메뉴 건너뛰기




Volumn 244, Issue , 2013, Pages 16-30

The regulatory role of NF-κB in autophagy-like cell death after focal cerebral ischemia in mice

Author keywords

Akt, the mammalian target of rapamycin (mTOR); Autophagy; Blood brain barrier; Cerebral ischemia; Neurovascular unit; NF kappaB

Indexed keywords

3 METHYLADENINE; BECLIN 1; BRAIN PROTEIN; COLLAGEN TYPE 4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; NEURON SPECIFIC NUCLEAR PROTEIN; OCCLUDIN; POTEIN LC3; PROTEIN KINASE B; PROTEIN P50; UNCLASSIFIED DRUG;

EID: 84877342681     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.03.045     Document Type: Article
Times cited : (80)

References (56)
  • 2
    • 33846226521 scopus 로고    scopus 로고
    • The roles of autophagy in cerebral ischemia
    • Adhami F., Schloemer A., Kuan C.Y. The roles of autophagy in cerebral ischemia. Autophagy 2007, 3:42-44.
    • (2007) Autophagy , vol.3 , pp. 42-44
    • Adhami, F.1    Schloemer, A.2    Kuan, C.Y.3
  • 3
    • 26944463905 scopus 로고    scopus 로고
    • Standard deviations and standard errors
    • Altman D.G., Bland J.M. Standard deviations and standard errors. BMJ 2005, 331:903.
    • (2005) BMJ , vol.331 , pp. 903
    • Altman, D.G.1    Bland, J.M.2
  • 4
    • 61649124034 scopus 로고    scopus 로고
    • Autophagy in hypoxia-ischemia induced brain injury: evidence and speculations
    • Balduini W., Carloni S., Buonocore G. Autophagy in hypoxia-ischemia induced brain injury: evidence and speculations. Autophagy 2009, 5:221-223.
    • (2009) Autophagy , vol.5 , pp. 221-223
    • Balduini, W.1    Carloni, S.2    Buonocore, G.3
  • 6
    • 84863212730 scopus 로고    scopus 로고
    • A novel stroke therapy of pharmacologically induced hypothermia after focal cerebral ischemia in mice
    • Choi K.E., Hall C.L., Sun J.M., Wei L., Mohamad O., Dix T.A., Yu S.P. A novel stroke therapy of pharmacologically induced hypothermia after focal cerebral ischemia in mice. FASEB J 2012, 26:2799-2810.
    • (2012) FASEB J , vol.26 , pp. 2799-2810
    • Choi, K.E.1    Hall, C.L.2    Sun, J.M.3    Wei, L.4    Mohamad, O.5    Dix, T.A.6    Yu, S.P.7
  • 7
    • 33750060064 scopus 로고    scopus 로고
    • Cellular mechanisms of the protective effect of polyphenols on the neurovascular unit in strokes
    • Curin Y., Ritz M.F., Andriantsitohaina R. Cellular mechanisms of the protective effect of polyphenols on the neurovascular unit in strokes. Cardiovasc Hematol Agents Med Chem 2006, 4:277-288.
    • (2006) Cardiovasc Hematol Agents Med Chem , vol.4 , pp. 277-288
    • Curin, Y.1    Ritz, M.F.2    Andriantsitohaina, R.3
  • 11
    • 33646558596 scopus 로고    scopus 로고
    • NF-kappaB protects neurons from ischemic injury after middle cerebral artery occlusion in mice
    • Duckworth E.A., Butler T., Collier L., Collier S., Pennypacker K.R. NF-kappaB protects neurons from ischemic injury after middle cerebral artery occlusion in mice. Brain Res 2006, 1088:167-175.
    • (2006) Brain Res , vol.1088 , pp. 167-175
    • Duckworth, E.A.1    Butler, T.2    Collier, L.3    Collier, S.4    Pennypacker, K.R.5
  • 12
    • 26844531363 scopus 로고    scopus 로고
    • Maturation of autophagic vacuoles in Mammalian cells
    • Eskelinen E.L. Maturation of autophagic vacuoles in Mammalian cells. Autophagy 2005, 1:1-10.
