Down-regulation of dorsal striatal RhoA activity and impairment of working memory in middle-aged rats

Neurobiology of Learning and Memory

Volumn 103, Issue , 2013, Pages 3-10

  Kang, Shuo ^a   Ling, Qing Lan ^a   Liu, Wen Tao ^b   Lu, Bin ^a   Liu, Yao ^a   He, Lin ^b   Liu, Jing Gen ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Aging; Dorsal Striatum; LTP; Neuroplasticity; PBS; RhoA; ROCK; SD; Working memory

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; BRAIN PROTEIN; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

AGE DISTRIBUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE ACTIVITY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME REGULATION; HIPPOCAMPUS; LONG TERM MEMORY; MALE; MAZE TEST; MEMORY DISORDER; MIDDLE AGED; NONHUMAN; PREFRONTAL CORTEX; RAT; SENSORIMOTOR CORTEX; SPATIAL MEMORY; TASK PERFORMANCE; WORKING MEMORY;

AGE FACTORS; AGING; AMIDES; ANIMALS; CORPUS STRIATUM; DOWN-REGULATION; ENZYME INHIBITORS; MAZE LEARNING; MEMORY, SHORT-TERM; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 84877326309     PISSN: 10747427     EISSN: 10959564     Source Type: Journal    
DOI: 10.1016/j.nlm.2013.03.005     Document Type: Article

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