메뉴 건너뛰기




Volumn 180, Issue 11, 2008, Pages 7265-7275

IL-7/anti-IL-7 mAb complexes restore T cell development and induce homeostatic T cell expansion without lymphopenia

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE ANTIBODY; INTERLEUKIN 7; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN;

EID: 47249097468     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.11.7265     Document Type: Article
Times cited : (108)

References (69)
  • 1
    • 18944379196 scopus 로고    scopus 로고
    • The many faces of IL-7: From lymphopoiesis to peripheral T cell maintenance
    • Fry, T. J., and C. L. Mackall. 2005. The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance. J. Immunol. 174: 6571-6576.
    • (2005) J. Immunol , vol.174 , pp. 6571-6576
    • Fry, T.J.1    Mackall, C.L.2
  • 2
    • 0029962080 scopus 로고    scopus 로고
    • The interleukin-2 receptor Y-chain: Its role in the multiple cytokine receptor complexes and T cell development in XSCID
    • Sugamura, K., H. Asao, M. Kondo, N. Tanaka, N. Ishii, K. Ohbo, M. Nakamura, and T. Takeshita. 1996. The interleukin-2 receptor Y-chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID. Annu. Rev. Immunol. 14: 179-205.
    • (1996) Annu. Rev. Immunol , vol.14 , pp. 179-205
    • Sugamura, K.1    Asao, H.2    Kondo, M.3    Tanaka, N.4    Ishii, N.5    Ohbo, K.6    Nakamura, M.7    Takeshita, T.8
  • 3
    • 4544241811 scopus 로고    scopus 로고
    • Tolerance, not immunity, crucially depends on IL-2
    • Malek, T. R., and A. L. Bayer. 2004. Tolerance, not immunity, crucially depends on IL-2. Nat. Rev. Immunol. 4: 665-674.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 665-674
    • Malek, T.R.1    Bayer, A.L.2
  • 4
    • 0030903027 scopus 로고    scopus 로고
    • Human immune disorder arising from mutation of the α-chain of the intcrleukin-2 receptor
    • Sharfe, N., H. K. Dadi, M. Shahar, and C. M. Roifman. 1997. Human immune disorder arising from mutation of the α-chain of the intcrleukin-2 receptor. Proc. Natl. Acad. Sci. USA 94: 3168-3171.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3168-3171
    • Sharfe, N.1    Dadi, H.K.2    Shahar, M.3    Roifman, C.M.4
  • 6
    • 16844386089 scopus 로고    scopus 로고
    • Regulation of mature T cell homeostasis
    • Surh, C. D., and J. Sprent. 2005. Regulation of mature T cell homeostasis. Semin Immunol. 17: 183-191.
    • (2005) Semin Immunol , vol.17 , pp. 183-191
    • Surh, C.D.1    Sprent, J.2
  • 7
    • 0028929565 scopus 로고
    • Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
    • von Freeden-Jeffry, U., P. Vieira, L. A. Lucian, T. McNeil, S. E. G. Burdach, and R. Murray. 1995. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J. Exp. Med. 181: 1519-1526.
    • (1995) J. Exp. Med , vol.181 , pp. 1519-1526
    • von Freeden-Jeffry, U.1    Vieira, P.2    Lucian, L.A.3    McNeil, T.4    Burdach, S.E.G.5    Murray, R.6
  • 9
    • 0032471712 scopus 로고    scopus 로고
    • Durability of complete responses in patients with melastatic cancer treated with high-dose interleukin-2: Identification of the antigens mediating response
    • Rosenberg, S. A., J. C. Yang, D. E. White, and S. M. Steinberg. 1998. Durability of complete responses in patients with melastatic cancer treated with high-dose interleukin-2: identification of the antigens mediating response. Ann. Surg. 228: 307-319.
    • (1998) Ann. Surg , vol.228 , pp. 307-319
    • Rosenberg, S.A.1    Yang, J.C.2    White, D.E.3    Steinberg, S.M.4
  • 10
  • 11
    • 23244440386 scopus 로고    scopus 로고
    • High-affinity CD25-binding IL-2 mutants potently stimulate persistent T cell growth
    • Rao, B. M., I. Driver, D. A. Lauffenburger, and K. D. Wittrup. 2005. High-affinity CD25-binding IL-2 mutants potently stimulate persistent T cell growth. Biochemistry 44: 10696-10701.