    • (2005) Autophagy , vol.1 , pp. 1-10
    • Eskelinen, E.L.1
  • 15
    • 74449090257 scopus 로고    scopus 로고
    • Intracellular mechanisms of N-acylethanolamine-mediated neuroprotection in a rat model of stroke
    • Garg P., Duncan R.S., Kaja S., Koulen P. Intracellular mechanisms of N-acylethanolamine-mediated neuroprotection in a rat model of stroke. Neuroscience 2010, 166:252-262.
    • (2010) Neuroscience , vol.166 , pp. 252-262
    • Garg, P.1    Duncan, R.S.2    Kaja, S.3    Koulen, P.4
  • 16
    • 33751348056 scopus 로고    scopus 로고
    • Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1
    • Guertin D.A., Stevens D.M., Thoreen C.C., Burds A.A., Kalaany N.Y., Moffat J., Brown M., Fitzgerald K.J., Sabatini D.M. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. Dev Cell 2006, 11:859-871.
    • (2006) Dev Cell , vol.11 , pp. 859-871
    • Guertin, D.A.1    Stevens, D.M.2    Thoreen, C.C.3    Burds, A.A.4    Kalaany, N.Y.5    Moffat, J.6    Brown, M.7    Fitzgerald, K.J.8    Sabatini, D.M.9
  • 17
    • 33846531305 scopus 로고    scopus 로고
    • The interplay between pro-death and pro-survival signaling pathways in myocardial ischemia/reperfusion injury: apoptosis meets autophagy
    • Hamacher-Brady A., Brady N.R., Gottlieb R.A. The interplay between pro-death and pro-survival signaling pathways in myocardial ischemia/reperfusion injury: apoptosis meets autophagy. Cardiovasc Drugs Ther 2006, 20:445-462.
    • (2006) Cardiovasc Drugs Ther , vol.20 , pp. 445-462
    • Hamacher-Brady, A.1    Brady, N.R.2    Gottlieb, R.A.3
  • 18
    • 29044445105 scopus 로고    scopus 로고
    • The function and integrity of the neurovascular unit rests upon the integration of the vascular and inflammatory cell systems
    • Han H.S., Suk K. The function and integrity of the neurovascular unit rests upon the integration of the vascular and inflammatory cell systems. Curr Neurovasc Res 2005, 2:409-423.
    • (2005) Curr Neurovasc Res , vol.2 , pp. 409-423
    • Han, H.S.1    Suk, K.2
  • 19
    • 78149259667 scopus 로고    scopus 로고
    • NF-kappaB and innate immunity in ischemic stroke
    • Harari O.A., Liao J.K. NF-kappaB and innate immunity in ischemic stroke. Ann N Y Acad Sci 2010, 1207:32-40.
    • (2010) Ann N Y Acad Sci , vol.1207 , pp. 32-40
    • Harari, O.A.1    Liao, J.K.2
  • 22
    • 25144506835 scopus 로고    scopus 로고
    • Autophagy in cell death: an innocent convict?
    • Levine B., Yuan J. Autophagy in cell death: an innocent convict?. J Clin Invest 2005, 115:2679-2688.
    • (2005) J Clin Invest , vol.115 , pp. 2679-2688
    • Levine, B.1    Yuan, J.2
  • 23
    • 35848955690 scopus 로고    scopus 로고
    • Erythropoietin prevents blood-brain barrier damage induced by focal cerebral ischemia in mice
    • Li Y., Lu Z.Y., Ogle M., Wei L. Erythropoietin prevents blood-brain barrier damage induced by focal cerebral ischemia in mice. Neurochem Res 2007, 32:2132-2141.
    • (2007) Neurochem Res , vol.32 , pp. 2132-2141
    • Li, Y.1    Lu, Z.Y.2    Ogle, M.3    Wei, L.4
  • 24
    • 54049097850 scopus 로고    scopus 로고
    • Cell death and proliferation in NF-kappaB p50 knockout mouse after cerebral ischemia
    • Li J., Lu Z., Li W.L., Yu S.P., Wei L. Cell death and proliferation in NF-kappaB p50 knockout mouse after cerebral ischemia. Brain Res 2008, 1230:281-289.
    • (2008) Brain Res , vol.1230 , pp. 281-289
    • Li, J.1    Lu, Z.2    Li, W.L.3    Yu, S.P.4    Wei, L.5
  • 25
    • 55249109547 scopus 로고    scopus 로고
    • Enhanced neurogenesis and cell migration following focal ischemia and peripheral stimulation in mice
    • Li W.L., Yu S.P., Ogle M.E., Ding X.S., Wei L. Enhanced neurogenesis and cell migration following focal ischemia and peripheral stimulation in mice. Dev Neurobiol 2008, 68:1474-1486.
