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Volumn 55, Issue 2, 2010, Pages 484-495

Hepatocellular carcinoma immunopathogenesis: Clinical evidence for global T cell defects and an immunomodulatory role for soluble CD25 (sCD25)

Author keywords

IL 2 signaling; Liver cancer; Serum; Soluble factors; Soluble IL 2 receptor alpha chain (sIL 2RA); T cell immunosuppression; Tumor tolerance

Indexed keywords

ADENOSINE TRIPHOSPHATE; GAMMA INTERFERON; INTERLEUKIN 2 RECEPTOR ALPHA; IL2RA PROTEIN, HUMAN; TUMOR MARKER;

EID: 76849085439     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-009-0955-5     Document Type: Article
Times cited : (32)

References (25)
  • 1
    • 0035888074 scopus 로고    scopus 로고
    • Estimating the world cancer burden: Globocan 2000
    • DOI 10.1002/ijc.1440
    • DM Parkin F Bray J Ferlay, et al. 2001 Estimating the world cancer burden: Globocan 2000 Int J Cancer 94 153 156 10.1002/ijc.1440 1:CAS:528:DC%2BD3MXntVGlu78%3D 11668491 (Pubitemid 32911406)
    • (2001) International Journal of Cancer , vol.94 , Issue.2 , pp. 153-156
    • Maxwell Parkin, D.1    Bray, F.2    Ferlay, J.3    Pisani, P.4
  • 2
    • 0642303165 scopus 로고    scopus 로고
    • The continuing increase in the incidence of hepatocellular carcinoma in the United States: An update
    • 14623619
    • HB El-Serag JA Davila NJ Petersen KA McGlynn 2003 The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update Ann Intern Med 139 817 823 14623619
    • (2003) Ann Intern Med , vol.139 , pp. 817-823
    • El-Serag, H.B.1    Davila, J.A.2    Petersen, N.J.3    McGlynn, K.A.4
  • 4
    • 0141491273 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • DOI 10.1016/S0140-6736(03)14964-1
    • JM Llovet A Burroughs J Bruix 2003 Hepatocellular carcinoma Lancet 362 1907 1917 10.1016/S0140-6736(03)14964-1 14667750 (Pubitemid 37518510)
    • (2003) Lancet , vol.362 , Issue.9399 , pp. 1907-1917
    • Llovet, J.M.1    Burroughs, A.2    Bruix, J.3
  • 5
    • 47949116252 scopus 로고    scopus 로고
    • Sorafenib in advanced hepatocellular carcinoma
    • 10.1056/NEJMoa0708857 1:CAS:528:DC%2BD1cXovFWjsL8%3D 18650514
    • JM Llovet S Ricci V Mazzaferro P Hilgard E Gane JF Blanc, et al. 2008 Sorafenib in advanced hepatocellular carcinoma N Engl J Med 359 378 390 10.1056/NEJMoa0708857 1:CAS:528:DC%2BD1cXovFWjsL8%3D 18650514
    • (2008) N Engl J Med , vol.359 , pp. 378-390
    • Llovet, J.M.1    Ricci, S.2    Mazzaferro, V.3    Hilgard, P.4    Gane, E.5    Blanc, J.F.6
  • 6
    • 44749089874 scopus 로고    scopus 로고
    • Molecular targeted therapies in hepatocellular carcinoma: From pre-clinical models to clinical trials
    • 10.1016/j.jhep.2008.04.006 1:CAS:528:DC%2BD1cXmvFelsr0%3D 18486262
    • P Newell A Villanueva JM Llovet 2008 Molecular targeted therapies in hepatocellular carcinoma: from pre-clinical models to clinical trials J Hepatol 49 1 5 10.1016/j.jhep.2008.04.006 1:CAS:528:DC%2BD1cXmvFelsr0%3D 18486262
    • (2008) J Hepatol , vol.49 , pp. 1-5
    • Newell, P.1    Villanueva, A.2    Llovet, J.M.3
  • 7
    • 0037472473 scopus 로고    scopus 로고
    • Tumor antigen-specific T cells and cancer immunotherapy: Current issues and future prospects
    • DOI 10.1016/S0264-410X(02)00598-4, PII S0264410X02005984
    • M Kalos 2003 Tumor antigen-specific T cells and cancer immunotherapy: current issues and future prospects Vaccine 21 781 786 10.1016/S0264-410X(02) 00598-4 1:CAS:528:DC%2BD3sXjtFKlsg%3D%3D 12531359 (Pubitemid 36091997)