    • (2005) Biochemistry , vol.44 , pp. 10696-10701
    • Rao, B.M.1    Driver, I.2    Lauffenburger, D.A.3    Wittrup, K.D.4
  • 12
    • 0001365675 scopus 로고
    • Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth A sarcoma model
    • Katre, N. V., M. J. Knauf, and W. J. Laird. 1987. Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth A sarcoma model. Proc. Natl. Acad. Sci. USA 84: 1487-1491.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 1487-1491
    • Katre, N.V.1    Knauf, M.J.2    Laird, W.J.3
  • 14
    • 33645465526 scopus 로고    scopus 로고
    • Selective stimulation of T cell subsets with antibody-cytokine immune complexes
    • Boyman, O., M. Kovar, M. P. Rubinstein, C. D. Surh, and J. Sprent. 2006. Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science 311: 1924-1927.
    • (2006) Science , vol.311 , pp. 1924-1927
    • Boyman, O.1    Kovar, M.2    Rubinstein, M.P.3    Surh, C.D.4    Sprent, J.5
  • 15
    • 0028986977 scopus 로고
    • Cytokine-binding proteins: Stimulating antagonists
    • Klein, B., and H. Brailly. 1995. Cytokine-binding proteins: stimulating antagonists. Immunol. Today 16: 216-220.
    • (1995) Immunol. Today , vol.16 , pp. 216-220
    • Klein, B.1    Brailly, H.2
  • 16
    • 0027239843 scopus 로고
    • Anti-cytokine antibodies as carrier proteins: Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes
    • Finkelman, F. D., K. B. Madden, S. C. Morris, J. M. Holmes, N. Boiani, I. M. Katona, and C. R. Maliszewski. 1993. Anti-cytokine antibodies as carrier proteins: prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. J. Immunol. 151: 1235-1244.
    • (1993) J. Immunol , vol.151 , pp. 1235-1244
    • Finkelman, F.D.1    Madden, K.B.2    Morris, S.C.3    Holmes, J.M.4    Boiani, N.5    Katona, I.M.6    Maliszewski, C.R.7
  • 18
    • 33750335080 scopus 로고    scopus 로고
    • Combined IL-15/IL-15Rα immunotherapy maximizes IL-15 activity in vivo
    • Stoklasek, T. A., K. S. Schluns, and L. Lefrancois. 2006. Combined IL-15/IL-15Rα immunotherapy maximizes IL-15 activity in vivo. J. Immunol. 177: 6072-6080.
    • (2006) J. Immunol , vol.177 , pp. 6072-6080
    • Stoklasek, T.A.1    Schluns, K.S.2    Lefrancois, L.3
  • 20
    • 34547824186 scopus 로고    scopus 로고
    • + T cells differentiate into protective memory-like cells after IL-2 anti IL-2 complex treatment in vivo
    • + T cells differentiate into protective memory-like cells after IL-2 anti IL-2 complex treatment in vivo. J. Exp. Med. 204: 1803-1812.
    • (2007) J. Exp. Med , vol.204 , pp. 1803-1812
    • Kamimura, D.1    Bevan, M.J.2
  • 22
    • 0028215702 scopus 로고
    • The ligand for positive selection of T lymphocytes in the thymus
    • Hogquist, K. A., S. C. Jameson, and M. J. Bevan. 1994. The ligand for positive selection of T lymphocytes in the thymus. Curr. Opin. Immunol. 6: 273-278.
    • (1994) Curr. Opin. Immunol , vol.6 , pp. 273-278
    • Hogquist, K.A.1    Jameson, S.C.2    Bevan, M.J.3
  • 23
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • Pircher, H., K. Bürki, R. Lang, H. Hengartner, and R. M. Zinkemagel. 1989. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 342: 559-561.
    • (1989) Nature , vol.342 , pp. 559-561
    • Pircher, H.1    Bürki, K.2    Lang, R.3    Hengartner, H.4    Zinkemagel, R.M.5
  • 24
    • 0031975635 scopus 로고    scopus 로고
    • Virus-specific MHC-class H-restricted TCR-transgenic mice: Effects on humoral and cellular immune responses after viral infection
    • Oxenius, A., M. F. Bachmann, R. M. Zinkemagel, and H. Hengartner. 1998. Virus-specific MHC-class H-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection. Eur. J. Immunol. 28: 390-400.
