Overexpression of human mutated G93A SOD1 changes dynamics of the ER mitochondria calcium cycle specifically in mouse embryonic motor neurons

Experimental Neurology

Volumn 247, Issue , 2013, Pages 91-100

  Lautenschläger, Janin ^a   Prell, Tino ^a   Ruhmer, Julia ^a   Weidemann, Lisa ^a   Witte, Otto W ^a   Grosskreutz, Julian ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

Author keywords

Amyotrophic lateral sclerosis; Calcium; ER; Mitochondria; Motor neuron

Indexed keywords

CALCIUM; CALCIUM BINDING PROTEIN; COPPER ZINC SUPEROXIDE DISMUTASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM CALCIUM EXCHANGE PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM; EXCITOTOXICITY; FEMALE; FLUORESCENCE ANALYSIS; GENE MUTATION; MALE; MITOCHONDRION; MOTONEURON; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

Α-AMINO-5-METHYL-3-HYDROXYISOXAZOLONE-4-PROPIONAT; ALS; AMPA; AMYOTROPHIC LATERAL SCLEROSIS; CABP; CALCIUM; CALCIUM BINDING PROTEINS; CPA; CSA; CYCLOPIAZONIC ACID; CYCLOSPORINE A; EARTH MOVER'S DISTANCE; EIF2Α; EMD; ER; ER MITOCHONDRIA CALCIUM CYCLE; ERMCC; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 Α; FUS/TLS; FUSED IN SARCOMA/TRANSLATED IN LIPOSARCOMA; HSOD1; HUMAN SUPEROXIDE DISMUTASE 1; MITOCHONDRIA; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOCHONDRIAL SODIUM CALCIUM EXCHANGER; MITOCHONDRIAL UNIPORTER; MNCE; MOTOR NEURON; MPTP; MUP; SARCO-/ENDOPLASMIC RETICULUM ATPASE; SERCA; TDP-43; TETRODOTOXIN; TRANSACTIVE RESPONSE (TAR) DNA-BINDING PROTEIN-43; TTX; UNFOLDED PROTEIN RESPONSE; UPR; VALOSIN CONTAINING PROTEIN; VAPB; VCP; VESICLE-ASSOCIATED MEMBRANE PROTEIN (VAMP)-ASSOCIATED PROTEIN B; VGCC; VOLTAGE GATED CALCIUM CHANNELS; X-BOX BINDING PROTEIN 1; XBP1;

ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CELLS, CULTURED; CLONAZEPAM; EMBRYO, MAMMALIAN; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; INDOLES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; MOTOR NEURONS; RUTHENIUM COMPOUNDS; SODIUM CHANNEL BLOCKERS; SPINAL CORD; SUPEROXIDE DISMUTASE; TETRODOTOXIN; THIAZEPINES; UNFOLDED PROTEIN RESPONSE; VERAPAMIL;

EID: 84877352746     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.03.027     Document Type: Article

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