Effects of SC58236, a selective COX-2 inhibitor, on epileptogenesis and spontaneous seizures in a rat model for temporal lobe epilepsy

Epilepsy Research

Volumn 84, Issue 1, 2009, Pages 56-66

  Holtman, L ^a   van Vliet, E A ^a,c   van Schaik, R ^a   Queiroz, C M ^a   Aronica, E ^b,c   Gorter, J A ^a,c  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c STICHTING EPILEPSIE INSTELLINGEN NEDERLAND SEIN   (Netherlands)

Author keywords

Anti inflammatory; EEG; Human; Immunocytochemistry; In vivo; Prostaglandin; Seizures; Status epilepticus

Indexed keywords

4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; CYCLOOXYGENASE 2 INHIBITOR; NEURON SPECIFIC NUCLEAR PROTEIN; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOLOGICAL MONITORING; CELL DEATH; CHRONIC DISEASE; CONTROLLED STUDY; DISEASE DURATION; DRUG EFFECT; ELECTROENCEPHALOGRAM; ENZYME INHIBITION; EPILEPTOGENESIS; GENE OVEREXPRESSION; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; LATENT PERIOD; MALE; MICROGLIA; NERVE CELL GROWTH; NISSL STAINING; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS INHIBITION; RAT; SEIZURE; TEMPORAL LOBE EPILEPSY; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE; VIDEORECORDING;

ADOLESCENT; ADULT; ANIMALS; ANTIGENS, CD11B; BRAIN; CELL DEATH; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; ELECTROSHOCK; EPILEPSY, TEMPORAL LOBE; FEMALE; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; PHOSPHOPYRUVATE HYDRATASE; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; SULFONAMIDES; TIME FACTORS; YOUNG ADULT;

EID: 60949104467     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2008.12.006     Document Type: Article

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