    • (2003) Vaccine , vol.21 , Issue.7-8 , pp. 781-786
    • Kalos, M.1
  • 8
    • 0031890627 scopus 로고    scopus 로고
    • Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration
    • DOI 10.1002/hep.510270214
    • Y Wada O Nakashima R Kutami O Yamamoto M Kojiro 1998 Clinicopathological study on hepatocellular carcinoma with lymphocytic infiltration Hepatology 27 407 414 10.1002/hep.510270214 1:STN:280:DyaK1c7it1Cksg%3D%3D 9462638 (Pubitemid 28081054)
    • (1998) Hepatology , vol.27 , Issue.2 , pp. 407-414
    • Wada, Y.1    Nakashima, O.2    Kutami, R.3    Yamamoto, O.4    Kojiro, M.5
  • 9
    • 34248995493 scopus 로고    scopus 로고
    • Hepatocellular carcinoma cell supernatants increase expansion and function of CD4+CD25+ regulatory T cells
    • 1:CAS:528:DC%2BD2sXltlejsb4%3D 17372588
    • M Cao R Cabrera Y Xu R Firpi H Zhu C Liu, et al. 2007 Hepatocellular carcinoma cell supernatants increase expansion and function of CD4+CD25+ regulatory T cells Lab Invest 87 582 590 1:CAS:528:DC%2BD2sXltlejsb4%3D 17372588
    • (2007) Lab Invest , vol.87 , pp. 582-590
    • Cao, M.1    Cabrera, R.2    Xu, Y.3    Firpi, R.4    Zhu, H.5    Liu, C.6
  • 10
    • 16844378685 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma
    • DOI 10.1158/0008-5472.CAN-04-3232
    • LA Ormandy T Hillemann H Wedemeyer, et al. 2005 Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma Cancer Res 65 6 2457 2464 10.1158/0008-5472.CAN-04-3232 1:CAS:528: DC%2BD2MXisFGnsL0%3D 15781662 (Pubitemid 40490158)
    • (2005) Cancer Research , vol.65 , Issue.6 , pp. 2457-2464
    • Ormandy, L.1    Hillemann, T.2    Wedemeyer, H.3    Manns, M.P.4    Greten, T.F.5    Korangy, F.6
  • 13
    • 28844480321 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma
    • DOI 10.1002/hep.20933
    • J Bruix M Sherman 2005 Practice guidelines committee, American association for the study of liver diseases. Management of hepatocellular carcinoma Hepatology 42 1208 1236 10.1002/hep.20933 16250051 (Pubitemid 43112690)
    • (2005) Hepatology , vol.42 , Issue.5 , pp. 1208-1236
    • Bruix, J.1    Sherman, M.2
  • 15
    • 67649172198 scopus 로고    scopus 로고
    • Using an immune functional assay to differentiate acute cellular rejection from recurrent hepatitis C in liver transplant patients
    • 10.1002/lt.21666 19177434
    • R Cabrera M Ararat C Soldevila-Pico L Dixon JJ Pan R Firpi, et al. 2009 Using an immune functional assay to differentiate acute cellular rejection from recurrent hepatitis C in liver transplant patients Liver Transpl 15 216 222 10.1002/lt.21666 19177434
    • (2009) Liver Transpl , vol.15 , pp. 216-222
    • Cabrera, R.1    Ararat, M.2    Soldevila-Pico, C.3    Dixon, L.4    Pan, J.J.5    Firpi, R.6
  • 16
    • 46049098560 scopus 로고    scopus 로고
    • + T cells
    • DOI 10.1053/j.gastro.2008.03.020, PII S0016508508004563
    • B Hoechst LA Ormandy M Ballmaier F Lehner C Krüger MP Manns, et al. 2008 A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4+CD25+Foxp3+ T cells Gastroenterology 135 234 243 10.1053/j.gastro.2008.03.020 1:CAS:528:DC%2BD1cXps1Wltb0%3D 18485901 (Pubitemid 351899008)
    • (2008) Gastroenterology , vol.135 , Issue.1 , pp. 234-243
    • Hoechst, B.1    Ormandy, L.A.2    Ballmaier, M.3    Lehner, F.4    Kruger, C.5    Manns, M.P.6    Greten, T.F.7    Korangy, F.8
