Atorvastatin protects rat brains against permanent focal ischemia and downregulates HMGB1, HMGB1 receptors (RAGE and TLR4), NF-κB expression

Neuroscience Letters

Volumn 471, Issue 3, 2010, Pages 152-156

  Wang, Lina ^a   Zhang, Xiangjian ^a   Liu, Lingling ^a   Yang, Rui ^a   Cui, Lili ^a   Li, Min ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Atorvastatin; Cerebral ischemia; High mobility group box 1; Neuroprotection

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; ATORVASTATIN; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATTENUATION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN WATER; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG MECHANISM; DRUG MEGADOSE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; LOW DRUG DOSE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; BRAIN EDEMA; BRAIN INFARCTION; BRAIN ISCHEMIA; DOWN-REGULATION; HEPTANOIC ACIDS; HMGB1 PROTEIN; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; NEUROPROTECTIVE AGENTS; NF-KAPPA B; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, IMMUNOLOGIC; TOLL-LIKE RECEPTOR 4;

EID: 76749167941     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.01.030     Document Type: Article

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