Systemic administration of N(ω)-nitro-L-arginine methyl ester and indomethacin reduces the elevation of brain PGE2 content and prevents seizures and hippocampal damage evoked by LiCl and tacrine in rat

Experimental Neurology

Volumn 149, Issue 2, 1998, Pages 349-355

  Paoletti, Anna Maria ^a   Piccirilli, Silvia ^b   Costa, Nicola ^c   Rotiroti, Domenicantonio ^c   Bagetta, Giacinto ^a,d   Nisticò, Giuseppe ^e  

^a Via Ardeatina   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c UNIVERSITY MEDITERRANEA OF REGGIO CALABRIA   (Italy)

^d UNIVERSITY OF CALABRIA   (Italy)

^e UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

COX 2; LiCl; Neurodegeneration; Nitric oxide; PGE2; Seizures; Tacrine

Indexed keywords

ARGININE METHYL ESTER; INDOMETACIN; LITHIUM CHLORIDE; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN SYNTHASE; TACRINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTICLE; BRAIN INJURY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; SEIZURE; STEREOCHEMISTRY;

EID: 0032006287     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1997.6741     Document Type: Article

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