  • 17
    • 25644446532 scopus 로고    scopus 로고
    • Soluble IL-2 receptor in cancer
    • 10.2741/1461
    • S Murakami 2004 Soluble IL-2 receptor in cancer Front Biosci 1 9 3085 3090 10.2741/1461
    • (2004) Front Biosci , vol.1 , Issue.9 , pp. 3085-3090
    • Murakami, S.1
  • 18
    • 63149109244 scopus 로고    scopus 로고
    • Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses
    • 1:CAS:528:DC%2BD1MXnsVeqsw%3D%3D 19155502
    • LM Maier DE Anderson CA Severson C Baecher-Allan B Healy DV Liu, et al. 2009 Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses J Immunol 182 1541 1547 1:CAS:528: DC%2BD1MXnsVeqsw%3D%3D 19155502
    • (2009) J Immunol , vol.182 , pp. 1541-1547
    • Maier, L.M.1    Anderson, D.E.2    Severson, C.A.3    Baecher-Allan, C.4    Healy, B.5    Liu, D.V.6
  • 19
    • 0024332062 scopus 로고
    • Soluble interleukin 2 receptors released from mitogen stimulated human peripheral blood lymphocytes bind interleukin 2 and inhibit IL2 dependent cell proliferation
    • 10.3109/08820138909045783 1:CAS:528:DyaK3cXltlCrsQ%3D%3D 2583751
    • RK Chopra DC Powers NE Kendig WH Adler JE Nagel 1989 Soluble interleukin 2 receptors released from mitogen stimulated human peripheral blood lymphocytes bind interleukin 2 and inhibit IL2 dependent cell proliferation Immunol Invest 18 961 973 10.3109/08820138909045783 1:CAS:528:DyaK3cXltlCrsQ%3D%3D 2583751
    • (1989) Immunol Invest , vol.18 , pp. 961-973
    • Chopra, R.K.1    Powers, D.C.2    Kendig, N.E.3    Adler, W.H.4    Nagel, J.E.5
  • 20
    • 0022976693 scopus 로고
    • The released interleukin 2 receptor binds interleukin 2 efficiently
    • 1:CAS:528:DyaL2sXkvVCgsw%3D%3D 3023487
    • LA Rubin G Jay DL Nelson 1986 The released interleukin 2 receptor binds interleukin 2 efficiently J Immunol 137 12 3841 3844 1:CAS:528: DyaL2sXkvVCgsw%3D%3D 3023487
    • (1986) J Immunol , vol.137 , Issue.12 , pp. 3841-3844
    • Rubin, L.A.1    Jay, G.2    Nelson, D.L.3
  • 21
    • 6344268944 scopus 로고    scopus 로고
    • Mechanisms of soluble cytokine receptor generation
    • 1:CAS:528:DC%2BD2cXos1Gitbg%3D 15494479
    • SJ Levine 2004 Mechanisms of soluble cytokine receptor generation J Immunol 173 5343 5348 1:CAS:528:DC%2BD2cXos1Gitbg%3D 15494479
    • (2004) J Immunol , vol.173 , pp. 5343-5348
    • Levine, S.J.1
  • 23
    • 0036291101 scopus 로고    scopus 로고
    • Circulating IL-6 and sIL-6R in patients with hepatocellular carcinoma
    • 1:CAS:528:DC%2BD38XlvVOjurc%3D 12095927
    • L Giannitrapani M Cervello M Soresi M Notarbartolo M La Rosa L Virruso, et al. 2002 Circulating IL-6 and sIL-6R in patients with hepatocellular carcinoma Ann N Y Acad Sci 963 46 52 1:CAS:528:DC%2BD38XlvVOjurc%3D 12095927
    • (2002) Ann N y Acad Sci , vol.963 , pp. 46-52
    • Giannitrapani, L.1    Cervello, M.2    Soresi, M.3    Notarbartolo, M.4    La Rosa, M.5    Virruso, L.6
  • 24
    • 38149076482 scopus 로고    scopus 로고
    • Serum soluble IL-2 receptor alpha in human cancer of adults and children: A review
    • 10.1080/13547500701674063 1:CAS:528:DC%2BD1cXksVKktA%3D%3D 17906988
    • E Bien A Balcerska 2008 Serum soluble IL-2 receptor alpha in human cancer of adults and children: a review Biomarkers 13 1 26 10.1080/13547500701674063 1:CAS:528:DC%2BD1cXksVKktA%3D%3D 17906988
    • (2008) Biomarkers , vol.13 , pp. 1-26
    • Bien, E.1    Balcerska, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.