Myristate-derived d16:0 sphingolipids constitute a cardiac sphingolipid pool with distinct synthetic routes and functional properties

Journal of Biological Chemistry

Volumn 288, Issue 19, 2013, Pages 13397-13409

  Russo, Sarah Brice ^a   Tidhar, Rotem ^b   Futerman, Anthony H ^b   Cowart, L Ashley ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

FUNCTIONAL PROPERTIES; MYOCARDIAL PATHOLOGY; NON-REDUNDANT; POTENTIAL SUBSTRATE; SPHINGOID BASIS; SPHINGOLIPIDS; SYNTHETIC ROUTES;

COPYRIGHTS; LAKES;

LIPIDS;

DIHYDROCERAMIDE; MYRISTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PALMITIC ACID; PROTEIN SPTLC3; SERINE PALMITOYLTRANSFERASE; SPHINGANINE; SPHINGOLIPID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CAT; CATALYSIS; CONTROLLED STUDY; DERIVATIZATION; ENZYME ACTIVITY; HEART MUSCLE; HEART MUSCLE CELL; IN VITRO STUDY; LIPID DIET; LIPID METABOLISM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE;

CARDIAC MUSCLE; CELL METABOLISM; CERAMIDE; CERAMIDE SYNTHASE; HEART; LIPID METABOLISM; OBESITY; SERINE PALMITOYLTRANSFERASE; SPHINGOLIPID;

ACYL COENZYME A; ANIMALS; AUTOPHAGY; BIOSYNTHETIC PATHWAYS; CATS; CELL LINE; CELL SURVIVAL; DIET, HIGH-FAT; GENE EXPRESSION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEART VENTRICLES; ISOENZYMES; KINETICS; LIPID METABOLISM; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; MYOCARDIUM; MYOCYTES, CARDIAC; MYRISTIC ACID; PALMITOYL COENZYME A; RATS; SERINE C-PALMITOYLTRANSFERASE; SPHINGOLIPIDS; SPHINGOSINE N-ACYLTRANSFERASE; SUBSTRATE SPECIFICITY;

EID: 84877721470     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.428185     Document Type: Article

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