    • (2008) Dev Neurobiol , vol.68 , pp. 1474-1486
    • Li, W.L.1    Yu, S.P.2    Ogle, M.E.3    Ding, X.S.4    Wei, L.5
  • 26
    • 85052609749 scopus 로고    scopus 로고
    • Erythropoietin attenuates intracerebral hemorrhage by diminishing matrix metalloproteinases and maintaining blood-brain barrier integrity in mice
    • Li Y., Ogle M.E., Wallace G.C., Lu Z.Y., Yu S.P., Wei L. Erythropoietin attenuates intracerebral hemorrhage by diminishing matrix metalloproteinases and maintaining blood-brain barrier integrity in mice. Acta Neurochir Suppl 2008, 105:105-112.
    • (2008) Acta Neurochir Suppl , vol.105 , pp. 105-112
    • Li, Y.1    Ogle, M.E.2    Wallace, G.C.3    Lu, Z.Y.4    Yu, S.P.5    Wei, L.6
  • 27
    • 33646156398 scopus 로고    scopus 로고
    • Age-related neural degeneration in nuclear-factor kappaB p50 knockout mice
    • Lu Z.Y., Yu S.P., Wei J.F., Wei L. Age-related neural degeneration in nuclear-factor kappaB p50 knockout mice. Neuroscience 2006, 139:965-978.
    • (2006) Neuroscience , vol.139 , pp. 965-978
    • Lu, Z.Y.1    Yu, S.P.2    Wei, J.F.3    Wei, L.4
  • 29
    • 43949109275 scopus 로고    scopus 로고
    • Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle
    • Mammucari C., Schiaffino S., Sandri M. Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle. Autophagy 2008, 4:524-526.
    • (2008) Autophagy , vol.4 , pp. 524-526
    • Mammucari, C.1    Schiaffino, S.2    Sandri, M.3
  • 30
    • 33644606050 scopus 로고    scopus 로고
    • Detection of autophagy in tissue by standard immunohistochemistry: possibilities and limitations
    • Martinet W., De Meyer G.R., Andries L., Herman A.G., Kockx M.M. Detection of autophagy in tissue by standard immunohistochemistry: possibilities and limitations. Autophagy 2006, 2:55-57.
    • (2006) Autophagy , vol.2 , pp. 55-57
    • Martinet, W.1    De Meyer, G.R.2    Andries, L.3    Herman, A.G.4    Kockx, M.M.5
  • 31
    • 77950228925 scopus 로고    scopus 로고
    • Autophagy in health and disease. 1. Regulation and significance of autophagy: an overview
    • Mehrpour M., Esclatine A., Beau I., Codogno P. Autophagy in health and disease. 1. Regulation and significance of autophagy: an overview. Am J Physiol Cell Physiol 2010, 298:C776-785.
    • (2010) Am J Physiol Cell Physiol , vol.298
    • Mehrpour, M.1    Esclatine, A.2    Beau, I.3    Codogno, P.4
  • 32
    • 57649170809 scopus 로고    scopus 로고
    • Post-ischemic brain damage: targeting PARP-1 within the ischemic neurovascular units as a realistic avenue to stroke treatment
    • Moroni F., Chiarugi A. Post-ischemic brain damage: targeting PARP-1 within the ischemic neurovascular units as a realistic avenue to stroke treatment. FEBS J 2009, 276:36-45.
    • (2009) FEBS J , vol.276 , pp. 36-45
    • Moroni, F.1    Chiarugi, A.2
  • 35
    • 33747368249 scopus 로고    scopus 로고
    • Blood-brain barrier: structural components and function under physiologic and pathologic conditions
    • Persidsky Y., Ramirez S.H., Haorah J., Kanmogne G.D. Blood-brain barrier: structural components and function under physiologic and pathologic conditions. J Neuroimmune Pharmacol 2006, 1:223-236.