    • (1998) Eur. J. Immunol , vol.28 , pp. 390-400
    • Oxenius, A.1    Bachmann, M.F.2    Zinkemagel, R.M.3    Hengartner, H.4
  • 25
    • 78651140453 scopus 로고
    • Studies on mouse leukaemia: The role of the thymus in leukaemogenesis by cell-free leukaemic filtrates
    • Miller, J. F. 1960. Studies on mouse leukaemia: the role of the thymus in leukaemogenesis by cell-free leukaemic filtrates. Br. J. Cancer 14: 93-98.
    • (1960) Br. J. Cancer , vol.14 , pp. 93-98
    • Miller, J.F.1
  • 33
    • 0030874326 scopus 로고    scopus 로고
    • The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression
    • von Freeden-Jeffry, U., N. Solvason, M. Howard, and R. Murray. 1997. The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression. Immunity 7: 147-154.
    • (1997) Immunity , vol.7 , pp. 147-154
    • von Freeden-Jeffry, U.1    Solvason, N.2    Howard, M.3    Murray, R.4
  • 34
    • 0033180491 scopus 로고    scopus 로고
    • The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery
    • Ernst, B., D.-S. Lee, J. M. Chang, J. Sprent, and C. D. Surh. 1999. The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity 11: 173-181.
    • (1999) Immunity , vol.11 , pp. 173-181
    • Ernst, B.1    Lee, D.-S.2    Chang, J.M.3    Sprent, J.4    Surh, C.D.5
  • 36
    • 0034663776 scopus 로고    scopus 로고
    • Naive T cells masquerading as memory cells
    • Murali-Krishna, K., and R. Ahmed. 2000. Naive T cells masquerading as memory cells. J. Immunol. 165: 1733-1737.
    • (2000) J. Immunol , vol.165 , pp. 1733-1737
    • Murali-Krishna, K.1    Ahmed, R.2
  • 37
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
    • Schluns, K. S., W. C. Kieper, S. C. Jameson, and L. Lefrancois. 2000. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat. Immunol. 1: 426-432.
    • (2000) Nat. Immunol , vol.1 , pp. 426-432
    • Schluns, K.S.1    Kieper, W.C.2    Jameson, S.C.3    Lefrancois, L.4
  • 39
    • 0021042615 scopus 로고
    • On the fragmentation of monoclonal IgGl, IgG2a, and IgG2b from BALB/c mice
    • Parham, P. 1983. On the fragmentation of monoclonal IgGl, IgG2a, and IgG2b from BALB/c mice. J. Immunol. 131: 2895-2902.
    • (1983) J. Immunol , vol.131 , pp. 2895-2902
    • Parham, P.1
  • 44
    • 0031740732 scopus 로고    scopus 로고
    • + severe combined immunodeficiency. Nat. Genet. 20: 394-397.
    • + severe combined immunodeficiency. Nat. Genet. 20: 394-397.
  • 45
    • 33646186619 scopus 로고    scopus 로고
    • Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis
    • Ma, A., R. Koka, and P. Burkett. 2006. Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis. Annu. Rev. Immunol. 24: 657-679.
    • (2006) Annu. Rev. Immunol , vol.24 , pp. 657-679
    • Ma, A.1    Koka, R.2    Burkett, P.3
  • 51
    • 0028337496 scopus 로고
    • Administration of recombinant human IL-7 to mice alters the composition of B-Iineage cells and T cell subsets, enhances T cell function, and induces regression of established metastases
    • Komschlies, K. L., T. A. Gregorio, M. E. Gruys, T. C. Back, C. R. Faltynek, and R. H. Wiltrout. 1994. Administration of recombinant human IL-7 to mice alters the composition of B-Iineage cells and T cell subsets, enhances T cell function, and induces regression of established metastases. J. Immunol. 152: 5776-5784.
