulate maintenance of neural progenitors. Neuron 58: 52-64.
    • (2008) Neuron , vol.58 , pp. 52-64
    • Shimojo, H.1    Ohtsuka, T.2    Kageyama, R.3
  • 40
    • 69249215528 scopus 로고    scopus 로고
    • The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells
    • Kobayashi T, Mizuno H, Imayoshi I, Furusawa C, Shirahige K, et al. (2009) The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells. Genes & development 23: 1870-1875.
    • (2009) Genes & Development , vol.23 , pp. 1870-1875
    • Kobayashi, T.1    Mizuno, H.2    Imayoshi, I.3    Furusawa, C.4    Shirahige, K.5
  • 41
    • 33646726733 scopus 로고    scopus 로고
    • Notch promotes neural lineage entry by pluripotent embryonic stem cells
    • Lowell S, Benchoua A, Heavey B, Smith AG, (2006) Notch promotes neural lineage entry by pluripotent embryonic stem cells. PLoS biology 4: e121.
    • (2006) PLoS Biology , vol.4
    • Lowell, S.1    Benchoua, A.2    Heavey, B.3    Smith, A.G.4
  • 42
    • 47849122005 scopus 로고    scopus 로고
    • Huntingtin interacting protein 1 can regulate neurogenesis in Drosophila
    • Moores JN, Roy S, Nicholson DW, Staveley BE, (2008) Huntingtin interacting protein 1 can regulate neurogenesis in Drosophila. Eur J Neurosci 28(3): 599-609.
    • (2008) Eur J Neurosci , vol.28 , Issue.3 , pp. 599-609
    • Moores, J.N.1    Roy, S.2    Nicholson, D.W.3    Staveley, B.E.4
  • 43
    • 0041353535 scopus 로고    scopus 로고
    • Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
    • Zuccato C, Tartari M, Crotti A, Goffredo D, Valenza M, et al. (2003) Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nature genetics 35: 76-83.
    • (2003) Nature Genetics , vol.35 , pp. 76-83
    • Zuccato, C.1    Tartari, M.2    Crotti, A.3    Goffredo, D.4    Valenza, M.5
  • 44
    • 73349091835 scopus 로고    scopus 로고
    • Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance
    • Yamada Y, Aoki H, Kunisada T, Hara A, (2010) Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance. Cell stem cell 6: 10-15.
    • (2010) Cell Stem Cell , vol.6 , pp. 10-15
    • Yamada, Y.1    Aoki, H.2    Kunisada, T.3    Hara, A.4
  • 47
    • 10344264425 scopus 로고    scopus 로고
    • Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation
    • Hatakeyama J, Bessho Y, Katoh K, Ookawara S, Fujioka M, et al. (2004) Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation. Development 131: 5539-5550.
    • (2004) Development , vol.131 , pp. 5539-5550
    • Hatakeyama, J.1    Bessho, Y.2    Katoh, K.3    Ookawara, S.4    Fujioka, M.5
  • 48
    • 33847181714 scopus 로고    scopus 로고
    • Identification of self-replicating multipotent progenitors in the embryonic nervous system by high Notch activity and Hes5 expression
    • Basak O, Taylor V, (2007) Identification of self-replicating multipotent progenitors in the embryonic nervous system by high Notch activity and Hes5 expression. The European journal of neuroscience 25: 1006-1022.
    • (2007) The European Journal of Neuroscience , vol.25 , pp. 1006-1022
    • Basak, O.1    Taylor, V.2
  • 49
    • 33746843250 scopus 로고    scopus 로고
    • Notch1 expression is spatiotemporally correlated with neurogenesis and negatively regulated by Notch1-independent Hes genes in the developing nervous system
    • Hatakeyama J, Kageyama R, (2006) Notch1 expression is spatiotemporally correlated with neurogenesis and negatively regulated by Notch1-independent Hes genes in the developing nervous system. Cerebral cortex 16Suppl 1: i132-137.
    • (2006) Cerebral Cortex , vol.16
    • Hatakeyama, J.1    Kageyama, R.2
  • 50
    • 33745600820 scopus 로고    scopus 로고
    • Asymmetric and symmetric stem-cell divisions in development and cancer
    • Morrison SJ, Kimble J, (2006) Asymmetric and symmetric stem-cell divisions in development and cancer. Nature 441: 1068-1074.
    • (2006) Nature , vol.441 , pp. 1068-1074
    • Morrison, S.J.1    Kimble, J.2
  • 51
    • 79851509663 scopus 로고    scopus 로고
    • Hes1 functions downstream of growth factors to maintain oligodendrocyte lineage cells in the early progenitor stage
    • Ogata T, Ueno T, Hoshikawa S, Ito J, Okazaki R, et al. (2011) Hes1 functions downstream of growth factors to maintain oligodendrocyte lineage cells in the early progenitor stage. Neuroscience 176: 132-141.
