Excitotoxicity-induced immediate surge in hippocampal prostanoid production has latent effects that promote chronic progressive neuronal death

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 88, Issue 5, 2013, Pages 373-381

  Yoshikawa, Keisuke ^a,b   Kita, Yoshihiro ^c   Furukawa, Ayako ^a   Kawamura, Noriko ^a   Hasegawa Ishii, Sanae ^a   Chiba, Yoichi ^a   Takei, Shiro ^a   Maruyama, Kei ^b   Shimizu, Takao ^c,d   Shimada, Atsuyoshi ^a  

^a INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

Excitotoxicity; Kainic acid; Neuronal death; Prostaglandin; Seizure

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; APOPTOSIS INDUCING FACTOR; CALCIUM BINDING PROTEIN; GLUTAMATE AMMONIA LIGASE; INDOMETACIN; KAINIC ACID; PROSTAGLANDIN D2; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTANOID; THROMBOXANE B2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ATROPHY; BRAIN SIZE; CELL ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE SEVERITY; EXCITOTOXICITY; HIPPOCAMPUS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; RAT;

ANIMALS; CELL DEATH; HIPPOCAMPUS; KAINIC ACID; MALE; MICROGLIA; NERVE DEGENERATION; NEURONS; PROSTAGLANDINS; RATS; RATS, WISTAR;

RATTUS;

EID: 84877614292     PISSN: 09523278     EISSN: 15322823     Source Type: Journal    
DOI: 10.1016/j.plefa.2013.02.007     Document Type: Article

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