    • (2006) J Neuroimmune Pharmacol , vol.1 , pp. 223-236
    • Persidsky, Y.1    Ramirez, S.H.2    Haorah, J.3    Kanmogne, G.D.4
  • 36
    • 33747284324 scopus 로고    scopus 로고
    • Distinct roles of diverse nuclear factor-kappaB complexes in neuropathological mechanisms
    • Pizzi M., Spano P. Distinct roles of diverse nuclear factor-kappaB complexes in neuropathological mechanisms. Eur J Pharmacol 2006, 545:22-28.
    • (2006) Eur J Pharmacol , vol.545 , pp. 22-28
    • Pizzi, M.1    Spano, P.2
  • 37
    • 70350059677 scopus 로고    scopus 로고
    • Postischemic treatment of neonatal cerebral ischemia should target autophagy
    • Puyal J., Vaslin A., Mottier V., Clarke P.G. Postischemic treatment of neonatal cerebral ischemia should target autophagy. Ann Neurol 2009, 66:378-389.
    • (2009) Ann Neurol , vol.66 , pp. 378-389
    • Puyal, J.1    Vaslin, A.2    Mottier, V.3    Clarke, P.G.4
  • 38
    • 36549041882 scopus 로고    scopus 로고
    • Focal cerebral ischemia induces upregulation of Beclin 1 and autophagy-like cell death
    • Rami A., Langhagen A., Steiger S. Focal cerebral ischemia induces upregulation of Beclin 1 and autophagy-like cell death. Neurobiol Dis 2008, 29:132-141.
    • (2008) Neurobiol Dis , vol.29 , pp. 132-141
    • Rami, A.1    Langhagen, A.2    Steiger, S.3
  • 40
    • 77956266130 scopus 로고    scopus 로고
    • Statistics in experimental cerebrovascular research: comparison of more than two groups with a continuous outcome variable
    • Schlattmann P., Dirnagl U. Statistics in experimental cerebrovascular research: comparison of more than two groups with a continuous outcome variable. J Cereb Blood Flow Metab 2010, 30:1558-1563.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 1558-1563
    • Schlattmann, P.1    Dirnagl, U.2
  • 41
    • 38449091923 scopus 로고    scopus 로고
    • The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy
    • Shacka J.J., Roth K.A., Zhang J. The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy. Front Biosci 2008, 13:718-736.
    • (2008) Front Biosci , vol.13 , pp. 718-736
    • Shacka, J.J.1    Roth, K.A.2    Zhang, J.3
  • 42
    • 43949128077 scopus 로고    scopus 로고
    • Molecular regulation of autophagy and apoptosis during ischemic and non-ischemic cardiomyopathy
    • Shaw J., Kirshenbaum L.A. Molecular regulation of autophagy and apoptosis during ischemic and non-ischemic cardiomyopathy. Autophagy 2008, 4:427-434.
    • (2008) Autophagy , vol.4 , pp. 427-434
    • Shaw, J.1    Kirshenbaum, L.A.2
  • 43
    • 8344242220 scopus 로고    scopus 로고
    • Autophagy in health and disease: a double-edged sword
    • Shintani T., Klionsky D.J. Autophagy in health and disease: a double-edged sword. Science 2004, 306:990-995.
    • (2004) Science , vol.306 , pp. 990-995
    • Shintani, T.1    Klionsky, D.J.2
  • 45
    • 0030580411 scopus 로고    scopus 로고
    • Enhancement of immunoreactivity for NF-kappa B in human cerebral infarctions
    • Terai K., Matsuo A., McGeer E.G., McGeer P.L. Enhancement of immunoreactivity for NF-kappa B in human cerebral infarctions. Brain Res 1996, 739:343-349.
    • (1996) Brain Res , vol.739 , pp. 343-349
    • Terai, K.1    Matsuo, A.2    McGeer, E.G.3    McGeer, P.L.4
  • 47
    • 67449138379 scopus 로고    scopus 로고
    • The protective mechanism of progesterone on blood-brain barrier in cerebral ischemia in rats
    • Wang J., Jiang C., Li X., Liu C., Cheng N., Hao Y. The protective mechanism of progesterone on blood-brain barrier in cerebral ischemia in rats. Brain Res Bull 2009, 79:426-430.