    • (2011) Neuroscience , vol.176 , pp. 132-141
    • Ogata, T.1    Ueno, T.2    Hoshikawa, S.3    Ito, J.4    Okazaki, R.5
  • 53
    • 27544466232 scopus 로고    scopus 로고
    • Notch signaling coordinates the patterning of striatal compartments
    • Mason HA, Rakowiecki SM, Raftopoulou M, Nery S, Huang Y, et al. (2005) Notch signaling coordinates the patterning of striatal compartments. Development 132: 4247-4258.
    • (2005) Development , vol.132 , pp. 4247-4258
    • Mason, H.A.1    Rakowiecki, S.M.2    Raftopoulou, M.3    Nery, S.4    Huang, Y.5
  • 54
    • 57149122292 scopus 로고    scopus 로고
    • Expanded CAG repeats in the murine Huntington's disease gene increases neuronal differentiation of embryonic and neural stem cells
    • Lorincz MT, Zawistowski VA, (2009) Expanded CAG repeats in the murine Huntington's disease gene increases neuronal differentiation of embryonic and neural stem cells. Molecular and cellular neurosciences 40: 1-13.
    • (2009) Molecular and Cellular Neurosciences , vol.40 , pp. 1-13
    • Lorincz, M.T.1    Zawistowski, V.A.2
  • 55
    • 0034641887 scopus 로고    scopus 로고
    • Dramatic mutation instability in HD mouse striatum: does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease?
    • Kennedy L, Shelbourne PF, (2000) Dramatic mutation instability in HD mouse striatum: does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease? Hum Mol Genet 9: 2539-2544.
    • (2000) Hum Mol Genet , vol.9 , pp. 2539-2544
    • Kennedy, L.1    Shelbourne, P.F.2
  • 56
    • 74249102052 scopus 로고    scopus 로고
    • Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice
    • Goula AV, Berquist BR, Wilson DM, 3rd, Wheeler VC, Trottier Y, et al (2009) Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice. PLoS genetics 5: e1000749.
    • (2009) PLoS Genetics , vol.5
    • Goula, A.V.1    Berquist, B.R.2    Wilson 3rd, D.M.3    Wheeler, V.C.4    Trottier, Y.5
  • 57
    • 0346752132 scopus 로고    scopus 로고
    • Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis
    • Kennedy L, Evans E, Chen CM, Craven L, Detloff PJ, et al. (2003) Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis. Hum Mol Genet 12: 3359-3367.
    • (2003) Hum Mol Genet , vol.12 , pp. 3359-3367
    • Kennedy, L.1    Evans, E.2    Chen, C.M.3    Craven, L.4    Detloff, P.J.5
  • 58
    • 77955643169 scopus 로고    scopus 로고
    • Molecular mechanisms and potential therapeutical targets in Huntington's disease
    • Zuccato C, Valenza M, Cattaneo E, (2010) Molecular mechanisms and potential therapeutical targets in Huntington's disease. Physiological reviews 90: 905-981.
    • (2010) Physiological Reviews , vol.90 , pp. 905-981
    • Zuccato, C.1    Valenza, M.2    Cattaneo, E.3
  • 59
    • 84866111172 scopus 로고    scopus 로고
    • Development and neurodegeneration: turning HD pathogenesis on its head
    • Marder K, Mehler MF, (2012) Development and neurodegeneration: turning HD pathogenesis on its head. Neurology 79: 621-622.
    • (2012) Neurology , vol.79 , pp. 621-622
    • Marder, K.1    Mehler, M.F.2
  • 61
    • 80054904670 scopus 로고    scopus 로고
    • Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years
    • Braak H, Thal DR, Ghebremedhin E, Del Tredici K, (2011) Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years. J Neuropathol Exp Neurol 70: 960-969.
    • (2011) J Neuropathol Exp Neurol , vol.70 , pp. 960-969
    • Braak, H.1    Thal, D.R.2    Ghebremedhin, E.3    Del Tredici, K.4
  • 62
    • 57049182374 scopus 로고    scopus 로고
    • Neuroanatomy and pathology of sporadic Parkinson's disease
    • Braak H, Del Tredici K, (2009) Neuroanatomy and pathology of sporadic Parkinson's disease. Adv Anat Embryol Cell Biol 201: 1-119.
    • (2009) Adv Anat Embryol Cell Biol , vol.201 , pp. 1-119
    • Braak, H.1    Del Tredici, K.2
  • 64
    • 70449578270 scopus 로고    scopus 로고
    • Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation
    • Abrajano JJ, Qureshi IA, Gokhan S, Zheng D, Bergman A, et al. (2009) Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation. PloS one 4: e7665.
    • (2009) PloS One , vol.4
    • Abrajano, J.J.1    Qureshi, I.A.2    Gokhan, S.3    Zheng, D.4    Bergman, A.5
  • 65
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 66
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
    • Pfaffl MW, Horgan GW, Dempfle L, (2002) Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30: e36.
    • (2002) Nucleic Acids Res , vol.30
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.