    • (1994) J. Immunol , vol.152 , pp. 5776-5784
    • Komschlies, K.L.1    Gregorio, T.A.2    Gruys, M.E.3    Back, T.C.4    Faltynek, C.R.5    Wiltrout, R.H.6
  • 52
    • 0035284827 scopus 로고    scopus 로고
    • IL-7 administration alters the CD4:CD8 ratio, increases T cell numbers, and increases T cell function in the absence of activation
    • Geiselhart, L. A., C. A. Humphries, T. A. Gregorio, S. Mou, J. Subleski, and K. L. Komschlies. 2001. IL-7 administration alters the CD4:CD8 ratio, increases T cell numbers, and increases T cell function in the absence of activation. J. Immunol. 166: 3019-3027.
    • (2001) J. Immunol , vol.166 , pp. 3019-3027
    • Geiselhart, L.A.1    Humphries, C.A.2    Gregorio, T.A.3    Mou, S.4    Subleski, J.5    Komschlies, K.L.6
  • 54
    • 0025981025 scopus 로고
    • Administration of IL-7 to mice with cyclophosphamideinduced lymphopenia accelerates lymphocyte repopulation
    • Morrissey, P. J., P. Conlon, S. Braddy, D. E. Williams, A. E. Namen, and D. Y. Mochizuki. 1991. Administration of IL-7 to mice with cyclophosphamideinduced lymphopenia accelerates lymphocyte repopulation. J. Immunol. 146: 1547-1552.
    • (1991) J. Immunol , vol.146 , pp. 1547-1552
    • Morrissey, P.J.1    Conlon, P.2    Braddy, S.3    Williams, D.E.4    Namen, A.E.5    Mochizuki, D.Y.6
  • 56
    • 0029794831 scopus 로고    scopus 로고
    • Enhancement of thymopoiesis after bone marrow transplant by in vivo interleukin-7
    • Bolotin, E., M. Smogorzewska, S. Smith, M. Widmer, and K. Weinberg. 1996. Enhancement of thymopoiesis after bone marrow transplant by in vivo interleukin-7. Blood 88: 1887-1894.
    • (1996) Blood , vol.88 , pp. 1887-1894
    • Bolotin, E.1    Smogorzewska, M.2    Smith, S.3    Widmer, M.4    Weinberg, K.5
  • 57
    • 0035282766 scopus 로고    scopus 로고
    • IL-7 increases both thymic-dependent and thymic-independent T-cell regeneration after bone marrow transplantation
    • Mackall, C. L., T. J. Fry, C. Bare, P. Morgan, A. Galbraith, and R. E. Gress. 2001. IL-7 increases both thymic-dependent and thymic-independent T-cell regeneration after bone marrow transplantation. Blood 97: 1491-1497.
    • (2001) Blood , vol.97 , pp. 1491-1497
    • Mackall, C.L.1    Fry, T.J.2    Bare, C.3    Morgan, P.4    Galbraith, A.5    Gress, R.E.6
  • 60
    • 34848875495 scopus 로고    scopus 로고
    • Interleukin-7 immunotherapy
    • Sportes, C, and R. E. Gress. 2007. Interleukin-7 immunotherapy. Adv. Exp. Med. Biol. 601: 321-333.
    • (2007) Adv. Exp. Med. Biol , vol.601 , pp. 321-333
    • Sportes, C.1    Gress, R.E.2
  • 61
    • 0027372545 scopus 로고
    • Enhancement of anti-tumor activity of recombinant interleukin-2 (rIL-2) by immunocomplexing with a monoclonal antibody against rIL-2
    • Sato, J., N. Hamaguchi, K. Doken, K. Gotoh, K. Ootsu, S. Iwasa, Y. Ogawa, and H. Toguchi. 1993. Enhancement of anti-tumor activity of recombinant interleukin-2 (rIL-2) by immunocomplexing with a monoclonal antibody against rIL-2. Biotherapy 6: 225-231.
    • (1993) Biotherapy , vol.6 , pp. 225-231
    • Sato, J.1    Hamaguchi, N.2    Doken, K.3    Gotoh, K.4    Ootsu, K.5    Iwasa, S.6    Ogawa, Y.7    Toguchi, H.8
  • 62
    • 0028134983 scopus 로고
    • An anti-IL-2 antibody increases serum half-life and improves anti-tumor efficacy of human recombinant interIeukin-2
    • Courtney, L. P., J. L. Phelps, and L. M. Karavodin. 1994. An anti-IL-2 antibody increases serum half-life and improves anti-tumor efficacy of human recombinant interIeukin-2. Immunopharmacology 28: 223-232.