    • (2009) Brain Res Bull , vol.79 , pp. 426-430
    • Wang, J.1    Jiang, C.2    Li, X.3    Liu, C.4    Cheng, N.5    Hao, Y.6
  • 48
    • 76749167941 scopus 로고    scopus 로고
    • Atorvastatin protects rat brains against permanent focal ischemia and downregulates HMGB1, HMGB1 receptors (RAGE and TLR4), NF-kappaB expression
    • Wang L., Zhang X., Liu L., Yang R., Cui L., Li M. Atorvastatin protects rat brains against permanent focal ischemia and downregulates HMGB1, HMGB1 receptors (RAGE and TLR4), NF-kappaB expression. Neurosci Lett 2010, 471:152-156.
    • (2010) Neurosci Lett , vol.471 , pp. 152-156
    • Wang, L.1    Zhang, X.2    Liu, L.3    Yang, R.4    Cui, L.5    Li, M.6
  • 49
    • 4444351598 scopus 로고    scopus 로고
    • Necrosis, apoptosis and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats
    • Wei L., Ying D.J., Cui L., Langsdorf J., Yu S.P. Necrosis, apoptosis and hybrid death in the cortex and thalamus after barrel cortex ischemia in rats. Brain Res 2004, 1022:54-61.
    • (2004) Brain Res , vol.1022 , pp. 54-61
    • Wei, L.1    Ying, D.J.2    Cui, L.3    Langsdorf, J.4    Yu, S.P.5
  • 50
    • 33645111789 scopus 로고    scopus 로고
    • Cell death mechanism and protective effect of erythropoietin after focal ischemia in the whisker-barrel cortex of neonatal rats
    • Wei L., Han B.H., Li Y., Keogh C.L., Holtzman D.M., Yu S.P. Cell death mechanism and protective effect of erythropoietin after focal ischemia in the whisker-barrel cortex of neonatal rats. J Pharmacol Exp Ther 2006, 317:109-116.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 109-116
    • Wei, L.1    Han, B.H.2    Li, Y.3    Keogh, C.L.4    Holtzman, D.M.5    Yu, S.P.6
  • 51
    • 50249189191 scopus 로고    scopus 로고
    • Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways
    • Wen Y.D., Sheng R., Zhang L.S., Han R., Zhang X., Zhang X.D., Han F., Fukunaga K., Qin Z.H. Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways. Autophagy 2008, 4:762-769.
    • (2008) Autophagy , vol.4 , pp. 762-769
    • Wen, Y.D.1    Sheng, R.2    Zhang, L.S.3    Han, R.4    Zhang, X.5    Zhang, X.D.6    Han, F.7    Fukunaga, K.8    Qin, Z.H.9
  • 52
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • Wullschleger S., Loewith R., Hall M.N. TOR signaling in growth and metabolism. Cell 2006, 124:471-484.
    • (2006) Cell , vol.124 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 53
    • 33745852665 scopus 로고    scopus 로고
    • Alternative pathways of NF-kappaB activation: a double-edged sword in health and disease
    • Xiao G., Rabson A.B., Young W., Qing G., Qu Z. Alternative pathways of NF-kappaB activation: a double-edged sword in health and disease. Cytokine Growth Factor Rev 2006, 17:281-293.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 281-293
    • Xiao, G.1    Rabson, A.B.2    Young, W.3    Qing, G.4    Qu, Z.5
  • 54
    • 34249978518 scopus 로고    scopus 로고
    • Autophagy and NF-kappaB: fight for fate
    • Xiao G. Autophagy and NF-kappaB: fight for fate. Cytokine Growth Factor Rev 2007, 18:233-243.
    • (2007) Cytokine Growth Factor Rev , vol.18 , pp. 233-243
    • Xiao, G.1
  • 55
    • 39149111914 scopus 로고    scopus 로고
    • Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells
    • Zeng M., Zhou J.N. Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells. Cell Signal 2008, 20:659-665.
    • (2008) Cell Signal , vol.20 , pp. 659-665
    • Zeng, M.1    Zhou, J.N.2
  • 56
    • 33847014888 scopus 로고    scopus 로고
    • Phosphoinositide-3-kinase/akt survival signal pathways are implicated in neuronal survival after stroke
    • Zhao H., Sapolsky R.M., Steinberg G.K. Phosphoinositide-3-kinase/akt survival signal pathways are implicated in neuronal survival after stroke. Mol Neurobiol 2006, 34:249-270.
    • (2006) Mol Neurobiol , vol.34 , pp. 249-270
    • Zhao, H.1    Sapolsky, R.M.2    Steinberg, G.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.