    • (1994) Immunopharmacology , vol.28 , pp. 223-232
    • Courtney, L.P.1    Phelps, J.L.2    Karavodin, L.M.3
  • 63
    • 0032101925 scopus 로고    scopus 로고
    • Exogenous interleukin 7 as a proliferative stimulant of early precursor B cells in mouse bone marrow: Efficacy of IL-7 injection, IL-7 infusion and IL-7-anti-IL-7 antibody complexes
    • Valenzona, H. O., S. Dhanoa, F. D. Finkelman, and D. G. Osmond. 1998. Exogenous interleukin 7 as a proliferative stimulant of early precursor B cells in mouse bone marrow: efficacy of IL-7 injection, IL-7 infusion and IL-7-anti-IL-7 antibody complexes. Cylokine 10: 404-412.
    • (1998) Cylokine , vol.10 , pp. 404-412
    • Valenzona, H.O.1    Dhanoa, S.2    Finkelman, F.D.3    Osmond, D.G.4
  • 64
    • 33745306112 scopus 로고    scopus 로고
    • IL-2 in vivo activities and antitumor efficacy enhanced by an anti-IL-2 mAb
    • Kamimura, D., Y. Sawa, M. Sato, E. Agung, T. Hirano, and M. Murakami. 2006. IL-2 in vivo activities and antitumor efficacy enhanced by an anti-IL-2 mAb. J. Immunol. 177:306-314.
    • (2006) J. Immunol , vol.177 , pp. 306-314
    • Kamimura, D.1    Sawa, Y.2    Sato, M.3    Agung, E.4    Hirano, T.5    Murakami, M.6
  • 65
    • 40449139771 scopus 로고    scopus 로고
    • Cutting edge: Mechanism of enhancement of in vivo cytokine effects by anti-cytokine monoclonal antibodies
    • Phelan, J. D., T. Orekov, and F. D. Finkelman. 2008. Cutting edge: mechanism of enhancement of in vivo cytokine effects by anti-cytokine monoclonal antibodies. J. Immunol. 180: 44-48.
    • (2008) J. Immunol , vol.180 , pp. 44-48
    • Phelan, J.D.1    Orekov, T.2    Finkelman, F.D.3
  • 66
    • 34548229364 scopus 로고    scopus 로고
    • FcRn: The neonatal Fc receptor comes of age
    • Roopenian, D. C, and S. Akilesh. 2007. FcRn: the neonatal Fc receptor comes of age. Nat. Rev. Immunol. 7: 715-725.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 715-725
    • Roopenian, D.C.1    Akilesh, S.2
  • 67
    • 0038629350 scopus 로고    scopus 로고
    • Immunocytokines: Amplification of anti-cancer immunity
    • Davis, C. B., and S. D. Gillies. 2003. Immunocytokines: amplification of anti-cancer immunity. Cancer Immunol. Immunother. 52: 297-308.
    • (2003) Cancer Immunol. Immunother , vol.52 , pp. 297-308
    • Davis, C.B.1    Gillies, S.D.2
  • 68
    • 8644240039 scopus 로고    scopus 로고
    • Anti-body-cytokine fusion proteins: Innovative weapons in the war against cancer
    • Dela Cruz, J. S., T. H. Huang, M. L. Penichet, and S. L. Morrison. 2004. Anti-body-cytokine fusion proteins: innovative weapons in the war against cancer. Clin. Exp. Med. 4: 57-64.
    • (2004) Clin. Exp. Med , vol.4 , pp. 57-64
    • Dela Cruz, J.S.1    Huang, T.H.2    Penichet, M.L.3    Morrison, S.L.4
  • 69
    • 9644295710 scopus 로고    scopus 로고
    • Cytokines and immunodeficiency diseases: Critical roles of the γ (c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways
    • Kovanen, P. E., and W. J. Leonard. 2004. Cytokines and immunodeficiency diseases: critical roles of the γ (c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways. Immunol. Rev. 202: 67-83.
    • (2004) Immunol. Rev , vol.202 , pp. 67-83
    • Kovanen, P.E.1    Leonard, W.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.